ID27044A - Derivatif indole sebagai penghambat pada faktor xa - Google Patents

Derivatif indole sebagai penghambat pada faktor xa

Info

Publication number: ID27044A
Authority: ID; Indonesia
Prior art keywords: objectors; factor; indole derivatives; indole; derivatives
Prior art date: 1997-12-24

Application number

IDW20001225A

Other languages

English (en)

Indonesian (id)

Inventor

Elisabeth Defossa

Uwe Heinelt

Otmar Klingler

Gerhard Zoller

Fahad Al-Obeidi

Armin Walser

Peter Wildgoose

Hans Matter

Original Assignee

Aventis Pharma Gmbh

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1997-12-24

Filing date

1998-12-10

Publication date

2001-02-22

1998-12-10 Application filed by Aventis Pharma Gmbh filed Critical Aventis Pharma Gmbh

2001-02-22 Publication of ID27044A publication Critical patent/ID27044A/id

Links

108010074860 Factor Xa Proteins 0.000 title 1
SIKJAQJRHWYJAI-UHFFFAOYSA-N Indole Chemical class C1=CC=C2NC=CC2=C1 SIKJAQJRHWYJAI-UHFFFAOYSA-N 0.000 title 1
229940054051 antipsychotic indole derivative Drugs 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
- C07D209/42—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing aromatic rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Life Sciences & Earth Sciences (AREA)
Public Health (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Hematology (AREA)
Diabetes (AREA)
Urology & Nephrology (AREA)
Vascular Medicine (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Indole Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)

IDW20001225A 1997-12-24 1998-12-10 Derivatif indole sebagai penghambat pada faktor xa ID27044A (id)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
EP97122901		1997-12-24

Publications (1)

Publication Number	Publication Date
ID27044A true ID27044A (id)	2001-02-22

Family

ID=8227884

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IDW20001225A ID27044A (id)	1997-12-24	1998-12-10	Derivatif indole sebagai penghambat pada faktor xa

Country Status (28)

Country	Link
US (1)	US6337344B1 (cs)
EP (1)	EP1042287B1 (cs)
JP (1)	JP4589529B2 (cs)
KR (1)	KR100608472B1 (cs)
CN (1)	CN1220681C (cs)
AR (1)	AR018031A1 (cs)
AT (1)	ATE293599T1 (cs)
AU (1)	AU743881B2 (cs)
BR (1)	BR9814340B1 (cs)
CA (1)	CA2316172C (cs)
CZ (1)	CZ298827B6 (cs)
DE (1)	DE69829879T2 (cs)
DK (1)	DK1042287T3 (cs)
ES (1)	ES2241194T3 (cs)
HU (1)	HU227568B1 (cs)
ID (1)	ID27044A (cs)
IL (1)	IL136954A0 (cs)
MY (1)	MY120064A (cs)
NO (1)	NO316912B1 (cs)
NZ (1)	NZ505370A (cs)
PL (1)	PL195682B1 (cs)
PT (1)	PT1042287E (cs)
RU (1)	RU2225397C2 (cs)
SI (1)	SI1042287T1 (cs)
TR (1)	TR200001954T2 (cs)
TW (1)	TWI241294B (cs)
WO (1)	WO1999033800A1 (cs)
ZA (1)	ZA9811759B (cs)

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EP1127884A1 (en)	2000-02-26	2001-08-29	Aventis Pharma Deutschland GmbH	Novel malonic acid derivatives, processes for their preparation, their use as inhibitor of factor XA activity and pharmaceutical compositions containing them
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DE10147672A1 (de) *	2001-09-27	2003-04-10	Bayer Ag	Substituierte 2,5-Diamidoindole und ihre Verwendung
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US7446210B2 (en)	2004-10-26	2008-11-04	Janssen Pharmaceutica N.V.	Factor Xa compounds
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EP2069289B1 (de) *	2006-09-13	2013-10-02	Sanofi	ISOSERINDERIVATE ALS INHIBITOREN DES KOAGULATIONSFAKTORS IXa
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US9353113B2 (en)	2011-03-18	2016-05-31	Ono Pharmaceutical Co., Ltd.	Tetrahydrocarboline derivative
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US10632209B2 (en)	2017-11-10	2020-04-28	The Regents Of The University Of Michigan	ASH1L inhibitors and methods of treatment therewith
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1998
- 1998-12-10 BR BRPI9814340-9A patent/BR9814340B1/pt not_active IP Right Cessation
- 1998-12-10 IL IL13695498A patent/IL136954A0/xx not_active IP Right Cessation
- 1998-12-10 WO PCT/EP1998/008030 patent/WO1999033800A1/en not_active Ceased
- 1998-12-10 CA CA002316172A patent/CA2316172C/en not_active Expired - Fee Related
- 1998-12-10 DE DE69829879T patent/DE69829879T2/de not_active Expired - Lifetime
- 1998-12-10 NZ NZ505370A patent/NZ505370A/en not_active IP Right Cessation
- 1998-12-10 ID IDW20001225A patent/ID27044A/id unknown
- 1998-12-10 CZ CZ20002310A patent/CZ298827B6/cs not_active IP Right Cessation
- 1998-12-10 AU AU20528/99A patent/AU743881B2/en not_active Ceased
- 1998-12-10 AT AT98965244T patent/ATE293599T1/de active
- 1998-12-10 PL PL98341400A patent/PL195682B1/pl not_active IP Right Cessation
- 1998-12-10 US US09/582,344 patent/US6337344B1/en not_active Expired - Lifetime
- 1998-12-10 JP JP2000526484A patent/JP4589529B2/ja not_active Expired - Fee Related
- 1998-12-10 SI SI9830771T patent/SI1042287T1/xx unknown
- 1998-12-10 KR KR1020007007084A patent/KR100608472B1/ko not_active Expired - Fee Related
- 1998-12-10 CN CNB988126532A patent/CN1220681C/zh not_active Expired - Fee Related
- 1998-12-10 PT PT98965244T patent/PT1042287E/pt unknown
- 1998-12-10 RU RU2000119774/04A patent/RU2225397C2/ru not_active IP Right Cessation
- 1998-12-10 ES ES98965244T patent/ES2241194T3/es not_active Expired - Lifetime
- 1998-12-10 TR TR2000/01954T patent/TR200001954T2/xx unknown
- 1998-12-10 HU HU0100723A patent/HU227568B1/hu not_active IP Right Cessation
- 1998-12-10 EP EP98965244A patent/EP1042287B1/en not_active Expired - Lifetime
- 1998-12-10 DK DK98965244T patent/DK1042287T3/da active
- 1998-12-22 ZA ZA9811759A patent/ZA9811759B/xx unknown
- 1998-12-22 AR ARP980106607A patent/AR018031A1/es active IP Right Grant
- 1998-12-23 MY MYPI98005870A patent/MY120064A/en unknown
1999
- 1999-02-23 TW TW087121374A patent/TWI241294B/zh not_active IP Right Cessation
2000
- 2000-06-14 NO NO20003057A patent/NO316912B1/no not_active IP Right Cessation

Also Published As

Publication number	Publication date
IL136954A0 (en)	2001-06-14
AU2052899A (en)	1999-07-19
WO1999033800A1 (en)	1999-07-08
HUP0100723A3 (en)	2002-12-28
MY120064A (en)	2005-08-30
CN1283186A (zh)	2001-02-07
JP4589529B2 (ja)	2010-12-01
KR20010033573A (ko)	2001-04-25
PL341400A1 (en)	2001-04-09
TR200001954T2 (tr)	2000-12-21
SI1042287T1 (en)	2005-10-31
NO20003057D0 (no)	2000-06-14
CN1220681C (zh)	2005-09-28
AR018031A1 (es)	2001-10-31
RU2225397C2 (ru)	2004-03-10
ZA9811759B (en)	1999-07-28
JP2001527066A (ja)	2001-12-25
PL195682B1 (pl)	2007-10-31
CZ20002310A3 (cs)	2000-10-11
PT1042287E (pt)	2005-08-31
AU743881B2 (en)	2002-02-07
BR9814340A (pt)	2000-10-03
EP1042287B1 (en)	2005-04-20
DE69829879D1 (de)	2005-05-25
DE69829879T2 (de)	2006-03-02
KR100608472B1 (ko)	2006-08-09
NO20003057L (no)	2000-08-18
NO316912B1 (no)	2004-06-21
DK1042287T3 (da)	2005-08-15
CZ298827B6 (cs)	2008-02-20
HK1033795A1 (en)	2001-09-21
NZ505370A (en)	2002-06-28
US6337344B1 (en)	2002-01-08
CA2316172C (en)	2010-02-02
ATE293599T1 (de)	2005-05-15
HUP0100723A2 (hu)	2001-08-28
HU227568B1 (en)	2011-08-29
TWI241294B (en)	2005-10-11
BR9814340B1 (pt)	2010-07-13
EP1042287A1 (en)	2000-10-11
ES2241194T3 (es)	2005-10-16
CA2316172A1 (en)	1999-07-08

Publication	Publication Date	Title
DE69829879D1 (de)	2005-05-25	Indolderivate als faktor xa inhibitoren
ATE243681T1 (de)	2003-07-15	Benzamidinderivate als faktor xa-inhibitoren
DE60045144D1 (de)	2010-12-09	Stromversorgungseinheit
DE60024166D1 (de)	2005-12-29	Stromversorgungseinheit
NO20021230L (no)	2002-05-21	Faktor Xa inhibitorer
ATE302198T1 (de)	2005-09-15	Guanidine imitatoren als faktor xa inhibitoren
DK0915088T3 (da)	2003-01-27	D-prolinderivater
DE69807353D1 (de)	2002-09-26	Verbesserungen in der glasbeschichtung
ATE310533T1 (de)	2005-12-15	Zusammensetzungen mit stabilem faktor viii
DE60024195D1 (de)	2005-12-29	Stromversorgungseinheit
EE200200135A (et)	2003-04-15	D4 antagonistidena toimivad tienoisoksasolüül- jatienüülpürrasolüülfenoksü-asendatud propüülderivaadid
DE60004363D1 (de)	2003-09-11	Faktor viia inhibitore
DE59909569D1 (de)	2004-07-01	Fördereinheit
DE60021384D1 (de)	2005-08-25	Indolderivate
IS6434A (is)	2002-06-19	Nýjar indól afleiður
NO20020306D0 (no)	2002-01-21	Indolderivater
FI102108B (fi)	1998-10-15	Tuloilmalaite
DE50001156D1 (de)	2003-03-06	Halteeinrichtung
FI990832L (fi)	2000-10-15	Puuntyöstöyksikkö
FI4008U1 (fi)	1999-06-15	Tuloilmalaite
DE60008542D1 (de)	2004-04-01	Produktabgabegerät
DE69821271D1 (de)	2004-03-04	Stromversorgungseinheit
DE50005136D1 (de)	2004-03-04	Halteeinrichtung
FI3085U1 (fi)	1997-09-30	Tuloilmalaite
DK1214312T3 (da)	2004-08-09	5-aminoalkyl- og 5-aminocarbonylsubstituerede indoler