ID30182A - PENGHAMBAT-PENGHAMBAT PIRIDOPIRIDAZINA LEBURAN DARI cGMP FOSFODIESTERASE - Google Patents

PENGHAMBAT-PENGHAMBAT PIRIDOPIRIDAZINA LEBURAN DARI cGMP FOSFODIESTERASE

Info

Publication number: ID30182A
Authority: ID; Indonesia
Prior art keywords: pyropyroidazine; phosphodiesterage; cgmp; lights; displacement
Prior art date: 1999-03-22

Application number

IDW00200102056A

Other languages

English (en)

Inventor

Guixue Yu

John Macor

Hyei-Jha Chung

Michael Humora

Kishta Katipally

Yizhe Wang

Saojin Kim

Original Assignee

Bristol Myers Squibb Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1999-03-22

Filing date

2000-03-09

Publication date

2001-11-08

2000-03-09 Application filed by Bristol Myers Squibb Co filed Critical Bristol Myers Squibb Co

2001-11-08 Publication of ID30182A publication Critical patent/ID30182A/id

Links

ZOOGRGPOEVQQDX-UUOKFMHZSA-N 3',5'-cyclic GMP Chemical compound C([C@H]1O2)OP(O)(=O)O[C@H]1[C@@H](O)[C@@H]2N1C(N=C(NC2=O)N)=C2N=C1 ZOOGRGPOEVQQDX-UUOKFMHZSA-N 0.000 title 1
238000006073 displacement reaction Methods 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
- C07D471/14—Ortho-condensed systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
General Chemical & Material Sciences (AREA)
Veterinary Medicine (AREA)
Chemical Kinetics & Catalysis (AREA)
Life Sciences & Earth Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Public Health (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Endocrinology (AREA)
Reproductive Health (AREA)
Heart & Thoracic Surgery (AREA)
Cardiology (AREA)
Gynecology & Obstetrics (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

IDW00200102056A 1999-03-22 2000-03-09 PENGHAMBAT-PENGHAMBAT PIRIDOPIRIDAZINA LEBURAN DARI cGMP FOSFODIESTERASE ID30182A (id)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US12548899P	1999-03-22	1999-03-22
US14800999P	1999-08-10	1999-08-10

Publications (1)

Publication Number	Publication Date
ID30182A true ID30182A (id)	2001-11-08

Family

ID=26823624

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IDW00200102056A ID30182A (id)	1999-03-22	2000-03-09	PENGHAMBAT-PENGHAMBAT PIRIDOPIRIDAZINA LEBURAN DARI cGMP FOSFODIESTERASE

Country Status (10)

Country	Link
US (1)	US6316438B1 (id)
EP (1)	EP1165521A4 (id)
JP (1)	JP2002540102A (id)
KR (1)	KR20020015030A (id)
CN (1)	CN1161341C (id)
AU (1)	AU765128B2 (id)
CA (1)	CA2368023A1 (id)
ID (1)	ID30182A (id)
UY (1)	UY26071A1 (id)
WO (1)	WO2000056719A1 (id)

Families Citing this family (29)

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US6403597B1 (en)	1997-10-28	2002-06-11	Vivus, Inc.	Administration of phosphodiesterase inhibitors for the treatment of premature ejaculation
US6548490B1 (en) *	1997-10-28	2003-04-15	Vivus, Inc.	Transmucosal administration of phosphodiesterase inhibitors for the treatment of erectile dysfunction
US20040014761A1 (en) *	1997-10-28	2004-01-22	Place Virgil A.	Treatment of female sexual dysfunction with phosphodiesterase inhibitors
US6613768B1 (en) *	1999-04-30	2003-09-02	Lilly Icos Llc	Treatment of female arousal disorder
AU2001276607A1 (en) *	2000-08-11	2002-02-25	Pfizer Inc.	Treatment of the insulin resistance syndrome with selective CGMP PDE5 inhibitors
US6576644B2 (en) *	2000-09-06	2003-06-10	Bristol-Myers Squibb Co.	Quinoline inhibitors of cGMP phosphodiesterase
JP2007501866A (ja) *	2003-06-13	2007-02-01	マイクロバイアインコーポレイテッド	胃腸疾患の治療のための方法および組成物
TW200534879A (en) *	2004-03-25	2005-11-01	Bristol Myers Squibb Co	Coated tablet formulation and method
US7829720B2 (en) *	2004-05-04	2010-11-09	Bristol-Myers Squibb Company	Process for preparing atazanavir bisulfate and novel forms
US20050256314A1 (en) *	2004-05-04	2005-11-17	Soojin Kim	Process employing controlled crystallization in forming crystals of a pharmaceutical
US20050288343A1 (en) *	2004-05-19	2005-12-29	Andrew Rusowicz	Process of preparing substituted carbamates and intermediates thereof
TWI415635B (zh) *	2004-05-28	2013-11-21	必治妥施貴寶公司	加衣錠片調製物及製備彼之方法
JP2008536888A (ja)	2005-04-19	2008-09-11	ニコメッドゲゼルシャフトミットベシュレンクテルハフツング	肺高血圧症の治療のためのロフルミラスト
MX2009013499A (es) *	2007-06-22	2010-01-18	Bristol Myers Squibb Co	Composiciones comprimidas que contienen atazanavir.
DE602008005316D1 (de) *	2007-06-22	2011-04-14	Bristol Myers Squibb Co	Tablettierte atazanavirhaltige zusammensetzungen
JP2010530892A (ja) *	2007-06-22	2010-09-16	ブリストル−マイヤーズスクイブカンパニー	アタザナビルを含む錠剤組成物
CN101778624A (zh) *	2007-06-22	2010-07-14	百时美施贵宝公司	含有阿扎那韦的压片组合物
KR20100110804A (ko)	2007-11-30	2010-10-13	와이어쓰 엘엘씨	포스포디에스테라제 10의 저해물질로서의 아릴 및 헤테로아릴 융합된 이미다조[1,5-ａ]피라진
US20090143361A1 (en) *	2007-11-30	2009-06-04	Elbion Gmbh	Pyrido[3,2-E]Pyrazines, Process For Preparing The Same, And Their Use As Inhibitors Of Phosphodiesterase 10
CA2756810A1 (en)	2009-03-31	2010-10-07	Arqule, Inc.	Pyrazolo-pyrrolopyridine-dione derivatives useful in the treatment of cancer
CN103547580B (zh) *	2011-03-22	2016-12-07	阿迪维纳斯疗法有限公司	取代的稠合三环化合物、其组合物及医药用途
EP3138830A4 (en) *	2014-04-30	2018-05-30	Air Water Inc.	Composition containing 3-chloro-4-methoxybenzylamine hydrochloride, and method for producing same
WO2017168174A1 (en)	2016-04-02	2017-10-05	N4 Pharma Uk Limited	New pharmaceutical forms of sildenafil
WO2018002673A1 (en)	2016-07-01	2018-01-04	N4 Pharma Uk Limited	Novel formulations of angiotensin ii receptor antagonists
CN108395377A (zh) *	2018-01-16	2018-08-14	吴江信凯医药科技有限公司	一种3-氯-4-甲氧基苄胺盐酸盐的制备方法
US11618751B1 (en)	2022-03-25	2023-04-04	Ventus Therapeutics U.S., Inc.	Pyrido-[3,4-d]pyridazine amine derivatives useful as NLRP3 derivatives
US11319319B1 (en)	2021-04-07	2022-05-03	Ventus Therapeutics U.S., Inc.	Compounds for inhibiting NLRP3 and uses thereof
US12331048B2 (en)	2022-10-31	2025-06-17	Ventus Therapeutics U.S., Inc.	Pyrido-[3,4-d]pyridazine amine derivatives useful as NLRP3 inhibitors
EP4727541A2 (en) *	2023-06-16	2026-04-22	Plexium, Inc.	Compounds and pharmaceutical compositions that degrade swi/snf-related matrix-associated actin-dependent regulator of chromatin subfamily a

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3669950A (en)	1970-12-01	1972-06-13	Squibb & Sons Inc	DIPYRAZOLO{8 3,4-b:3,4d{9 -PYRIDIN-3-ONES
US3787430A (en)	1972-07-13	1974-01-22	Squibb & Sons Inc	Derivatives of dipyrazolo(3,4-b;3',4'-d)pyridines
US4072681A (en)	1977-03-02	1978-02-07	E. R. Squibb & Sons, Inc.	3,7-Dihydro- and 1,7-dihydro-4H-pyrazolo[4',3':5,6]pyrido[4,3-d]pyrimidin-4-ones
US5055465A (en) *	1989-05-31	1991-10-08	Berlex Laboratories, Inc.	Imidazoquinoxalinones, their aza analogs and process for their preparation
US5250534A (en)	1990-06-20	1993-10-05	Pfizer Inc.	Pyrazolopyrimidinone antianginal agents
CA2056142A1 (en)	1990-11-27	1992-05-28	Hirotomo Masuya	Pyridopyridazine compounds and their use
JP3477651B2 (ja) *	1993-01-28	2003-12-10	武田薬品工業株式会社	スーパーオキシドラジカルの検出・定量法
GB9311920D0 (en)	1993-06-09	1993-07-28	Pfizer Ltd	Therapeutic agents
JP3919835B2 (ja) *	1994-08-09	2007-05-30	エーザイ・アール・アンド・ディー・マネジメント株式会社	縮合ピリダジン系化合物
DE69533057T2 (de) *	1994-08-09	2005-06-16	Eisai Co., Ltd.	Kondensierte pyridazinverbindungen
JPH08143558A (ja) *	1994-11-21	1996-06-04	Fujisawa Pharmaceut Co Ltd	アミノピペラジン誘導体の新規医薬用途
GB9423910D0 (en) *	1994-11-26	1995-01-11	Pfizer Ltd	Therapeutic agents
US5488055A (en) *	1995-03-10	1996-01-30	Sanofi Winthrop Inc.	Substituted N-cycloalkylmethyl-1H-pyrazolo(3,4-b)quinolin-4 amines and compositions and methods of use thereof
US5614530A (en) *	1995-03-10	1997-03-25	Sterling Winthrop Inc.	Substituted N-arylmethyl and heterocyclmethyl-1H-pyrazolo[3,4-b]quinolin-4-amines and compositions and methods of use thereof
JPH10114657A (ja) *	1996-08-20	1998-05-06	Eisai Co Ltd	縮合ピリダジン系化合物の勃起機能不全症治療剤
CN1121220C (zh) *	1996-08-20	2003-09-17	卫材株式会社	稠合哒嗪系化合物的勃起机能不全症治疗剂
US5874437A (en)	1996-11-01	1999-02-23	Nitromed, Inc.	Nitrosated and nitrosylated phosphodiesterase inhibitor compounds, compositions and their uses
AU7553198A (en) *	1997-06-12	1998-12-30	Sumitomo Pharmaceuticals Company, Limited	Pyrazole derivatives
US6087368A (en)	1998-06-08	2000-07-11	Bristol-Myers Squibb Company	Quinazolinone inhibitors of cGMP phosphodiesterase
US6326379B1 (en) *	1998-09-16	2001-12-04	Bristol-Myers Squibb Co.	Fused pyridine inhibitors of cGMP phosphodiesterase

2000
- 2000-03-09 AU AU37327/00A patent/AU765128B2/en not_active Ceased
- 2000-03-09 KR KR1020017012014A patent/KR20020015030A/ko not_active Withdrawn
- 2000-03-09 WO PCT/US2000/006100 patent/WO2000056719A1/en not_active Ceased
- 2000-03-09 ID IDW00200102056A patent/ID30182A/id unknown
- 2000-03-09 JP JP2000606580A patent/JP2002540102A/ja active Pending
- 2000-03-09 CA CA002368023A patent/CA2368023A1/en not_active Abandoned
- 2000-03-09 EP EP00916180A patent/EP1165521A4/en not_active Withdrawn
- 2000-03-09 CN CNB008053766A patent/CN1161341C/zh not_active Expired - Fee Related
- 2000-03-15 US US09/526,162 patent/US6316438B1/en not_active Expired - Lifetime
- 2000-03-22 UY UY26071A patent/UY26071A1/es not_active Application Discontinuation

Also Published As

Publication number	Publication date
UY26071A1 (es)	2000-10-31
CN1344257A (zh)	2002-04-10
AU765128B2 (en)	2003-09-11
AU3732700A (en)	2000-10-09
US6316438B1 (en)	2001-11-13
EP1165521A4 (en)	2002-05-22
WO2000056719A1 (en)	2000-09-28
EP1165521A1 (en)	2002-01-02
CA2368023A1 (en)	2000-09-28
CN1161341C (zh)	2004-08-11
KR20020015030A (ko)	2002-02-27
JP2002540102A (ja)	2002-11-26

Publication	Publication Date	Title
ID30182A (id)	2001-11-08	PENGHAMBAT-PENGHAMBAT PIRIDOPIRIDAZINA LEBURAN DARI cGMP FOSFODIESTERASE
DE60131504D1 (de)	2008-01-03	Scheinwerfer
DE60207669D1 (de)	2006-01-05	Scheinwerfer
FI20002430A0 (fi)	2000-11-06	Valkoinen valaisu
DE60033639D1 (de)	2007-04-12	Leuchte
DE50101409D1 (de)	2004-03-04	Reflektor
DE50015977D1 (de)	2010-10-07	Beleuchtungsanordnung
DE60116905D1 (de)	2006-04-13	Beleuchtungsvorrichtungen
DE60100269D1 (de)	2003-06-18	Scheinwerfer
DE50111451D1 (de)	2006-12-28	Flache Beleuchtungseinheit
DE60201107D1 (de)	2004-10-07	Scheinwerfer
ATE296344T1 (de)	2005-06-15	Kerzenzusammensetzung
DE60132866D1 (de)	2008-04-03	Scheinwerfer
DE60037965D1 (de)	2008-03-20	Leuchte
FI20002186L (fi)	2002-04-05	Valaisinjärjestely
DE60042515D1 (de)	2009-08-20	Glühlampe
DE60227466D1 (de)	2008-08-21	Scheinwerfer
DE29908139U8 (de)	2007-09-20	Beleuchtungsanordnung
DE60005106D1 (de)	2003-10-16	Kerze
FR2800153B1 (fr)	2002-01-04	Luminaire antivandalisme
FI4506U1 (fi)	2000-07-20	Kohdevalaisin
NO990005D0 (no)	1999-01-04	Lysestake
SK3051U (sk)	2001-12-03	Svietnik
UA4732S (uk)	2001-04-16	Свічник
FI3955U1 (fi)	1999-05-19	Lyhty