IE32006L - 1 - ethyl - 2 - aminomethyl - pyrrolidine isomers - Google Patents

1 - ethyl - 2 - aminomethyl - pyrrolidine isomers

Info

Publication number
IE32006L
IE32006L IE680395A IE39568A IE32006L IE 32006 L IE32006 L IE 32006L IE 680395 A IE680395 A IE 680395A IE 39568 A IE39568 A IE 39568A IE 32006 L IE32006 L IE 32006L
Authority
IE
Ireland
Prior art keywords
pyrrolidine
aminomethyl
ethyl
tartrate
isomers
Prior art date
Application number
IE680395A
Other versions
IE32006B1 (en
Original Assignee
Ile De France
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ile De France filed Critical Ile De France
Publication of IE32006L publication Critical patent/IE32006L/en
Publication of IE32006B1 publication Critical patent/IE32006B1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/08—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon radicals, substituted by hetero atoms, attached to ring carbon atoms
    • C07D207/09—Radicals substituted by nitrogen atoms, not forming part of a nitro radical

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pyrrole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

1,207,752. Optical isomers of 1 - ethyl - 2 - aminomethyl - pyrrolidine. SOC. D'ETUDES SCIENTIFIQUES ET INDUSTRILLES DE L'ILE - DE - FRANCE. 22 April, 1968 [24 April, 1967], No. 18932/68. Heading C2C. The levorotatory and dextrorotatory isomers of 1 - ethyl - 2 - aminomethyl - pyrrolidine are separated by a process comprising forming a tartrate salt of a mixture of said isomers with an optically active tartaric acid and separating an optically active tartrate salt by crystallization. It is preferred to treat the pyrrolidine first with d - tartaric acid which leads to crystallization of the d-tartrate of dextrorotatory 1 - ethyl - 2 - aminomethyl - pyrrolidine. The crystals are removed by filtration and the optically active amine may be liberated conventionally from the tartrate. The filtrate is then rendered alkaline and treated with I - tartaric acid to yield the l - tartrate of l - 1 - amino - 2 - aminomethyl - pyrrolidine in the crystalline state. If desired, the method of treatment may be reversed. (From GB1207752 A) [FR1528014A]
IE395/68A 1967-04-24 1968-04-05 Process for the preparation of the optical isomers of 1-ethyl-2-aminomethylpyrrolidine IE32006B1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR104008A FR1528014A (en) 1967-04-24 1967-04-24 Process for the preparation of optical isomers of ethyl-1, aminomethyl-2-pyrrolidine

Publications (2)

Publication Number Publication Date
IE32006L true IE32006L (en) 1968-10-24
IE32006B1 IE32006B1 (en) 1973-03-07

Family

ID=8629548

Family Applications (1)

Application Number Title Priority Date Filing Date
IE395/68A IE32006B1 (en) 1967-04-24 1968-04-05 Process for the preparation of the optical isomers of 1-ethyl-2-aminomethylpyrrolidine

Country Status (19)

Country Link
AT (1) AT278771B (en)
BE (1) BE712925A (en)
BR (1) BR6898525D0 (en)
CH (1) CH484899A (en)
CS (1) CS153010B2 (en)
DE (1) DE1795712A1 (en)
DK (1) DK129285B (en)
ES (1) ES352901A1 (en)
FR (1) FR1528014A (en)
GB (1) GB1207752A (en)
IE (1) IE32006B1 (en)
IL (1) IL29781A (en)
IT (1) IT954025B (en)
MC (1) MC715A1 (en)
NL (1) NL6805746A (en)
OA (1) OA02787A (en)
PL (1) PL72570B1 (en)
SE (1) SE323375B (en)
YU (1) YU32376B (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL52645A (en) * 1976-08-05 1980-02-29 Synthelabo Optically active 1 substituted 2 aminomethyl pyrrolidines stereospecifics synthesis thereof and process for the preparation of optically active 2 methoxy n pyrrolidylmethyl benzamides
SE447991B (en) * 1982-09-30 1987-01-12 Astra Pharma Prod DIASTEREOMERS OF DI-P-TOLUOYL TARTRATE WITH 1-ETHYL-2-AMINOMETHYLPYRROLIDINE AND PROCEDURE FOR PREPARING THESE
DE4425070A1 (en) * 1994-07-15 1996-01-18 Degussa Process for the preparation of optically active l-substituted 2- (aminomethyl) pyrrolidines

Also Published As

Publication number Publication date
DK129285B (en) 1974-09-23
FR1528014A (en) 1968-06-07
DK129285C (en) 1975-02-10
CH484899A (en) 1970-01-31
BR6898525D0 (en) 1973-05-10
IE32006B1 (en) 1973-03-07
IL29781A0 (en) 1968-06-20
NL6805746A (en) 1968-10-25
YU93968A (en) 1974-04-30
MC715A1 (en) 1969-02-05
OA02787A (en) 1970-12-15
YU32376B (en) 1974-10-31
AT278771B (en) 1970-02-10
IT954025B (en) 1973-08-30
IL29781A (en) 1971-08-25
CS153010B2 (en) 1974-02-22
GB1207752A (en) 1970-10-07
ES352901A1 (en) 1969-09-01
BE712925A (en) 1968-09-30
PL72570B1 (en) 1974-08-30
DE1795712A1 (en) 1973-10-18
SE323375B (en) 1970-05-04

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