IE32359L - Antibacterial composition - Google Patents
Antibacterial compositionInfo
- Publication number
- IE32359L IE32359L IE109368A IE109368A IE32359L IE 32359 L IE32359 L IE 32359L IE 109368 A IE109368 A IE 109368A IE 109368 A IE109368 A IE 109368A IE 32359 L IE32359 L IE 32359L
- Authority
- IE
- Ireland
- Prior art keywords
- hetacillin
- ampicillin
- agents
- composition
- amphotericin
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title abstract 4
- 230000000844 anti-bacterial effect Effects 0.000 title abstract 2
- 229960000723 ampicillin Drugs 0.000 abstract 3
- AVKUERGKIZMTKX-NJBDSQKTSA-N ampicillin Chemical compound C1([C@@H](N)C(=O)N[C@H]2[C@H]3SC([C@@H](N3C2=O)C(O)=O)(C)C)=CC=CC=C1 AVKUERGKIZMTKX-NJBDSQKTSA-N 0.000 abstract 3
- 229960003884 hetacillin Drugs 0.000 abstract 3
- DXVUYOAEDJXBPY-NFFDBFGFSA-N hetacillin Chemical compound C1([C@@H]2C(=O)N(C(N2)(C)C)[C@H]2[C@H]3SC([C@@H](N3C2=O)C(O)=O)(C)C)=CC=CC=C1 DXVUYOAEDJXBPY-NFFDBFGFSA-N 0.000 abstract 3
- APKFDSVGJQXUKY-KKGHZKTASA-N Amphotericin-B Natural products O[C@H]1[C@@H](N)[C@H](O)[C@@H](C)O[C@H]1O[C@H]1C=CC=CC=CC=CC=CC=CC=C[C@H](C)[C@@H](O)[C@@H](C)[C@H](C)OC(=O)C[C@H](O)C[C@H](O)CC[C@@H](O)[C@H](O)C[C@H](O)C[C@](O)(C[C@H](O)[C@H]2C(O)=O)O[C@H]2C1 APKFDSVGJQXUKY-KKGHZKTASA-N 0.000 abstract 2
- APKFDSVGJQXUKY-INPOYWNPSA-N amphotericin B Chemical compound O[C@H]1[C@@H](N)[C@H](O)[C@@H](C)O[C@H]1O[C@H]1/C=C/C=C/C=C/C=C/C=C/C=C/C=C/[C@H](C)[C@@H](O)[C@@H](C)[C@H](C)OC(=O)C[C@H](O)C[C@H](O)CC[C@@H](O)[C@H](O)C[C@H](O)C[C@](O)(C[C@H](O)[C@H]2C(O)=O)O[C@H]2C1 APKFDSVGJQXUKY-INPOYWNPSA-N 0.000 abstract 2
- 229960003942 amphotericin b Drugs 0.000 abstract 2
- 208000035143 Bacterial infection Diseases 0.000 abstract 1
- 239000004150 EU approved colour Substances 0.000 abstract 1
- 239000003963 antioxidant agent Substances 0.000 abstract 1
- 235000006708 antioxidants Nutrition 0.000 abstract 1
- 208000022362 bacterial infectious disease Diseases 0.000 abstract 1
- 238000004040 coloring Methods 0.000 abstract 1
- 239000000796 flavoring agent Substances 0.000 abstract 1
- 235000013355 food flavoring agent Nutrition 0.000 abstract 1
- 235000003599 food sweetener Nutrition 0.000 abstract 1
- 239000003755 preservative agent Substances 0.000 abstract 1
- 239000003352 sequestering agent Substances 0.000 abstract 1
- 239000000375 suspending agent Substances 0.000 abstract 1
- 239000003765 sweetening agent Substances 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/429—Thiazoles condensed with heterocyclic ring systems
- A61K31/43—Compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula, e.g. penicillins, penems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Molecular Biology (AREA)
- Saccharide Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
1,244,024. Antibacterial compositions. BRISTOL-MYERS CO. 19 Sept., 1968 [20 Sept., 1967], No. 44519/68. Heading A5B. A composition for treating bacterial infection comprises 15-110 parts by weight of amphotericin B to 100-550 parts by weight of ampicillin or hetacillin. A preferred dosage unit comprises 15-110 mg. of amphotericin B per unit dose and 100-550 mg. of hetacillin or ampicillin per unit dose. Preferably the composition is reconstituted with water for use, and contains a buffer to maintain the pH at 2-8 (preferably 2-3 with hetacillin; 5-8 with ampicillin). Conventional sequestering agents, suspending agents, sweetening agents, colouring and flavouring agents, anti-oxidants or preservatives may be included (many examples given).
[GB1244024A]
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US66930067A | 1967-09-20 | 1967-09-20 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IE32359L true IE32359L (en) | 1969-03-20 |
| IE32359B1 IE32359B1 (en) | 1973-07-11 |
Family
ID=24685859
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IE109368A IE32359B1 (en) | 1967-09-20 | 1968-09-11 | Antibacterial compositions |
Country Status (2)
| Country | Link |
|---|---|
| GB (1) | GB1244024A (en) |
| IE (1) | IE32359B1 (en) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL57906A0 (en) * | 1978-08-04 | 1979-11-30 | Beecham Group Ltd | Powder containing salts of certain penicillins for preparing orally administrable syrups |
| IL57907A0 (en) * | 1978-08-04 | 1979-11-30 | Beecham Group Ltd | Powder containing salts of certain penicillins for preparing orally administrable syrups |
-
1968
- 1968-09-11 IE IE109368A patent/IE32359B1/en unknown
- 1968-09-19 GB GB4451968A patent/GB1244024A/en not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| GB1244024A (en) | 1971-08-25 |
| IE32359B1 (en) | 1973-07-11 |
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