IE32479L - 3-indolinyl-2-amino-propionitriles - Google Patents
3-indolinyl-2-amino-propionitrilesInfo
- Publication number
- IE32479L IE32479L IE681320A IE132068A IE32479L IE 32479 L IE32479 L IE 32479L IE 681320 A IE681320 A IE 681320A IE 132068 A IE132068 A IE 132068A IE 32479 L IE32479 L IE 32479L
- Authority
- IE
- Ireland
- Prior art keywords
- radical
- unsubstituted
- substituted
- formula
- araliphatic hydrocarbon
- Prior art date
Links
- -1 hydrocarbon radical Chemical class 0.000 abstract 9
- 239000004215 Carbon black (E152) Substances 0.000 abstract 3
- 125000001931 aliphatic group Chemical group 0.000 abstract 3
- 229930195733 hydrocarbon Natural products 0.000 abstract 3
- 229910052739 hydrogen Inorganic materials 0.000 abstract 2
- 239000001257 hydrogen Substances 0.000 abstract 2
- 125000004435 hydrogen atom Chemical class [H]* 0.000 abstract 2
- JXDYKVIHCLTXOP-UHFFFAOYSA-N isatin Chemical compound C1=CC=C2C(=O)C(=O)NC2=C1 JXDYKVIHCLTXOP-UHFFFAOYSA-N 0.000 abstract 2
- PXHUCPJKTHEEPU-UHFFFAOYSA-N 2,3-dihydro-1h-indol-3-ol Chemical compound C1=CC=C2C(O)CNC2=C1 PXHUCPJKTHEEPU-UHFFFAOYSA-N 0.000 abstract 1
- 125000004442 acylamino group Chemical group 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 125000005083 alkoxyalkoxy group Chemical group 0.000 abstract 1
- 125000004453 alkoxycarbonyl group Chemical group 0.000 abstract 1
- 125000003282 alkyl amino group Chemical group 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 150000005840 aryl radicals Chemical class 0.000 abstract 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 1
- 125000002915 carbonyl group Chemical group [*:2]C([*:1])=O 0.000 abstract 1
- 125000004985 dialkyl amino alkyl group Chemical group 0.000 abstract 1
- 125000004663 dialkyl amino group Chemical group 0.000 abstract 1
- 125000001188 haloalkyl group Chemical group 0.000 abstract 1
- 125000005843 halogen group Chemical group 0.000 abstract 1
- 125000005842 heteroatom Chemical group 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 125000002768 hydroxyalkyl group Chemical group 0.000 abstract 1
- 239000003701 inert diluent Substances 0.000 abstract 1
- 239000012442 inert solvent Substances 0.000 abstract 1
- WOFDVDFSGLBFAC-UHFFFAOYSA-N lactonitrile Chemical compound CC(O)C#N WOFDVDFSGLBFAC-UHFFFAOYSA-N 0.000 abstract 1
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 abstract 1
- 229910052757 nitrogen Inorganic materials 0.000 abstract 1
- 125000004433 nitrogen atom Chemical group N* 0.000 abstract 1
- 150000003254 radicals Chemical class 0.000 abstract 1
- 239000000376 reactant Substances 0.000 abstract 1
- 150000003335 secondary amines Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
- C07D209/32—Oxygen atoms
- C07D209/38—Oxygen atoms in positions 2 and 3, e.g. isatin
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Indole Compounds (AREA)
Abstract
1,251,985. lndolinonyl-aminopropionitriles and their production. AGRIPAT S.A. 1 Nov., 1968 [3 Nov., 1967], No. 51787/68. Heading C2C. 3 - (3 - Hydroxy - indolin - 2<SP>1 </SP> - on - 3<SP>1 </SP> - yl) - 2- aminopropionitriles of the formula wherein R<SP>1</SP> represents an unsubstituted or substituted aliphatic or araliphatic hydrocarbon radical which may also be substituted by a heterocyclic radical, R<SP>2</SP> represents an unsubstituted or substituted aliphatic or araliphatic hydrocarbon radical which may also be substituted by a heterocyclic radical or a monocarbocyclic aryl radical, or R 1 and R 2 together with the adjacent nitrogen atom represent a 5- to 7-membered heterocyclic radical which may contain further hetero atoms as ring members, R 3 represents hydrogen, an unsubstituted or substituted aliphatic or araliphatic hydrocarbon radical having 1 to 8 carbon atoms, a piperidinoalkyl radical or an acyl radical and R 4 to R 7 independently of each other each represent hydrogen, a lower (up to C 8 ) alkyl, haloalkyl, hydroxyalkyl, dialkylaminoalkyl, alkoxy, alkoxyalkoxy, alkylamino, dialkylamino, acylamino, mono- or di-alkyl-carbamoyl, alkoxycarbonyl or acyloxy radicals, a halogen atom, or the hydroxyl, cyano, carbamoyl, carbonyl or nitro group, may be obtained by reacting an isatin of the formula with lactonitrile and with a secondary amine of the formula R 1 R 2 NH. The reaction is suitably carried out employing approximately equimolar amounts of the reactants at a temperature between 0‹ and 50‹ C., optionally in the presence of an inert diluent or solvent. Many examples of the products are given.
[GB1251985A]
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH1543667A CH487890A (en) | 1967-11-03 | 1967-11-03 | Process for the preparation of 3-indolinyl-2-aminopropionitriles |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IE32479L true IE32479L (en) | 1969-05-03 |
| IE32479B1 IE32479B1 (en) | 1973-08-22 |
Family
ID=4409082
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IE1320/68A IE32479B1 (en) | 1967-11-03 | 1968-11-01 | 3-indolinyl-2-amino-propionitriles and process for their production |
Country Status (14)
| Country | Link |
|---|---|
| AT (1) | AT281013B (en) |
| BE (1) | BE723271A (en) |
| BR (1) | BR6803678D0 (en) |
| CH (1) | CH487890A (en) |
| DE (1) | DE1806406A1 (en) |
| DK (1) | DK125201B (en) |
| ES (1) | ES359841A1 (en) |
| FR (1) | FR1588142A (en) |
| GB (1) | GB1251985A (en) |
| IE (1) | IE32479B1 (en) |
| IL (1) | IL30993A (en) |
| NL (1) | NL6815636A (en) |
| RO (1) | RO54404A (en) |
| SE (1) | SE334886B (en) |
-
1967
- 1967-11-03 CH CH1543667A patent/CH487890A/en not_active IP Right Cessation
-
1968
- 1968-10-30 SE SE14677/68A patent/SE334886B/xx unknown
- 1968-10-30 DK DK525868AA patent/DK125201B/en unknown
- 1968-10-31 FR FR1588142D patent/FR1588142A/fr not_active Expired
- 1968-10-31 RO RO58067A patent/RO54404A/ro unknown
- 1968-10-31 DE DE19681806406 patent/DE1806406A1/en active Pending
- 1968-10-31 BE BE723271D patent/BE723271A/xx unknown
- 1968-10-31 AT AT1062868A patent/AT281013B/en not_active IP Right Cessation
- 1968-11-01 NL NL6815636A patent/NL6815636A/xx unknown
- 1968-11-01 IE IE1320/68A patent/IE32479B1/en unknown
- 1968-11-01 BR BR203678/68A patent/BR6803678D0/en unknown
- 1968-11-01 IL IL30993A patent/IL30993A/en unknown
- 1968-11-01 GB GB1251985D patent/GB1251985A/en not_active Expired
- 1968-11-02 ES ES359841A patent/ES359841A1/en not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| IL30993A0 (en) | 1969-01-29 |
| BR6803678D0 (en) | 1973-01-02 |
| AT281013B (en) | 1970-05-11 |
| FR1588142A (en) | 1970-04-03 |
| DE1806406A1 (en) | 1970-02-05 |
| NL6815636A (en) | 1969-05-06 |
| DK125201B (en) | 1973-01-15 |
| CH487890A (en) | 1970-03-31 |
| SE334886B (en) | 1971-05-10 |
| RO54404A (en) | 1974-02-01 |
| ES359841A1 (en) | 1970-06-16 |
| GB1251985A (en) | 1971-11-03 |
| IE32479B1 (en) | 1973-08-22 |
| BE723271A (en) | 1969-04-30 |
| IL30993A (en) | 1972-12-29 |
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