IE32514B1 - Synthesis of adamantyl compounds - Google Patents
Synthesis of adamantyl compoundsInfo
- Publication number
- IE32514B1 IE32514B1 IE806/68A IE80668A IE32514B1 IE 32514 B1 IE32514 B1 IE 32514B1 IE 806/68 A IE806/68 A IE 806/68A IE 80668 A IE80668 A IE 80668A IE 32514 B1 IE32514 B1 IE 32514B1
- Authority
- IE
- Ireland
- Prior art keywords
- integer
- general formula
- adamantane
- group
- pharmaceutically acceptable
- Prior art date
Links
- 125000005073 adamantyl group Chemical group C12(CC3CC(CC(C1)C3)C2)* 0.000 title 1
- 230000015572 biosynthetic process Effects 0.000 title 1
- 238000003786 synthesis reaction Methods 0.000 title 1
- ORILYTVJVMAKLC-UHFFFAOYSA-N adamantane Chemical class C1C(C2)CC3CC1CC2C3 ORILYTVJVMAKLC-UHFFFAOYSA-N 0.000 abstract 4
- 125000004178 (C1-C4) alkyl group Chemical group 0.000 abstract 3
- 229940052761 dopaminergic adamantane derivative Drugs 0.000 abstract 3
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 3
- 239000002253 acid Substances 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- WKBOTKDWSSQWDR-UHFFFAOYSA-N Bromine atom Chemical compound [Br] WKBOTKDWSSQWDR-UHFFFAOYSA-N 0.000 abstract 1
- ZAMOUSCENKQFHK-UHFFFAOYSA-N Chlorine atom Chemical compound [Cl] ZAMOUSCENKQFHK-UHFFFAOYSA-N 0.000 abstract 1
- 239000004480 active ingredient Substances 0.000 abstract 1
- GDTBXPJZTBHREO-UHFFFAOYSA-N bromine Substances BrBr GDTBXPJZTBHREO-UHFFFAOYSA-N 0.000 abstract 1
- 229910052794 bromium Inorganic materials 0.000 abstract 1
- 239000003874 central nervous system depressant Substances 0.000 abstract 1
- 229910052801 chlorine Inorganic materials 0.000 abstract 1
- 239000000460 chlorine Substances 0.000 abstract 1
- 239000003937 drug carrier Substances 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 150000002440 hydroxy compounds Chemical class 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- PNDPGZBMCMUPRI-UHFFFAOYSA-N iodine Chemical compound II PNDPGZBMCMUPRI-UHFFFAOYSA-N 0.000 abstract 1
- 239000003158 myorelaxant agent Substances 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
- C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C07D295/088—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB32914/67A GB1235853A (en) | 1967-07-18 | 1967-07-18 | Synthesis of adamantyl compounds |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IE32514L IE32514L (en) | 1969-01-18 |
| IE32514B1 true IE32514B1 (en) | 1973-09-05 |
Family
ID=10345897
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IE806/68A IE32514B1 (en) | 1967-07-18 | 1968-07-05 | Synthesis of adamantyl compounds |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US3539630A (2) |
| BE (1) | BE718163A (2) |
| CH (1) | CH477386A (2) |
| DE (1) | DE1768969A1 (2) |
| ES (1) | ES356218A1 (2) |
| FR (1) | FR1602903A (2) |
| GB (1) | GB1235853A (2) |
| IE (1) | IE32514B1 (2) |
| NL (1) | NL6810092A (2) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2420510C2 (ru) * | 2009-08-17 | 2011-06-10 | Российская Федерация в лице Федерального Агентства по Науке и Инновациям (РОСНАУКА) | Способ получения 2-(адамант-1-илокси)этанола |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4036977A (en) * | 1974-09-19 | 1977-07-19 | The Upjohn Company | Polycyclophenylpyrrolidines, their compositions and use |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3270036A (en) * | 1965-10-07 | 1966-08-30 | Squibb & Sons Inc | Adamantylbiguanides |
-
1967
- 1967-07-18 GB GB32914/67A patent/GB1235853A/en not_active Expired
-
1968
- 1968-07-05 IE IE806/68A patent/IE32514B1/xx unknown
- 1968-07-11 US US743941A patent/US3539630A/en not_active Expired - Lifetime
- 1968-07-17 NL NL6810092A patent/NL6810092A/xx unknown
- 1968-07-17 FR FR1602903D patent/FR1602903A/fr not_active Expired
- 1968-07-17 ES ES356218A patent/ES356218A1/es not_active Expired
- 1968-07-17 CH CH1066068A patent/CH477386A/fr not_active IP Right Cessation
- 1968-07-17 BE BE718163D patent/BE718163A/xx unknown
- 1968-07-18 DE DE19681768969 patent/DE1768969A1/de active Pending
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2420510C2 (ru) * | 2009-08-17 | 2011-06-10 | Российская Федерация в лице Федерального Агентства по Науке и Инновациям (РОСНАУКА) | Способ получения 2-(адамант-1-илокси)этанола |
Also Published As
| Publication number | Publication date |
|---|---|
| IE32514L (en) | 1969-01-18 |
| US3539630A (en) | 1970-11-10 |
| GB1235853A (en) | 1971-06-16 |
| DE1768969A1 (de) | 1972-02-03 |
| CH477386A (fr) | 1969-08-31 |
| FR1602903A (2) | 1971-02-22 |
| ES356218A1 (es) | 1970-01-16 |
| BE718163A (2) | 1968-12-31 |
| NL6810092A (2) | 1969-01-21 |
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