IE32806L - Sustained release drug composition - Google Patents
Sustained release drug compositionInfo
- Publication number
- IE32806L IE32806L IE690649A IE64969A IE32806L IE 32806 L IE32806 L IE 32806L IE 690649 A IE690649 A IE 690649A IE 64969 A IE64969 A IE 64969A IE 32806 L IE32806 L IE 32806L
- Authority
- IE
- Ireland
- Prior art keywords
- sustained
- sucrose
- sustained release
- carboxy vinyl
- drug composition
- Prior art date
Links
- 239000003814 drug Substances 0.000 title abstract 5
- 229940079593 drug Drugs 0.000 title abstract 3
- 239000000203 mixture Substances 0.000 title abstract 3
- 238000013268 sustained release Methods 0.000 title abstract 3
- 239000012730 sustained-release form Substances 0.000 title abstract 3
- 229920002125 Sokalan® Polymers 0.000 abstract 3
- RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 abstract 2
- CZMRCDWAGMRECN-UGDNZRGBSA-N Sucrose Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 CZMRCDWAGMRECN-UGDNZRGBSA-N 0.000 abstract 2
- 229930006000 Sucrose Natural products 0.000 abstract 2
- 239000005720 sucrose Substances 0.000 abstract 2
- 125000003903 2-propenyl group Chemical group [H]C([*])([H])C([H])=C([H])[H] 0.000 abstract 1
- 239000002202 Polyethylene glycol Substances 0.000 abstract 1
- 230000003111 delayed effect Effects 0.000 abstract 1
- 239000004615 ingredient Substances 0.000 abstract 1
- 229920001223 polyethylene glycol Polymers 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
- A61K9/209—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/2031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Preparation (AREA)
Abstract
1,263,392. Sustained-release medicaments. AMERICAN HOME PRODUCTS CORP. 13 May, 1969 [21 May, 1968; 13 Feb., 1969], No. 24256/69. Heading A5B. A delayed or sustained-release medicament is made by mixing together a drug a carboxy vinyl polymer and polyethylene glycol (P.E.G.) and tableting this mixture together with conventional tablet ingredients. Suitable carboxy vinyl polymers are acrylic acid polymers crosslinked with 0.75 to 2% of a polyallyl ether of sucrose having an average of about 5.8 allyl groups per molecule of sucrose. Suitable P.E.G.'s are those of molecular weight 1000 to 20,000 especially 4000 to 6000. Reference is made to compositions containing numerous known drugs.
[GB1263392A]
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US73074268A | 1968-05-21 | 1968-05-21 | |
| US80082769A | 1969-02-13 | 1969-02-13 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IE32806L true IE32806L (en) | 1969-11-21 |
| IE32806B1 IE32806B1 (en) | 1973-12-12 |
Family
ID=27112101
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IE649/69A IE32806B1 (en) | 1968-05-21 | 1969-05-07 | Sustained release drug composition |
Country Status (13)
| Country | Link |
|---|---|
| BE (1) | BE733417A (en) |
| CA (1) | CA955526A (en) |
| DE (1) | DE1925919C3 (en) |
| DK (1) | DK122708B (en) |
| ES (1) | ES367431A1 (en) |
| FI (1) | FI50833C (en) |
| FR (1) | FR2035801B1 (en) |
| GB (1) | GB1263392A (en) |
| IE (1) | IE32806B1 (en) |
| IL (1) | IL32200A (en) |
| NL (1) | NL164200C (en) |
| PH (1) | PH10312A (en) |
| SE (1) | SE354184B (en) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NL8500724A (en) * | 1985-03-13 | 1986-10-01 | Univ Groningen | DEVICES FOR REGULAR RELEASE OF ACTIVE SUBSTANCES AND METHOD OF MANUFACTURE THEREOF |
| GB8518927D0 (en) * | 1985-07-26 | 1985-09-04 | Vincent Processes Ltd | Tablets |
| US5603955A (en) * | 1994-07-18 | 1997-02-18 | University Of Cincinnati | Enhanced loading of solutes into polymer gels |
| DE60034592T2 (en) * | 1999-10-21 | 2007-12-27 | Daiso Co., Ltd. | NETWORK BASED ON A POLYALYL ETHER COMPOUND |
| CN100534531C (en) * | 2001-11-13 | 2009-09-02 | 山之内制药技术股份有限公司 | Soluble drug delivery system |
| BRPI0611272A2 (en) * | 2005-05-03 | 2011-11-16 | Mutual Pharmaceutical Co | quinine formulations |
| CN117180213A (en) * | 2023-10-23 | 2023-12-08 | 湖南洞庭药业股份有限公司 | Oxazepam tablet composition and preparation and stabilization method thereof |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3039933A (en) * | 1957-10-07 | 1962-06-19 | Premo Pharmaceutical Lab Inc | Ethyl cellulose-polyethylene glycol tablet matrix |
| US3087860A (en) * | 1958-12-19 | 1963-04-30 | Abbott Lab | Method of prolonging release of drug from a precompressed solid carrier |
| NL128902C (en) * | 1960-06-06 | |||
| US3158538A (en) * | 1961-02-23 | 1964-11-24 | White Lab Inc | Antidiarrheal compositions and method of using |
| US3346449A (en) * | 1963-09-27 | 1967-10-10 | Hoffmann La Roche | d-methorphan compositions and methods of making same |
| GB1043872A (en) * | 1964-02-03 | 1966-09-28 | Wiggins & Co Ltd Berry | Improvements in and relating to electric heaters |
| NZ248552A (en) * | 1993-08-31 | 1996-09-25 | Ind Res Ltd | Electroplating power supply: switchable bridge rectifier with output rectified |
-
1969
- 1969-05-07 IE IE649/69A patent/IE32806B1/en unknown
- 1969-05-08 CA CA050,885A patent/CA955526A/en not_active Expired
- 1969-05-09 IL IL32200A patent/IL32200A/en unknown
- 1969-05-13 GB GB24256/69A patent/GB1263392A/en not_active Expired
- 1969-05-16 PH PH10347A patent/PH10312A/en unknown
- 1969-05-20 DK DK272969AA patent/DK122708B/en not_active IP Right Cessation
- 1969-05-20 ES ES367431A patent/ES367431A1/en not_active Expired
- 1969-05-21 SE SE07188/69A patent/SE354184B/xx unknown
- 1969-05-21 FI FI691537A patent/FI50833C/en active
- 1969-05-21 DE DE1925919A patent/DE1925919C3/en not_active Expired
- 1969-05-21 FR FR6916537A patent/FR2035801B1/fr not_active Expired
- 1969-05-21 NL NL6907794.A patent/NL164200C/en not_active IP Right Cessation
- 1969-05-21 BE BE733417D patent/BE733417A/xx not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| IL32200A (en) | 1973-10-25 |
| GB1263392A (en) | 1972-02-09 |
| DE1925919B2 (en) | 1979-11-08 |
| FI50833C (en) | 1976-08-10 |
| DE1925919A1 (en) | 1969-11-27 |
| IE32806B1 (en) | 1973-12-12 |
| NL164200B (en) | 1980-07-15 |
| DK122708B (en) | 1972-04-04 |
| FR2035801A1 (en) | 1970-12-24 |
| CA955526A (en) | 1974-10-01 |
| BE733417A (en) | 1969-11-21 |
| NL6907794A (en) | 1969-11-25 |
| NL164200C (en) | 1980-12-15 |
| ES367431A1 (en) | 1971-05-01 |
| PH10312A (en) | 1976-11-25 |
| FI50833B (en) | 1976-04-30 |
| IL32200A0 (en) | 1969-07-30 |
| SE354184B (en) | 1973-03-05 |
| FR2035801B1 (en) | 1974-08-30 |
| DE1925919C3 (en) | 1980-07-17 |
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