IE33603L - Modified allergenic material - Google Patents
Modified allergenic materialInfo
- Publication number
- IE33603L IE33603L IE143069A IE143069A IE33603L IE 33603 L IE33603 L IE 33603L IE 143069 A IE143069 A IE 143069A IE 143069 A IE143069 A IE 143069A IE 33603 L IE33603 L IE 33603L
- Authority
- IE
- Ireland
- Prior art keywords
- allergenic material
- haloformate
- oct
- modified
- chloroformate
- Prior art date
Links
- 230000002009 allergenic effect Effects 0.000 title abstract 7
- 239000000463 material Substances 0.000 title abstract 7
- 239000013566 allergen Substances 0.000 abstract 2
- 102000003886 Glycoproteins Human genes 0.000 abstract 1
- 108090000288 Glycoproteins Proteins 0.000 abstract 1
- 125000003342 alkenyl group Chemical group 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 125000003710 aryl alkyl group Chemical group 0.000 abstract 1
- 125000005129 aryl carbonyl group Chemical group 0.000 abstract 1
- 125000003118 aryl group Chemical group 0.000 abstract 1
- HUNKABVKDXZOTL-UHFFFAOYSA-N carbonochloridoyl benzoate Chemical compound ClC(=O)OC(=O)C1=CC=CC=C1 HUNKABVKDXZOTL-UHFFFAOYSA-N 0.000 abstract 1
- FZFAMSAMCHXGEF-UHFFFAOYSA-N chloro formate Chemical compound ClOC=O FZFAMSAMCHXGEF-UHFFFAOYSA-N 0.000 abstract 1
- 125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 125000005843 halogen group Chemical group 0.000 abstract 1
- 125000000623 heterocyclic group Chemical group 0.000 abstract 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
- 238000007911 parenteral administration Methods 0.000 abstract 1
- 239000000825 pharmaceutical preparation Substances 0.000 abstract 1
- 102000004169 proteins and genes Human genes 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/35—Allergens
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Medicinal Chemistry (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Abstract
1,243,832. Allergens. BEECHAM GROUP Ltd. 23 Oct., 1969 [25 Oct., 1968], No. 50645/ 68. Heading A5B. The allergenicity of an allergenic material is reduced by treating the allergenic material with a haloformate having the formula RO.CO.X wherein X is a halogen and R is alkyl, alkenyl, aryl, aralkyl, arylcarbonyl or a heterocyclic group, at a pH of from 1 to 7 and recovering the resultant modified allergenic material. The haloformate is preferably a chloroformate especially methyl, ethyl or benzoyl chloroformate. The temperature employed for the treatment is preferably about 20C. The allergenic material treated may be a protein or glycoprotein extract of the whole allergen. The allergenic material may be, or may be derived from, pollen. Pharmaceutical preparations for parenteral administration comprise the modified allergenic material and a parenterally acceptable carrier.
[GB1243832A]
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB5064568A GB1243832A (en) | 1968-10-25 | 1968-10-25 | Vaccines |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IE33603L true IE33603L (en) | 1970-04-25 |
| IE33603B1 IE33603B1 (en) | 1974-08-21 |
Family
ID=10456759
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IE143069A IE33603B1 (en) | 1968-10-25 | 1969-10-20 | Vaccines |
Country Status (10)
| Country | Link |
|---|---|
| AT (1) | AT293617B (en) |
| BE (1) | BE740801A (en) |
| CH (1) | CH536633A (en) |
| DE (1) | DE1953995A1 (en) |
| DK (1) | DK125308B (en) |
| ES (1) | ES372843A1 (en) |
| FR (1) | FR2021556B1 (en) |
| GB (1) | GB1243832A (en) |
| IE (1) | IE33603B1 (en) |
| NL (1) | NL6916121A (en) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2178582B1 (en) * | 2000-12-01 | 2003-11-01 | Lozano Juan Jose Martin | CUP PROFILE, FOR THE ASSEMBLY OF TWO FLOORS OF ELECTRIC PANELS. |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1174854A (en) * | 1967-07-07 | 1969-12-17 | Miles Lab | New Biologically Active Conjugates |
-
1968
- 1968-10-25 GB GB5064568A patent/GB1243832A/en not_active Expired
-
1969
- 1969-10-20 IE IE143069A patent/IE33603B1/en unknown
- 1969-10-23 DK DK561269A patent/DK125308B/en unknown
- 1969-10-23 FR FR6936324A patent/FR2021556B1/fr not_active Expired
- 1969-10-24 ES ES372843A patent/ES372843A1/en not_active Expired
- 1969-10-24 BE BE740801D patent/BE740801A/xx unknown
- 1969-10-24 NL NL6916121A patent/NL6916121A/xx unknown
- 1969-10-24 AT AT1003869A patent/AT293617B/en not_active IP Right Cessation
- 1969-10-25 CH CH1589469A patent/CH536633A/en not_active IP Right Cessation
- 1969-10-27 DE DE19691953995 patent/DE1953995A1/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| FR2021556A1 (en) | 1970-07-24 |
| GB1243832A (en) | 1971-08-25 |
| BE740801A (en) | 1970-04-24 |
| DE1953995A1 (en) | 1970-04-30 |
| ES372843A1 (en) | 1971-11-01 |
| DK125308B (en) | 1973-02-05 |
| FR2021556B1 (en) | 1973-01-12 |
| NL6916121A (en) | 1970-04-28 |
| AT293617B (en) | 1971-10-25 |
| IE33603B1 (en) | 1974-08-21 |
| CH536633A (en) | 1973-05-15 |
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