IE34144L - Amino acids - Google Patents
Amino acidsInfo
- Publication number
- IE34144L IE34144L IE700607A IE60770A IE34144L IE 34144 L IE34144 L IE 34144L IE 700607 A IE700607 A IE 700607A IE 60770 A IE60770 A IE 60770A IE 34144 L IE34144 L IE 34144L
- Authority
- IE
- Ireland
- Prior art keywords
- lower alkyl
- represents hydrogen
- formula
- hydroxy
- carbon atoms
- Prior art date
Links
- 150000001413 amino acids Chemical class 0.000 title 1
- 125000000217 alkyl group Chemical group 0.000 abstract 5
- 125000002252 acyl group Chemical group 0.000 abstract 4
- 229910052739 hydrogen Inorganic materials 0.000 abstract 4
- 239000001257 hydrogen Substances 0.000 abstract 4
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 3
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 2
- 125000003545 alkoxy group Chemical group 0.000 abstract 2
- 125000004432 carbon atom Chemical group C* 0.000 abstract 2
- 150000002431 hydrogen Chemical class 0.000 abstract 2
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 2
- 101000653791 Bos taurus Protein S100-A12 Proteins 0.000 abstract 1
- 238000005727 Friedel-Crafts reaction Methods 0.000 abstract 1
- ISWSIDIOOBJBQZ-UHFFFAOYSA-N Phenol Chemical compound OC1=CC=CC=C1 ISWSIDIOOBJBQZ-UHFFFAOYSA-N 0.000 abstract 1
- 230000010933 acylation Effects 0.000 abstract 1
- 238000005917 acylation reaction Methods 0.000 abstract 1
- 125000004423 acyloxy group Chemical group 0.000 abstract 1
- 125000003435 aroyl group Chemical group 0.000 abstract 1
- 239000003054 catalyst Substances 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 230000003301 hydrolyzing effect Effects 0.000 abstract 1
- 239000000543 intermediate Substances 0.000 abstract 1
- 230000008707 rearrangement Effects 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 125000001424 substituent group Chemical group 0.000 abstract 1
- LMBFAGIMSUYTBN-MPZNNTNKSA-N teixobactin Chemical compound C([C@H](C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@H](CCC(N)=O)C(=O)N[C@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@H]1C(N[C@@H](C)C(=O)N[C@@H](C[C@@H]2NC(=N)NC2)C(=O)N[C@H](C(=O)O[C@H]1C)[C@@H](C)CC)=O)NC)C1=CC=CC=C1 LMBFAGIMSUYTBN-MPZNNTNKSA-N 0.000 abstract 1
- OUYCCCASQSFEME-UHFFFAOYSA-N tyrosine Natural products OC(=O)C(N)CC1=CC=C(O)C=C1 OUYCCCASQSFEME-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C227/14—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from compounds containing already amino and carboxyl groups or derivatives thereof
- C07C227/16—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from compounds containing already amino and carboxyl groups or derivatives thereof by reactions not involving the amino or carboxyl groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
1283802 Acyl derivatives of tyrosine F HOFFMANN-LA ROCHE & CO AG 12 May 1970 [14 May 1969] 22806/70 Heading C2C Compounds of formula wherein R<SP>1</SP> represents hydrogen, hydroxy, lower alkoxy, lower alkyl, halogen or amino, n stands for 1, 2 or 3, R<SP>2</SP> represents hydrogen or lower alkyl, R<SP>3</SP> represents hydroxy, lower alkoxy or mono- or di-(lower alkyl)-substituted amino, R<SP>4</SP> represents hydrogen, lower alkyl, lower alkanoyl or aroyl and R<SP>5</SP> represents hydrogen or lower alkyl and wherein one of the substituents R<SP>6</SP> and R<SP>7</SP> represents hydroxy and the other represents lower alkanoyl with at least two carbon atoms, where lower indicates that group contains up to 6 carbon atoms, and salts thereof are prepared by rearrangement of a compound of Formula II wherein one of R 6 # and R 7 # is H and the other is acyloxy by treatment with either a Friedel- Crafts catalyst or U.V. light of 250-350 nm. and optionally hydrolysing, resolving and/or salifying any product. Intermediates of Formula II above where R<SP>4</SP> is acyl are prepared by acylation of the corresponding phenol.
[GB1283802A]
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH735069A CH521311A (en) | 1969-05-14 | 1969-05-14 | Process for the preparation of phenylalamine derivatives |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IE34144L true IE34144L (en) | 1970-11-14 |
| IE34144B1 IE34144B1 (en) | 1975-02-19 |
Family
ID=4323751
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IE607/70A IE34144B1 (en) | 1969-05-14 | 1970-05-11 | A process for the manufacture of amino acids and derivatives thereof |
Country Status (13)
| Country | Link |
|---|---|
| JP (1) | JPS5144939B1 (en) |
| AT (1) | AT300767B (en) |
| BE (1) | BE750207A (en) |
| BR (1) | BR7018940D0 (en) |
| CH (1) | CH521311A (en) |
| ES (1) | ES379617A1 (en) |
| FR (1) | FR2047696A5 (en) |
| GB (1) | GB1283802A (en) |
| HU (1) | HU163707B (en) |
| IE (1) | IE34144B1 (en) |
| IL (1) | IL34503A (en) |
| NL (1) | NL144594B (en) |
| SU (1) | SU366603A3 (en) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4271187A (en) * | 1978-06-05 | 1981-06-02 | Merck & Co., Inc. | Substituted phenyl alanine antihypertensive agents |
-
1969
- 1969-05-14 CH CH735069A patent/CH521311A/en not_active IP Right Cessation
-
1970
- 1970-03-12 BR BR218940/70A patent/BR7018940D0/en unknown
- 1970-05-10 IL IL34503A patent/IL34503A/en unknown
- 1970-05-11 BE BE750207D patent/BE750207A/en unknown
- 1970-05-11 IE IE607/70A patent/IE34144B1/en unknown
- 1970-05-12 NL NL707006844A patent/NL144594B/en not_active IP Right Cessation
- 1970-05-12 GB GB22806/70A patent/GB1283802A/en not_active Expired
- 1970-05-12 SU SU1437526A patent/SU366603A3/ru active
- 1970-05-13 FR FR7017386A patent/FR2047696A5/fr not_active Expired
- 1970-05-13 ES ES379617A patent/ES379617A1/en not_active Expired
- 1970-05-13 HU HUHO1295A patent/HU163707B/hu unknown
- 1970-05-13 AT AT430670A patent/AT300767B/en not_active IP Right Cessation
- 1970-05-14 JP JP45040576A patent/JPS5144939B1/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| IL34503A0 (en) | 1970-07-19 |
| IL34503A (en) | 1974-06-30 |
| GB1283802A (en) | 1972-08-02 |
| NL144594B (en) | 1975-01-15 |
| AT300767B (en) | 1972-08-10 |
| FR2047696A5 (en) | 1971-03-12 |
| CH521311A (en) | 1972-04-15 |
| SU366603A3 (en) | 1973-01-16 |
| BE750207A (en) | 1970-11-12 |
| JPS5144939B1 (en) | 1976-12-01 |
| NL7006844A (en) | 1970-11-17 |
| DE2023459B2 (en) | 1977-06-08 |
| IE34144B1 (en) | 1975-02-19 |
| BR7018940D0 (en) | 1973-03-13 |
| ES379617A1 (en) | 1973-01-16 |
| HU163707B (en) | 1973-10-27 |
| DE2023459A1 (en) | 1970-11-19 |
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