IE34216B1 - Pharmaceutically useful benzomorphanes and their production - Google Patents

Pharmaceutically useful benzomorphanes and their production

Info

Publication number: IE34216B1
Authority: IE; Ireland
Prior art keywords: compound; formula; converted; compounds; product
Prior art date: 1969-05-17

Application number

IE629/70A

Other languages

English (en)

Other versions

IE34216L (en

Original Assignee

Bayer Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1969-05-17

Filing date

1970-05-13

Publication date

1975-03-05

1970-05-13 Application filed by Bayer Ag filed Critical Bayer Ag

1970-11-17 Publication of IE34216L publication Critical patent/IE34216L/xx

1975-03-05 Publication of IE34216B1 publication Critical patent/IE34216B1/xx

Links

150000001875 compounds Chemical class 0.000 abstract 11
150000002148 esters Chemical class 0.000 abstract 3
150000003839 salts Chemical class 0.000 abstract 3
229920006395 saturated elastomer Polymers 0.000 abstract 3
239000004215 Carbon black (E152) Substances 0.000 abstract 2
239000002253 acid Substances 0.000 abstract 2
125000000217 alkyl group Chemical group 0.000 abstract 2
229930195733 hydrocarbon Natural products 0.000 abstract 2
239000002184 metal Substances 0.000 abstract 2
238000000034 method Methods 0.000 abstract 2
125000004433 nitrogen atom Chemical group N* 0.000 abstract 2
229930195734 saturated hydrocarbon Natural products 0.000 abstract 2
229930195735 unsaturated hydrocarbon Natural products 0.000 abstract 2
XFXPMWWXUTWYJX-UHFFFAOYSA-N Cyanide Chemical compound N#[C-] XFXPMWWXUTWYJX-UHFFFAOYSA-N 0.000 abstract 1
IYXGSMUGOJNHAZ-UHFFFAOYSA-N Ethyl malonate Chemical compound CCOC(=O)CC(=O)OCC IYXGSMUGOJNHAZ-UHFFFAOYSA-N 0.000 abstract 1
125000002252 acyl group Chemical group 0.000 abstract 1
230000010933 acylation Effects 0.000 abstract 1
238000005917 acylation reaction Methods 0.000 abstract 1
125000003545 alkoxy group Chemical group 0.000 abstract 1
230000000202 analgesic effect Effects 0.000 abstract 1
239000011230 binding agent Substances 0.000 abstract 1
125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 1
125000002057 carboxymethyl group Chemical group [H]OC(=O)C([H])([H])[*] 0.000 abstract 1
238000006243 chemical reaction Methods 0.000 abstract 1
239000003795 chemical substances by application Substances 0.000 abstract 1
125000001995 cyclobutyl group Chemical group [H]C1([H])C([H])([H])C([H])(*)C1([H])[H] 0.000 abstract 1
125000001559 cyclopropyl group Chemical group [H]C1([H])C([H])([H])C1([H])* 0.000 abstract 1
125000004186 cyclopropylmethyl group Chemical group [H]C([H])(*)C1([H])C([H])([H])C1([H])[H] 0.000 abstract 1
238000006114 decarboxylation reaction Methods 0.000 abstract 1
239000003085 diluting agent Substances 0.000 abstract 1
150000004820 halides Chemical class 0.000 abstract 1
125000005843 halogen group Chemical group 0.000 abstract 1
125000000623 heterocyclic group Chemical group 0.000 abstract 1
125000001183 hydrocarbyl group Chemical group 0.000 abstract 1
230000007062 hydrolysis Effects 0.000 abstract 1
238000006460 hydrolysis reaction Methods 0.000 abstract 1
125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
239000007788 liquid Substances 0.000 abstract 1
230000004048 modification Effects 0.000 abstract 1
238000012986 modification Methods 0.000 abstract 1
125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 abstract 1
238000007911 parenteral administration Methods 0.000 abstract 1
239000008194 pharmaceutical composition Substances 0.000 abstract 1
125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
238000007127 saponification reaction Methods 0.000 abstract 1
239000007787 solid Substances 0.000 abstract 1
JOXIMZWYDAKGHI-UHFFFAOYSA-N toluene-4-sulfonic acid Chemical compound CC1=CC=C(S(O)(=O)=O)C=C1 JOXIMZWYDAKGHI-UHFFFAOYSA-N 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
- C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
- C07D221/22—Bridged ring systems
- C07D221/26—Benzomorphans

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

IE629/70A 1969-05-17 1970-05-13 Pharmaceutically useful benzomorphanes and their production IE34216B1 (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
DE19691925297 DE1925297A1 (de)	1969-05-17	1969-05-17	Benzomorphanderivate

Publications (2)

Publication Number	Publication Date
IE34216L IE34216L (en)	1970-11-17
IE34216B1 true IE34216B1 (en)	1975-03-05

Family

ID=5734493

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IE629/70A IE34216B1 (en)	1969-05-17	1970-05-13	Pharmaceutically useful benzomorphanes and their production

Country Status (13)

Country	Link
AT (1)	AT313486B (de)
BE (1)	BE750486A (de)
BR (1)	BR6915372D0 (de)
CH (1)	CH546763A (de)
DE (1)	DE1925297A1 (de)
ES (1)	ES379711A1 (de)
FR (1)	FR2051540B1 (de)
GB (1)	GB1316301A (de)
HU (1)	HU166538B (de)
IE (1)	IE34216B1 (de)
IL (1)	IL34472A0 (de)
LU (1)	LU60867A1 (de)
NL (1)	NL7007142A (de)

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3345373A (en) *	1964-05-25	1967-10-03	Smith Kline French Lab	2-polymethylallyl-5, 9-dimethyl-6, 7-benzmorphans and derivatives

1969
- 1969-05-17 DE DE19691925297 patent/DE1925297A1/de active Pending
- 1969-12-19 BR BR215372/69A patent/BR6915372D0/pt unknown
1970
- 1970-05-05 IL IL34472A patent/IL34472A0/xx unknown
- 1970-05-06 LU LU60867D patent/LU60867A1/xx unknown
- 1970-05-06 CH CH683070A patent/CH546763A/de not_active IP Right Cessation
- 1970-05-13 IE IE629/70A patent/IE34216B1/xx unknown
- 1970-05-13 GB GB2321370A patent/GB1316301A/en not_active Expired
- 1970-05-14 AT AT417672A patent/AT313486B/de active
- 1970-05-15 FR FR7017982A patent/FR2051540B1/fr not_active Expired
- 1970-05-15 NL NL7007142A patent/NL7007142A/xx unknown
- 1970-05-15 BE BE750486D patent/BE750486A/xx unknown
- 1970-05-15 HU HUBA2412A patent/HU166538B/hu unknown
- 1970-05-16 ES ES379711A patent/ES379711A1/es not_active Expired

Also Published As

Publication number	Publication date
ES379711A1 (es)	1973-06-16
FR2051540A1 (de)	1971-04-09
GB1316301A (en)	1973-05-09
FR2051540B1 (de)	1974-08-09
HU166538B (de)	1975-04-28
IE34216L (en)	1970-11-17
DE1925297A1 (de)	1970-11-19
BR6915372D0 (pt)	1973-01-16
CH546763A (de)	1974-03-15
LU60867A1 (de)	1970-07-07
AT313486B (de)	1974-02-25
NL7007142A (de)	1970-11-19
IL34472A0 (en)	1970-07-19
BE750486A (fr)	1970-11-16

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