IE34226L - Sterile ampicillin suspensions - Google Patents
Sterile ampicillin suspensionsInfo
- Publication number
- IE34226L IE34226L IE700681A IE68170A IE34226L IE 34226 L IE34226 L IE 34226L IE 700681 A IE700681 A IE 700681A IE 68170 A IE68170 A IE 68170A IE 34226 L IE34226 L IE 34226L
- Authority
- IE
- Ireland
- Prior art keywords
- ampicillin
- microns
- ampicillin trihydrate
- particle size
- suspensions
- Prior art date
Links
- AVKUERGKIZMTKX-NJBDSQKTSA-N ampicillin Chemical compound C1([C@@H](N)C(=O)N[C@H]2[C@H]3SC([C@@H](N3C2=O)C(O)=O)(C)C)=CC=CC=C1 AVKUERGKIZMTKX-NJBDSQKTSA-N 0.000 title abstract 5
- 229960000723 ampicillin Drugs 0.000 title abstract 2
- 239000000725 suspension Substances 0.000 title abstract 2
- 229960003311 ampicillin trihydrate Drugs 0.000 abstract 3
- 239000000203 mixture Substances 0.000 abstract 3
- 239000002245 particle Substances 0.000 abstract 3
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 2
- IIZPXYDJLKNOIY-JXPKJXOSSA-N 1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphocholine Chemical compound CCCCCCCCCCCCCCCC(=O)OC[C@H](COP([O-])(=O)OCC[N+](C)(C)C)OC(=O)CCC\C=C/C\C=C/C\C=C/C\C=C/CCCCC IIZPXYDJLKNOIY-JXPKJXOSSA-N 0.000 abstract 1
- DPXJVFZANSGRMM-UHFFFAOYSA-N acetic acid;2,3,4,5,6-pentahydroxyhexanal;sodium Chemical compound [Na].CC(O)=O.OCC(O)C(O)C(O)C(O)C=O DPXJVFZANSGRMM-UHFFFAOYSA-N 0.000 abstract 1
- 230000002378 acidificating effect Effects 0.000 abstract 1
- 230000000844 anti-bacterial effect Effects 0.000 abstract 1
- 239000001768 carboxy methyl cellulose Substances 0.000 abstract 1
- 239000002270 dispersing agent Substances 0.000 abstract 1
- 239000007972 injectable composition Substances 0.000 abstract 1
- 238000002347 injection Methods 0.000 abstract 1
- 239000007924 injection Substances 0.000 abstract 1
- 235000010445 lecithin Nutrition 0.000 abstract 1
- 239000000787 lecithin Substances 0.000 abstract 1
- -1 lecithin Chemical compound 0.000 abstract 1
- 229940067606 lecithin Drugs 0.000 abstract 1
- 235000019812 sodium carboxymethyl cellulose Nutrition 0.000 abstract 1
- 229920001027 sodium carboxymethylcellulose Polymers 0.000 abstract 1
- 239000000375 suspending agent Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Abstract
1316625 Compositions containing ampicillin trihydrate E R SQUIBB & SONS INC 29 May 1970 [6 June 1969] 26124/70 Heading A5B [Also in Division C2] An antibacterial composition comprises sterile ampicillin trihydrate having a particle size in the range 5 to 50 microns, at least 50% of the particles of the ampicillin trihydrate having a particle size in the range 20 to 50 microns in admixture with a suspending agent e.g. sodium carboxymethylcellulose, and a dispersing agent e.g. lecithin, the composition being admixed with water before injection. Stable, long-acting injectable compositions comprise a suspension of the above ampicillin in water preferably containing an acidic buffer and having a pH from 4.0 to 7.0.
[GB1316625A]
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US83122569A | 1969-06-06 | 1969-06-06 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IE34226L true IE34226L (en) | 1970-12-06 |
| IE34226B1 IE34226B1 (en) | 1975-03-05 |
Family
ID=25258589
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IE681/70A IE34226B1 (en) | 1969-06-06 | 1970-05-26 | Alpha-aminobenzyl penicillins |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US3703511A (en) |
| JP (1) | JPS4913963B1 (en) |
| BE (1) | BE751261A (en) |
| BR (1) | BR6915337D0 (en) |
| CA (1) | CA946285A (en) |
| CH (1) | CH525240A (en) |
| DE (1) | DE2027044C3 (en) |
| DK (1) | DK126835B (en) |
| ES (1) | ES380448A1 (en) |
| FR (1) | FR2052937B1 (en) |
| GB (1) | GB1316625A (en) |
| IE (1) | IE34226B1 (en) |
| NL (1) | NL7008083A (en) |
| ZA (1) | ZA703565B (en) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1532993A (en) * | 1975-03-07 | 1978-11-22 | Beecham Group Ltd | Injectable antibiotic compositions |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NL6705789A (en) * | 1967-03-08 | 1968-09-09 |
-
1969
- 1969-06-06 US US831225A patent/US3703511A/en not_active Expired - Lifetime
- 1969-12-19 BR BR215337/69A patent/BR6915337D0/en unknown
-
1970
- 1970-05-26 IE IE681/70A patent/IE34226B1/en unknown
- 1970-05-26 CA CA083,754A patent/CA946285A/en not_active Expired
- 1970-05-26 ZA ZA703565A patent/ZA703565B/en unknown
- 1970-06-01 BE BE751261D patent/BE751261A/en not_active IP Right Cessation
- 1970-06-02 DE DE2027044A patent/DE2027044C3/en not_active Expired
- 1970-06-02 FR FR7020146A patent/FR2052937B1/fr not_active Expired
- 1970-06-03 NL NL7008083A patent/NL7008083A/xx unknown
- 1970-06-04 DK DK291670AA patent/DK126835B/en not_active IP Right Cessation
- 1970-06-04 CH CH839970A patent/CH525240A/en not_active IP Right Cessation
- 1970-06-05 GB GB2612470A patent/GB1316625A/en not_active Expired
- 1970-06-05 JP JP45048627A patent/JPS4913963B1/ja active Pending
- 1970-06-05 ES ES380448A patent/ES380448A1/en not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| JPS4913963B1 (en) | 1974-04-04 |
| DE2027044A1 (en) | 1970-12-17 |
| FR2052937B1 (en) | 1974-08-30 |
| DE2027044B2 (en) | 1980-01-17 |
| CH525240A (en) | 1972-07-15 |
| ES380448A1 (en) | 1972-09-01 |
| US3703511A (en) | 1972-11-21 |
| BE751261A (en) | 1970-12-01 |
| GB1316625A (en) | 1973-05-09 |
| IE34226B1 (en) | 1975-03-05 |
| FR2052937A1 (en) | 1971-04-16 |
| NL7008083A (en) | 1970-12-08 |
| DK126835B (en) | 1973-08-27 |
| CA946285A (en) | 1974-04-30 |
| DE2027044C3 (en) | 1980-09-11 |
| BR6915337D0 (en) | 1973-03-13 |
| ZA703565B (en) | 1971-01-27 |
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