IE34697L - Substituted 3-aminobenzoic acids - Google Patents
Substituted 3-aminobenzoic acidsInfo
- Publication number
- IE34697L IE34697L IE701409A IE140970A IE34697L IE 34697 L IE34697 L IE 34697L IE 701409 A IE701409 A IE 701409A IE 140970 A IE140970 A IE 140970A IE 34697 L IE34697 L IE 34697L
- Authority
- IE
- Ireland
- Prior art keywords
- substituted
- diuretic
- saluretic
- aminobenzoic acids
- unsatd
- Prior art date
Links
- XFDUHJPVQKIXHO-UHFFFAOYSA-N 3-aminobenzoic acid Chemical class NC1=CC=CC(C(O)=O)=C1 XFDUHJPVQKIXHO-UHFFFAOYSA-N 0.000 title 1
- 239000002934 diuretic Substances 0.000 abstract 3
- WPYMKLBDIGXBTP-UHFFFAOYSA-N benzoic acid Chemical compound OC(=O)C1=CC=CC=C1 WPYMKLBDIGXBTP-UHFFFAOYSA-N 0.000 abstract 2
- 230000001882 diuretic effect Effects 0.000 abstract 2
- ZAJAQTYSTDTMCU-UHFFFAOYSA-N 3-aminobenzenesulfonic acid Chemical compound NC1=CC=CC(S(O)(=O)=O)=C1 ZAJAQTYSTDTMCU-UHFFFAOYSA-N 0.000 abstract 1
- 239000005711 Benzoic acid Substances 0.000 abstract 1
- 102000003846 Carbonic anhydrases Human genes 0.000 abstract 1
- 108090000209 Carbonic anhydrases Proteins 0.000 abstract 1
- 125000002490 anilino group Chemical group [H]N(*)C1=C([H])C([H])=C([H])C([H])=C1[H] 0.000 abstract 1
- 125000003118 aryl group Chemical group 0.000 abstract 1
- 235000010233 benzoic acid Nutrition 0.000 abstract 1
- 150000002148 esters Chemical class 0.000 abstract 1
- -1 phenoxy, phenylthio Chemical group 0.000 abstract 1
- 230000000894 saliuretic effect Effects 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C313/00—Sulfinic acids; Sulfenic acids; Halides, esters or anhydrides thereof; Amides of sulfinic or sulfenic acids, i.e. compounds having singly-bound oxygen atoms of sulfinic or sulfenic groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
- C07C313/02—Sulfinic acids; Derivatives thereof
- C07C313/04—Sulfinic acids; Esters thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/10—Antioedematous agents; Diuretics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C317/00—Sulfones; Sulfoxides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
Diuretic saluretic metanilic acid derivs. Cpds. of the formula and their salts and esters: where A is phenoxy, phenylthio or anilino opt. substd.; R1 and R2 are 1-6C aliphatic radicals, satd. or unsatd., or mononuclear aryl (1-3C) alkyl radicals; n is 0 - 2; are diuretic and saluretic agents which do not inhibit carbonic anhydrase. Prepn. is from a 3-nitro-4-halo-5-chlorosulphonyl benzoic acid.
[FR2073392A1]
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB5691769 | 1969-11-20 | ||
| GB5184/70A GB1294699A (en) | 1969-11-20 | 1970-02-03 | Substituted 3-aminobenzoic acids |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IE34697L true IE34697L (en) | 1971-05-20 |
| IE34697B1 IE34697B1 (en) | 1975-07-23 |
Family
ID=26239710
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IE1409/70A IE34697B1 (en) | 1969-11-20 | 1970-11-05 | Substituted 3-aminobenzoic acids |
Country Status (9)
| Country | Link |
|---|---|
| JP (1) | JPS4936704B1 (en) |
| AT (1) | AT305980B (en) |
| AU (1) | AU2217470A (en) |
| BE (1) | BE759233A (en) |
| DE (1) | DE2056758A1 (en) |
| FR (1) | FR2073392A1 (en) |
| IE (1) | IE34697B1 (en) |
| IL (1) | IL35612A0 (en) |
| NL (1) | NL7017021A (en) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1287926A (en) * | 1969-12-16 | 1972-09-06 | ||
| GB1317941A (en) * | 1970-06-18 | 1973-05-23 | Leo Pharm Prod Ltd | Amino-benzoic acid derivatives |
| DE4240708A1 (en) * | 1992-12-03 | 1994-06-09 | Bayer Ag | Process for the preparation of sodium salts of aromatic sulfinic acids containing nitro groups |
-
0
- BE BE759233D patent/BE759233A/en unknown
-
1970
- 1970-11-05 IE IE1409/70A patent/IE34697B1/en unknown
- 1970-11-09 IL IL35612A patent/IL35612A0/en unknown
- 1970-11-12 AU AU22174/70A patent/AU2217470A/en not_active Expired
- 1970-11-16 AT AT1028870A patent/AT305980B/en not_active IP Right Cessation
- 1970-11-18 DE DE19702056758 patent/DE2056758A1/en active Pending
- 1970-11-19 FR FR7041514A patent/FR2073392A1/en active Granted
- 1970-11-20 JP JP45102399A patent/JPS4936704B1/ja active Pending
- 1970-11-20 NL NL7017021A patent/NL7017021A/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| JPS4936704B1 (en) | 1974-10-02 |
| BE759233A (en) | 1971-05-21 |
| FR2073392B1 (en) | 1973-08-10 |
| IE34697B1 (en) | 1975-07-23 |
| AT305980B (en) | 1973-03-26 |
| DE2056758A1 (en) | 1971-05-27 |
| IL35612A0 (en) | 1971-01-28 |
| AU2217470A (en) | 1972-05-18 |
| FR2073392A1 (en) | 1971-10-01 |
| NL7017021A (en) | 1971-05-24 |
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