IE34737L - Arabinofuranosyl purines - Google Patents
Arabinofuranosyl purinesInfo
- Publication number
- IE34737L IE34737L IE701470A IE147070A IE34737L IE 34737 L IE34737 L IE 34737L IE 701470 A IE701470 A IE 701470A IE 147070 A IE147070 A IE 147070A IE 34737 L IE34737 L IE 34737L
- Authority
- IE
- Ireland
- Prior art keywords
- amino
- arabinofuranosyl
- purines
- compounds
- us3666856a
- Prior art date
Links
- -1 Arabinofuranosyl purines Chemical class 0.000 title 1
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 4
- 150000001875 compounds Chemical class 0.000 abstract 2
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical group [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- 125000003282 alkyl amino group Chemical group 0.000 abstract 1
- 239000003443 antiviral agent Substances 0.000 abstract 1
- 229940121357 antivirals Drugs 0.000 abstract 1
- 229910052739 hydrogen Chemical group 0.000 abstract 1
- 239000001257 hydrogen Chemical group 0.000 abstract 1
- 239000003018 immunosuppressive agent Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/16—Purine radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Virology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
Abstract
Compounds of the formula WHERE R1 is amino or lower alkylamino, R2 is amino or hydrogen and pharmaceutically acceptable salts thereof, provided that when R1 is amino, R2 is amino. The compounds are useful as immune suppressants and as antivirals.
[US3666856A]
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IE877/74A IE34738B1 (en) | 1969-11-17 | 1970-11-16 | Amino purine derivatives |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US87744369A | 1969-11-17 | 1969-11-17 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IE34737L true IE34737L (en) | 1971-05-17 |
| IE34737B1 IE34737B1 (en) | 1975-08-06 |
Family
ID=25369972
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IE1470/70A IE34737B1 (en) | 1969-11-17 | 1970-11-16 | Amino purine derivatives |
Country Status (26)
| Country | Link |
|---|---|
| US (1) | US3666856A (en) |
| JP (1) | JPS5429520B1 (en) |
| AT (1) | AT309696B (en) |
| BE (1) | BE759011A (en) |
| BR (1) | BR6915136D0 (en) |
| CA (1) | CA967564A (en) |
| CH (2) | CH555344A (en) |
| CS (1) | CS181701B2 (en) |
| DE (1) | DE2056327C2 (en) |
| DK (1) | DK128117B (en) |
| ES (2) | ES385590A1 (en) |
| FI (1) | FI54315C (en) |
| FR (1) | FR2073364B1 (en) |
| GB (2) | GB1338906A (en) |
| HU (1) | HU163812B (en) |
| IE (1) | IE34737B1 (en) |
| IL (1) | IL35658A (en) |
| LU (1) | LU62071A1 (en) |
| MC (1) | MC869A1 (en) |
| NL (1) | NL171589C (en) |
| NO (1) | NO128156B (en) |
| PL (1) | PL81167B1 (en) |
| SE (1) | SE385374B (en) |
| YU (2) | YU35033B (en) |
| ZA (1) | ZA707722B (en) |
| ZM (1) | ZM12970A1 (en) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4081534A (en) * | 1973-09-11 | 1978-03-28 | Burroughs Wellcome Co. | Amino purine nucleosides as autoimmune suppressant agents |
| GB1562899A (en) * | 1975-06-17 | 1980-03-19 | Wellcome Found | Pharmaceutical compositions containing substituted 9-( -d-arabnofuranosyl)purine-5'-phosphate and salts thereof |
| US4210745A (en) * | 1978-01-04 | 1980-07-01 | The United States Of America As Represented By The Department Of Health, Education And Welfare | Procedure for the preparation of 9-β-D-arabinofuranosyl-2-fluoroadenine |
| DE3319282A1 (en) * | 1983-05-27 | 1984-11-29 | Gödecke AG, 1000 Berlin | USE OF ADENOSINE IN THE TREATMENT OF HERPES |
| GB8712745D0 (en) * | 1987-05-30 | 1987-07-01 | Wellcome Found | Antiviral compounds |
| WO1989008658A1 (en) * | 1988-03-16 | 1989-09-21 | Scripps Clinic And Research Foundation | Substituted adenine derivatives useful as therapeutic agents |
| IE882585L (en) * | 1988-08-25 | 1990-02-25 | Prendergast Patrick T | Viral treatment system |
| US5292725A (en) * | 1988-08-25 | 1994-03-08 | Prendergast Patrick T | Administering particular compounds against various parasites, mycoplasmas, other indications and other infections |
| US5681941A (en) * | 1990-01-11 | 1997-10-28 | Isis Pharmaceuticals, Inc. | Substituted purines and oligonucleotide cross-linking |
| US5308837A (en) * | 1990-08-22 | 1994-05-03 | Merrell Dow Pharmaceuticals Inc. | 5'-amine substituted adenosine analogs as immunosuppressants |
| US6338963B1 (en) | 1994-07-25 | 2002-01-15 | Neotherapeutics, Inc. | Use of carbon monoxide dependent guanylyl cyclase modifiers to stimulate neuritogenesis |
| US6232463B1 (en) | 1997-10-09 | 2001-05-15 | Isis Pharmaceuticals, Inc. | Substituted purines and oligonucleotide cross-linking |
| US6303617B1 (en) | 1998-05-04 | 2001-10-16 | Neotherapeutics, Inc. | Serotonin-like 9-substituted hypoxanthine and methods of use |
| US6288069B1 (en) | 1999-11-16 | 2001-09-11 | Neotherapeutics, Inc. | Use of 9-substituted hypoxanthine derivatives to stimulate regeneration of nervous tissue |
| US6407237B1 (en) | 2001-02-21 | 2002-06-18 | Neotherapeutics, Inc. | Crystal forms of 9-substituted hypoxanthine derivatives |
| US6849735B1 (en) | 2000-06-23 | 2005-02-01 | Merck Eprova Ag | Methods of synthesis for 9-substituted hypoxanthine derivatives |
| ES2385931T3 (en) | 2000-07-07 | 2012-08-03 | Spectrum Pharmaceuticals, Inc. | METHODS FOR THE TREATMENT OF PERIPHERAL NEUROPATHY INDUCED BY A DISEASE AND RELATED AFFECTIONS. |
| US6759427B2 (en) * | 2001-04-20 | 2004-07-06 | Spectrum Pharmaceuticals, Inc. | Synthesis and methods of use of tetrahydroindolone analogues and derivatives |
| US20030055249A1 (en) * | 2001-07-17 | 2003-03-20 | Fick David B. | Synthesis and methods of use of pyrimidine analogues and derivatives |
| CN105237602B (en) * | 2015-06-25 | 2018-05-18 | 新乡学院 | A kind of preparation method of 2- amino arabinosy ladenosine |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1070413A (en) * | 1962-11-15 | 1967-06-01 | Sankyo Co | A process for preparing purine and pyrimidine nucleosides |
| US3407191A (en) * | 1966-08-29 | 1968-10-22 | Lilly Co Eli | Adamantoate esters of nucleosides |
| JPH1097965A (en) * | 1996-09-20 | 1998-04-14 | Sony Corp | Production management method |
-
0
- BE BE759011D patent/BE759011A/en not_active IP Right Cessation
-
1969
- 1969-11-17 US US877443A patent/US3666856A/en not_active Expired - Lifetime
- 1969-12-15 BR BR215136/69A patent/BR6915136D0/en unknown
-
1970
- 1970-11-10 MC MC923A patent/MC869A1/en unknown
- 1970-11-16 IE IE1470/70A patent/IE34737B1/en unknown
- 1970-11-16 PL PL1970144449A patent/PL81167B1/pl unknown
- 1970-11-16 DE DE2056327A patent/DE2056327C2/en not_active Expired
- 1970-11-16 AT AT1028370A patent/AT309696B/en not_active IP Right Cessation
- 1970-11-16 JP JP10095870A patent/JPS5429520B1/ja active Pending
- 1970-11-16 ZA ZA707722A patent/ZA707722B/en unknown
- 1970-11-16 GB GB2751373A patent/GB1338906A/en not_active Expired
- 1970-11-16 NO NO04378/70A patent/NO128156B/no unknown
- 1970-11-16 FR FR7040956A patent/FR2073364B1/fr not_active Expired
- 1970-11-16 LU LU62071D patent/LU62071A1/xx unknown
- 1970-11-16 ES ES385590A patent/ES385590A1/en not_active Expired
- 1970-11-16 YU YU2806/70A patent/YU35033B/en unknown
- 1970-11-16 FI FI3069/70A patent/FI54315C/en active
- 1970-11-16 NL NLAANVRAGE7016766,A patent/NL171589C/en not_active IP Right Cessation
- 1970-11-16 GB GB5450270A patent/GB1338905A/en not_active Expired
- 1970-11-16 DK DK581070AA patent/DK128117B/en not_active IP Right Cessation
- 1970-11-16 CA CA098,272A patent/CA967564A/en not_active Expired
- 1970-11-16 CH CH1694070A patent/CH555344A/en not_active IP Right Cessation
- 1970-11-16 CS CS7000007720A patent/CS181701B2/en unknown
- 1970-11-16 SE SE7015440A patent/SE385374B/en unknown
- 1970-11-16 HU HUWE425A patent/HU163812B/hu unknown
- 1970-11-16 CH CH1431873A patent/CH555833A/en not_active IP Right Cessation
- 1970-11-16 IL IL35658A patent/IL35658A/en unknown
- 1970-11-17 ZM ZM129/70A patent/ZM12970A1/en unknown
-
1973
- 1973-04-16 ES ES413787A patent/ES413787A1/en not_active Expired
-
1978
- 1978-08-24 YU YU2019/78A patent/YU35034B/en unknown
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