IE35662L - 4-hydroxy cinnolines. - Google Patents
4-hydroxy cinnolines.Info
- Publication number
- IE35662L IE35662L IE711194A IE119471A IE35662L IE 35662 L IE35662 L IE 35662L IE 711194 A IE711194 A IE 711194A IE 119471 A IE119471 A IE 119471A IE 35662 L IE35662 L IE 35662L
- Authority
- IE
- Ireland
- Prior art keywords
- alkoxy
- cpds
- formula
- opt
- substd
- Prior art date
Links
- UFMBERDMCRCVSM-UHFFFAOYSA-N 1h-cinnolin-4-one Chemical class C1=CC=C2C(O)=CN=NC2=C1 UFMBERDMCRCVSM-UHFFFAOYSA-N 0.000 title 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 3
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 229910052736 halogen Inorganic materials 0.000 abstract 2
- 150000002367 halogens Chemical class 0.000 abstract 2
- 125000000951 phenoxy group Chemical group [H]C1=C([H])C([H])=C(O*)C([H])=C1[H] 0.000 abstract 2
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 2
- JCXJVPUVTGWSNB-UHFFFAOYSA-N Nitrogen dioxide Chemical compound O=[N]=O JCXJVPUVTGWSNB-UHFFFAOYSA-N 0.000 abstract 1
- 125000005083 alkoxyalkoxy group Chemical group 0.000 abstract 1
- 208000006673 asthma Diseases 0.000 abstract 1
- 125000000753 cycloalkyl group Chemical group 0.000 abstract 1
- 239000003937 drug carrier Substances 0.000 abstract 1
- 239000008024 pharmaceutical diluent Substances 0.000 abstract 1
- 125000002071 phenylalkoxy group Chemical group 0.000 abstract 1
- 125000003884 phenylalkyl group Chemical group 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C251/00—Compounds containing nitrogen atoms doubly-bound to a carbon skeleton
- C07C251/72—Hydrazones
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
The compsns contn. cpds. of formula (I): (in which R1 is OH, 1-66C alkoxy, 3-6C alkoxyalkoxy, 7-10C phenyl alkoxy or phenoxy, and the benzene ring A may opt. be substd. by 1-4 gps. selected from 1-10C alkyl, 5-7C cycloalkyl, 1-5C alkoxy, halogen, 7-10C phenylalkyl or phenoxy, or phenyl opt. substd. by 1-3 gps selected from 1-3C alkyl, 1-3C alkoxy, NO2 or halogen) opt. in the form of a pharmaceutically accetable salt, together with a pharmaceutical carrier or diluent. Many of the cpds. of formula (I) are new and are prepd. by cyclising cpds. of formula A-NH.N=C(COX)2. (I) are esp. useful for the treatment of asthma.
[FR2111670A1]
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB4928270 | 1970-10-16 | ||
| GB3848371 | 1971-08-17 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IE35662L true IE35662L (en) | 1972-04-16 |
| IE35662B1 IE35662B1 (en) | 1976-04-14 |
Family
ID=26263823
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IE1194/71A IE35662B1 (en) | 1970-10-16 | 1971-09-24 | Pharmaceutical compositions |
Country Status (14)
| Country | Link |
|---|---|
| AT (1) | AT310757B (en) |
| BE (1) | BE774033A (en) |
| CA (1) | CA969953A (en) |
| CH (1) | CH573410A5 (en) |
| DE (1) | DE2151487A1 (en) |
| DK (1) | DK131149B (en) |
| ES (1) | ES396073A1 (en) |
| FR (1) | FR2111670A1 (en) |
| HU (1) | HU162813B (en) |
| IE (1) | IE35662B1 (en) |
| IL (1) | IL37839A (en) |
| NL (1) | NL7114259A (en) |
| NO (1) | NO133198C (en) |
| SU (1) | SU493969A3 (en) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1474399A (en) * | 1974-08-19 | 1977-05-25 | Ici Ltd | Cinnolin-3-yl carboxylic acids and derivatives thereof |
| GB1472766A (en) * | 1974-11-07 | 1977-05-04 | Ici Ltd | Hydroxycinnoline derivatives processes for their preparation and their use in pharmaceutical compositions |
| US4379929A (en) | 1981-03-19 | 1983-04-12 | Eli Lilly And Company | 4(1H)-Oxocinnoline-3-carboxylic acid derivatives |
| US4756740A (en) * | 1983-09-14 | 1988-07-12 | Lafarge Coppee | Pollen suppressant comprising a fused pyridazine |
| RU2007131400A (en) | 2005-03-01 | 2009-04-10 | Вайет (Us) | COMPOUNDS OF CINNOLINE AND THEIR APPLICATION AS MODULATORS OF LIVER X-RECEPTORS |
-
1971
- 1971-09-24 IE IE1194/71A patent/IE35662B1/en unknown
- 1971-09-28 CA CA123,923A patent/CA969953A/en not_active Expired
- 1971-10-05 IL IL37839A patent/IL37839A/en unknown
- 1971-10-05 DK DK484171AA patent/DK131149B/en unknown
- 1971-10-14 CH CH1500071A patent/CH573410A5/xx not_active IP Right Cessation
- 1971-10-15 DE DE19712151487 patent/DE2151487A1/en active Pending
- 1971-10-15 BE BE774033A patent/BE774033A/en unknown
- 1971-10-15 NL NL7114259A patent/NL7114259A/xx unknown
- 1971-10-15 FR FR7137218A patent/FR2111670A1/en active Granted
- 1971-10-15 NO NO3825/71A patent/NO133198C/no unknown
- 1971-10-16 HU HUIE480A patent/HU162813B/hu unknown
- 1971-10-16 ES ES396073A patent/ES396073A1/en not_active Expired
- 1971-10-18 AT AT942572A patent/AT310757B/en not_active IP Right Cessation
-
1973
- 1973-02-06 SU SU731880093A patent/SU493969A3/en active
Also Published As
| Publication number | Publication date |
|---|---|
| FR2111670A1 (en) | 1972-06-09 |
| HU162813B (en) | 1973-04-28 |
| IL37839A0 (en) | 1971-12-29 |
| CA969953A (en) | 1975-06-24 |
| ES396073A1 (en) | 1974-10-16 |
| DE2151487A1 (en) | 1972-04-20 |
| FR2111670B1 (en) | 1975-10-10 |
| AU3454871A (en) | 1973-04-19 |
| SU493969A3 (en) | 1975-11-28 |
| NO133198C (en) | 1976-03-24 |
| DK131149B (en) | 1975-06-02 |
| BE774033A (en) | 1972-04-17 |
| NL7114259A (en) | 1972-04-18 |
| IE35662B1 (en) | 1976-04-14 |
| DK131149C (en) | 1975-11-10 |
| AT310757B (en) | 1973-10-10 |
| CH573410A5 (en) | 1976-03-15 |
| IL37839A (en) | 1974-12-31 |
| NO133198B (en) | 1975-12-15 |
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