IE35820L - Preparation of n-[2-(diethylamino)¹ethyl]-2-methoxy-4-amino-5-chlorobenzamide - Google Patents
Preparation of n-[2-(diethylamino)¹ethyl]-2-methoxy-4-amino-5-chlorobenzamideInfo
- Publication number
- IE35820L IE35820L IE711458A IE145871A IE35820L IE 35820 L IE35820 L IE 35820L IE 711458 A IE711458 A IE 711458A IE 145871 A IE145871 A IE 145871A IE 35820 L IE35820 L IE 35820L
- Authority
- IE
- Ireland
- Prior art keywords
- diethylamino
- amino
- anisamide
- chloro
- methyl
- Prior art date
Links
- WUBBRNOQWQTFEX-UHFFFAOYSA-N 4-aminosalicylic acid Chemical compound NC1=CC=C(C(O)=O)C(O)=C1 WUBBRNOQWQTFEX-UHFFFAOYSA-N 0.000 abstract 1
- GUCPYIYFQVTFSI-UHFFFAOYSA-N 4-methoxybenzamide Chemical class COC1=CC=C(C(N)=O)C=C1 GUCPYIYFQVTFSI-UHFFFAOYSA-N 0.000 abstract 1
- YYROPELSRYBVMQ-UHFFFAOYSA-N 4-toluenesulfonyl chloride Chemical compound CC1=CC=C(S(Cl)(=O)=O)C=C1 YYROPELSRYBVMQ-UHFFFAOYSA-N 0.000 abstract 1
- IVNLDCDGUGEXNC-UHFFFAOYSA-N 5-chloro-N-[2-(diethylamino)ethyl]-2-methoxy-4-[(4-methylphenyl)sulfonylamino]benzamide Chemical compound C(C)N(CCNC(C1=C(C=C(C(=C1)Cl)NS(=O)(=O)C1=CC=C(C=C1)C)OC)=O)CC IVNLDCDGUGEXNC-UHFFFAOYSA-N 0.000 abstract 1
- 229960004909 aminosalicylic acid Drugs 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 238000005660 chlorination reaction Methods 0.000 abstract 1
- VAYGXNSJCAHWJZ-UHFFFAOYSA-N dimethyl sulfate Chemical compound COS(=O)(=O)OC VAYGXNSJCAHWJZ-UHFFFAOYSA-N 0.000 abstract 1
- 230000003301 hydrolyzing effect Effects 0.000 abstract 1
- GWSFLRZIQWGYGT-UHFFFAOYSA-N methyl 2-methoxy-4-[(4-methylphenyl)sulfonylamino]benzoate Chemical compound C1=C(OC)C(C(=O)OC)=CC=C1NS(=O)(=O)C1=CC=C(C)C=C1 GWSFLRZIQWGYGT-UHFFFAOYSA-N 0.000 abstract 1
- QMUDKPUZLXHTEX-UHFFFAOYSA-N methyl 5-chloro-2-methoxy-4-[(4-methylphenyl)sulfonylamino]benzoate Chemical compound C1=C(OC)C(C(=O)OC)=CC(Cl)=C1NS(=O)(=O)C1=CC=C(C)C=C1 QMUDKPUZLXHTEX-UHFFFAOYSA-N 0.000 abstract 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
- TTWJBBZEZQICBI-UHFFFAOYSA-N metoclopramide Chemical compound CCN(CC)CCNC(=O)C1=CC(Cl)=C(N)C=C1OC TTWJBBZEZQICBI-UHFFFAOYSA-N 0.000 abstract 1
- UDGSVBYJWHOHNN-UHFFFAOYSA-N n',n'-diethylethane-1,2-diamine Chemical compound CCN(CC)CCN UDGSVBYJWHOHNN-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/475—Quinolines; Isoquinolines having an indole ring, e.g. yohimbine, reserpine, strychnine, vinblastine
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
- C07C237/28—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a non-condensed six-membered aromatic ring of the carbon skeleton
- C07C237/34—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a non-condensed six-membered aromatic ring of the carbon skeleton having the nitrogen atom of the carboxamide group bound to an acyclic carbon atom of a hydrocarbon radical substituted by nitrogen atoms not being part of nitro or nitroso groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
1328580 Anisamide derivative FRATMANN AG 6 Dec 1971 [4 Aug 1971] 56496/71 Heading C2C 4 - Amino - 5 - chloro - N - [2 - (diethylamino)- ethyl] - o - anisamide is prepared by hydrolysing 5 - chloro - N - [2 - (diethylamino)ethyl] - 4- (p - toluenesulphonamido)- o - anisamide, obtained by reacting 2-(diethylamino)ethylamine with methyl 5 - chloro - 4 - (p - toluenesulphonamido) - o - anisate, resulting from the chlorination of methyl 4-(p-toluensulphonamido)- o-anisate, which is made by reacting p-toluenesulphonyl chloride with methyl 4-amino-oanisate obtained by treating p-aminosalicylic acid with dimethyl sulphate. Reference has been directed by the Comptroller to Specification 994,023.
[GB1328580A]
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH1144371 | 1971-08-04 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IE35820L true IE35820L (en) | 1973-02-04 |
| IE35820B1 IE35820B1 (en) | 1976-05-26 |
Family
ID=4373540
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IE1458/71A IE35820B1 (en) | 1971-08-04 | 1971-11-18 | Preparation of n-(2-(diethylamino)ethyl)-2-methoxy-4-amino-5-chlorobenzamide |
Country Status (27)
| Country | Link |
|---|---|
| JP (1) | JPS557422B1 (en) |
| BE (1) | BE774300A (en) |
| BG (1) | BG19590A3 (en) |
| CA (1) | CA975798A (en) |
| CH (1) | CH547262A (en) |
| CS (1) | CS171164B2 (en) |
| DE (1) | DE2152369A1 (en) |
| DK (1) | DK129036B (en) |
| ES (1) | ES396717A1 (en) |
| FI (1) | FI53968C (en) |
| FR (1) | FR2111373A5 (en) |
| GB (1) | GB1328580A (en) |
| HU (1) | HU163868B (en) |
| IE (1) | IE35820B1 (en) |
| IL (1) | IL38097A0 (en) |
| IT (1) | IT1050359B (en) |
| LU (1) | LU64249A1 (en) |
| MC (1) | MC895A1 (en) |
| NL (1) | NL7114903A (en) |
| NO (1) | NO133890C (en) |
| OA (1) | OA03927A (en) |
| PL (1) | PL84572B1 (en) |
| RO (1) | RO62478A (en) |
| SE (1) | SE366298B (en) |
| YU (1) | YU34787B (en) |
| ZA (1) | ZA717542B (en) |
| ZM (1) | ZM17171A1 (en) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5759075U (en) * | 1980-09-20 | 1982-04-07 | ||
| JPS5882560U (en) * | 1981-11-30 | 1983-06-04 | いすゞ自動車株式会社 | gasket |
-
1971
- 1971-08-04 CH CH1144371A patent/CH547262A/en not_active IP Right Cessation
- 1971-10-14 FR FR7136942A patent/FR2111373A5/fr not_active Expired
- 1971-10-20 IT IT30087/71A patent/IT1050359B/en active
- 1971-10-21 DE DE19712152369 patent/DE2152369A1/en active Pending
- 1971-10-22 BE BE774300A patent/BE774300A/en not_active IP Right Cessation
- 1971-10-28 NL NL7114903A patent/NL7114903A/xx not_active Application Discontinuation
- 1971-11-05 ES ES396717A patent/ES396717A1/en not_active Expired
- 1971-11-08 IL IL38097A patent/IL38097A0/en unknown
- 1971-11-08 CA CA127,135A patent/CA975798A/en not_active Expired
- 1971-11-09 YU YU2822/71A patent/YU34787B/en unknown
- 1971-11-09 SE SE14276/71A patent/SE366298B/xx unknown
- 1971-11-09 ZA ZA717542A patent/ZA717542B/en unknown
- 1971-11-09 MC MC955A patent/MC895A1/en unknown
- 1971-11-11 LU LU64249D patent/LU64249A1/xx unknown
- 1971-11-18 IE IE1458/71A patent/IE35820B1/en unknown
- 1971-11-22 ZM ZM171/71A patent/ZM17171A1/en unknown
- 1971-11-24 FI FI3360/71A patent/FI53968C/en active
- 1971-11-29 DK DK584471AA patent/DK129036B/en unknown
- 1971-11-30 CS CS8338A patent/CS171164B2/cs unknown
- 1971-12-01 HU HUFA899A patent/HU163868B/hu unknown
- 1971-12-03 BG BG019160A patent/BG19590A3/en unknown
- 1971-12-06 GB GB5649671A patent/GB1328580A/en not_active Expired
- 1971-12-07 OA OA54433A patent/OA03927A/en unknown
- 1971-12-30 NO NO4948/71A patent/NO133890C/no unknown
- 1971-12-31 JP JP723950A patent/JPS557422B1/ja active Pending
-
1972
- 1972-01-15 RO RO7200069411A patent/RO62478A/en unknown
- 1972-03-30 PL PL1972154414A patent/PL84572B1/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| IE35820B1 (en) | 1976-05-26 |
| AU3572071A (en) | 1973-05-24 |
| FI53968B (en) | 1978-05-31 |
| GB1328580A (en) | 1973-08-30 |
| IT1050359B (en) | 1981-03-10 |
| ZM17171A1 (en) | 1972-07-21 |
| JPS557422B1 (en) | 1980-02-25 |
| ES396717A1 (en) | 1974-05-16 |
| YU282271A (en) | 1979-09-10 |
| CH547262A (en) | 1974-03-29 |
| IL38097A0 (en) | 1972-01-27 |
| OA03927A (en) | 1975-08-14 |
| NO133890C (en) | 1976-07-14 |
| FI53968C (en) | 1978-09-11 |
| SE366298B (en) | 1974-04-22 |
| DE2152369A1 (en) | 1973-02-15 |
| NL7114903A (en) | 1973-02-06 |
| HU163868B (en) | 1973-11-28 |
| DK129036B (en) | 1974-08-12 |
| FR2111373A5 (en) | 1972-06-02 |
| CA975798A (en) | 1975-10-07 |
| YU34787B (en) | 1980-03-15 |
| NO133890B (en) | 1976-04-05 |
| LU64249A1 (en) | 1972-06-02 |
| BE774300A (en) | 1972-04-24 |
| ZA717542B (en) | 1972-08-30 |
| PL84572B1 (en) | 1976-04-30 |
| RO62478A (en) | 1978-03-15 |
| CS171164B2 (en) | 1976-10-29 |
| BG19590A3 (en) | 1975-06-25 |
| MC895A1 (en) | 1972-06-22 |
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