IE37171L - Anti-hypertensive compositions - Google Patents
Anti-hypertensive compositionsInfo
- Publication number
- IE37171L IE37171L IE730159A IE15973A IE37171L IE 37171 L IE37171 L IE 37171L IE 730159 A IE730159 A IE 730159A IE 15973 A IE15973 A IE 15973A IE 37171 L IE37171 L IE 37171L
- Authority
- IE
- Ireland
- Prior art keywords
- alkyl
- compositions
- alkenyl
- hydroxy
- phenyl
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title abstract 4
- 230000003276 anti-hypertensive effect Effects 0.000 title abstract 3
- 125000000217 alkyl group Chemical group 0.000 abstract 5
- 125000003342 alkenyl group Chemical group 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 2
- 125000004209 (C1-C8) alkyl group Chemical group 0.000 abstract 1
- 125000004429 atom Chemical group 0.000 abstract 1
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 1
- 239000003085 diluting agent Substances 0.000 abstract 1
- 125000005843 halogen group Chemical group 0.000 abstract 1
- 125000000623 heterocyclic group Chemical group 0.000 abstract 1
- 125000004433 nitrogen atom Chemical group N* 0.000 abstract 1
- 238000007911 parenteral administration Methods 0.000 abstract 1
- 239000000546 pharmaceutical excipient Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/50—Pyridazines; Hydrogenated pyridazines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
1378102 Antihypertensive compositions GRUPPO LEPETIT SpA 22 Jan 1973 [14 March 1972] 3208/73 Heading A5B Antihypertensive compositions comprise a compound of the general formula wherein R and R 1 are each halogen atoms or C 1-8 alkyl groups, in association with a compound of the general formula: wherein X is H or Cl, R, is H, C 1-8 alkyl, alkenyl or hydroxy-C 1-4 alkyl, R 3 is C,-alkyl, C 2-8 alkenyl, hydroxy-C 1-4 alkyl or phenyl, or R 2 and R 3 together with the nitrogen atom form a heterocyclic ring of 5-7 atoms, R 4 is H 2 or a group =CR 5 R 6 wherein R 5 is H or C 1-8 alkyl and R 6 is C 1-8 alkyl, carboxy or phenyl. The compositions may be in conventional forms for oral and parenteral administration comprising conventional diluents and excipients.
[GB1378102A]
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT2179872 | 1972-03-14 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IE37171L true IE37171L (en) | 1973-09-14 |
| IE37171B1 IE37171B1 (en) | 1977-05-25 |
Family
ID=11186980
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IE159/73A IE37171B1 (en) | 1972-03-14 | 1973-01-31 | Antihypertensive compositions |
Country Status (12)
| Country | Link |
|---|---|
| JP (1) | JPS4899314A (en) |
| AU (1) | AU473956B2 (en) |
| BE (1) | BE796759A (en) |
| CA (1) | CA1018458A (en) |
| DE (1) | DE2308240C3 (en) |
| FR (1) | FR2181820B1 (en) |
| GB (1) | GB1378102A (en) |
| IE (1) | IE37171B1 (en) |
| IL (1) | IL41405A (en) |
| NL (1) | NL149704B (en) |
| PH (1) | PH10526A (en) |
| ZA (1) | ZA73478B (en) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE3294T1 (en) * | 1978-10-02 | 1983-05-15 | Gruppo Lepetit S.P.A. | 6-AMINOSUBSTITUTED N-PYRROLYL-3-PYRIDAZINAMINES, THEIR PREPARATION AND PHARMACEUTICAL ANTIHYPERTENSIVE COMPOSITIONS CONTAINING THEM. |
-
1973
- 1973-01-22 GB GB320873A patent/GB1378102A/en not_active Expired
- 1973-01-23 ZA ZA730478A patent/ZA73478B/en unknown
- 1973-01-26 IL IL41405A patent/IL41405A/en unknown
- 1973-01-31 IE IE159/73A patent/IE37171B1/en unknown
- 1973-02-20 DE DE2308240A patent/DE2308240C3/en not_active Expired
- 1973-02-21 NL NL737302391A patent/NL149704B/en not_active IP Right Cessation
- 1973-03-02 CA CA165,091A patent/CA1018458A/en not_active Expired
- 1973-03-13 JP JP48029353A patent/JPS4899314A/ja active Pending
- 1973-03-13 PH PH14424A patent/PH10526A/en unknown
- 1973-03-14 BE BE128785A patent/BE796759A/en unknown
- 1973-03-14 AU AU53270/73A patent/AU473956B2/en not_active Expired
- 1973-03-14 FR FR7309163A patent/FR2181820B1/fr not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| AU5327073A (en) | 1974-09-19 |
| JPS4899314A (en) | 1973-12-15 |
| DE2308240A1 (en) | 1973-09-20 |
| IL41405A0 (en) | 1973-03-30 |
| FR2181820B1 (en) | 1975-10-31 |
| NL149704B (en) | 1976-06-15 |
| ZA73478B (en) | 1973-10-31 |
| BE796759A (en) | 1973-07-02 |
| AU473956B2 (en) | 1976-07-08 |
| IL41405A (en) | 1976-04-30 |
| FR2181820A1 (en) | 1973-12-07 |
| DE2308240B2 (en) | 1977-11-24 |
| DE2308240C3 (en) | 1978-07-13 |
| CA1018458A (en) | 1977-10-04 |
| GB1378102A (en) | 1974-12-18 |
| IE37171B1 (en) | 1977-05-25 |
| NL7302391A (en) | 1973-09-18 |
| PH10526A (en) | 1977-05-30 |
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