IE38825B1 - Stable viral preparations - Google Patents

Stable viral preparations

Info

Publication number: IE38825B1
Authority: IE; Ireland
Prior art keywords: cell; compositions; viruses; free; viral preparations
Prior art date: 1973-02-09

Application number

IE203/74A

Other languages

English (en)

Other versions

IE38825L (en

Original Assignee

Rit Rech Ind Therapeut

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1973-02-09

Filing date

1974-02-04

Publication date

1978-06-07

1974-02-04 Application filed by Rit Rech Ind Therapeut filed Critical Rit Rech Ind Therapeut

1974-08-09 Publication of IE38825L publication Critical patent/IE38825L/xx

1978-06-07 Publication of IE38825B1 publication Critical patent/IE38825B1/xx

Links

238000002360 preparation method Methods 0.000 title abstract 2
230000003612 virological effect Effects 0.000 title 1
241000700605 Viruses Species 0.000 abstract 4
239000000203 mixture Substances 0.000 abstract 3
WHUUTDBJXJRKMK-VKHMYHEASA-N L-glutamic acid Chemical compound OC(=O)[C@@H](N)CCC(O)=O WHUUTDBJXJRKMK-VKHMYHEASA-N 0.000 abstract 1
229930006000 Sucrose Natural products 0.000 abstract 1
CZMRCDWAGMRECN-UGDNZRGBSA-N Sucrose Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 CZMRCDWAGMRECN-UGDNZRGBSA-N 0.000 abstract 1
239000008366 buffered solution Substances 0.000 abstract 1
239000002738 chelating agent Substances 0.000 abstract 1
238000000605 extraction Methods 0.000 abstract 1
238000004108 freeze drying Methods 0.000 abstract 1
229930195712 glutamate Natural products 0.000 abstract 1
235000013855 polyvinylpyrrolidone Nutrition 0.000 abstract 1
229920000036 polyvinylpyrrolidone Polymers 0.000 abstract 1
239000001267 polyvinylpyrrolidone Substances 0.000 abstract 1
230000000087 stabilizing effect Effects 0.000 abstract 1
239000005720 sucrose Substances 0.000 abstract 1
229960005486 vaccine Drugs 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A61K39/245—Herpetoviridae, e.g. herpes simplex virus
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/525—Virus
- A61K2039/5254—Virus avirulent or attenuated
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/16011—Herpesviridae
- C12N2710/16311—Mardivirus, e.g. Gallid herpesvirus 2, Marek-like viruses, turkey HV
- C12N2710/16334—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/16011—Herpesviridae
- C12N2710/16311—Mardivirus, e.g. Gallid herpesvirus 2, Marek-like viruses, turkey HV
- C12N2710/16351—Methods of production or purification of viral material
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/16011—Herpesviridae
- C12N2710/16711—Varicellovirus, e.g. human herpesvirus 3, Varicella Zoster, pseudorabies
- C12N2710/16734—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/16011—Herpesviridae
- C12N2710/16711—Varicellovirus, e.g. human herpesvirus 3, Varicella Zoster, pseudorabies
- C12N2710/16751—Methods of production or purification of viral material

Landscapes

Life Sciences & Earth Sciences (AREA)
Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Virology (AREA)
General Health & Medical Sciences (AREA)
Immunology (AREA)
Medicinal Chemistry (AREA)
Microbiology (AREA)
Public Health (AREA)
Zoology (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Mycology (AREA)
Veterinary Medicine (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Organic Chemistry (AREA)
Epidemiology (AREA)
Genetics & Genomics (AREA)
Wood Science & Technology (AREA)
Biotechnology (AREA)
Biochemistry (AREA)
General Engineering & Computer Science (AREA)
Biomedical Technology (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Medicinal Preparation (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)

IE203/74A 1973-02-09 1974-02-04 Stable viral preparations IE38825B1 (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US330912A US3915794A (en)	1973-02-09	1973-02-09	Stabilizing compositions for cell-free viruses and cell-free virus preparations containing them

Publications (2)

Publication Number	Publication Date
IE38825L IE38825L (en)	1974-08-09
IE38825B1 true IE38825B1 (en)	1978-06-07

Family

ID=23291840

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IE203/74A IE38825B1 (en)	1973-02-09	1974-02-04	Stable viral preparations

Country Status (18)

Country	Link
US (1)	US3915794A (2)
JP (1)	JPS5732043B2 (2)
AT (1)	AT331398B (2)
BE (1)	BE810555A (2)
CA (1)	CA1035700A (2)
CH (1)	CH592143A5 (2)
DD (1)	DD110306A5 (2)
DE (1)	DE2406167C2 (2)
DK (1)	DK134032B (2)
ES (1)	ES422961A1 (2)
FR (1)	FR2216997B1 (2)
GB (1)	GB1452344A (2)
HU (1)	HU169120B (2)
IE (1)	IE38825B1 (2)
IL (1)	IL44011A (2)
NL (1)	NL178013C (2)
SE (1)	SE427799B (2)
ZA (1)	ZA74163B (2)

Families Citing this family (36)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPS57114527A (en) *	1979-10-29	1982-07-16	Merck & Co Inc	Vaccine stabilizer
PT71926B (en) *	1979-10-29	1982-03-31	Merck & Co Inc	Process for preparing a liquid vaccine comprising a stabilizer
US4273762A (en) *	1979-12-03	1981-06-16	Merck & Co., Inc.	Lyophilization process for live viral compositions
JPS59163313A (ja) *	1983-03-09	1984-09-14	Teijin Ltd	経鼻投与用ペプチドホルモン類組成物
ZA874625B (en) *	1986-06-30	1988-10-26	Smith Kline Rit	Stabilizers for live vaccines,process for their preparation and vaccines containing them
US4847078A (en) *	1987-01-14	1989-07-11	Arseco, Inc.	Storage stable topical composition having moisture control agent
JPH01112853U (2) *	1988-01-27	1989-07-28
IL90188A0 (en) *	1988-05-18	1989-12-15	Cryopharm Corp	Process and medium for the lyophilization of erythrocytes
US5045446A (en) *	1988-08-26	1991-09-03	Cryopharm Corporation	Lyophilization of cells
JPH05501419A (ja) *	1990-05-25	1993-03-18	コーブ　ラボラトリーズ　インコーポレイテッド	生体適合性、両親媒性ポリマー混合物中の細胞、細胞―様物質および小板の凍結乾燥法
AU2088992A (en) *	1992-05-05	1993-11-11	Research Foundation For Microbial Diseases Of Osaka University, The	Stabilized live vaccine
US5360736A (en) *	1992-06-04	1994-11-01	Merck & Co., Inc.	Process for attenuated varicella zoster virus vaccine production
RU2126269C1 (ru) *	1992-06-04	1999-02-20	Мерк Энд Ко., Инк.	Способ получения вакцины, способ получения свободной от клеток вакцины, способ культивирования клеток, питательная среда
CA2158935A1 (en) *	1993-10-12	1995-04-20	Chiron Viagene, Inc.	Methods for preserving recombinant viruses
ES2234018T3 (es) *	1996-04-26	2005-06-16	MERCK & CO., INC.	Formulaciones de vacunas de adn.
ZA973642B (en) *	1996-04-26	1997-11-25	Merck & Co Inc	DNA vaccine formulations.
US6051238A (en) *	1996-12-20	2000-04-18	Merck & Co., Inc.	Stabilizers for lyophilized mumps vaccines
US6210683B1 (en)	1997-09-05	2001-04-03	Merck & Co., Inc.	Stabilizers containing recombinant human serum albumin for live virus vaccines
US6926897B1 (en) *	1998-03-24	2005-08-09	Medigene Aktiengesellschaft	Medicament for the avoidance or treatment of papillomavirus-specific tumour
DE19812940A1 (de) *	1998-03-24	1999-10-07	Medigene Ag	Formulierung mit Papillomavirus-spezifischem Protein, seine Herstellung und Verwendung
GB9808922D0 (en) *	1998-04-24	1998-06-24	Cantab Pharmaceuticals Res Ltd	Virus preparations
US6225289B1 (en)	1998-12-10	2001-05-01	Genvec, Inc.	Methods and compositions for preserving adenoviral vectors
RU2144376C1 (ru) *	1999-06-28	2000-01-20	Всероссийский научно-исследовательский институт защиты животных	Сухая вирусвакцина против болезни марека и способ ее изготовления
RU2144378C1 (ru) *	1999-06-28	2000-01-20	Всероссийский научно-исследовательский институт защиты животных	Вирусвакцина против болезни марека и способ ее изготовления
FR2814957B1 (fr) *	2000-10-06	2002-12-20	Aventis Pasteur	Composition vaccinale et procede de stabilisation
US7013940B2 (en) *	2001-04-19	2006-03-21	Michelin Recherche Et Technique S.A.	Device for attenuating cavity noise in a tire and wheel
ATE300954T1 (de) *	2001-12-10	2005-08-15	Bavarian Nordic As	Poxvirus-enthaltende zusammensetzungen und verfahren zu ihrer herstellung
TWI398272B (zh) *	2005-03-08	2013-06-11	Intervet Int Bv	化學定義的安定劑
EP1870649A1 (en)	2006-06-20	2007-12-26	Octapharma AG	Lyophilisation targetting defined residual moisture by limited desorption energy levels
LT2741740T (lt)	2011-08-12	2017-08-10	Merial, Inc.	Biologinių produktų, ypatingai vakcinų, vakuuminis konservavimas
TWI690322B (zh)	2012-10-02	2020-04-11	法商傳斯堅公司	含病毒的調配物及其使用
EP3142486B1 (en)	2014-05-14	2026-03-11	Boehringer Ingelheim Vetmedica GmbH	Methods for freeze-drying and rehydrating biologics
AU2015357225B2 (en) *	2014-12-01	2020-04-09	Transgene Sa	Stable liquid vaccinia virus formulations
CN105999287A (zh) *	2016-07-01	2016-10-12	广东圣戈生物科技有限公司	一种疫苗稀释液及其制备方法
CA3037544C (en)	2016-10-05	2021-10-12	Zoetis Services Llc	Lyophilization methods that provide stably dehydrated protozoans for use as potent live vaccines
CN111065732A (zh)	2017-09-11	2020-04-24	Imba-莫利库尔生物技术研究所	肿瘤类器官模型

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB1292803A (en) *	1968-11-18	1972-10-11	Nat Res Dev	Improvements relating to the production of antigens
US3642574A (en) *	1970-04-29	1972-02-15	Us Agriculture	Method for producing vaccine for immunization of poultry against marek{3 s disease
US3783098A (en) *	1971-08-10	1974-01-01	Cornell Res Foundation Inc	Highly potent,viable and stable cellfree virus preparations from cells infected with cell-associated viruses and method for obtaining the same

1973
- 1973-02-09 US US330912A patent/US3915794A/en not_active Expired - Lifetime
1974
- 1974-01-09 ZA ZA740163A patent/ZA74163B/xx unknown
- 1974-01-16 IL IL44011A patent/IL44011A/en unknown
- 1974-01-17 FR FR7401572A patent/FR2216997B1/fr not_active Expired
- 1974-02-04 IE IE203/74A patent/IE38825B1/xx unknown
- 1974-02-04 CH CH151774A patent/CH592143A5/xx not_active IP Right Cessation
- 1974-02-04 CA CA191,632A patent/CA1035700A/en not_active Expired
- 1974-02-04 BE BE140507A patent/BE810555A/xx unknown
- 1974-02-06 SE SE7401554A patent/SE427799B/xx not_active IP Right Cessation
- 1974-02-06 DK DK64774A patent/DK134032B/da not_active IP Right Cessation
- 1974-02-06 ES ES422961A patent/ES422961A1/es not_active Expired
- 1974-02-07 JP JP1581474A patent/JPS5732043B2/ja not_active Expired
- 1974-02-07 AT AT98274A patent/AT331398B/de not_active IP Right Cessation
- 1974-02-07 GB GB559574A patent/GB1452344A/en not_active Expired
- 1974-02-08 DE DE2406167A patent/DE2406167C2/de not_active Expired
- 1974-02-08 DD DD17647674A patent/DD110306A5/xx unknown
- 1974-02-08 HU HURE000547 patent/HU169120B/hu not_active IP Right Cessation
- 1974-02-08 NL NLAANVRAGE7401786,A patent/NL178013C/xx not_active IP Right Cessation

Also Published As

Publication number	Publication date
DK134032B (da)	1976-08-30
HU169120B (2)	1976-09-28
DD110306A5 (2)	1974-12-12
IL44011A0 (en)	1974-05-16
GB1452344A (en)	1976-10-13
DE2406167A1 (de)	1974-08-15
BE810555A (fr)	1974-08-05
CA1035700A (en)	1978-08-01
IL44011A (en)	1977-04-29
US3915794A (en)	1975-10-28
IE38825L (en)	1974-08-09
AU6486574A (en)	1975-07-24
AT331398B (de)	1976-08-25
JPS49109518A (2)	1974-10-18
ZA74163B (en)	1974-11-27
DK134032C (2)	1977-02-07
FR2216997A1 (2)	1974-09-06
FR2216997B1 (2)	1978-01-06
SE427799B (sv)	1983-05-09
ES422961A1 (es)	1976-06-01
JPS5732043B2 (2)	1982-07-08
NL7401786A (2)	1974-08-13
ATA98274A (de)	1975-11-15
CH592143A5 (2)	1977-10-14
NL178013C (nl)	1986-01-02
NL178013B (nl)	1985-08-01
DE2406167C2 (de)	1984-12-20

Publication	Publication Date	Title
IE38825L (en)	1974-08-09	Stabile viral preparation
DE2861729D1 (en)	1982-05-19	Aliphatic derivatives of phosphonoformic acid, pharmaceutical compositions and methods for combating virus infections
IE802225L (en)	1981-04-29	Vaccine stabilizer
ES8505545A1 (es)	1985-06-01	Un procedimiento para producir un preparado de gamma-interferon estable
AU501876B2 (en)	1979-07-05	Improving the coldwater solubility of tea, using tannase
IE781880L (en)	1979-03-19	Immunogenic herpes virus subunit
IL45322A0 (en)	1974-10-22	Phenoxypropionic acid derivatives,the preparation thereof,and compositions containing them
CA1027563A (en)	1978-03-07	Phenothiazine derivatives, compositions thereof and methods of preparation thereof
IE40924B1 (en)	1979-09-12	Bovine adenovirus vaccines, preparation thereof and method of vaccination using them
AU506992B2 (en)	1980-01-31	Preparation of Phenolic N, N-Disubstituted Carbamate Eaters
CA961410A (en)	1975-01-21	Live attenuated infectious bovine rhinotracheitis virus vaccines and preparation thereof
IE43990L (en)	1977-05-30	Ascorbic acid preparations
IE40221B1 (en)	1979-04-11	Influenza vaccines
BE821175A (fr)	1975-04-17	Preparation de vaccins a fragments de virus apyretogenes
NL7605984A (nl)	1976-12-14	Werkwijze voor de bereiding van antimicrobisch werkzame preparaten, dergelijke preparaten en werkwijze voor de bereiding van de werkzame ver- bindingen.
AU473436B2 (en)	1976-06-24	Stable virus preparations
AU482558B2 (en)	1975-07-24	Stabilizing compositions for cell-free viruses and cell-free virus preparations containing them
IL49233A (en)	1978-08-31	O-aminoethyl dichlorophenyl ketoximes, their preparation and pharmaceutical compositions containing them
CA960586A (en)	1975-01-07	Infectious bovine rhinotracheitis virus vaccine and method of preparing and using the same
AU456693B2 (en)	1974-12-09	Improvements; in virus vaccines
JPS523890A (en)	1977-01-12	Preparation of stabilized enzymes by micro capsulation
AU486934B2 (en)	1975-05-29	Live attenuated infectious bovine rhinotracheitis virus vaccines and preparation thereof
AU457758B2 (en)	1973-06-07	Infectious bovine rhinotracheitis virus vaccine and method of preparing and using thesame
AU481547B2 (en)	1976-02-19	Phenoxypropionic acid derivatives the preparation thereof, and compositions containing them
AU3626071A (en)	1973-06-07	Infectious bovine rhinotracheitis virus vaccine and method of preparing and using thesame