IE39172L - Local anaesthetic composition - Google Patents
Local anaesthetic compositionInfo
- Publication number
- IE39172L IE39172L IE740522A IE52274A IE39172L IE 39172 L IE39172 L IE 39172L IE 740522 A IE740522 A IE 740522A IE 52274 A IE52274 A IE 52274A IE 39172 L IE39172 L IE 39172L
- Authority
- IE
- Ireland
- Prior art keywords
- diisopropylaminoethoxybutyrophenone
- volume
- local anaesthetic
- anaesthetic composition
- composition
- Prior art date
Links
- 230000003444 anaesthetic effect Effects 0.000 title 1
- UXAWFWFJXIANHZ-UHFFFAOYSA-N 1-[2-[2-[di(propan-2-yl)amino]ethoxy]phenyl]butan-1-one Chemical compound CCCC(=O)C1=CC=CC=C1OCCN(C(C)C)C(C)C UXAWFWFJXIANHZ-UHFFFAOYSA-N 0.000 abstract 3
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 abstract 3
- KFZMGEQAYNKOFK-UHFFFAOYSA-N Isopropanol Chemical compound CC(C)O KFZMGEQAYNKOFK-UHFFFAOYSA-N 0.000 abstract 2
- 206010002091 Anaesthesia Diseases 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 230000037005 anaesthesia Effects 0.000 abstract 1
- 238000001949 anaesthesia Methods 0.000 abstract 1
- 239000007864 aqueous solution Substances 0.000 abstract 1
- 230000005923 long-lasting effect Effects 0.000 abstract 1
- 238000002360 preparation method Methods 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 230000000699 topical effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Dermatology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
- Cosmetics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
o-Diisopropylaminoethoxybutyrophenone is prepared by treating an aqueous solution of an acid addition salt of o-diisopropylaminoethoxybutyrophenone with a base. Preparations of o-diisopropylaminoethoxybutyrophenone in which it is present to at least 1 % by volume, together with 40 to 70 % by volume of isopropanol and up to 40 % by volume of glycerol, produce a deep and long-lasting anaesthesia on topical application to uninjured skin.
[GB1464975A]
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE7303452A SE387536B (en) | 1973-03-13 | 1973-03-13 | PROCEDURE FOR PREPARING A LOCAL AESTHETIC PREPARATION |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IE39172L true IE39172L (en) | 1974-09-13 |
| IE39172B1 IE39172B1 (en) | 1978-08-16 |
Family
ID=20316881
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IE522/74A IE39172B1 (en) | 1973-03-13 | 1974-03-12 | Composition having local anesthetic effect |
Country Status (17)
| Country | Link |
|---|---|
| JP (1) | JPS49124219A (en) |
| AT (1) | AT333965B (en) |
| BE (1) | BE812230A (en) |
| CA (1) | CA1042798A (en) |
| CH (1) | CH608783A5 (en) |
| DD (1) | DD113694A5 (en) |
| DE (1) | DE2410939A1 (en) |
| DK (1) | DK136179B (en) |
| FI (1) | FI53068C (en) |
| FR (1) | FR2221143B1 (en) |
| GB (1) | GB1464975A (en) |
| HU (1) | HU167892B (en) |
| IE (1) | IE39172B1 (en) |
| NL (1) | NL7403079A (en) |
| SE (1) | SE387536B (en) |
| SU (1) | SU556718A3 (en) |
| ZA (1) | ZA741093B (en) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2163956B (en) * | 1984-09-08 | 1988-03-30 | Ile De France | Percutaneous anaesthetic composition for topical application |
| US6866844B2 (en) | 2002-11-07 | 2005-03-15 | Biomarin Pharmaceutical Inc. | Precursor N-acetylgalactosamine-4-sulfatase, methods of treatment using said enzyme and methods for producing and purifying said enzyme |
| EP1603542A1 (en) | 2003-03-14 | 2005-12-14 | Epistem Limited | Treatment and/or prevention of non-viral epithelial damage |
| GB0803054D0 (en) | 2008-02-20 | 2008-03-26 | Univ Manchester | Medicament |
| GB0915315D0 (en) | 2009-09-03 | 2009-10-07 | Univ Manchester | Use of non-digestible oligosaccharides |
-
1973
- 1973-03-13 SE SE7303452A patent/SE387536B/en unknown
-
1974
- 1974-02-19 ZA ZA00741093A patent/ZA741093B/en unknown
- 1974-03-04 AT AT172774A patent/AT333965B/en not_active IP Right Cessation
- 1974-03-05 CH CH743065A patent/CH608783A5/en not_active IP Right Cessation
- 1974-03-05 FI FI648/74A patent/FI53068C/fi active
- 1974-03-07 DE DE2410939A patent/DE2410939A1/en active Pending
- 1974-03-07 NL NL7403079A patent/NL7403079A/xx not_active Application Discontinuation
- 1974-03-08 GB GB1056874A patent/GB1464975A/en not_active Expired
- 1974-03-08 DD DD177059A patent/DD113694A5/xx unknown
- 1974-03-11 SU SU2004199A patent/SU556718A3/en active
- 1974-03-11 HU HUAA766A patent/HU167892B/hu unknown
- 1974-03-12 FR FR7408407A patent/FR2221143B1/fr not_active Expired
- 1974-03-12 DK DK133574AA patent/DK136179B/en unknown
- 1974-03-12 IE IE522/74A patent/IE39172B1/en unknown
- 1974-03-12 JP JP49027773A patent/JPS49124219A/ja active Pending
- 1974-03-12 CA CA194,662A patent/CA1042798A/en not_active Expired
- 1974-03-13 BE BE141943A patent/BE812230A/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| HU167892B (en) | 1976-01-28 |
| SE387536B (en) | 1976-09-13 |
| AU6623674A (en) | 1975-09-04 |
| NL7403079A (en) | 1974-09-17 |
| DD113694A5 (en) | 1975-06-20 |
| FI53068C (en) | 1978-02-10 |
| GB1464975A (en) | 1977-02-16 |
| DE2410939A1 (en) | 1974-09-19 |
| IE39172B1 (en) | 1978-08-16 |
| AT333965B (en) | 1976-12-27 |
| BE812230A (en) | 1974-09-13 |
| DK136179C (en) | 1978-03-13 |
| JPS49124219A (en) | 1974-11-28 |
| FR2221143A1 (en) | 1974-10-11 |
| ZA741093B (en) | 1975-01-29 |
| FR2221143B1 (en) | 1977-04-15 |
| DK136179B (en) | 1977-08-29 |
| ATA172774A (en) | 1976-04-15 |
| SU556718A3 (en) | 1977-04-30 |
| CA1042798A (en) | 1978-11-21 |
| CH608783A5 (en) | 1979-01-31 |
| FI53068B (en) | 1977-10-31 |
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