IE39221L - Quinoline compounds. - Google Patents
Quinoline compounds.Info
- Publication number
- IE39221L IE39221L IE740826A IE82674A IE39221L IE 39221 L IE39221 L IE 39221L IE 740826 A IE740826 A IE 740826A IE 82674 A IE82674 A IE 82674A IE 39221 L IE39221 L IE 39221L
- Authority
- IE
- Ireland
- Prior art keywords
- april
- quinoline compounds
- gb1416849a
- trifluoromethylquinoline
- morpholinoethanol
- Prior art date
Links
- 125000002943 quinolinyl group Chemical class N1=C(C=CC2=CC=CC=C12)* 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- 239000002253 acid Substances 0.000 abstract 1
- 230000000202 analgesic effect Effects 0.000 abstract 1
- 125000002490 anilino group Chemical group [H]N(*)C1=C([H])C([H])=C([H])C([H])=C1[H] 0.000 abstract 1
- 230000003110 anti-inflammatory effect Effects 0.000 abstract 1
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- 125000003754 ethoxycarbonyl group Chemical group C(=O)(OCC)* 0.000 abstract 1
- 150000004702 methyl esters Chemical class 0.000 abstract 1
- 238000007911 parenteral administration Methods 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 230000000699 topical effect Effects 0.000 abstract 1
- 238000005809 transesterification reaction Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/38—Nitrogen atoms
- C07D215/42—Nitrogen atoms attached in position 4
- C07D215/44—Nitrogen atoms attached in position 4 with aryl radicals attached to said nitrogen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
1416849 4 - [2<SP>1 </SP>- (# - Morpholino)ethoxycarbonyl]phenylamino - 8 - trifluoromethylquinoline ROUSSEL UCLAF 10 April 1974 [18 April 1973] 15940/74 Addition to 1234490 Heading C2C The novel title compound and acid addition salts thereof are prepared by transesterification of the methyl ester with #-morpholinoethanol optionally followed by salt formation. Pharmaceutical compositions in conventional forms for topical, oral, rectal or parenteral administration and having analgesic and antiinflammatory activity comprise an above novel compound and a carrier therefor.
[GB1416849A]
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR7314132A FR2226164B2 (en) | 1973-04-18 | 1973-04-18 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IE39221L true IE39221L (en) | 1974-10-18 |
| IE39221B1 IE39221B1 (en) | 1978-08-30 |
Family
ID=9118185
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IE826/74A IE39221B1 (en) | 1973-04-18 | 1974-04-17 | Esters of-4 8-trifluoromethyl quinoline |
Country Status (7)
| Country | Link |
|---|---|
| BE (1) | BE813756A (en) |
| CA (1) | CA1016547A (en) |
| DE (1) | DE2418262A1 (en) |
| FR (1) | FR2226164B2 (en) |
| GB (1) | GB1416849A (en) |
| IE (1) | IE39221B1 (en) |
| IL (1) | IL44609A (en) |
-
1973
- 1973-04-18 FR FR7314132A patent/FR2226164B2/fr not_active Expired
-
1974
- 1974-04-05 CA CA197,112A patent/CA1016547A/en not_active Expired
- 1974-04-10 GB GB1594074A patent/GB1416849A/en not_active Expired
- 1974-04-11 IL IL44609A patent/IL44609A/en unknown
- 1974-04-16 DE DE2418262A patent/DE2418262A1/en not_active Withdrawn
- 1974-04-16 BE BE143232A patent/BE813756A/en unknown
- 1974-04-17 IE IE826/74A patent/IE39221B1/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| FR2226164B2 (en) | 1976-05-14 |
| IE39221B1 (en) | 1978-08-30 |
| IL44609A (en) | 1978-10-31 |
| BE813756A (en) | 1974-10-16 |
| DE2418262A1 (en) | 1974-11-07 |
| CA1016547A (en) | 1977-08-30 |
| IL44609A0 (en) | 1974-06-30 |
| GB1416849A (en) | 1975-12-10 |
| FR2226164A2 (en) | 1974-11-15 |
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