IE40067L - 4-oxo-2-imidazolidinylideneureas - Google Patents

4-oxo-2-imidazolidinylideneureas

Info

Publication number
IE40067L
IE40067L IE742146A IE214674A IE40067L IE 40067 L IE40067 L IE 40067L IE 742146 A IE742146 A IE 742146A IE 214674 A IE214674 A IE 214674A IE 40067 L IE40067 L IE 40067L
Authority
IE
Ireland
Prior art keywords
denotes
hydrogen atom
radical
compounds
aryl
Prior art date
Application number
IE742146A
Other versions
IE40067B1 (en
Original Assignee
Mcneilab Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mcneilab Inc filed Critical Mcneilab Inc
Publication of IE40067L publication Critical patent/IE40067L/en
Publication of IE40067B1 publication Critical patent/IE40067B1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/88—Nitrogen atoms, e.g. allantoin

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Novel 4-oxo-2-imidazolidinylidene-ureas of the formula <IMAGE> wherein R1 denotes a hydrogen atom or a lower alkyl radical, R2 denotes a hydrogen atom or a lower alkyl radical, R3 denotes a hydrogen atom or an aryl radical, R4 denotes a hydrogen atom, an aryl radical or an arylalkyl radical and Ar denotes an aryl radical, with the exception of compounds in which R3 and R4 represent 2,6-disubstituted aryl radicals, are prepared. These compounds are obtained by reacting a correspondingly substituted 2-iminoimidazolidin-4-one with an arylisocyanate in an inert aprotic organic solvent. The novel compounds exert an inhibiting action on the secretion of gastric juices and a damping (suppressing) action on the central nervous system. [GB1479909A]
IE2146/74A 1973-10-19 1974-10-18 4-oxo-2-imidazolidinylideneureas IE40067B1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US40802273A 1973-10-19 1973-10-19
US50879574A 1974-09-23 1974-09-23

Publications (2)

Publication Number Publication Date
IE40067L true IE40067L (en) 1975-04-19
IE40067B1 IE40067B1 (en) 1979-02-28

Family

ID=27020109

Family Applications (1)

Application Number Title Priority Date Filing Date
IE2146/74A IE40067B1 (en) 1973-10-19 1974-10-18 4-oxo-2-imidazolidinylideneureas

Country Status (22)

Country Link
JP (1) JPS5077367A (en)
AR (1) AR210320A1 (en)
AT (1) AT348536B (en)
BE (1) BE821099A (en)
CA (1) CA1043339A (en)
CH (1) CH614198A5 (en)
DD (1) DD114079A5 (en)
DE (1) DE2448869A1 (en)
DK (1) DK548874A (en)
ES (1) ES431153A1 (en)
FI (1) FI59993C (en)
FR (1) FR2248042B1 (en)
GB (1) GB1479909A (en)
HU (1) HU170857B (en)
IE (1) IE40067B1 (en)
IL (1) IL45865A (en)
IN (1) IN139447B (en)
NL (1) NL7413718A (en)
NO (1) NO141162C (en)
RO (1) RO64926A (en)
SE (1) SE414173B (en)
YU (1) YU36932B (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI800559A7 (en) * 1979-03-14 1981-01-01 F Hoffmann La Roche & Co Urea derivatives.
US4265900A (en) * 1979-10-29 1981-05-05 Mcneilab, Inc. N-Aryl-N'-imidazol-2-ylureas
PT1699455E (en) * 2003-12-15 2013-08-27 Merck Sharp & Dohme Heterocyclic aspartyl protease inhibitors
US20140371283A1 (en) 2013-02-12 2014-12-18 Buck Institute For Research On Aging Hydantoins that modulate bace-mediated app processing

Also Published As

Publication number Publication date
DE2448869A1 (en) 1975-09-04
IL45865A0 (en) 1975-02-10
FR2248042A1 (en) 1975-05-16
NO141162B (en) 1979-10-15
FI306574A7 (en) 1975-04-20
FR2248042B1 (en) 1978-07-21
ES431153A1 (en) 1977-02-01
RO64926A (en) 1980-01-15
IL45865A (en) 1978-01-31
SE414173B (en) 1980-07-14
DD114079A5 (en) 1975-07-12
DK548874A (en) 1975-07-07
JPS5077367A (en) 1975-06-24
CA1043339A (en) 1978-11-28
AT348536B (en) 1979-02-26
FI59993B (en) 1981-07-31
IN139447B (en) 1976-06-19
FI59993C (en) 1981-11-10
BE821099A (en) 1975-04-15
CH614198A5 (en) 1979-11-15
IE40067B1 (en) 1979-02-28
NO743771L (en) 1975-05-20
GB1479909A (en) 1977-07-13
AR210320A1 (en) 1977-07-29
YU36932B (en) 1984-08-31
AU7443874A (en) 1976-04-29
NO141162C (en) 1980-01-23
YU279774A (en) 1982-06-18
ATA840974A (en) 1978-07-15
SE7412959L (en) 1975-04-21
NL7413718A (en) 1975-04-22
HU170857B (en) 1977-09-28

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