IE40139L - Aspirin tea coprecipitates - Google Patents
Aspirin tea coprecipitatesInfo
- Publication number
- IE40139L IE40139L IE731867A IE186773A IE40139L IE 40139 L IE40139 L IE 40139L IE 731867 A IE731867 A IE 731867A IE 186773 A IE186773 A IE 186773A IE 40139 L IE40139 L IE 40139L
- Authority
- IE
- Ireland
- Prior art keywords
- tea
- aspirin
- coprecipitate
- oct
- solubilized
- Prior art date
Links
- 241001122767 Theaceae Species 0.000 title abstract 6
- BSYNRYMUTXBXSQ-UHFFFAOYSA-N Aspirin Chemical compound CC(=O)OC1=CC=CC=C1C(O)=O BSYNRYMUTXBXSQ-UHFFFAOYSA-N 0.000 title abstract 3
- 229960001138 acetylsalicylic acid Drugs 0.000 title abstract 3
- 235000013616 tea Nutrition 0.000 abstract 6
- QTBSBXVTEAMEQO-UHFFFAOYSA-N Acetic acid Chemical compound CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 abstract 2
- HEDRZPFGACZZDS-UHFFFAOYSA-N Chloroform Chemical compound ClC(Cl)Cl HEDRZPFGACZZDS-UHFFFAOYSA-N 0.000 abstract 2
- MHAJPDPJQMAIIY-UHFFFAOYSA-N Hydrogen peroxide Chemical compound OO MHAJPDPJQMAIIY-UHFFFAOYSA-N 0.000 abstract 2
- CDBYLPFSWZWCQE-UHFFFAOYSA-L Sodium Carbonate Chemical compound [Na+].[Na+].[O-]C([O-])=O CDBYLPFSWZWCQE-UHFFFAOYSA-L 0.000 abstract 2
- RYYVLZVUVIJVGH-UHFFFAOYSA-N caffeine Chemical compound CN1C(=O)N(C)C(=O)C2=C1N=CN2C RYYVLZVUVIJVGH-UHFFFAOYSA-N 0.000 abstract 2
- 239000006071 cream Substances 0.000 abstract 2
- 235000020344 instant tea Nutrition 0.000 abstract 2
- 239000000203 mixture Substances 0.000 abstract 2
- NWUYHJFMYQTDRP-UHFFFAOYSA-N 1,2-bis(ethenyl)benzene;1-ethenyl-2-ethylbenzene;styrene Chemical compound C=CC1=CC=CC=C1.CCC1=CC=CC=C1C=C.C=CC1=CC=CC=C1C=C NWUYHJFMYQTDRP-UHFFFAOYSA-N 0.000 abstract 1
- 206010053155 Epigastric discomfort Diseases 0.000 abstract 1
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 abstract 1
- LPHGQDQBBGAPDZ-UHFFFAOYSA-N Isocaffeine Natural products CN1C(=O)N(C)C(=O)C2=C1N(C)C=N2 LPHGQDQBBGAPDZ-UHFFFAOYSA-N 0.000 abstract 1
- 241000287433 Turdus Species 0.000 abstract 1
- 229960000583 acetic acid Drugs 0.000 abstract 1
- 239000000654 additive Substances 0.000 abstract 1
- 230000003110 anti-inflammatory effect Effects 0.000 abstract 1
- 229960001948 caffeine Drugs 0.000 abstract 1
- VJEONQKOZGKCAK-UHFFFAOYSA-N caffeine Natural products CN1C(=O)N(C)C(=O)C2=C1C=CN2C VJEONQKOZGKCAK-UHFFFAOYSA-N 0.000 abstract 1
- 239000000969 carrier Substances 0.000 abstract 1
- 239000003729 cation exchange resin Substances 0.000 abstract 1
- 239000000470 constituent Substances 0.000 abstract 1
- 238000001816 cooling Methods 0.000 abstract 1
- 238000000605 extraction Methods 0.000 abstract 1
- 239000012362 glacial acetic acid Substances 0.000 abstract 1
- 229910021645 metal ion Inorganic materials 0.000 abstract 1
- 239000007935 oral tablet Substances 0.000 abstract 1
- 230000003647 oxidation Effects 0.000 abstract 1
- 238000007254 oxidation reaction Methods 0.000 abstract 1
- 239000002244 precipitate Substances 0.000 abstract 1
- 229910052708 sodium Inorganic materials 0.000 abstract 1
- 239000011734 sodium Substances 0.000 abstract 1
- 229910000029 sodium carbonate Inorganic materials 0.000 abstract 1
- 235000014620 theaflavin Nutrition 0.000 abstract 1
- 235000008118 thearubigins Nutrition 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/60—Salicylic acid; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/82—Theaceae (Tea family), e.g. camellia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
- A61K9/148—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with compounds of unknown constitution, e.g. material from plants or animals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Botany (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Alternative & Traditional Medicine (AREA)
- Zoology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Organic Chemistry (AREA)
- Biotechnology (AREA)
- Medical Informatics (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Medicines Containing Plant Substances (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Tea And Coffee (AREA)
Abstract
1391747 Aspirin and tea composition A H ROBINS CO INC 23 Oct 1973 [25 Oct 1972 10 Oct 1973] 49387/73 Heading A5B An anti-inflammatory composition which does not cause gastric irritation comprises a coprecipitate of 85-95% aspirin and 2-15% of a tea constituent. The coprecipitate may be prepared from a solution of tea, instant tea or solubilized tea cream in aqueous sodium carbonate by addition of glacial acetic acid. Instant tea may be decaffeinated before use by extraction with chloroform. Undesirable metal ions may be replaced by sodium on a cation exchange resin. Tea cream is the precipitate formed on cooling hot filtered tea. It contains caffeine, theaflavins and thearubigins. It is solubilized by oxidation with hydrogen peroxide. The coprecipitate may be compounded with conventional additives and carriers and made up as oral tablets.
[GB1391747A]
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US30079672A | 1972-10-25 | 1972-10-25 | |
| US40494573A | 1973-10-10 | 1973-10-10 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IE40139L true IE40139L (en) | 1974-04-25 |
| IE40139B1 IE40139B1 (en) | 1979-03-28 |
Family
ID=26971986
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IE1867/73A IE40139B1 (en) | 1972-10-25 | 1973-10-18 | Aspirin-tea coprecipitates |
Country Status (18)
| Country | Link |
|---|---|
| JP (1) | JPS5933563B2 (en) |
| AR (1) | AR199592A1 (en) |
| BE (1) | BE806392A (en) |
| CA (1) | CA1018459A (en) |
| CH (1) | CH604721A5 (en) |
| DE (1) | DE2353087C2 (en) |
| DK (1) | DK134096B (en) |
| ES (1) | ES419913A1 (en) |
| FI (1) | FI51428C (en) |
| FR (1) | FR2204415B1 (en) |
| GB (1) | GB1391747A (en) |
| IE (1) | IE40139B1 (en) |
| IL (2) | IL43512A0 (en) |
| IN (1) | IN139752B (en) |
| NL (1) | NL176142C (en) |
| NO (1) | NO140748C (en) |
| PH (1) | PH12248A (en) |
| SE (1) | SE423487B (en) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS54122259A (en) * | 1978-03-13 | 1979-09-21 | Kyowa Hakko Kogyo Co Ltd | Aluminum acetylsalicylate glutaminate |
| DE3603576A1 (en) * | 1986-02-06 | 1987-08-13 | Code Kaffee Handel | USE OF TANNING SUBSTANCES AND / OR CHLOROIC ACID AND FOOD, ENJOYMENT AND / OR MEDICINAL PRODUCTS WITH ADDITIVES OF TANNING AGENT AND / OR CHLOROGENIC ACID |
| DE102006004912A1 (en) | 2006-01-20 | 2007-07-26 | Rheinmetall Waffe Munition Gmbh | System for protection, especially of large flying platforms against infrared or radar guided missiles or other threats, has user unit with system operating elements |
| EP2432485B1 (en) | 2009-05-19 | 2013-07-31 | Unilever PLC | Prebiotic composition |
| DE102014200045A1 (en) * | 2014-01-07 | 2015-07-09 | Ralph Nussbaum | Polyphenol conjugates |
| JP6367623B2 (en) * | 2014-07-04 | 2018-08-01 | 美紀 坂巻 | Minamata protozoan pesticide and method for producing the same |
-
1970
- 1970-10-29 IL IL43512A patent/IL43512A0/en unknown
-
1973
- 1973-10-15 CA CA183,398A patent/CA1018459A/en not_active Expired
- 1973-10-18 IE IE1867/73A patent/IE40139B1/en unknown
- 1973-10-20 IN IN2335/CAL/73A patent/IN139752B/en unknown
- 1973-10-23 SE SE7314372A patent/SE423487B/en unknown
- 1973-10-23 NL NLAANVRAGE7314546,A patent/NL176142C/en not_active IP Right Cessation
- 1973-10-23 NO NO734097A patent/NO140748C/en unknown
- 1973-10-23 BE BE136957A patent/BE806392A/en not_active IP Right Cessation
- 1973-10-23 PH PH15143A patent/PH12248A/en unknown
- 1973-10-23 GB GB4938773A patent/GB1391747A/en not_active Expired
- 1973-10-23 DE DE2353087A patent/DE2353087C2/en not_active Expired
- 1973-10-23 FR FR7337765A patent/FR2204415B1/fr not_active Expired
- 1973-10-24 FI FI733303A patent/FI51428C/en active
- 1973-10-24 ES ES419913A patent/ES419913A1/en not_active Expired
- 1973-10-24 DK DK576473AA patent/DK134096B/en unknown
- 1973-10-24 AR AR250676A patent/AR199592A1/en active
- 1973-10-24 CH CH1498073A patent/CH604721A5/xx not_active IP Right Cessation
- 1973-10-25 JP JP48119475A patent/JPS5933563B2/en not_active Expired
- 1973-10-29 IL IL43512A patent/IL43512A/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| DK134096C (en) | 1977-02-14 |
| NL7314546A (en) | 1974-04-29 |
| ES419913A1 (en) | 1976-09-01 |
| AU6172573A (en) | 1975-04-24 |
| FR2204415A1 (en) | 1974-05-24 |
| IL43512A (en) | 1976-08-31 |
| JPS5933563B2 (en) | 1984-08-16 |
| BE806392A (en) | 1974-02-15 |
| FI51428C (en) | 1977-01-10 |
| IN139752B (en) | 1976-07-24 |
| DK134096B (en) | 1976-09-13 |
| CA1018459A (en) | 1977-10-04 |
| FR2204415B1 (en) | 1976-09-03 |
| NO140748C (en) | 1979-11-07 |
| GB1391747A (en) | 1975-04-23 |
| DE2353087C2 (en) | 1984-04-26 |
| IE40139B1 (en) | 1979-03-28 |
| JPS4993519A (en) | 1974-09-05 |
| NL176142C (en) | 1985-03-01 |
| NL176142B (en) | 1984-10-01 |
| FI51428B (en) | 1976-09-30 |
| DE2353087A1 (en) | 1974-05-09 |
| PH12248A (en) | 1978-12-12 |
| AR199592A1 (en) | 1974-09-13 |
| NO140748B (en) | 1979-07-30 |
| CH604721A5 (en) | 1978-09-15 |
| IL43512A0 (en) | 1974-03-14 |
| SE423487B (en) | 1982-05-10 |
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