IE40344L - Opthalmic and otic preparations - Google Patents
Opthalmic and otic preparationsInfo
- Publication number
- IE40344L IE40344L IE742665A IE266574A IE40344L IE 40344 L IE40344 L IE 40344L IE 742665 A IE742665 A IE 742665A IE 266574 A IE266574 A IE 266574A IE 40344 L IE40344 L IE 40344L
- Authority
- IE
- Ireland
- Prior art keywords
- opthalmic
- otic preparations
- gb1484329a
- benzylacrylonitrile
- aminoalpha
- Prior art date
Links
- 238000002360 preparation method Methods 0.000 title 1
- ZRALSGWEFCBTJO-UHFFFAOYSA-N Guanidine Chemical compound NC(N)=N ZRALSGWEFCBTJO-UHFFFAOYSA-N 0.000 abstract 2
- JIEUKCKMTDJTEK-UHFFFAOYSA-N 3-amino-2-benzylprop-2-enenitrile Chemical class NC=C(C#N)CC1=CC=CC=C1 JIEUKCKMTDJTEK-UHFFFAOYSA-N 0.000 abstract 1
- CHJJGSNFBQVOTG-UHFFFAOYSA-N N-methyl-guanidine Natural products CNC(N)=N CHJJGSNFBQVOTG-UHFFFAOYSA-N 0.000 abstract 1
- 125000001931 aliphatic group Chemical group 0.000 abstract 1
- 125000003277 amino group Chemical group 0.000 abstract 1
- 125000003118 aryl group Chemical group 0.000 abstract 1
- SWSQBOPZIKWTGO-UHFFFAOYSA-N dimethylaminoamidine Natural products CN(C)C(N)=N SWSQBOPZIKWTGO-UHFFFAOYSA-N 0.000 abstract 1
- 125000000623 heterocyclic group Chemical group 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 125000004435 hydrogen atom Chemical class [H]* 0.000 abstract 1
- 239000000825 pharmaceutical preparation Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- SKIVFJLNDNKQPD-UHFFFAOYSA-N sulfacetamide Chemical compound CC(=O)NS(=O)(=O)C1=CC=C(N)C=C1 SKIVFJLNDNKQPD-UHFFFAOYSA-N 0.000 abstract 1
- 229960002673 sulfacetamide Drugs 0.000 abstract 1
- IEDVJHCEMCRBQM-UHFFFAOYSA-N trimethoprim Chemical compound COC1=C(OC)C(OC)=CC(CC=2C(=NC(N)=NC=2)N)=C1 IEDVJHCEMCRBQM-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Ophthalmology & Optometry (AREA)
- Virology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
2,4-Diamino-5-(3',4',5'-trimethoxybenzyl)pyrimidine, which is intended as a potentiator for sulphacetamide contained in a pharmaceutical preparation for administration to the eye or to the ear, which additionally contains polymixin in the form of a pharmaceutically acceptable salt, is prepared by reacting an appropriately substituted beta -aminoalpha -benzylacrylonitrile of the accompanying formula, in which Z denotes an aliphatic, aromatic or heterocyclic amino group -NR'R'', where R' or R'' can also denote hydrogen, with guanidine. <IMAGE>
[GB1484329A]
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US42891873A | 1973-12-27 | 1973-12-27 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IE40344L true IE40344L (en) | 1975-06-27 |
| IE40344B1 IE40344B1 (en) | 1979-05-09 |
Family
ID=23700962
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IE2665/74A IE40344B1 (en) | 1973-12-27 | 1974-12-30 | Ophthalmic and otic preparations |
Country Status (22)
| Country | Link |
|---|---|
| JP (1) | JPS5830284B2 (en) |
| AT (1) | AT345448B (en) |
| BE (1) | BE823952A (en) |
| CA (1) | CA1031263A (en) |
| CH (1) | CH616413A5 (en) |
| CY (1) | CY1103A (en) |
| DE (1) | DE2461570C3 (en) |
| DK (1) | DK684474A (en) |
| ES (1) | ES433357A1 (en) |
| FI (1) | FI374974A7 (en) |
| FR (1) | FR2255909B1 (en) |
| GB (1) | GB1484329A (en) |
| HK (1) | HK3081A (en) |
| IE (1) | IE40344B1 (en) |
| IL (1) | IL46353A (en) |
| IN (1) | IN140139B (en) |
| KE (1) | KE3103A (en) |
| MC (1) | MC1044A1 (en) |
| MY (1) | MY8400041A (en) |
| NL (1) | NL7416636A (en) |
| SE (1) | SE421996B (en) |
| ZA (1) | ZA748179B (en) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0037043B1 (en) * | 1980-03-21 | 1984-11-21 | The Wellcome Foundation Limited | Stabilised ophthalmic formulation |
| ES2079994B1 (en) * | 1992-10-07 | 1996-08-01 | Cusi Lab | PHARMACEUTICAL FORMULATION BASED ON POLYMIXINE-TRIMETOPRIM AND AN ANTI-INFLAMMATORY AGENT FOR ITS TOPICAL OPHTHALMIC AND ETHICAL USE. |
| ES2913058T3 (en) * | 2016-08-16 | 2022-05-31 | Univ Rochester | Pharmaceutical composition containing therapeutic based on polymyxin b/trimethoprim |
-
1974
- 1974-12-20 NL NL7416636A patent/NL7416636A/en not_active Application Discontinuation
- 1974-12-23 CY CY1103A patent/CY1103A/en unknown
- 1974-12-23 ZA ZA00748179A patent/ZA748179B/en unknown
- 1974-12-23 GB GB55542/74A patent/GB1484329A/en not_active Expired
- 1974-12-24 CA CA216,920A patent/CA1031263A/en not_active Expired
- 1974-12-27 SE SE7416310A patent/SE421996B/en not_active IP Right Cessation
- 1974-12-27 ES ES433357A patent/ES433357A1/en not_active Expired
- 1974-12-27 JP JP752007A patent/JPS5830284B2/en not_active Expired
- 1974-12-27 MC MC1133A patent/MC1044A1/en unknown
- 1974-12-27 IN IN2866/CAL/74A patent/IN140139B/en unknown
- 1974-12-27 FI FI3749/74A patent/FI374974A7/fi unknown
- 1974-12-27 DE DE2461570A patent/DE2461570C3/en not_active Expired
- 1974-12-27 IL IL46353A patent/IL46353A/en unknown
- 1974-12-27 AT AT1034074A patent/AT345448B/en not_active IP Right Cessation
- 1974-12-27 DK DK684474A patent/DK684474A/da not_active Application Discontinuation
- 1974-12-27 FR FR7443034A patent/FR2255909B1/fr not_active Expired
- 1974-12-27 BE BE152017A patent/BE823952A/en not_active IP Right Cessation
- 1974-12-30 IE IE2665/74A patent/IE40344B1/en unknown
- 1974-12-30 CH CH1737374A patent/CH616413A5/en not_active IP Right Cessation
-
1980
- 1980-12-10 KE KE3103A patent/KE3103A/en unknown
-
1981
- 1981-01-22 HK HK30/81A patent/HK3081A/en unknown
-
1984
- 1984-12-30 MY MY41/84A patent/MY8400041A/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| SE7416310L (en) | 1975-06-30 |
| IL46353A (en) | 1977-12-30 |
| JPS5830284B2 (en) | 1983-06-28 |
| CY1103A (en) | 1981-09-11 |
| HK3081A (en) | 1981-01-30 |
| MY8400041A (en) | 1984-12-31 |
| FI374974A7 (en) | 1975-06-29 |
| NL7416636A (en) | 1975-07-01 |
| KE3103A (en) | 1981-02-13 |
| DE2461570A1 (en) | 1975-07-10 |
| DE2461570B2 (en) | 1981-06-04 |
| AT345448B (en) | 1978-09-11 |
| DK684474A (en) | 1975-09-08 |
| MC1044A1 (en) | 1975-10-10 |
| CH616413A5 (en) | 1980-03-31 |
| ES433357A1 (en) | 1977-04-01 |
| JPS5095418A (en) | 1975-07-29 |
| DE2461570C3 (en) | 1982-05-19 |
| FR2255909A1 (en) | 1975-07-25 |
| IL46353A0 (en) | 1975-04-25 |
| IE40344B1 (en) | 1979-05-09 |
| ZA748179B (en) | 1976-07-28 |
| CA1031263A (en) | 1978-05-16 |
| IN140139B (en) | 1976-09-18 |
| BE823952A (en) | 1975-06-27 |
| ATA1034074A (en) | 1978-01-15 |
| AU7696174A (en) | 1976-07-01 |
| SE421996B (en) | 1982-02-15 |
| GB1484329A (en) | 1977-09-01 |
| FR2255909B1 (en) | 1978-06-30 |
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