IE41368L - Sulphoglycopeptides from milk as therapeutic agents - Google Patents

Sulphoglycopeptides from milk as therapeutic agents

Info

Publication number
IE41368L
IE41368L IE751190A IE119075A IE41368L IE 41368 L IE41368 L IE 41368L IE 751190 A IE751190 A IE 751190A IE 119075 A IE119075 A IE 119075A IE 41368 L IE41368 L IE 41368L
Authority
IE
Ireland
Prior art keywords
sulphoglycopeptides
sulphoglycopeptide
milk
resulting
glycopeptide
Prior art date
Application number
IE751190A
Other versions
IE41368B1 (en
Original Assignee
Crinos Industria Farmaco
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Crinos Industria Farmaco filed Critical Crinos Industria Farmaco
Publication of IE41368L publication Critical patent/IE41368L/en
Publication of IE41368B1 publication Critical patent/IE41368B1/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4732Casein
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K1/00General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14Extraction; Separation; Purification
    • C07K1/145Extraction; Separation; Purification by extraction or solubilisation
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Analytical Chemistry (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)

Abstract

1448660 Sulphoglycopeptides CRINOS INDUSTRIA FARMACOBIOLOGICA SpA 23 May 1975 [30 May 1974] 22932/75 Heading C3H Starting from amixture of a glycopeptide extracted from milk or casein, (b) an aprotic, non-aromatic, water-miscible solvent (c) a tertiary base having a boiling point of from 100-250‹ C. and (d) a sulphonating agent selected from sulphuric acid, oleum, chlorosulphonic acid and an adduct of sulphur tinoxide and an organic compound, sulphoglycopeptides are made by maintaining an initial temperature at contact between the glycopeptide and the sulphonating agent of from about - 20‹ to 20‹ C., raising the temperature to a range of from about 60‹ C. to about 90‹ C. and recovering the resulting sulphoglycopeptide. If desired the resulting sulphoglycopeptide may be further reacted with an alkali metal or alkaline earth metal hydroxide or ammonium hydroxide to convert the sulphoglycopeptide to its corresponding salt which may thereafter be precipiaated by addition of acetone on methanol. Such salts may be ionexchanged with Zn<SP>++</SP>, Ca<SP>++</SP>, Ba<SP>++</SP>, Sr<SP>++</SP>, Cu<SP>++</SP>, Ni<SP>++</SP>, Co<SP>++</SP>, Mg<SP>++</SP>, Bi<SP>++</SP>, Au<SP>+</SP> or Al<SP>+++</SP> by passage through a cation exchange resin. [GB1448660A]
IE1190/75A 1974-05-30 1975-05-28 Sulfoderivatives of glycopeptides extracted from milk or caseins useful as drugs and process for their preparation IE41368B1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT23359/74A IT1037058B (en) 1974-05-30 1974-05-30 SULFODERIVATES OF GLOCOPEPTIDES EXTRACTS FROM MILK USEFUL AS MEDICATIONS AND PROCEDURE FOR THEIR PREPARATION

Publications (2)

Publication Number Publication Date
IE41368L true IE41368L (en) 1975-11-30
IE41368B1 IE41368B1 (en) 1979-12-19

Family

ID=11206381

Family Applications (1)

Application Number Title Priority Date Filing Date
IE1190/75A IE41368B1 (en) 1974-05-30 1975-05-28 Sulfoderivatives of glycopeptides extracted from milk or caseins useful as drugs and process for their preparation

Country Status (23)

Country Link
JP (1) JPS5111718A (en)
AR (1) AR205198A1 (en)
AT (1) AT354649B (en)
BE (1) BE828960A (en)
CA (1) CA1033720A (en)
CH (1) CH605681A5 (en)
DE (1) DE2523432A1 (en)
DK (1) DK232175A (en)
ES (1) ES438034A1 (en)
FR (1) FR2273007A1 (en)
GB (1) GB1448660A (en)
IE (1) IE41368B1 (en)
IL (1) IL47382A0 (en)
IN (1) IN139132B (en)
IT (1) IT1037058B (en)
LU (1) LU72601A1 (en)
MY (1) MY7700284A (en)
NL (1) NL7506382A (en)
NO (1) NO751908L (en)
PL (1) PL94775B1 (en)
RO (1) RO72709A (en)
SE (1) SE7506121L (en)
ZA (1) ZA753456B (en)

Also Published As

Publication number Publication date
NL7506382A (en) 1975-12-02
MY7700284A (en) 1977-12-31
BE828960A (en) 1975-09-01
IE41368B1 (en) 1979-12-19
ATA378275A (en) 1979-06-15
NO751908L (en) 1975-12-02
FR2273007A1 (en) 1975-12-26
ZA753456B (en) 1976-04-28
PL94775B1 (en) 1977-08-31
AT354649B (en) 1979-01-25
LU72601A1 (en) 1975-10-08
GB1448660A (en) 1976-09-08
AU8163475A (en) 1976-12-02
JPS5111718A (en) 1976-01-30
CA1033720A (en) 1978-06-27
ES438034A1 (en) 1977-02-16
DE2523432A1 (en) 1975-12-11
DK232175A (en) 1975-12-01
RO72709A (en) 1982-02-26
IL47382A0 (en) 1976-10-31
SE7506121L (en) 1975-12-01
IN139132B (en) 1976-05-08
CH605681A5 (en) 1978-10-13
IT1037058B (en) 1979-11-10
AR205198A1 (en) 1976-04-12

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