IE41477L - Sulphonylcarbamoyl derivatives - Google Patents
Sulphonylcarbamoyl derivativesInfo
- Publication number
- IE41477L IE41477L IE751312A IE131275A IE41477L IE 41477 L IE41477 L IE 41477L IE 751312 A IE751312 A IE 751312A IE 131275 A IE131275 A IE 131275A IE 41477 L IE41477 L IE 41477L
- Authority
- IE
- Ireland
- Prior art keywords
- arylsulfonylcarbamoyl
- derivatives
- dicarbonylalicyclic
- chlorobenzenesulfonylcarbamoyl
- acyclic
- Prior art date
Links
- -1 Sulphonylcarbamoyl Chemical class 0.000 title 1
- 230000002159 abnormal effect Effects 0.000 abstract 1
- 150000001260 acyclic compounds Chemical class 0.000 abstract 1
- 125000002015 acyclic group Chemical group 0.000 abstract 1
- 239000008280 blood Substances 0.000 abstract 1
- 210000004369 blood Anatomy 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 230000003345 hyperglycaemic effect Effects 0.000 abstract 1
- 230000002218 hypoglycaemic effect Effects 0.000 abstract 1
- QLXKYKBCVAABLB-UHFFFAOYSA-N n-(4-chlorophenyl)sulfonyl-2,6-dioxo-4-pentan-3-ylcyclohexane-1-carboxamide Chemical compound O=C1CC(C(CC)CC)CC(=O)C1C(=O)NS(=O)(=O)C1=CC=C(Cl)C=C1 QLXKYKBCVAABLB-UHFFFAOYSA-N 0.000 abstract 1
- XAPKRXDEHGLXGL-UHFFFAOYSA-N n-(4-chlorophenyl)sulfonyl-4,4-dimethyl-2,6-dioxocyclohexane-1-carboxamide Chemical compound O=C1CC(C)(C)CC(=O)C1C(=O)NS(=O)(=O)C1=CC=C(Cl)C=C1 XAPKRXDEHGLXGL-UHFFFAOYSA-N 0.000 abstract 1
- 239000000376 reactant Substances 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/18—Sulfonamides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
- C07C311/50—Compounds containing any of the groups, X being a hetero atom, Y being any atom
- C07C311/52—Y being a hetero atom
- C07C311/53—X and Y not being nitrogen atoms, e.g. N-sulfonylcarbamic acid
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
- C07C311/50—Compounds containing any of the groups, X being a hetero atom, Y being any atom
- C07C311/51—Y being a hydrogen or a carbon atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
- C07C2601/14—The ring being saturated
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
A new class of arylsulfonylcarbamoyl-1,3-cyclohexanediones and arylsulfonylcarbamoyl-1,3-dicarbonylacyclic compounds are disclosed. These substances have hypoglycemic or hyperglycemic properties and are of value in controlling abnormal blood sugar levels. The arylsulfonylcarbamoyl derivatives of 1,3-dicarbonylalicyclic and acyclic compounds are prepared by reacting an arylsulfonylisocyanate with a 1,3-dicarbonylalicyclic or acyclic reactant. Typical embodiments are 2-(N-p-chlorobenzenesulfonylcarbamoyl)-5,5-dimethylcyclohexane-1,3-dione and 5-(1-ethylpropyl)-2-(N-p-chlorobenzenesulfonylcarbamoyl)-1,3-cyclohexa nedione.
[US3917692A]
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US478497A US3917692A (en) | 1974-06-12 | 1974-06-12 | Arylsulfonylcarbamoyl-1,3-dicarbonylalicyclic |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IE41477L true IE41477L (en) | 1975-12-12 |
| IE41477B1 IE41477B1 (en) | 1980-01-16 |
Family
ID=23900189
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IE1312/75A IE41477B1 (en) | 1974-06-12 | 1975-06-11 | Sulfonylcarbamoyl derivatives |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US3917692A (en) |
| JP (1) | JPS5829785B2 (en) |
| AU (1) | AU8129175A (en) |
| BE (1) | BE829953A (en) |
| CA (1) | CA1051924A (en) |
| CH (1) | CH596158A5 (en) |
| DE (1) | DE2526195A1 (en) |
| DK (1) | DK261775A (en) |
| FR (1) | FR2274288A1 (en) |
| GB (1) | GB1454737A (en) |
| IE (1) | IE41477B1 (en) |
| LU (1) | LU72697A1 (en) |
| NL (1) | NL7506830A (en) |
| SE (1) | SE7506707L (en) |
| YU (1) | YU40265B (en) |
| ZA (1) | ZA753689B (en) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS54156826A (en) * | 1978-05-23 | 1979-12-11 | Sumitomo Electric Ind Ltd | Metod of making glass fiber for light transmission |
| US4347380A (en) * | 1979-04-20 | 1982-08-31 | Stauffer Chemical Company | N-Acylsulfonamide herbicidal antidotes |
| US5135941A (en) * | 1989-12-18 | 1992-08-04 | G. D. Searle & Co. | LTB4 synthesis inhibitors |
| AR037097A1 (en) | 2001-10-05 | 2004-10-20 | Novartis Ag | ACILSULFONAMID COMPOUNDS, PHARMACEUTICAL COMPOSITIONS AND THE USE OF SUCH COMPOUNDS FOR THE PREPARATION OF A MEDICINAL PRODUCT |
| WO2004113091A1 (en) * | 2003-06-24 | 2004-12-29 | Idemitsu Kosan Co., Ltd. | Heat-sensitive recording material and benzenesulfonamide derivative |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3298917A (en) * | 1964-09-15 | 1967-01-17 | Merck & Co Inc | Antidiabetic nu-acylaliphaticsulfonamides |
| CH475250A (en) * | 1966-08-25 | 1969-07-15 | Geigy Ag J R | Process for the preparation of new N'-substituted N-arylsulfonylureas |
-
1974
- 1974-06-12 US US478497A patent/US3917692A/en not_active Expired - Lifetime
-
1975
- 1975-05-16 AU AU81291/75A patent/AU8129175A/en not_active Expired
- 1975-05-26 CA CA227,783A patent/CA1051924A/en not_active Expired
- 1975-06-06 GB GB2445575A patent/GB1454737A/en not_active Expired
- 1975-06-06 BE BE157097A patent/BE829953A/en unknown
- 1975-06-09 ZA ZA00753689A patent/ZA753689B/en unknown
- 1975-06-09 NL NL7506830A patent/NL7506830A/en unknown
- 1975-06-10 LU LU72697A patent/LU72697A1/xx unknown
- 1975-06-10 DK DK261775A patent/DK261775A/en unknown
- 1975-06-11 FR FR7518300A patent/FR2274288A1/en active Granted
- 1975-06-11 JP JP50069778A patent/JPS5829785B2/en not_active Expired
- 1975-06-11 CH CH756575A patent/CH596158A5/xx not_active IP Right Cessation
- 1975-06-11 IE IE1312/75A patent/IE41477B1/en unknown
- 1975-06-11 SE SE7506707A patent/SE7506707L/en unknown
- 1975-06-12 YU YU1515/75A patent/YU40265B/en unknown
- 1975-06-12 DE DE19752526195 patent/DE2526195A1/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| CH596158A5 (en) | 1978-02-28 |
| US3917692A (en) | 1975-11-04 |
| CA1051924A (en) | 1979-04-03 |
| GB1454737A (en) | 1976-11-03 |
| FR2274288B1 (en) | 1978-11-10 |
| SE7506707L (en) | 1975-12-15 |
| JPS5111734A (en) | 1976-01-30 |
| AU8129175A (en) | 1976-11-25 |
| BE829953A (en) | 1975-12-08 |
| DK261775A (en) | 1975-12-13 |
| YU40265B (en) | 1985-12-31 |
| DE2526195A1 (en) | 1976-01-02 |
| ZA753689B (en) | 1976-05-26 |
| LU72697A1 (en) | 1976-04-13 |
| YU151575A (en) | 1982-06-30 |
| NL7506830A (en) | 1975-12-16 |
| FR2274288A1 (en) | 1976-01-09 |
| IE41477B1 (en) | 1980-01-16 |
| JPS5829785B2 (en) | 1983-06-24 |
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