IE41620L - Pharmaceutical preparation - Google Patents
Pharmaceutical preparationInfo
- Publication number
- IE41620L IE41620L IE750371A IE37175A IE41620L IE 41620 L IE41620 L IE 41620L IE 750371 A IE750371 A IE 750371A IE 37175 A IE37175 A IE 37175A IE 41620 L IE41620 L IE 41620L
- Authority
- IE
- Ireland
- Prior art keywords
- digoxin
- capsule
- feb
- solution
- conventional tablet
- Prior art date
Links
- 239000000825 pharmaceutical preparation Substances 0.000 title 1
- LTMHDMANZUZIPE-AMTYYWEZSA-N Digoxin Natural products O([C@H]1[C@H](C)O[C@H](O[C@@H]2C[C@@H]3[C@@](C)([C@@H]4[C@H]([C@]5(O)[C@](C)([C@H](O)C4)[C@H](C4=CC(=O)OC4)CC5)CC3)CC2)C[C@@H]1O)[C@H]1O[C@H](C)[C@@H](O[C@H]2O[C@@H](C)[C@H](O)[C@@H](O)C2)[C@@H](O)C1 LTMHDMANZUZIPE-AMTYYWEZSA-N 0.000 abstract 5
- LTMHDMANZUZIPE-PUGKRICDSA-N digoxin Chemical compound C1[C@H](O)[C@H](O)[C@@H](C)O[C@H]1O[C@@H]1[C@@H](C)O[C@@H](O[C@@H]2[C@H](O[C@@H](O[C@@H]3C[C@@H]4[C@]([C@@H]5[C@H]([C@]6(CC[C@@H]([C@@]6(C)[C@H](O)C5)C=5COC(=O)C=5)O)CC4)(C)CC3)C[C@@H]2O)C)C[C@@H]1O LTMHDMANZUZIPE-PUGKRICDSA-N 0.000 abstract 5
- 229960005156 digoxin Drugs 0.000 abstract 5
- LTMHDMANZUZIPE-UHFFFAOYSA-N digoxine Natural products C1C(O)C(O)C(C)OC1OC1C(C)OC(OC2C(OC(OC3CC4C(C5C(C6(CCC(C6(C)C(O)C5)C=5COC(=O)C=5)O)CC4)(C)CC3)CC2O)C)CC1O LTMHDMANZUZIPE-UHFFFAOYSA-N 0.000 abstract 5
- 239000002775 capsule Substances 0.000 abstract 4
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 3
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 abstract 3
- DNIAPMSPPWPWGF-UHFFFAOYSA-N Propylene glycol Chemical compound CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 abstract 3
- KFZMGEQAYNKOFK-UHFFFAOYSA-N Isopropanol Chemical compound CC(C)O KFZMGEQAYNKOFK-UHFFFAOYSA-N 0.000 abstract 2
- 239000002904 solvent Substances 0.000 abstract 2
- 239000002202 Polyethylene glycol Substances 0.000 abstract 1
- 238000004040 coloring Methods 0.000 abstract 1
- 210000001198 duodenum Anatomy 0.000 abstract 1
- 239000007903 gelatin capsule Substances 0.000 abstract 1
- 239000003605 opacifier Substances 0.000 abstract 1
- 230000001766 physiological effect Effects 0.000 abstract 1
- 239000004014 plasticizer Substances 0.000 abstract 1
- 229920001223 polyethylene glycol Polymers 0.000 abstract 1
- 239000003755 preservative agent Substances 0.000 abstract 1
- 230000002335 preservative effect Effects 0.000 abstract 1
- 210000002784 stomach Anatomy 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4858—Organic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Molecular Biology (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
1506016 Encapsulated digoxin solution WELLCOME FOUNDATION Ltd 21 Feb 1975 [22 Feb 1974 19 March 1974] 7327/75 Heading A5B An orally ingestible digoxin preparation of improved properties comprises a capsule soluble in the stomach or duodenum contaming a solution of digoxin, the amount of digoxin in the capsule being less than that in a conventional tablet but nonetheless providing the same physiological effect as the conventional tablet. The capsule may contain 0.05-0.4mg. digoxin. Solvents specified include ethanol, isopropanol, propylene glycol, glycerol and polyethylene glycol of molecular weight 190-1000. The solvent may include up to 60 % water. The capsule may be a soft gelatin capsule including a plasticizer, preservative, colouring and/or opacifier.
[GB1506016A]
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US44496174A | 1974-02-22 | 1974-02-22 | |
| US45300074A | 1974-03-19 | 1974-03-19 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IE41620L true IE41620L (en) | 1975-08-22 |
| IE41620B1 IE41620B1 (en) | 1980-02-13 |
Family
ID=27034126
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IE371/75A IE41620B1 (en) | 1974-02-22 | 1975-02-21 | Pharmaceutical preperations |
Country Status (14)
| Country | Link |
|---|---|
| JP (1) | JPS50126822A (en) |
| AU (2) | AU501549B2 (en) |
| CA (1) | CA1096307A (en) |
| DE (1) | DE2507635A1 (en) |
| ES (1) | ES434971A1 (en) |
| FI (1) | FI750489A7 (en) |
| FR (1) | FR2261752B1 (en) |
| GB (1) | GB1506016A (en) |
| IE (1) | IE41620B1 (en) |
| IL (1) | IL46682A (en) |
| IT (1) | IT1233251B (en) |
| LU (1) | LU71894A1 (en) |
| NL (1) | NL7502121A (en) |
| SE (1) | SE426549B (en) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1508770A (en) * | 1974-04-01 | 1978-04-26 | Scherer Ltd R | Pharmaceutical compositions |
| US4002718A (en) * | 1974-10-16 | 1977-01-11 | Arnar-Stone Laboratories, Inc. | Gelatin-encapsulated digoxin solutions and method of preparing the same |
| FR2380030A1 (en) * | 1977-02-09 | 1978-09-08 | Christiaens Sa A | Liquid and solid solns. of gitoxin - with high bio:availability for treating cardiac disorders |
| IT1158722B (en) * | 1977-07-08 | 1987-02-25 | Simes | PHARMACEUTICAL COMPOSITION FOR THE TREATMENT OF SLEEP TURBES |
| JPS5625428U (en) * | 1979-08-03 | 1981-03-09 | ||
| US4366145A (en) * | 1981-06-24 | 1982-12-28 | Sandoz, Inc. | Soft gelatin capsule with a liquid ergot alkaloid center fill solution and method of preparation |
| SE8203953D0 (en) * | 1982-06-24 | 1982-06-24 | Astra Laekemedel Ab | PHARMACEUTICAL MIXTURE |
| US4994260A (en) * | 1982-05-28 | 1991-02-19 | Astra Lakemedel Aktiebolag | Pharmaceutical mixture |
| DE3445237C1 (en) * | 1984-12-12 | 1986-06-05 | R.P. Scherer GmbH, 6930 Eberbach | Soft gelatin capsules and process for their manufacture |
| DE3529694A1 (en) * | 1985-08-20 | 1987-02-26 | Scherer Gmbh R P | GELATINE CAPSULES AND METHOD FOR THEIR PRODUCTION |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1481411A (en) * | 1973-07-20 | 1977-07-27 | Scherer Ltd R | Pharmaceutical compositions |
-
1975
- 1975-02-21 NL NL7502121A patent/NL7502121A/en active Search and Examination
- 1975-02-21 FR FR7505457A patent/FR2261752B1/fr not_active Expired
- 1975-02-21 SE SE7501967A patent/SE426549B/en not_active IP Right Cessation
- 1975-02-21 CA CA220,535A patent/CA1096307A/en not_active Expired
- 1975-02-21 FI FI750489A patent/FI750489A7/fi not_active Application Discontinuation
- 1975-02-21 DE DE19752507635 patent/DE2507635A1/en active Granted
- 1975-02-21 ES ES434971A patent/ES434971A1/en not_active Expired
- 1975-02-21 AU AU78440/75A patent/AU501549B2/en not_active Expired
- 1975-02-21 JP JP50021803A patent/JPS50126822A/ja active Pending
- 1975-02-21 GB GB7327/75A patent/GB1506016A/en not_active Expired
- 1975-02-21 IL IL46682A patent/IL46682A/en unknown
- 1975-02-21 IE IE371/75A patent/IE41620B1/en unknown
- 1975-02-21 LU LU71894A patent/LU71894A1/xx unknown
-
1979
- 1979-05-28 AU AU47500/79A patent/AU520082B2/en not_active Ceased
-
1983
- 1983-11-28 IT IT8349395A patent/IT1233251B/en active
Also Published As
| Publication number | Publication date |
|---|---|
| AU520082B2 (en) | 1982-01-14 |
| IT8349395A0 (en) | 1983-11-28 |
| LU71894A1 (en) | 1975-12-09 |
| ES434971A1 (en) | 1977-05-16 |
| IT1233251B (en) | 1992-03-24 |
| JPS50126822A (en) | 1975-10-06 |
| SE7501967L (en) | 1975-08-25 |
| AU501549B2 (en) | 1979-06-21 |
| DE2507635C2 (en) | 1991-07-25 |
| IL46682A0 (en) | 1975-04-25 |
| FR2261752B1 (en) | 1978-07-21 |
| CA1096307A (en) | 1981-02-24 |
| DE2507635A1 (en) | 1975-08-28 |
| FI750489A7 (en) | 1975-08-23 |
| IL46682A (en) | 1979-07-25 |
| SE426549B (en) | 1983-01-31 |
| GB1506016A (en) | 1978-04-05 |
| AU7844075A (en) | 1976-08-26 |
| IE41620B1 (en) | 1980-02-13 |
| FR2261752A1 (en) | 1975-09-19 |
| NL7502121A (en) | 1975-08-26 |
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