IE42129B1 - Compositions for remineralizing tooth enamel - Google Patents

Compositions for remineralizing tooth enamel

Info

Publication number: IE42129B1
Authority: IE; Ireland
Prior art keywords: weight; water; calcium; phosphate; salt
Prior art date: 1974-10-10

Application number

IE2027/75A

Other languages

English (en)

Other versions

IE42129L (en

Original Assignee

Procter & Gamble

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1974-10-10

Filing date

1975-09-16

Publication date

1980-06-04

1975-09-16 Application filed by Procter & Gamble filed Critical Procter & Gamble

1976-04-10 Publication of IE42129L publication Critical patent/IE42129L/xx

1980-06-04 Publication of IE42129B1 publication Critical patent/IE42129B1/en

Links

239000000203 mixture Substances 0.000 title claims abstract description 73
210000003298 dental enamel Anatomy 0.000 title claims abstract description 29
230000000395 remineralizing effect Effects 0.000 title claims abstract description 16
150000003839 salts Chemical class 0.000 claims abstract description 27
XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 27
210000000214 mouth Anatomy 0.000 claims abstract description 21
239000011575 calcium Substances 0.000 claims abstract description 19
229910052791 calcium Inorganic materials 0.000 claims abstract description 19
OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 claims abstract description 17
NBIIXXVUZAFLBC-UHFFFAOYSA-K phosphate Chemical compound [O-]P([O-])([O-])=O NBIIXXVUZAFLBC-UHFFFAOYSA-K 0.000 claims abstract description 17
239000002244 precipitate Substances 0.000 claims abstract description 17
229910052749 magnesium Inorganic materials 0.000 claims abstract description 14
239000011777 magnesium Substances 0.000 claims abstract description 14
229910001385 heavy metal Inorganic materials 0.000 claims abstract description 13
FYYHWMGAXLPEAU-UHFFFAOYSA-N Magnesium Chemical compound [Mg] FYYHWMGAXLPEAU-UHFFFAOYSA-N 0.000 claims abstract description 12
150000001450 anions Chemical class 0.000 claims abstract description 12
239000004615 ingredient Substances 0.000 claims abstract description 12
229910019142 PO4 Inorganic materials 0.000 claims abstract description 11
159000000007 calcium salts Chemical class 0.000 claims abstract description 10
239000002324 mouth wash Substances 0.000 claims abstract description 10
239000010452 phosphate Substances 0.000 claims abstract description 10
150000003013 phosphoric acid derivatives Chemical class 0.000 claims abstract description 9
KRHYYFGTRYWZRS-UHFFFAOYSA-M Fluoride anion Chemical compound [F-] KRHYYFGTRYWZRS-UHFFFAOYSA-M 0.000 claims abstract description 8
229910052738 indium Inorganic materials 0.000 claims abstract description 8
APFVFJFRJDLVQX-UHFFFAOYSA-N indium atom Chemical compound [In] APFVFJFRJDLVQX-UHFFFAOYSA-N 0.000 claims abstract description 8
150000001768 cations Chemical class 0.000 claims abstract description 7
229910052761 rare earth metal Inorganic materials 0.000 claims abstract description 7
XEEYBQQBJWHFJM-UHFFFAOYSA-N Iron Chemical compound [Fe] XEEYBQQBJWHFJM-UHFFFAOYSA-N 0.000 claims abstract description 6
235000015218 chewing gum Nutrition 0.000 claims abstract description 6
239000000551 dentifrice Substances 0.000 claims abstract description 5
150000002910 rare earth metals Chemical class 0.000 claims abstract description 5
239000011135 tin Substances 0.000 claims abstract description 5
ATJFFYVFTNAWJD-UHFFFAOYSA-N Tin Chemical compound [Sn] ATJFFYVFTNAWJD-UHFFFAOYSA-N 0.000 claims abstract description 4
229910052782 aluminium Inorganic materials 0.000 claims abstract description 4
239000004411 aluminium Substances 0.000 claims abstract description 4
XAGFODPZIPBFFR-UHFFFAOYSA-N aluminium Chemical compound [Al] XAGFODPZIPBFFR-UHFFFAOYSA-N 0.000 claims abstract description 4
229910052718 tin Inorganic materials 0.000 claims abstract description 4
RTAQQCXQSZGOHL-UHFFFAOYSA-N Titanium Chemical compound [Ti] RTAQQCXQSZGOHL-UHFFFAOYSA-N 0.000 claims abstract description 3
HCHKCACWOHOZIP-UHFFFAOYSA-N Zinc Chemical compound [Zn] HCHKCACWOHOZIP-UHFFFAOYSA-N 0.000 claims abstract description 3
QCWXUUIWCKQGHC-UHFFFAOYSA-N Zirconium Chemical compound [Zr] QCWXUUIWCKQGHC-UHFFFAOYSA-N 0.000 claims abstract description 3
229910052742 iron Inorganic materials 0.000 claims abstract description 3
WPBNNNQJVZRUHP-UHFFFAOYSA-L manganese(2+);methyl n-[[2-(methoxycarbonylcarbamothioylamino)phenyl]carbamothioyl]carbamate;n-[2-(sulfidocarbothioylamino)ethyl]carbamodithioate Chemical compound [Mn+2].[S-]C(=S)NCCNC([S-])=S.COC(=O)NC(=S)NC1=CC=CC=C1NC(=S)NC(=O)OC WPBNNNQJVZRUHP-UHFFFAOYSA-L 0.000 claims abstract description 3
229910052719 titanium Inorganic materials 0.000 claims abstract description 3
239000010936 titanium Substances 0.000 claims abstract description 3
229910052720 vanadium Inorganic materials 0.000 claims abstract description 3
229910052725 zinc Inorganic materials 0.000 claims abstract description 3
239000011701 zinc Substances 0.000 claims abstract description 3
229910052726 zirconium Inorganic materials 0.000 claims abstract description 3
LEONUFNNVUYDNQ-UHFFFAOYSA-N vanadium atom Chemical compound [V] LEONUFNNVUYDNQ-UHFFFAOYSA-N 0.000 claims abstract 2
239000003906 humectant Substances 0.000 claims description 9
239000004094 surface-active agent Substances 0.000 claims description 7
LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 6
229940051866 mouthwash Drugs 0.000 claims description 5
229940112822 chewing gum Drugs 0.000 claims description 4
150000005846 sugar alcohols Polymers 0.000 claims description 3
229960005069 calcium Drugs 0.000 abstract description 16
239000000606 toothpaste Substances 0.000 abstract description 8
NBIIXXVUZAFLBC-UHFFFAOYSA-N Phosphoric acid Chemical compound OP(O)(O)=O NBIIXXVUZAFLBC-UHFFFAOYSA-N 0.000 abstract description 6
UXVMQQNJUSDDNG-UHFFFAOYSA-L Calcium chloride Chemical compound [Cl-].[Cl-].[Ca+2] UXVMQQNJUSDDNG-UHFFFAOYSA-L 0.000 abstract description 5
239000001110 calcium chloride Substances 0.000 abstract description 5
229910001628 calcium chloride Inorganic materials 0.000 abstract description 5
235000011148 calcium chloride Nutrition 0.000 abstract description 5
229910052746 lanthanum Inorganic materials 0.000 abstract description 5
FZLIPJUXYLNCLC-UHFFFAOYSA-N lanthanum atom Chemical compound [La] FZLIPJUXYLNCLC-UHFFFAOYSA-N 0.000 abstract description 5
229910000147 aluminium phosphate Inorganic materials 0.000 abstract description 4
BNIILDVGGAEEIG-UHFFFAOYSA-L disodium hydrogen phosphate Chemical compound [Na+].[Na+].OP([O-])([O-])=O BNIILDVGGAEEIG-UHFFFAOYSA-L 0.000 abstract description 4
229910052684 Cerium Inorganic materials 0.000 abstract description 3
239000006072 paste Substances 0.000 abstract description 3
QTBSBXVTEAMEQO-UHFFFAOYSA-M Acetate Chemical compound CC([O-])=O QTBSBXVTEAMEQO-UHFFFAOYSA-M 0.000 abstract description 2
229910002651 NO3 Inorganic materials 0.000 abstract description 2
NHNBFGGVMKEFGY-UHFFFAOYSA-N Nitrate Chemical compound [O-][N+]([O-])=O NHNBFGGVMKEFGY-UHFFFAOYSA-N 0.000 abstract description 2
239000001639 calcium acetate Substances 0.000 abstract description 2
235000011092 calcium acetate Nutrition 0.000 abstract description 2
229960005147 calcium acetate Drugs 0.000 abstract description 2
229960002713 calcium chloride Drugs 0.000 abstract description 2
239000004281 calcium formate Substances 0.000 abstract description 2
235000019255 calcium formate Nutrition 0.000 abstract description 2
229940044172 calcium formate Drugs 0.000 abstract description 2
239000001527 calcium lactate Substances 0.000 abstract description 2
235000011086 calcium lactate Nutrition 0.000 abstract description 2
229960002401 calcium lactate Drugs 0.000 abstract description 2
229910000402 monopotassium phosphate Inorganic materials 0.000 abstract description 2
235000019796 monopotassium phosphate Nutrition 0.000 abstract description 2
229910000403 monosodium phosphate Inorganic materials 0.000 abstract description 2
235000019799 monosodium phosphate Nutrition 0.000 abstract description 2
PJNZPQUBCPKICU-UHFFFAOYSA-N phosphoric acid;potassium Chemical compound [K].OP(O)(O)=O PJNZPQUBCPKICU-UHFFFAOYSA-N 0.000 abstract description 2
238000011321 prophylaxis Methods 0.000 abstract description 2
AJPJDKMHJJGVTQ-UHFFFAOYSA-M sodium dihydrogen phosphate Chemical compound [Na+].OP(O)([O-])=O AJPJDKMHJJGVTQ-UHFFFAOYSA-M 0.000 abstract description 2
239000001488 sodium phosphate Substances 0.000 abstract description 2
RYFMWSXOAZQYPI-UHFFFAOYSA-K trisodium phosphate Chemical compound [Na+].[Na+].[Na+].[O-]P([O-])([O-])=O RYFMWSXOAZQYPI-UHFFFAOYSA-K 0.000 abstract description 2
229910000406 trisodium phosphate Inorganic materials 0.000 abstract description 2
235000019801 trisodium phosphate Nutrition 0.000 abstract description 2
BDAGIHXWWSANSR-UHFFFAOYSA-M Formate Chemical compound [O-]C=O BDAGIHXWWSANSR-UHFFFAOYSA-M 0.000 abstract 1
JVTAAEKCZFNVCJ-UHFFFAOYSA-M Lactate Chemical compound CC(O)C([O-])=O JVTAAEKCZFNVCJ-UHFFFAOYSA-M 0.000 abstract 1
GWXLDORMOJMVQZ-UHFFFAOYSA-N cerium Chemical compound [Ce] GWXLDORMOJMVQZ-UHFFFAOYSA-N 0.000 abstract 1
-1 calcium cations Chemical class 0.000 description 21
239000001506 calcium phosphate Substances 0.000 description 13
QORWJWZARLRLPR-UHFFFAOYSA-H tricalcium bis(phosphate) Chemical compound [Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O QORWJWZARLRLPR-UHFFFAOYSA-H 0.000 description 13
PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 description 12
VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 description 12
239000000243 solution Substances 0.000 description 12
235000011010 calcium phosphates Nutrition 0.000 description 11
DNIAPMSPPWPWGF-UHFFFAOYSA-N Propylene glycol Chemical compound CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 description 9
239000002253 acid Substances 0.000 description 9
KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Chemical compound OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 description 9
150000002500 ions Chemical class 0.000 description 9
125000004432 carbon atom Chemical group C* 0.000 description 8
235000021317 phosphate Nutrition 0.000 description 8
229910000389 calcium phosphate Inorganic materials 0.000 description 7
239000000796 flavoring agent Substances 0.000 description 7
238000005115 demineralization Methods 0.000 description 6
230000002328 demineralizing effect Effects 0.000 description 6
235000011187 glycerol Nutrition 0.000 description 6
PUZPDOWCWNUUKD-UHFFFAOYSA-M sodium fluoride Chemical compound [F-].[Na+] PUZPDOWCWNUUKD-UHFFFAOYSA-M 0.000 description 6
DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 description 5
PSCMQHVBLHHWTO-UHFFFAOYSA-K indium(iii) chloride Chemical compound Cl[In](Cl)Cl PSCMQHVBLHHWTO-UHFFFAOYSA-K 0.000 description 5
239000011734 sodium Substances 0.000 description 5
229910052708 sodium Inorganic materials 0.000 description 5
229940034610 toothpaste Drugs 0.000 description 5
IANQTJSKSUMEQM-UHFFFAOYSA-N 1-benzofuran Chemical compound C1=CC=C2OC=CC2=C1 IANQTJSKSUMEQM-UHFFFAOYSA-N 0.000 description 4
VTYYLEPIZMXCLO-UHFFFAOYSA-L Calcium carbonate Chemical compound [Ca+2].[O-]C([O-])=O VTYYLEPIZMXCLO-UHFFFAOYSA-L 0.000 description 4
BHPQYMZQTOCNFJ-UHFFFAOYSA-N Calcium cation Chemical compound [Ca+2] BHPQYMZQTOCNFJ-UHFFFAOYSA-N 0.000 description 4
229920003171 Poly (ethylene oxide) Polymers 0.000 description 4
NCHJGQKLPRTMAO-XWVZOOPGSA-N [(2R)-2-[(2R,3R,4S)-3,4-dihydroxyoxolan-2-yl]-2-hydroxyethyl] 16-methylheptadecanoate Chemical compound CC(C)CCCCCCCCCCCCCCC(=O)OC[C@@H](O)[C@H]1OC[C@H](O)[C@H]1O NCHJGQKLPRTMAO-XWVZOOPGSA-N 0.000 description 4
239000003082 abrasive agent Substances 0.000 description 4
229910001424 calcium ion Inorganic materials 0.000 description 4
208000002925 dental caries Diseases 0.000 description 4
235000014113 dietary fatty acids Nutrition 0.000 description 4
239000000194 fatty acid Substances 0.000 description 4
229930195729 fatty acid Natural products 0.000 description 4
235000013355 food flavoring agent Nutrition 0.000 description 4
HQKMJHAJHXVSDF-UHFFFAOYSA-L magnesium stearate Chemical compound [Mg+2].CCCCCCCCCCCCCCCCCC([O-])=O.CCCCCCCCCCCCCCCCCC([O-])=O HQKMJHAJHXVSDF-UHFFFAOYSA-L 0.000 description 4
239000003921 oil Substances 0.000 description 4
210000003296 saliva Anatomy 0.000 description 4
239000000377 silicon dioxide Substances 0.000 description 4
PNEYBMLMFCGWSK-UHFFFAOYSA-N Alumina Chemical compound [O-2].[O-2].[O-2].[Al+3].[Al+3] PNEYBMLMFCGWSK-UHFFFAOYSA-N 0.000 description 3
FBPFZTCFMRRESA-FSIIMWSLSA-N D-Glucitol Natural products OC[C@H](O)[C@H](O)[C@@H](O)[C@H](O)CO FBPFZTCFMRRESA-FSIIMWSLSA-N 0.000 description 3
FBPFZTCFMRRESA-JGWLITMVSA-N D-glucitol Chemical compound OC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-JGWLITMVSA-N 0.000 description 3
OFOBLEOULBTSOW-UHFFFAOYSA-N Propanedioic acid Natural products OC(=O)CC(O)=O OFOBLEOULBTSOW-UHFFFAOYSA-N 0.000 description 3
ILRRQNADMUWWFW-UHFFFAOYSA-K aluminium phosphate Chemical compound O1[Al]2OP1(=O)O2 ILRRQNADMUWWFW-UHFFFAOYSA-K 0.000 description 3
CJZGTCYPCWQAJB-UHFFFAOYSA-L calcium stearate Chemical compound [Ca+2].CCCCCCCCCCCCCCCCCC([O-])=O.CCCCCCCCCCCCCCCCCC([O-])=O CJZGTCYPCWQAJB-UHFFFAOYSA-L 0.000 description 3
235000015165 citric acid Nutrition 0.000 description 3
229910000397 disodium phosphate Inorganic materials 0.000 description 3
235000019634 flavors Nutrition 0.000 description 3
235000003599 food sweetener Nutrition 0.000 description 3
239000000463 material Substances 0.000 description 3
238000000034 method Methods 0.000 description 3
229920001223 polyethylene glycol Polymers 0.000 description 3
230000001376 precipitating effect Effects 0.000 description 3
229920005989 resin Polymers 0.000 description 3
239000011347 resin Substances 0.000 description 3
CVHZOJJKTDOEJC-UHFFFAOYSA-N saccharin Chemical compound C1=CC=C2C(=O)NS(=O)(=O)C2=C1 CVHZOJJKTDOEJC-UHFFFAOYSA-N 0.000 description 3
229940081974 saccharin Drugs 0.000 description 3
235000019204 saccharin Nutrition 0.000 description 3
239000000901 saccharin and its Na,K and Ca salt Substances 0.000 description 3
239000011775 sodium fluoride Substances 0.000 description 3
235000013024 sodium fluoride Nutrition 0.000 description 3
239000000600 sorbitol Substances 0.000 description 3
239000000375 suspending agent Substances 0.000 description 3
239000003765 sweetening agent Substances 0.000 description 3
XOAAWQZATWQOTB-UHFFFAOYSA-N taurine Chemical compound NCCS(O)(=O)=O XOAAWQZATWQOTB-UHFFFAOYSA-N 0.000 description 3
239000002562 thickening agent Substances 0.000 description 3
PBYZMCDFOULPGH-UHFFFAOYSA-N tungstate Chemical compound [O-][W]([O-])(=O)=O PBYZMCDFOULPGH-UHFFFAOYSA-N 0.000 description 3
ALYNCZNDIQEVRV-UHFFFAOYSA-N 4-aminobenzoic acid Chemical compound NC1=CC=C(C(O)=O)C=C1 ALYNCZNDIQEVRV-UHFFFAOYSA-N 0.000 description 2
ZEYHEAKUIGZSGI-UHFFFAOYSA-N 4-methoxybenzoic acid Chemical compound COC1=CC=C(C(O)=O)C=C1 ZEYHEAKUIGZSGI-UHFFFAOYSA-N 0.000 description 2
QTBSBXVTEAMEQO-UHFFFAOYSA-N Acetic acid Chemical compound CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 description 2
229910002012 Aerosil® Inorganic materials 0.000 description 2
CIWBSHSKHKDKBQ-JLAZNSOCSA-N Ascorbic acid Chemical compound OC[C@H](O)[C@H]1OC(=O)C(O)=C1O CIWBSHSKHKDKBQ-JLAZNSOCSA-N 0.000 description 2
BVKZGUZCCUSVTD-UHFFFAOYSA-L Carbonate Chemical compound [O-]C([O-])=O BVKZGUZCCUSVTD-UHFFFAOYSA-L 0.000 description 2
FEWJPZIEWOKRBE-JCYAYHJZSA-N Dextrotartaric acid Chemical compound OC(=O)[C@H](O)[C@@H](O)C(O)=O FEWJPZIEWOKRBE-JCYAYHJZSA-N 0.000 description 2
VZCYOOQTPOCHFL-OWOJBTEDSA-N Fumaric acid Chemical compound OC(=O)\C=C\C(O)=O VZCYOOQTPOCHFL-OWOJBTEDSA-N 0.000 description 2
DHMQDGOQFOQNFH-UHFFFAOYSA-N Glycine Chemical compound NCC(O)=O DHMQDGOQFOQNFH-UHFFFAOYSA-N 0.000 description 2
AEMRFAOFKBGASW-UHFFFAOYSA-N Glycolic acid Chemical compound OCC(O)=O AEMRFAOFKBGASW-UHFFFAOYSA-N 0.000 description 2
239000004354 Hydroxyethyl cellulose Substances 0.000 description 2
229920000663 Hydroxyethyl cellulose Polymers 0.000 description 2
239000005662 Paraffin oil Substances 0.000 description 2
239000002202 Polyethylene glycol Substances 0.000 description 2
239000004965 Silica aerogel Substances 0.000 description 2
DBMJMQXJHONAFJ-UHFFFAOYSA-M Sodium laurylsulphate Chemical compound [Na+].CCCCCCCCCCCCOS([O-])(=O)=O DBMJMQXJHONAFJ-UHFFFAOYSA-M 0.000 description 2
QAOWNCQODCNURD-UHFFFAOYSA-L Sulfate Chemical compound [O-]S([O-])(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-L 0.000 description 2
150000008051 alkyl sulfates Chemical class 0.000 description 2
POJWUDADGALRAB-UHFFFAOYSA-N allantoin Chemical compound NC(=O)NC1NC(=O)NC1=O POJWUDADGALRAB-UHFFFAOYSA-N 0.000 description 2
WPYMKLBDIGXBTP-UHFFFAOYSA-N benzoic acid Chemical compound OC(=O)C1=CC=CC=C1 WPYMKLBDIGXBTP-UHFFFAOYSA-N 0.000 description 2
229910000019 calcium carbonate Inorganic materials 0.000 description 2
JUNWLZAGQLJVLR-UHFFFAOYSA-J calcium diphosphate Chemical compound [Ca+2].[Ca+2].[O-]P([O-])(=O)OP([O-])([O-])=O JUNWLZAGQLJVLR-UHFFFAOYSA-J 0.000 description 2
ZCCIPPOKBCJFDN-UHFFFAOYSA-N calcium nitrate Chemical compound [Ca+2].[O-][N+]([O-])=O.[O-][N+]([O-])=O ZCCIPPOKBCJFDN-UHFFFAOYSA-N 0.000 description 2
229940043256 calcium pyrophosphate Drugs 0.000 description 2
239000008116 calcium stearate Substances 0.000 description 2
235000013539 calcium stearate Nutrition 0.000 description 2
239000001768 carboxy methyl cellulose Substances 0.000 description 2
ZMIGMASIKSOYAM-UHFFFAOYSA-N cerium Chemical compound [Ce][Ce][Ce][Ce][Ce][Ce][Ce][Ce][Ce][Ce][Ce][Ce][Ce][Ce][Ce][Ce][Ce][Ce][Ce][Ce][Ce][Ce][Ce][Ce][Ce][Ce][Ce][Ce][Ce][Ce][Ce][Ce][Ce][Ce][Ce][Ce][Ce][Ce] ZMIGMASIKSOYAM-UHFFFAOYSA-N 0.000 description 2
239000003795 chemical substances by application Substances 0.000 description 2
235000019821 dicalcium diphosphate Nutrition 0.000 description 2
RBLGLDWTCZMLRW-UHFFFAOYSA-K dicalcium;phosphate;dihydrate Chemical compound O.O.[Ca+2].[Ca+2].[O-]P([O-])([O-])=O RBLGLDWTCZMLRW-UHFFFAOYSA-K 0.000 description 2
238000009792 diffusion process Methods 0.000 description 2
XBDQKXXYIPTUBI-UHFFFAOYSA-N dimethylselenoniopropionate Natural products CCC(O)=O XBDQKXXYIPTUBI-UHFFFAOYSA-N 0.000 description 2
235000019800 disodium phosphate Nutrition 0.000 description 2
POULHZVOKOAJMA-UHFFFAOYSA-M dodecanoate Chemical compound CCCCCCCCCCCC([O-])=O POULHZVOKOAJMA-UHFFFAOYSA-M 0.000 description 2
229910021485 fumed silica Inorganic materials 0.000 description 2
235000010985 glycerol esters of wood rosin Nutrition 0.000 description 2
KWIUHFFTVRNATP-UHFFFAOYSA-N glycine betaine Chemical compound C[N+](C)(C)CC([O-])=O KWIUHFFTVRNATP-UHFFFAOYSA-N 0.000 description 2
235000019447 hydroxyethyl cellulose Nutrition 0.000 description 2
238000010348 incorporation Methods 0.000 description 2
UJXZVRRCKFUQKG-UHFFFAOYSA-K indium(3+);phosphate Chemical compound [In+3].[O-]P([O-])([O-])=O UJXZVRRCKFUQKG-UHFFFAOYSA-K 0.000 description 2
MRELNEQAGSRDBK-UHFFFAOYSA-N lanthanum(3+);oxygen(2-) Chemical compound [O-2].[O-2].[O-2].[La+3].[La+3] MRELNEQAGSRDBK-UHFFFAOYSA-N 0.000 description 2
229940070765 laurate Drugs 0.000 description 2
235000019359 magnesium stearate Nutrition 0.000 description 2
229910052751 metal Inorganic materials 0.000 description 2
239000002184 metal Substances 0.000 description 2
BDAGIHXWWSANSR-UHFFFAOYSA-N methanoic acid Natural products OC=O BDAGIHXWWSANSR-UHFFFAOYSA-N 0.000 description 2
239000002480 mineral oil Substances 0.000 description 2
235000010446 mineral oil Nutrition 0.000 description 2
QIQXTHQIDYTFRH-UHFFFAOYSA-N octadecanoic acid Chemical compound CCCCCCCCCCCCCCCCCC(O)=O QIQXTHQIDYTFRH-UHFFFAOYSA-N 0.000 description 2
KHPXUQMNIQBQEV-UHFFFAOYSA-N oxaloacetic acid Chemical compound OC(=O)CC(=O)C(O)=O KHPXUQMNIQBQEV-UHFFFAOYSA-N 0.000 description 2
239000012188 paraffin wax Substances 0.000 description 2
239000002245 particle Substances 0.000 description 2
WLJVNTCWHIRURA-UHFFFAOYSA-N pimelic acid Chemical compound OC(=O)CCCCCC(O)=O WLJVNTCWHIRURA-UHFFFAOYSA-N 0.000 description 2
NROKBHXJSPEDAR-UHFFFAOYSA-M potassium fluoride Chemical compound [F-].[K+] NROKBHXJSPEDAR-UHFFFAOYSA-M 0.000 description 2
238000002360 preparation method Methods 0.000 description 2
239000000047 product Substances 0.000 description 2
235000019333 sodium laurylsulphate Nutrition 0.000 description 2
239000007787 solid Substances 0.000 description 2
229940104261 taurate Drugs 0.000 description 2
XOLBLPGZBRYERU-UHFFFAOYSA-N tin dioxide Chemical compound O=[Sn]=O XOLBLPGZBRYERU-UHFFFAOYSA-N 0.000 description 2
VZCYOOQTPOCHFL-UHFFFAOYSA-N trans-butenedioic acid Natural products OC(=O)C=CC(O)=O VZCYOOQTPOCHFL-UHFFFAOYSA-N 0.000 description 2
QAIPRVGONGVQAS-DUXPYHPUSA-N trans-caffeic acid Chemical compound OC(=O)\C=C\C1=CC=C(O)C(O)=C1 QAIPRVGONGVQAS-DUXPYHPUSA-N 0.000 description 2
NQPDZGIKBAWPEJ-UHFFFAOYSA-N valeric acid Chemical compound CCCCC(O)=O NQPDZGIKBAWPEJ-UHFFFAOYSA-N 0.000 description 2
229920001285 xanthan gum Polymers 0.000 description 2
239000000230 xanthan gum Substances 0.000 description 2
235000010493 xanthan gum Nutrition 0.000 description 2
229940082509 xanthan gum Drugs 0.000 description 2
LRXTYHSAJDENHV-UHFFFAOYSA-H zinc phosphate Chemical compound [Zn+2].[Zn+2].[Zn+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O LRXTYHSAJDENHV-UHFFFAOYSA-H 0.000 description 2
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ZQALOCIMMBGHGK-UHFFFAOYSA-L magnesium;hexadecane-1-sulfonate Chemical compound [Mg+2].CCCCCCCCCCCCCCCCS([O-])(=O)=O.CCCCCCCCCCCCCCCCS([O-])(=O)=O ZQALOCIMMBGHGK-UHFFFAOYSA-L 0.000 description 1
ABSWXCXMXIZDSN-UHFFFAOYSA-L magnesium;hexadecanoate Chemical compound [Mg+2].CCCCCCCCCCCCCCCC([O-])=O.CCCCCCCCCCCCCCCC([O-])=O ABSWXCXMXIZDSN-UHFFFAOYSA-L 0.000 description 1
WWCDIIHUGYGFOU-UHFFFAOYSA-L magnesium;octadecane-1-sulfonate Chemical compound [Mg+2].CCCCCCCCCCCCCCCCCCS([O-])(=O)=O.CCCCCCCCCCCCCCCCCCS([O-])(=O)=O WWCDIIHUGYGFOU-UHFFFAOYSA-L 0.000 description 1
HXHSBMHLZQUAFK-UHFFFAOYSA-L magnesium;tetradecane-1-sulfonate Chemical compound [Mg+2].CCCCCCCCCCCCCCS([O-])(=O)=O.CCCCCCCCCCCCCCS([O-])(=O)=O HXHSBMHLZQUAFK-UHFFFAOYSA-L 0.000 description 1
DMRBHZWQMKSQGR-UHFFFAOYSA-L magnesium;tetradecanoate Chemical compound [Mg+2].CCCCCCCCCCCCCC([O-])=O.CCCCCCCCCCCCCC([O-])=O DMRBHZWQMKSQGR-UHFFFAOYSA-L 0.000 description 1
VZCYOOQTPOCHFL-UPHRSURJSA-N maleic acid Chemical compound OC(=O)\C=C/C(O)=O VZCYOOQTPOCHFL-UPHRSURJSA-N 0.000 description 1
239000011976 maleic acid Substances 0.000 description 1
239000001630 malic acid Substances 0.000 description 1
235000011090 malic acid Nutrition 0.000 description 1
239000011656 manganese carbonate Substances 0.000 description 1
235000006748 manganese carbonate Nutrition 0.000 description 1
229940093474 manganese carbonate Drugs 0.000 description 1
IPJKJLXEVHOKSE-UHFFFAOYSA-L manganese dihydroxide Chemical compound [OH-].[OH-].[Mn+2] IPJKJLXEVHOKSE-UHFFFAOYSA-L 0.000 description 1
229910000016 manganese(II) carbonate Inorganic materials 0.000 description 1
XMWCXZJXESXBBY-UHFFFAOYSA-L manganese(ii) carbonate Chemical compound [Mn+2].[O-]C([O-])=O XMWCXZJXESXBBY-UHFFFAOYSA-L 0.000 description 1
HNEGQIOMVPPMNR-NSCUHMNNSA-N mesaconic acid Chemical compound OC(=O)C(/C)=C/C(O)=O HNEGQIOMVPPMNR-NSCUHMNNSA-N 0.000 description 1
150000002739 metals Chemical class 0.000 description 1
125000005341 metaphosphate group Chemical group 0.000 description 1
AXLHVTKGDPVANO-UHFFFAOYSA-N methyl 2-amino-3-[(2-methylpropan-2-yl)oxycarbonylamino]propanoate Chemical compound COC(=O)C(N)CNC(=O)OC(C)(C)C AXLHVTKGDPVANO-UHFFFAOYSA-N 0.000 description 1
229920000609 methyl cellulose Polymers 0.000 description 1
YLGXILFCIXHCMC-JHGZEJCSSA-N methyl cellulose Chemical compound COC1C(OC)C(OC)C(COC)O[C@H]1O[C@H]1C(OC)C(OC)C(OC)OC1COC YLGXILFCIXHCMC-JHGZEJCSSA-N 0.000 description 1
WBYWAXJHAXSJNI-UHFFFAOYSA-N methyl p-hydroxycinnamate Natural products OC(=O)C=CC1=CC=CC=C1 WBYWAXJHAXSJNI-UHFFFAOYSA-N 0.000 description 1
OSWPMRLSEDHDFF-UHFFFAOYSA-N methyl salicylate Chemical compound COC(=O)C1=CC=CC=C1O OSWPMRLSEDHDFF-UHFFFAOYSA-N 0.000 description 1
235000010981 methylcellulose Nutrition 0.000 description 1
239000001923 methylcellulose Substances 0.000 description 1
LVHBHZANLOWSRM-UHFFFAOYSA-N methylenebutanedioic acid Natural products OC(=O)CC(=C)C(O)=O LVHBHZANLOWSRM-UHFFFAOYSA-N 0.000 description 1
HNEGQIOMVPPMNR-UHFFFAOYSA-N methylfumaric acid Natural products OC(=O)C(C)=CC(O)=O HNEGQIOMVPPMNR-UHFFFAOYSA-N 0.000 description 1
230000005012 migration Effects 0.000 description 1
238000013508 migration Methods 0.000 description 1
238000002156 mixing Methods 0.000 description 1
MEFBJEMVZONFCJ-UHFFFAOYSA-N molybdate Chemical compound [O-][Mo]([O-])(=O)=O MEFBJEMVZONFCJ-UHFFFAOYSA-N 0.000 description 1
239000001788 mono and diglycerides of fatty acids Substances 0.000 description 1
235000019960 monoglycerides of fatty acid Nutrition 0.000 description 1
229940105132 myristate Drugs 0.000 description 1
229920003052 natural elastomer Polymers 0.000 description 1
229920001206 natural gum Polymers 0.000 description 1
229920001194 natural rubber Polymers 0.000 description 1
QEFYFXOXNSNQGX-UHFFFAOYSA-N neodymium atom Chemical compound [Nd] QEFYFXOXNSNQGX-UHFFFAOYSA-N 0.000 description 1
BFDHFSHZJLFAMC-UHFFFAOYSA-L nickel(ii) hydroxide Chemical compound [OH-].[OH-].[Ni+2] BFDHFSHZJLFAMC-UHFFFAOYSA-L 0.000 description 1
239000013588 oral product Substances 0.000 description 1
XYJRXVWERLGGKC-UHFFFAOYSA-D pentacalcium;hydroxide;triphosphate Chemical compound [OH-].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O XYJRXVWERLGGKC-UHFFFAOYSA-D 0.000 description 1
229940085991 phosphate ion Drugs 0.000 description 1
239000000049 pigment Substances 0.000 description 1
239000004033 plastic Substances 0.000 description 1
229920003023 plastic Polymers 0.000 description 1
229920001282 polysaccharide Polymers 0.000 description 1
239000005017 polysaccharide Substances 0.000 description 1
229920002689 polyvinyl acetate Polymers 0.000 description 1
239000011118 polyvinyl acetate Substances 0.000 description 1
239000011591 potassium Substances 0.000 description 1
229910052700 potassium Inorganic materials 0.000 description 1
239000011698 potassium fluoride Substances 0.000 description 1
235000003270 potassium fluoride Nutrition 0.000 description 1
238000001556 precipitation Methods 0.000 description 1
235000019260 propionic acid Nutrition 0.000 description 1
IUVKMZGDUIUOCP-BTNSXGMBSA-N quinbolone Chemical compound O([C@H]1CC[C@H]2[C@H]3[C@@H]([C@]4(C=CC(=O)C=C4CC3)C)CC[C@@]21C)C1=CCCC1 IUVKMZGDUIUOCP-BTNSXGMBSA-N 0.000 description 1
230000000717 retained effect Effects 0.000 description 1
230000000979 retarding effect Effects 0.000 description 1
230000000630 rising effect Effects 0.000 description 1
BJRVEOKYZKROCC-UHFFFAOYSA-K samarium(3+);phosphate Chemical compound [Sm+3].[O-]P([O-])([O-])=O BJRVEOKYZKROCC-UHFFFAOYSA-K 0.000 description 1
OJIKOZJGHCVMDC-UHFFFAOYSA-K samarium(iii) fluoride Chemical class F[Sm](F)F OJIKOZJGHCVMDC-UHFFFAOYSA-K 0.000 description 1
229920006395 saturated elastomer Polymers 0.000 description 1
QYHFIVBSNOWOCQ-UHFFFAOYSA-N selenic acid Chemical compound O[Se](O)(=O)=O QYHFIVBSNOWOCQ-UHFFFAOYSA-N 0.000 description 1
MCAHWIHFGHIESP-UHFFFAOYSA-N selenous acid Chemical compound O[Se](O)=O MCAHWIHFGHIESP-UHFFFAOYSA-N 0.000 description 1
229910002028 silica xerogel Inorganic materials 0.000 description 1
239000000344 soap Substances 0.000 description 1
235000019812 sodium carboxymethyl cellulose Nutrition 0.000 description 1
229920001027 sodium carboxymethylcellulose Polymers 0.000 description 1
AQMNWCRSESPIJM-UHFFFAOYSA-M sodium metaphosphate Chemical compound [Na+].[O-]P(=O)=O AQMNWCRSESPIJM-UHFFFAOYSA-M 0.000 description 1
229940075554 sorbate Drugs 0.000 description 1
229940035044 sorbitan monolaurate Drugs 0.000 description 1
ANOBYBYXJXCGBS-UHFFFAOYSA-L stannous fluoride Chemical compound F[Sn]F ANOBYBYXJXCGBS-UHFFFAOYSA-L 0.000 description 1
229960002799 stannous fluoride Drugs 0.000 description 1
229910052567 struvite Inorganic materials 0.000 description 1
BDHFUVZGWQCTTF-UHFFFAOYSA-M sulfonate Chemical compound [O-]S(=O)=O BDHFUVZGWQCTTF-UHFFFAOYSA-M 0.000 description 1
239000000725 suspension Substances 0.000 description 1
239000000271 synthetic detergent Substances 0.000 description 1
239000011975 tartaric acid Substances 0.000 description 1
235000002906 tartaric acid Nutrition 0.000 description 1
229940095064 tartrate Drugs 0.000 description 1
229960003080 taurine Drugs 0.000 description 1
TUNFSRHWOTWDNC-UHFFFAOYSA-N tetradecanoic acid Chemical compound CCCCCCCCCCCCCC(O)=O TUNFSRHWOTWDNC-UHFFFAOYSA-N 0.000 description 1
229920001187 thermosetting polymer Polymers 0.000 description 1
QUBMWJKTLKIJNN-UHFFFAOYSA-B tin(4+);tetraphosphate Chemical compound [Sn+4].[Sn+4].[Sn+4].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O QUBMWJKTLKIJNN-UHFFFAOYSA-B 0.000 description 1
229910052723 transition metal Inorganic materials 0.000 description 1
150000003624 transition metals Chemical class 0.000 description 1
238000011282 treatment Methods 0.000 description 1
229940078499 tricalcium phosphate Drugs 0.000 description 1
229910000391 tricalcium phosphate Inorganic materials 0.000 description 1
235000019731 tricalcium phosphate Nutrition 0.000 description 1
JOPDZQBPOWAEHC-UHFFFAOYSA-H tristrontium;diphosphate Chemical compound [Sr+2].[Sr+2].[Sr+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O JOPDZQBPOWAEHC-UHFFFAOYSA-H 0.000 description 1
229940005605 valeric acid Drugs 0.000 description 1
GPPXJZIENCGNKB-UHFFFAOYSA-N vanadium Chemical compound [V]#[V] GPPXJZIENCGNKB-UHFFFAOYSA-N 0.000 description 1
239000009637 wintergreen oil Substances 0.000 description 1
229910009112 xH2O Inorganic materials 0.000 description 1
239000011667 zinc carbonate Substances 0.000 description 1
235000004416 zinc carbonate Nutrition 0.000 description 1
229910000010 zinc carbonate Inorganic materials 0.000 description 1
UGZADUVQMDAIAO-UHFFFAOYSA-L zinc hydroxide Chemical compound [OH-].[OH-].[Zn+2] UGZADUVQMDAIAO-UHFFFAOYSA-L 0.000 description 1
229910021511 zinc hydroxide Inorganic materials 0.000 description 1
229940007718 zinc hydroxide Drugs 0.000 description 1
229910000165 zinc phosphate Inorganic materials 0.000 description 1
XOOUIPVCVHRTMJ-UHFFFAOYSA-L zinc stearate Chemical compound [Zn+2].CCCCCCCCCCCCCCCCCC([O-])=O.CCCCCCCCCCCCCCCCCC([O-])=O XOOUIPVCVHRTMJ-UHFFFAOYSA-L 0.000 description 1
VRGNUPCISFMPEM-ZVGUSBNCSA-L zinc;(2r,3r)-2,3-dihydroxybutanedioate Chemical compound [Zn+2].[O-]C(=O)[C@H](O)[C@@H](O)C([O-])=O VRGNUPCISFMPEM-ZVGUSBNCSA-L 0.000 description 1
ZPEJZWGMHAKWNL-UHFFFAOYSA-L zinc;oxalate Chemical compound [Zn+2].[O-]C(=O)C([O-])=O ZPEJZWGMHAKWNL-UHFFFAOYSA-L 0.000 description 1
229910000166 zirconium phosphate Inorganic materials 0.000 description 1
LEHFSLREWWMLPU-UHFFFAOYSA-B zirconium(4+);tetraphosphate Chemical compound [Zr+4].[Zr+4].[Zr+4].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O LEHFSLREWWMLPU-UHFFFAOYSA-B 0.000 description 1
GFQYVLUOOAAOGM-UHFFFAOYSA-N zirconium(iv) silicate Chemical compound [Zr+4].[O-][Si]([O-])([O-])[O-] GFQYVLUOOAAOGM-UHFFFAOYSA-N 0.000 description 1

Classifications

- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23G—COCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF
- A23G4/00—Chewing gum
- A23G4/06—Chewing gum characterised by the composition containing organic or inorganic compounds
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23G—COCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF
- A23G4/00—Chewing gum
- A23G4/06—Chewing gum characterised by the composition containing organic or inorganic compounds
- A23G4/064—Chewing gum characterised by the composition containing organic or inorganic compounds containing inorganic compounds
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
- A61K8/24—Phosphorous; Compounds thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/80—Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
- A61K2800/88—Two- or multipart kits

Landscapes

Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Inorganic Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Food Science & Technology (AREA)
Epidemiology (AREA)
Birds (AREA)
Polymers & Plastics (AREA)
Engineering & Computer Science (AREA)
Oral & Maxillofacial Surgery (AREA)
Cosmetics (AREA)
Dental Preparations (AREA)

IE2027/75A 1974-10-10 1975-09-16 Compositions for remineralizing tooth enamel IE42129B1 (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US51362374A	1974-10-10	1974-10-10

Publications (2)

Publication Number	Publication Date
IE42129L IE42129L (en)	1976-04-10
IE42129B1 true IE42129B1 (en)	1980-06-04

Family

ID=24044015

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IE2027/75A IE42129B1 (en)	1974-10-10	1975-09-16	Compositions for remineralizing tooth enamel

Country Status (12)

Country	Link
JP (1)	JPS5191339A (it)
AT (1)	AT349641B (it)
AU (1)	AU8534175A (it)
BE (1)	BE834338A (it)
DE (1)	DE2543489A1 (it)
ES (1)	ES441715A1 (it)
FR (1)	FR2287234A1 (it)
GB (1)	GB1516525A (it)
IE (1)	IE42129B1 (it)
IT (1)	IT1043251B (it)
NL (1)	NL7511850A (it)
SE (1)	SE7511327L (it)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CA1096306A (en) *	1977-04-04	1981-02-24	Joseph C. Muhler	Anticariogenic comestible
CA1226525A (en)	1977-06-23	1987-09-08	Gunnar Rolla	Lanthanum cation for cleaning teeth
ATE28398T1 (de) *	1982-04-20	1987-08-15	Beecham Group Plc	Mittel zur mundhygiene.
US4419346A (en) *	1982-08-13	1983-12-06	Nabisco Brands, Inc.	Method and composition to inhibit the growth of Streptococcus mutans by the use of saccharin/fluoride combination
JPS6056314U (ja) *	1983-08-29	1985-04-19	セイコー株式会社	装身具
EP0206991A3 (en) *	1985-06-12	1987-04-15	Warner-Lambert Company	Monofluorophosphate containing chewing gum composition
US4828849A (en) *	1988-01-14	1989-05-09	Warner-Lambert Company	Surfactant inhibition of dental plaque
US5049375A (en) *	1989-05-31	1991-09-17	Kao Corporation	Oral compositions containing colloidal fluoride
DE4221054A1 (de) *	1992-06-30	1994-01-05	Herbst Bremer Goldschlaegerei	Präparat zur prophylaktischen und therapeutischen Behandlung von Karies sowie Verfahren zum Herstellen desselben
GB9603518D0 (en)	1996-02-20	1996-04-17	Smithkline Beecham Plc	Novel process
GB9717598D0 (en) *	1997-08-19	1997-10-22	Smithkline Beecham Plc	Novel composition and use
GB9819530D0 (en)	1998-09-09	1998-10-28	Smithkline Beecham Plc	Novel compositions and use
WO2002092027A2 (en) *	2001-05-15	2002-11-21	The Procter & Gamble Company	Confectionery compositions
DE10349050A1 (de) *	2003-10-17	2005-05-12	Nova Dentalia Zahnpflege Gmbh	Kaumasse zur Remineralisation von Zahnschmelz
JP2008507480A (ja) *	2004-07-23	2008-03-13	トムスグルッペンエー／エス	唾液中における浸食可能性のない酸性固形口腔用組成物および唾液中の浸食可能性を測定する方法
RU2380081C2 (ru) *	2008-01-09	2010-01-27	Государственное образовательное учреждение высшего профессионального образования "Уральская государственная медицинская академия Федерального агентства по здравоохранению и социальному развитию" (ГОУ ВПО УГМА Росздрава)	Состав для лечения и профилактики заболеваний полости рта
TWI404544B (zh)	2008-08-11	2013-08-11	美國棕欖公司	含珠粒之口腔保健組成物
WO2011109919A1 (en)	2010-03-09	2011-09-15	Unilever Plc	Stable oral care compositions
BR112015032853B1 (pt) *	2013-07-19	2020-12-01	Unilever Nv	produto de tratamento oral e método de remineralização de dente
JP6751027B2 (ja) *	2014-07-11	2020-09-02	コーニンクレッカフィリップスエヌヴェＫｏｎｉｎｋｌｉｊｋｅＰｈｉｌｉｐｓＮ．Ｖ．	非晶質リン酸カルシウムを供給する口腔ケア処方システム
CN107743386A (zh)	2015-06-05	2018-02-27	荷兰联合利华有限公司	口腔护理装置
JP7447470B2 (ja) *	2019-12-19	2024-03-12	ライオン株式会社	歯磨剤組成物

1975
- 1975-09-16 IE IE2027/75A patent/IE42129B1/en unknown
- 1975-09-30 DE DE2543489A patent/DE2543489A1/de not_active Withdrawn
- 1975-10-01 AU AU85341/75A patent/AU8534175A/en not_active Expired
- 1975-10-09 FR FR7530965A patent/FR2287234A1/fr active Granted
- 1975-10-09 NL NL7511850A patent/NL7511850A/xx not_active Application Discontinuation
- 1975-10-09 BE BE160801A patent/BE834338A/xx unknown
- 1975-10-09 IT IT28130/75A patent/IT1043251B/it active
- 1975-10-09 GB GB41435/75A patent/GB1516525A/en not_active Expired
- 1975-10-09 SE SE7511327A patent/SE7511327L/xx unknown
- 1975-10-09 JP JP50122389A patent/JPS5191339A/ja active Pending
- 1975-10-09 AT AT772275A patent/AT349641B/de not_active IP Right Cessation
- 1975-10-10 ES ES441715A patent/ES441715A1/es not_active Expired

Also Published As

Publication number	Publication date
FR2287234A1 (fr)	1976-05-07
BE834338A (fr)	1976-04-09
IE42129L (en)	1976-04-10
IT1043251B (it)	1980-02-20
NL7511850A (nl)	1976-04-13
JPS5191339A (en)	1976-08-10
SE7511327L (sv)	1976-04-12
FR2287234B1 (it)	1978-09-22
ES441715A1 (es)	1977-06-16
AU8534175A (en)	1977-04-07
DE2543489A1 (de)	1976-04-22
ATA772275A (de)	1978-09-15
AT349641B (de)	1979-04-10
GB1516525A (en)	1978-07-05

Publication	Publication Date	Title
US4080440A (en)	1978-03-21	Method for remineralizing tooth enamel
US4565691A (en)	1986-01-21	Oral hygiene compositions
US4183914A (en)	1980-01-15	Magnesium polycarboxylate complexes and anticalculus agents
US6036944A (en)	2000-03-14	Processes for the remineralization and mineralization of teeth
US5833957A (en)	1998-11-10	Processes and compositions for the remineralization of teeth
CA1113007A (en)	1981-11-24	Fluoride and stannous salt in acidic oral composition
US5817296A (en)	1998-10-06	Processes and compositions for the remineralization of teeth
US4847070A (en)	1989-07-11	Anticalculus compositions
US5145666A (en)	1992-09-08	Methods of reducing plaque and gingivitis with reduced staining
US3966863A (en)	1976-06-29	Oral hygiene compositions
US5213790A (en)	1993-05-25	Methods of reducing plaque and gingivitis with reduced staining
US4108979A (en)	1978-08-22	Dentifrice preparations comprising aluminum and a compatible abrasive
CA2116225C (en)	1999-06-15	Anticalculus dentifrices
US6372198B1 (en)	2002-04-16	Dentifrice for the mineralization and remineralization of teeth
US6159449A (en)	2000-12-12	Dentifrice products and methods for remineralizing and/or mineralizing teeth
GB2188548A (en)	1987-10-07	Oral hygiene compositions
US4217343A (en)	1980-08-12	Magnesium polycarboxylate complexes as anticalculus agents
NZ229360A (en)	1991-10-25	Antiplaque and antigingivitis composition containing a chlorous acid liberating compound
EP0930867A1 (en)	1999-07-28	Improved products and methods for the remineralization and prevention of demineralization of teeth
GB2216005A (en)	1989-10-04	Dental compositions containing stannous ions
DE2543489A1 (de)	1976-04-22	Mittel zum remineralisieren von zahnschmelz
US4217342A (en)	1980-08-12	Magnesium polycarboxylate complexes as anticalculus agents
IE54280B1 (en)	1989-08-16	Fluoride containing dentifrice
EP0089136A2 (en)	1983-09-21	Oral hygiene products
CA1060346A (en)	1979-08-14	Method for remineralizing tooth enamel