IE42203L - Benzenedisulfonamides. - Google Patents

Benzenedisulfonamides.

Info

Publication number
IE42203L
IE42203L IE752666A IE266675A IE42203L IE 42203 L IE42203 L IE 42203L IE 752666 A IE752666 A IE 752666A IE 266675 A IE266675 A IE 266675A IE 42203 L IE42203 L IE 42203L
Authority
IE
Ireland
Prior art keywords
benzenedisulfonamides
compounds
substituted
disclosed
active
Prior art date
Application number
IE752666A
Other versions
IE42203B1 (en
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US05/616,331 external-priority patent/US4064239A/en
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Publication of IE42203L publication Critical patent/IE42203L/en
Publication of IE42203B1 publication Critical patent/IE42203B1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
    • C07C311/30—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound nitrogen atoms, not being part of nitro or nitroso groups
    • C07C311/37—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound nitrogen atoms, not being part of nitro or nitroso groups having the sulfur atom of at least one of the sulfonamide groups bound to a carbon atom of a six-membered aromatic ring
    • C07C311/38—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound nitrogen atoms, not being part of nitro or nitroso groups having the sulfur atom of at least one of the sulfonamide groups bound to a carbon atom of a six-membered aromatic ring having sulfur atoms of sulfonamide groups and amino groups bound to carbon atoms of six-membered rings of the same carbon skeleton
    • C07C311/39—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound nitrogen atoms, not being part of nitro or nitroso groups having the sulfur atom of at least one of the sulfonamide groups bound to a carbon atom of a six-membered aromatic ring having sulfur atoms of sulfonamide groups and amino groups bound to carbon atoms of six-membered rings of the same carbon skeleton having the nitrogen atom of at least one of the sulfonamide groups bound to hydrogen atoms or to an acyclic carbon atom
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K20/00—Accessory food factors for animal feeding-stuffs
    • A23K20/10—Organic substances
    • A23K20/111—Aromatic compounds
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K20/00—Accessory food factors for animal feeding-stuffs
    • A23K20/10—Organic substances
    • A23K20/116—Heterocyclic compounds
    • A23K20/121—Heterocyclic compounds containing oxygen or sulfur as hetero atom
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K20/00—Accessory food factors for animal feeding-stuffs
    • A23K20/10—Organic substances
    • A23K20/116—Heterocyclic compounds
    • A23K20/137—Heterocyclic compounds containing two hetero atoms, of which at least one is nitrogen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/63—Compounds containing para-N-benzenesulfonyl-N-groups, e.g. sulfanilamide, p-nitrobenzenesulfonyl hydrazide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C17/00—Preparation of halogenated hydrocarbons
    • C07C17/013—Preparation of halogenated hydrocarbons by addition of halogens
    • C07C17/04—Preparation of halogenated hydrocarbons by addition of halogens to unsaturated halogenated hydrocarbons
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C17/00—Preparation of halogenated hydrocarbons
    • C07C17/26—Preparation of halogenated hydrocarbons by reactions involving an increase in the number of carbon atoms in the skeleton
    • C07C17/263—Preparation of halogenated hydrocarbons by reactions involving an increase in the number of carbon atoms in the skeleton by condensation reactions
    • C07C17/2637—Preparation of halogenated hydrocarbons by reactions involving an increase in the number of carbon atoms in the skeleton by condensation reactions between a compound containing only oxygen and possibly halogen as hetero-atoms and a halogenated hydrocarbon
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C205/00—Compounds containing nitro groups bound to a carbon skeleton
    • C07C205/07—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by halogen atoms
    • C07C205/11—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by halogen atoms having nitro groups bound to carbon atoms of six-membered aromatic rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Polymers & Plastics (AREA)
  • Animal Husbandry (AREA)
  • Food Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Novel substituted benzenedisulfonamides are disclosed which compounds are active anthelmintic agents being particularly useful against fascioliasis in sheep and cattle. Speci?ically the active compounds are 4-amino-1,3-benzenedisulfonamide compounds substituted at the 6position with an unsaturated substituted alkyl group. Compositions and methods containing the novel substituted benzenedisulfonamides for use in anthelmintic therapy particularly againt liver fluke are also disclosed. [CA1058194A]
IE2666/75A 1974-12-16 1975-12-09 Benzenedisulfonamides IE42203B1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US53335274A 1974-12-16 1974-12-16
US05/616,331 US4064239A (en) 1974-12-16 1975-09-26 Halogenated unsaturated alkyl benzenedisulfonamides as anthelmintics

Publications (2)

Publication Number Publication Date
IE42203L true IE42203L (en) 1976-06-16
IE42203B1 IE42203B1 (en) 1980-06-18

Family

ID=27064157

Family Applications (1)

Application Number Title Priority Date Filing Date
IE2666/75A IE42203B1 (en) 1974-12-16 1975-12-09 Benzenedisulfonamides

Country Status (16)

Country Link
AR (1) AR218216A1 (en)
CA (1) CA1058194A (en)
DE (1) DE2556122C2 (en)
DK (1) DK145756C (en)
FI (1) FI64799C (en)
FR (1) FR2294710A1 (en)
GB (1) GB1485897A (en)
IE (1) IE42203B1 (en)
IL (1) IL48610A (en)
LU (1) LU74019A1 (en)
NL (2) NL187394C (en)
NO (1) NO142667C (en)
NZ (1) NZ179477A (en)
OA (1) OA05183A (en)
PH (1) PH12041A (en)
SE (1) SE426817B (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107868024A (en) * 2017-10-25 2018-04-03 浙江海正药业股份有限公司 Crystal formation of MK-401 and its production and use
CN113773235B (en) * 2021-08-20 2022-06-17 北大方正集团有限公司 Synthesis method of clorsulon
CN116514868A (en) * 2022-01-20 2023-08-01 华创合成制药股份有限公司 Sulfonamide compound for treatment, preparation method and application thereof

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1483222A (en) * 1965-06-24 1967-06-02 Merck & Co Inc Production of new derivatives, substituted for nitrogen, of 5-chloro-2, 4-disulfamoylaniline
SE410598B (en) * 1973-05-11 1979-10-22 Merck & Co Inc PROCEDURE FOR THE PREPARATION OF PETROLE DISULPHONAMIDS WITH ANTHELMINTIC EFFECT

Also Published As

Publication number Publication date
IE42203B1 (en) 1980-06-18
FR2294710A1 (en) 1976-07-16
FI64799C (en) 1984-01-10
NL187394C (en) 1991-09-16
AU8743575A (en) 1977-06-16
NL930115I1 (en) 1993-10-18
SE426817B (en) 1983-02-14
CA1058194A (en) 1979-07-10
SE7513569L (en) 1976-06-17
IL48610A (en) 1979-10-31
OA05183A (en) 1981-01-31
FI753392A7 (en) 1976-06-17
NL187394B (en) 1991-04-16
NO142667B (en) 1980-06-16
NO754087L (en) 1976-06-17
NL7514163A (en) 1976-06-18
LU74019A1 (en) 1976-11-11
DK544775A (en) 1976-06-17
NZ179477A (en) 1978-04-03
DK145756B (en) 1983-02-21
DE2556122A1 (en) 1976-06-24
FI64799B (en) 1983-09-30
IL48610A0 (en) 1976-02-29
PH12041A (en) 1978-10-16
DK145756C (en) 1983-08-08
NO142667C (en) 1980-09-24
FR2294710B1 (en) 1979-09-21
GB1485897A (en) 1977-09-14
DE2556122C2 (en) 1986-05-22
AR218216A1 (en) 1980-05-30

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