IE42210L - 2-methoxy benzamides. - Google Patents

2-methoxy benzamides.

Info

Publication number
IE42210L
IE42210L IE752731A IE273175A IE42210L IE 42210 L IE42210 L IE 42210L IE 752731 A IE752731 A IE 752731A IE 273175 A IE273175 A IE 273175A IE 42210 L IE42210 L IE 42210L
Authority
IE
Ireland
Prior art keywords
carbon atoms
alkyl
hydrogen
dec
formula
Prior art date
Application number
IE752731A
Other versions
IE42210B1 (en
Original Assignee
Synthelabo
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FR7441718A external-priority patent/FR2294698A1/en
Priority claimed from FR7531334A external-priority patent/FR2327771A2/en
Priority claimed from FR7534570A external-priority patent/FR2331345A2/en
Application filed by Synthelabo filed Critical Synthelabo
Publication of IE42210L publication Critical patent/IE42210L/en
Publication of IE42210B1 publication Critical patent/IE42210B1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/24—Oxygen or sulfur atoms
    • C07D207/26—2-Pyrrolidones
    • C07D207/263—2-Pyrrolidones with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to other ring carbon atoms
    • C07D207/27—2-Pyrrolidones with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to other ring carbon atoms with substituted hydrocarbon radicals directly attached to the ring nitrogen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/08—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon radicals, substituted by hetero atoms, attached to ring carbon atoms
    • C07D207/09—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/20—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D211/26—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D211/70—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D211/72—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D211/74—Oxygen atoms
    • C07D211/76—Oxygen atoms attached in position 2 or 6

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pyrrole Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)

Abstract

1508880 2 - Methoxybenzamides SYNTHELABO 17 Dec 1975 [18 Dec 1974 14 Oct 1975 13 Nov 1975] 51635/75 Heading C2C Novel compounds (I) (including salts, racemates and isomers thereof) in which n is 1 or 2; R 1 represents a cycloalkylalkyl radical of formula (OH 2 ) m -CH-A-, a phenylalkyl radical of formula (in which m is an integer from 2 to 5, A is a linear or branched chain alkylene chain of 1 to 4 carbon atoms, and R 4 is hydrogen, halogen, trifluoromethyl, or alkyl or alkoxy of 1 to 3 carbon atoms), CNCH 2 -CH 2 -, CH=C-CH 2 -, or R 2 is chlorine, SO 2 R 5 (in which R 5 is alkyl of 1 to 4 carbon atoms), or SO 2 NR 6 R 7 (in which, R 6 and R 7 , which are identical or different, represent, independently of one another, hydrogen or alkyl of 1 to 4 carbon atoms); and R 3 is hydrogen or alkyl of 1 to 4 carbon atoms; are made by acylating amines (III) which are themselves obtained by reducing nitro compounds (IV) which are in turn prepared by reacting ketones (V) with MeNO 2 . Pharmaceutical preparations useful in treating nervous and psychosomatic disorders contain (I) as active ingredient. Administration is orally, parenterally or rectally. [GB1508880A]
IE2731/75A 1974-12-18 1975-12-15 2-methoxy-benzamide derivatives IE42210B1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR7441718A FR2294698A1 (en) 1974-12-18 1974-12-18 NEW DERIVATIVES OF 2-METHOXY BENZAMIDES SUBSTITUTE, THEIR SALTS, THEIR PREPARATION AND THE MEDICINAL PRODUCTS CONTAINING THEM
FR7531334A FR2327771A2 (en) 1975-10-14 1975-10-14 N-Heterocyclylmethy 12-methoxy-benzamides - useful for treating nervous and psychosomatic disorders (BE170676)
FR7534570A FR2331345A2 (en) 1975-11-13 1975-11-13 N-Heterocyclylmethy 12-methoxy-benzamides - useful for treating nervous and psychosomatic disorders (BE170676)

Publications (2)

Publication Number Publication Date
IE42210L true IE42210L (en) 1976-06-18
IE42210B1 IE42210B1 (en) 1980-06-18

Family

ID=27250393

Family Applications (1)

Application Number Title Priority Date Filing Date
IE2731/75A IE42210B1 (en) 1974-12-18 1975-12-15 2-methoxy-benzamide derivatives

Country Status (17)

Country Link
AT (1) AT353782B (en)
AU (1) AU497616B2 (en)
CA (1) CA1039731A (en)
CH (1) CH612668A5 (en)
DE (1) DE2556457C3 (en)
DK (1) DK574075A (en)
ES (2) ES443563A1 (en)
FI (1) FI753586A7 (en)
GB (1) GB1508880A (en)
GR (1) GR59205B (en)
IE (1) IE42210B1 (en)
IL (1) IL48678A (en)
LU (1) LU74026A1 (en)
MX (1) MX3180E (en)
NL (1) NL168219C (en)
NO (1) NO143625C (en)
SE (1) SE412908B (en)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4189495A (en) * 1974-09-17 1980-02-19 Synthelabo 2-Methoxy-benzamide derivatives
US4097481A (en) * 1976-11-08 1978-06-27 Riker Laboratories, Inc. Tertiary amide derivatives of pyrrolidine and piperidine
FR2415099A1 (en) * 1978-01-20 1979-08-17 Ile De France NEW DERIVATIVES OF 4-AMINO-5-ALKYLSULFONYL ORTHO-ANISAMIDES, THEIR METHODS OF PREPARATION AND THEIR APPLICATION AS PSYCHOTROPES
FR2440946A2 (en) * 1978-01-20 1980-06-06 Ile De France NOVEL SUBSTITUTED HETEROCYCLIC BENZAMIDES, PROCESSES FOR THEIR PREPARATION AND THEIR APPLICATION AS BEHAVIOR MODIFIERS
SE411118B (en) * 1978-03-23 1979-12-03 Astra Laekemedel Ab A PROCEDURE FOR THE PREPARATION OF 2,6-DIALCOXIBENSAMIDES WITH THERAPENTIC PROPERTIES
SE8101536L (en) * 1981-03-11 1982-09-12 Astra Laekemedel Ab Benzamide derivative
SE8205135D0 (en) * 1982-09-09 1982-09-09 Astra Laekemedel Ab Benzamido-DERIVATIVES
IL109422A0 (en) * 1993-04-30 1994-07-31 Shell Int Research N-benzyl heterocyclic compounds, process for their preparation and pesticidal compositions containing them
EP0623601A1 (en) * 1993-04-30 1994-11-09 Shell Internationale Researchmaatschappij B.V. N-(3-Fluorobenzyl)heterocyclic derivatives and their use as pesticides
CA2355296A1 (en) * 1998-12-11 2000-06-15 American Biogenetic Sciences, Inc. Substituted nitrogen heterocyclic compounds and therapeutic uses thereof

Also Published As

Publication number Publication date
CH612668A5 (en) 1979-08-15
ES457872A1 (en) 1978-03-01
ES443563A1 (en) 1977-08-16
ATA959075A (en) 1979-05-15
NO754284L (en) 1976-06-21
DE2556457C3 (en) 1981-02-12
DK574075A (en) 1976-06-19
SE7514143L (en) 1976-06-21
AU8764675A (en) 1977-06-23
NL168219B (en) 1981-10-16
MX3180E (en) 1980-06-11
NO143625B (en) 1980-12-08
NL168219C (en) 1982-03-16
GR59205B (en) 1977-11-26
IL48678A0 (en) 1976-02-29
NO143625C (en) 1981-03-18
DE2556457B2 (en) 1980-05-29
GB1508880A (en) 1978-04-26
IE42210B1 (en) 1980-06-18
AT353782B (en) 1979-12-10
SE412908B (en) 1980-03-24
CA1039731A (en) 1978-10-03
AU497616B2 (en) 1978-12-21
IL48678A (en) 1979-01-31
LU74026A1 (en) 1976-11-11
NL7514620A (en) 1976-06-22
DE2556457A1 (en) 1976-06-24
FI753586A7 (en) 1976-06-19

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