IE42759L - Compounds containing a ureido or iso-ureido grouping - Google Patents
Compounds containing a ureido or iso-ureido groupingInfo
- Publication number
- IE42759L IE42759L IE752578A IE257875A IE42759L IE 42759 L IE42759 L IE 42759L IE 752578 A IE752578 A IE 752578A IE 257875 A IE257875 A IE 257875A IE 42759 L IE42759 L IE 42759L
- Authority
- IE
- Ireland
- Prior art keywords
- ureido
- grouping
- iso
- compounds containing
- image
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title abstract 3
- 125000001951 carbamoylamino group Chemical group C(N)(=O)N* 0.000 title 1
- 230000003276 anti-hypertensive effect Effects 0.000 abstract 1
- 230000005494 condensation Effects 0.000 abstract 1
- 238000009833 condensation Methods 0.000 abstract 1
- CIDMUJMGDBSMQW-UHFFFAOYSA-N n-phenyl-4,5-dihydro-1,3-oxazol-2-amine Chemical class O1CCN=C1NC1=CC=CC=C1 CIDMUJMGDBSMQW-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C275/00—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
- C07C275/28—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
- C07C275/42—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton being further substituted by carboxyl groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C275/00—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
- C07C275/28—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
- C07C275/32—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton being further substituted by singly-bound oxygen atoms
- C07C275/34—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton being further substituted by singly-bound oxygen atoms having nitrogen atoms of urea groups and singly-bound oxygen atoms bound to carbon atoms of the same non-condensed six-membered aromatic ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
- C07D239/72—Quinazolines; Hydrogenated quinazolines
- C07D239/95—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in positions 2 and 4
- C07D239/96—Two oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
- C07D263/08—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D263/16—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D263/28—Nitrogen atoms not forming part of a nitro radical
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
The novel anilino-2-oxazolines of the general formula <IMAGE> in which R, Rf, X2, X5 and X6 have the meaning given in Claim 1, are prepared by intramolecular condensation of compounds of the general formula <IMAGE> in which Q1 is a reactive group. The novel compounds have antihypertensive action.
[GB1507340A]
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US52860374A | 1974-12-02 | 1974-12-02 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IE42759L true IE42759L (en) | 1976-06-02 |
| IE42759B1 IE42759B1 (en) | 1980-10-08 |
Family
ID=24106378
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IE2578/75A IE42759B1 (en) | 1974-12-02 | 1975-11-26 | Hydroxypolyhaloisopropyl substituted ureido-compounds |
Country Status (26)
| Country | Link |
|---|---|
| JP (1) | JPS5182239A (en) |
| AR (2) | AR219478A1 (en) |
| AT (1) | AT357557B (en) |
| AU (1) | AU501512B2 (en) |
| BE (1) | BE835899A (en) |
| CA (1) | CA1063112A (en) |
| CH (1) | CH623044A5 (en) |
| CS (1) | CS188259B2 (en) |
| DD (1) | DD124730A5 (en) |
| DE (1) | DE2552933A1 (en) |
| DK (1) | DK535275A (en) |
| FI (1) | FI753332A7 (en) |
| FR (1) | FR2346000A1 (en) |
| GB (1) | GB1507340A (en) |
| HU (1) | HU175541B (en) |
| IE (1) | IE42759B1 (en) |
| IL (1) | IL48557A (en) |
| IT (1) | IT1051024B (en) |
| LU (1) | LU73888A1 (en) |
| NL (1) | NL7513804A (en) |
| NO (1) | NO146497C (en) |
| PH (1) | PH14474A (en) |
| PL (2) | PL99122B1 (en) |
| SE (2) | SE7513331L (en) |
| SU (2) | SU655311A3 (en) |
| ZA (1) | ZA757457B (en) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS52111541A (en) * | 1976-02-19 | 1977-09-19 | Scherico Ltd | Substituted ureido compound and medical composition containing it as active ingredient |
| US4107303A (en) | 1976-06-24 | 1978-08-15 | E. I. Du Pont De Nemours And Company | Antihypertensive hexafluorohydroxyisopropyl benzazepines and benzazocines |
| DE2839462A1 (en) * | 1978-09-11 | 1980-03-27 | Basf Ag | AROYL UREAS |
| US6316503B1 (en) | 1999-03-15 | 2001-11-13 | Tularik Inc. | LXR modulators |
| DE60324104D1 (en) | 2002-01-30 | 2008-11-27 | Amgen Inc | Arylsulfonamidobenzylverbindungen |
| CA2474702A1 (en) | 2002-01-30 | 2003-08-07 | Tularik Inc | Heterocyclic arylsulfonamidobenzylic compounds |
| US20030199578A1 (en) * | 2002-04-19 | 2003-10-23 | Turner Sean C. | Naphthalene amides as potassium channel openers |
| CA2571356A1 (en) * | 2004-06-28 | 2006-01-05 | F. Hoffmann-La Roche Ag | Novel hexafluoroisopropanol derivatives |
| RU2712163C2 (en) * | 2014-10-24 | 2020-01-24 | Оно Фармасьютикал Ко., Лтд. | Activator of kcnq2-5 channels |
| JP6197971B1 (en) * | 2016-04-22 | 2017-09-20 | 小野薬品工業株式会社 | KCNQ2-5 channel-related disease prevention and / or treatment agent |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3453284A (en) * | 1966-01-19 | 1969-07-01 | Du Pont | Certain 2-(substituted-anilino)-2-oxazolines |
| DE1670751A1 (en) * | 1966-09-27 | 1970-12-23 | Bayer Ag | Process for the preparation of 2-phenylamino-2-oxazolines |
| FR1543534A (en) * | 1966-09-27 | 1968-10-25 | Bayer Ag | Manufacturing process of 2-phenylimino-oxazolidines |
| DE1670752A1 (en) * | 1966-09-27 | 1970-12-23 | Bayer Ag | Process for the preparation of 2-phenylamino-oxazolines |
| FR1543535A (en) * | 1966-09-27 | 1968-10-25 | Bayer Ag | Manufacturing process of 2-phenylamino-2-oxazolines |
-
1975
- 1975-11-21 CH CH1516475A patent/CH623044A5/en not_active IP Right Cessation
- 1975-11-25 BE BE162139A patent/BE835899A/en unknown
- 1975-11-26 NO NO753984A patent/NO146497C/en unknown
- 1975-11-26 ZA ZA757457A patent/ZA757457B/en unknown
- 1975-11-26 SE SE7513331A patent/SE7513331L/en not_active Application Discontinuation
- 1975-11-26 IE IE2578/75A patent/IE42759B1/en unknown
- 1975-11-26 AT AT898575A patent/AT357557B/en not_active IP Right Cessation
- 1975-11-26 GB GB48640/75A patent/GB1507340A/en not_active Expired
- 1975-11-26 CA CA240,512A patent/CA1063112A/en not_active Expired
- 1975-11-26 FI FI753332A patent/FI753332A7/fi not_active Application Discontinuation
- 1975-11-26 DE DE19752552933 patent/DE2552933A1/en not_active Withdrawn
- 1975-11-26 NL NL7513804A patent/NL7513804A/en not_active Application Discontinuation
- 1975-11-26 PH PH17810A patent/PH14474A/en unknown
- 1975-11-26 FR FR7536178A patent/FR2346000A1/en active Granted
- 1975-11-26 AR AR261362A patent/AR219478A1/en active
- 1975-11-26 AU AU86989/75A patent/AU501512B2/en not_active Ceased
- 1975-11-27 LU LU73888A patent/LU73888A1/xx unknown
- 1975-11-27 JP JP50141811A patent/JPS5182239A/ja active Pending
- 1975-11-27 IL IL48557A patent/IL48557A/en unknown
- 1975-11-27 DK DK535275A patent/DK535275A/en not_active Application Discontinuation
- 1975-12-01 CS CS758133A patent/CS188259B2/en unknown
- 1975-12-01 HU HU75SCHE549A patent/HU175541B/en unknown
- 1975-12-01 DD DD189793A patent/DD124730A5/xx unknown
- 1975-12-01 SU SU752194050A patent/SU655311A3/en active
- 1975-12-01 PL PL1975185156A patent/PL99122B1/en unknown
- 1975-12-01 PL PL1975193580A patent/PL102327B1/en unknown
- 1975-12-02 IT IT29923/75A patent/IT1051024B/en active
-
1976
- 1976-10-20 AR AR265154A patent/AR218436A1/en active
- 1976-10-26 SU SU762414458A patent/SU685146A3/en active
-
1980
- 1980-06-11 SE SE8004364A patent/SE8004364L/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| IL48557A0 (en) | 1976-01-30 |
| DE2552933A1 (en) | 1976-06-10 |
| HU175541B (en) | 1980-08-28 |
| PL102327B1 (en) | 1979-03-31 |
| SU685146A3 (en) | 1979-09-05 |
| NO146497C (en) | 1982-10-13 |
| GB1507340A (en) | 1978-04-12 |
| AT357557B (en) | 1980-07-25 |
| CS188259B2 (en) | 1979-02-28 |
| JPS5182239A (en) | 1976-07-19 |
| AR219478A1 (en) | 1980-08-29 |
| CA1063112A (en) | 1979-09-25 |
| CH623044A5 (en) | 1981-05-15 |
| BE835899A (en) | 1976-05-25 |
| ZA757457B (en) | 1976-11-24 |
| PL99122B1 (en) | 1978-06-30 |
| IT1051024B (en) | 1981-04-21 |
| SE8004364L (en) | 1980-06-11 |
| SU655311A3 (en) | 1979-03-30 |
| AR218436A1 (en) | 1980-06-13 |
| IE42759B1 (en) | 1980-10-08 |
| DD124730A5 (en) | 1977-03-09 |
| NL7513804A (en) | 1976-06-04 |
| DK535275A (en) | 1976-06-03 |
| FR2346000B1 (en) | 1978-11-17 |
| FR2346000A1 (en) | 1977-10-28 |
| FI753332A7 (en) | 1976-06-03 |
| AU501512B2 (en) | 1979-06-21 |
| LU73888A1 (en) | 1976-09-06 |
| SE7513331L (en) | 1976-06-03 |
| AU8698975A (en) | 1977-06-02 |
| IL48557A (en) | 1979-05-31 |
| PH14474A (en) | 1981-08-07 |
| ATA898575A (en) | 1979-12-15 |
| NO753984L (en) | 1976-06-03 |
| NO146497B (en) | 1982-07-05 |
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