IE42759L - Compounds containing a ureido or iso-ureido grouping - Google Patents

Compounds containing a ureido or iso-ureido grouping

Info

Publication number
IE42759L
IE42759L IE752578A IE257875A IE42759L IE 42759 L IE42759 L IE 42759L IE 752578 A IE752578 A IE 752578A IE 257875 A IE257875 A IE 257875A IE 42759 L IE42759 L IE 42759L
Authority
IE
Ireland
Prior art keywords
ureido
grouping
iso
compounds containing
image
Prior art date
Application number
IE752578A
Other versions
IE42759B1 (en
Original Assignee
Scherico Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Scherico Ltd filed Critical Scherico Ltd
Publication of IE42759L publication Critical patent/IE42759L/en
Publication of IE42759B1 publication Critical patent/IE42759B1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C275/00—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C275/28—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
    • C07C275/42—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton being further substituted by carboxyl groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C275/00—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C275/28—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
    • C07C275/32—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton being further substituted by singly-bound oxygen atoms
    • C07C275/34—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton being further substituted by singly-bound oxygen atoms having nitrogen atoms of urea groups and singly-bound oxygen atoms bound to carbon atoms of the same non-condensed six-membered aromatic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • C07D239/72—Quinazolines; Hydrogenated quinazolines
    • C07D239/95—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in positions 2 and 4
    • C07D239/96—Two oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/08—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D263/16—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D263/28—Nitrogen atoms not forming part of a nitro radical

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

The novel anilino-2-oxazolines of the general formula <IMAGE> in which R, Rf, X2, X5 and X6 have the meaning given in Claim 1, are prepared by intramolecular condensation of compounds of the general formula <IMAGE> in which Q1 is a reactive group. The novel compounds have antihypertensive action. [GB1507340A]
IE2578/75A 1974-12-02 1975-11-26 Hydroxypolyhaloisopropyl substituted ureido-compounds IE42759B1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US52860374A 1974-12-02 1974-12-02

Publications (2)

Publication Number Publication Date
IE42759L true IE42759L (en) 1976-06-02
IE42759B1 IE42759B1 (en) 1980-10-08

Family

ID=24106378

Family Applications (1)

Application Number Title Priority Date Filing Date
IE2578/75A IE42759B1 (en) 1974-12-02 1975-11-26 Hydroxypolyhaloisopropyl substituted ureido-compounds

Country Status (26)

Country Link
JP (1) JPS5182239A (en)
AR (2) AR219478A1 (en)
AT (1) AT357557B (en)
AU (1) AU501512B2 (en)
BE (1) BE835899A (en)
CA (1) CA1063112A (en)
CH (1) CH623044A5 (en)
CS (1) CS188259B2 (en)
DD (1) DD124730A5 (en)
DE (1) DE2552933A1 (en)
DK (1) DK535275A (en)
FI (1) FI753332A7 (en)
FR (1) FR2346000A1 (en)
GB (1) GB1507340A (en)
HU (1) HU175541B (en)
IE (1) IE42759B1 (en)
IL (1) IL48557A (en)
IT (1) IT1051024B (en)
LU (1) LU73888A1 (en)
NL (1) NL7513804A (en)
NO (1) NO146497C (en)
PH (1) PH14474A (en)
PL (2) PL99122B1 (en)
SE (2) SE7513331L (en)
SU (2) SU655311A3 (en)
ZA (1) ZA757457B (en)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS52111541A (en) * 1976-02-19 1977-09-19 Scherico Ltd Substituted ureido compound and medical composition containing it as active ingredient
US4107303A (en) 1976-06-24 1978-08-15 E. I. Du Pont De Nemours And Company Antihypertensive hexafluorohydroxyisopropyl benzazepines and benzazocines
DE2839462A1 (en) * 1978-09-11 1980-03-27 Basf Ag AROYL UREAS
US6316503B1 (en) 1999-03-15 2001-11-13 Tularik Inc. LXR modulators
AU2003208952B2 (en) 2002-01-30 2008-04-24 Amgen Inc. Heterocyclic arylsulfonamidobenzylic compounds
CA2474433A1 (en) 2002-01-30 2003-08-07 Tularik Inc. Arylsulfonamidobenzylic compounds
US20030199578A1 (en) * 2002-04-19 2003-10-23 Turner Sean C. Naphthalene amides as potassium channel openers
MXPA06014807A (en) * 2004-06-28 2007-02-12 Hoffmann La Roche Novel hexafluoroisopropanol derivatives.
JP6217866B2 (en) * 2014-10-24 2017-10-25 小野薬品工業株式会社 KCNQ2-5 channel activator
JP6197971B1 (en) * 2016-04-22 2017-09-20 小野薬品工業株式会社 KCNQ2-5 channel-related disease prevention and / or treatment agent

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3453284A (en) * 1966-01-19 1969-07-01 Du Pont Certain 2-(substituted-anilino)-2-oxazolines
FR1543535A (en) * 1966-09-27 1968-10-25 Bayer Ag Manufacturing process of 2-phenylamino-2-oxazolines
DE1670751A1 (en) * 1966-09-27 1970-12-23 Bayer Ag Process for the preparation of 2-phenylamino-2-oxazolines
FR1543534A (en) * 1966-09-27 1968-10-25 Bayer Ag Manufacturing process of 2-phenylimino-oxazolidines
DE1670752A1 (en) * 1966-09-27 1970-12-23 Bayer Ag Process for the preparation of 2-phenylamino-oxazolines

Also Published As

Publication number Publication date
AR219478A1 (en) 1980-08-29
AR218436A1 (en) 1980-06-13
HU175541B (en) 1980-08-28
PL99122B1 (en) 1978-06-30
IE42759B1 (en) 1980-10-08
DK535275A (en) 1976-06-03
PH14474A (en) 1981-08-07
FR2346000B1 (en) 1978-11-17
SE7513331L (en) 1976-06-03
DE2552933A1 (en) 1976-06-10
JPS5182239A (en) 1976-07-19
LU73888A1 (en) 1976-09-06
FI753332A7 (en) 1976-06-03
ATA898575A (en) 1979-12-15
NO753984L (en) 1976-06-03
SE8004364L (en) 1980-06-11
SU655311A3 (en) 1979-03-30
CA1063112A (en) 1979-09-25
CH623044A5 (en) 1981-05-15
NO146497C (en) 1982-10-13
NL7513804A (en) 1976-06-04
AT357557B (en) 1980-07-25
GB1507340A (en) 1978-04-12
BE835899A (en) 1976-05-25
ZA757457B (en) 1976-11-24
IL48557A (en) 1979-05-31
DD124730A5 (en) 1977-03-09
NO146497B (en) 1982-07-05
IT1051024B (en) 1981-04-21
SU685146A3 (en) 1979-09-05
IL48557A0 (en) 1976-01-30
PL102327B1 (en) 1979-03-31
AU8698975A (en) 1977-06-02
FR2346000A1 (en) 1977-10-28
CS188259B2 (en) 1979-02-28
AU501512B2 (en) 1979-06-21

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