IE43083L - Sustained release formulations - Google Patents
Sustained release formulationsInfo
- Publication number
- IE43083L IE43083L IE760508A IE50876A IE43083L IE 43083 L IE43083 L IE 43083L IE 760508 A IE760508 A IE 760508A IE 50876 A IE50876 A IE 50876A IE 43083 L IE43083 L IE 43083L
- Authority
- IE
- Ireland
- Prior art keywords
- sustained release
- mixture
- weight
- gastric juice
- formulation
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title abstract 5
- 238000009472 formulation Methods 0.000 title abstract 3
- 238000013268 sustained release Methods 0.000 title abstract 2
- 239000012730 sustained-release form Substances 0.000 title abstract 2
- 210000004051 gastric juice Anatomy 0.000 abstract 2
- 239000008240 homogeneous mixture Substances 0.000 abstract 2
- 239000000416 hydrocolloid Substances 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 239000000463 material Substances 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 239000007787 solid Substances 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/0065—Forms with gastric retention, e.g. floating on gastric juice, adhering to gastric mucosa, expanding to prevent passage through the pylorus
Landscapes
- Health & Medical Sciences (AREA)
- Nutrition Science (AREA)
- Physiology (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Solid pharmaceutical formulations are described which have a sustained release effect and which are buoyant in gastric juice. The formulation is present in the form of a homogeneous mixture. This mixture contains at least one therapeutic active compound, up to 80% by weight of therapeutically inert, pharmaceutically acceptable auxiliary substances, up to 60% by weight of a fatty material having a specific weight less than 1 and such a proportion of a hydrocolloid or of a mixture of hydrocolloids, incorporated into the formulation essentially in the dry form, that, after contact with the gastric juice, a layer which is impermeable to water is generated on the surface of this homogeneous mixture.
[GB1546448A]
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US55910775A | 1975-03-17 | 1975-03-17 | |
| US65800376A | 1976-02-13 | 1976-02-13 | |
| KR7600645A KR800001387B1 (en) | 1975-03-17 | 1976-03-16 | Process for preparing sustained release formulation |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IE43083L true IE43083L (en) | 1976-09-17 |
| IE43083B1 IE43083B1 (en) | 1980-12-17 |
Family
ID=27348140
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IE508/76A IE43083B1 (en) | 1975-03-17 | 1976-03-11 | Substained-release formulations |
Country Status (21)
| Country | Link |
|---|---|
| JP (1) | JPS51115910A (en) |
| AR (1) | AR222624A1 (en) |
| AT (1) | AT353415B (en) |
| AU (1) | AU505355B2 (en) |
| CA (1) | CA1073358A (en) |
| CH (1) | CH630257A5 (en) |
| DD (1) | DD124102A5 (en) |
| DE (1) | DE2611041A1 (en) |
| DK (1) | DK148344C (en) |
| ES (1) | ES446075A1 (en) |
| FR (1) | FR2304354A1 (en) |
| GB (1) | GB1546448A (en) |
| GR (1) | GR60341B (en) |
| IE (1) | IE43083B1 (en) |
| LU (1) | LU74558A1 (en) |
| MC (1) | MC1101A1 (en) |
| NL (1) | NL190313C (en) |
| NZ (1) | NZ180321A (en) |
| PH (1) | PH14927A (en) |
| PT (1) | PT64907B (en) |
| SE (1) | SE433804B (en) |
Families Citing this family (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NZ197543A (en) * | 1980-07-02 | 1984-12-14 | Commw Scient Ind Res Org | Controlled release compositions for inclusion in intraruminal devices |
| CH649215A5 (en) * | 1981-04-29 | 1985-05-15 | Hoffmann La Roche | PHARMACEUTICAL PREPARATIONS. |
| CH652025A5 (en) * | 1981-09-14 | 1985-10-31 | Hoffmann La Roche | Pharmaceutical preparation. |
| US4421736A (en) * | 1982-05-20 | 1983-12-20 | Merrel Dow Pharmaceuticals Inc. | Sustained release diethylpropion compositions |
| CH666406A5 (en) * | 1984-02-29 | 1988-07-29 | Sandoz Ag | METHOD FOR PRODUCING microcapsules BROMOKRIPTINMESYLAT AS PHARMACOLOGICAL ACTIVE INCLUDED. |
| GB2154874B (en) * | 1984-02-29 | 1987-11-04 | Sandoz Ltd | Bromoscriptine compositions |
| AU4064285A (en) * | 1984-03-21 | 1985-10-11 | American Home Products Corporation | Sustained release pharmaceutical capsules |
| JPS6143108A (en) * | 1984-08-03 | 1986-03-01 | Nippon Shinyaku Co Ltd | Medicinal drug and its preparation |
| HU195729B (en) * | 1985-02-05 | 1988-07-28 | Sandoz Ag | Process for producing pharmaceutical compositions containing 9,10-dihydro-ergot-alkaloides |
| GB8524135D0 (en) * | 1985-10-01 | 1985-11-06 | Sandoz Ltd | Darodipine compositions |
| NL194822C (en) * | 1985-10-01 | 2003-04-03 | Novartis Ag | Preparation for oral administration with controlled release and method for its preparation. |
| US4786503A (en) * | 1987-04-06 | 1988-11-22 | Alza Corporation | Dosage form comprising parallel lamine |
| US4814178A (en) * | 1987-07-01 | 1989-03-21 | Sanford Bolton | Floating sustained release therapeutic compositions |
| US5133974A (en) * | 1989-05-05 | 1992-07-28 | Kv Pharmaceutical Company | Extended release pharmaceutical formulations |
| IE64128B1 (en) * | 1990-02-26 | 1995-07-12 | Byrne Rynne Holdings Ltd | A pharmaceutical composition |
| MY110880A (en) * | 1991-01-30 | 1999-06-30 | The Wellcome Foundation Ltd | Water-dispersible tablets |
| US5629016A (en) * | 1991-01-30 | 1997-05-13 | Glaxo Wellcome Inc. | Water-dispersible tablets |
| US5498422A (en) * | 1991-04-08 | 1996-03-12 | Nippon Shinyaku Company Limited | Sustained release capsule |
| ES2124303T3 (en) * | 1992-03-25 | 1999-02-01 | Depomed Inc | DOSAGE FORMS OF DELAYED DELIVERY ORAL DRUGS BASED ON HYDROXYETHYL CELLULOSE. |
| US5698226A (en) * | 1993-07-13 | 1997-12-16 | Glaxo Wellcome Inc. | Water-dispersible tablets |
| CA2175225C (en) * | 1993-10-29 | 2004-09-21 | Keith Graeme Hutchison | Gelatin capsule fill able to foam |
| US5888540A (en) * | 1993-10-29 | 1999-03-30 | Sugden; Keith | Pharmaceutical products |
| WO1995011668A1 (en) * | 1993-10-29 | 1995-05-04 | Reckitt & Colman Products Limited | Gelatin capsule fill able to foam |
| WO1995031186A1 (en) * | 1994-05-13 | 1995-11-23 | Smithkline Beecham Corporation | Method and composition for increasing calcium uptake |
| CA2205351A1 (en) * | 1994-12-01 | 1996-06-06 | Cibus Pharmaceutical, Inc. | Sustained-release drug delivery employing a powdered hydrocolloid gum obtainable from higher plants |
| FR2820318B1 (en) * | 2001-02-08 | 2005-12-23 | Ellipse Pharmaceuticals | METHOD FOR MANUFACTURING A FLOATING COMPRESSOR INCLUDING AN ACTIVE INGREDIENT AND A COMPRESS OBTAINED |
| FR2820319B3 (en) * | 2001-02-08 | 2003-12-05 | Ellipse Pharmaceuticals | PROCESS FOR PRODUCING A FLOATING TABLET INCLUDING ALFUZOSINE AND TABLET OBTAINED |
| EP1245227A1 (en) * | 2001-03-31 | 2002-10-02 | Jagotec Ag | A pharmaceutical tablet system that floats in the stomach for programmed release of active substance and process of producing buoyant material contained in same |
| FR2874325B1 (en) * | 2004-08-19 | 2006-10-20 | Sanofi Synthelabo | PHARMACEUTICAL COMPOSITION IN THE FORM OF A GASTRIC RESISTANCE COMPRESSOR CONTAINING ALFUZOSIN |
| WO2026022379A1 (en) * | 2024-07-26 | 2026-01-29 | Inkvivo Technologies Sa | Gastroretentive formulations |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE1059624B (en) * | 1954-11-11 | 1959-06-18 | Dr Knut Jacobus Sundman | Process for the production of medicaments dispersed in a carrier substance in dosed form |
| JPS5512411B2 (en) * | 1974-03-12 | 1980-04-02 | ||
| DE2439538C3 (en) * | 1974-08-17 | 1980-07-17 | Ludwig Heumann & Co Gmbh, 8500 Nuernberg | Process for the manufacture of orally administered drugs with delayed release of action |
-
1976
- 1976-03-05 CH CH277676A patent/CH630257A5/en not_active IP Right Cessation
- 1976-03-11 IE IE508/76A patent/IE43083B1/en unknown
- 1976-03-15 MC MC761182A patent/MC1101A1/en unknown
- 1976-03-15 FR FR7607363A patent/FR2304354A1/en active Granted
- 1976-03-15 GR GR50306A patent/GR60341B/en unknown
- 1976-03-15 NZ NZ180321A patent/NZ180321A/en unknown
- 1976-03-15 LU LU74558A patent/LU74558A1/xx unknown
- 1976-03-16 ES ES446075A patent/ES446075A1/en not_active Expired
- 1976-03-16 AU AU12049/76A patent/AU505355B2/en not_active Expired
- 1976-03-16 SE SE7603325A patent/SE433804B/en not_active IP Right Cessation
- 1976-03-16 DE DE19762611041 patent/DE2611041A1/en active Granted
- 1976-03-16 DK DK113676A patent/DK148344C/en not_active IP Right Cessation
- 1976-03-16 DD DD191877A patent/DD124102A5/xx unknown
- 1976-03-16 CA CA248,018A patent/CA1073358A/en not_active Expired
- 1976-03-16 PT PT64907A patent/PT64907B/en unknown
- 1976-03-16 GB GB10482/76A patent/GB1546448A/en not_active Expired
- 1976-03-16 AT AT192276A patent/AT353415B/en not_active IP Right Cessation
- 1976-03-16 JP JP51027758A patent/JPS51115910A/en active Granted
- 1976-03-17 AR AR262597A patent/AR222624A1/en active
- 1976-03-17 NL NLAANVRAGE7602776,A patent/NL190313C/en not_active IP Right Cessation
- 1976-03-29 PH PH18224A patent/PH14927A/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| ES446075A1 (en) | 1977-09-16 |
| LU74558A1 (en) | 1977-09-27 |
| DD124102A5 (en) | 1977-02-02 |
| ATA192276A (en) | 1979-04-15 |
| DE2611041A1 (en) | 1976-10-14 |
| CH630257A5 (en) | 1982-06-15 |
| JPS638084B2 (en) | 1988-02-19 |
| FR2304354A1 (en) | 1976-10-15 |
| AU1204976A (en) | 1977-09-22 |
| AU505355B2 (en) | 1979-11-15 |
| CA1073358A (en) | 1980-03-11 |
| AR222624A1 (en) | 1981-06-15 |
| NL7602776A (en) | 1976-09-21 |
| PH14927A (en) | 1982-01-29 |
| AT353415B (en) | 1979-11-12 |
| SE7603325L (en) | 1976-09-18 |
| NL190313C (en) | 1994-01-17 |
| PT64907B (en) | 1978-03-24 |
| DK148344B (en) | 1985-06-17 |
| MC1101A1 (en) | 1977-02-04 |
| FR2304354B1 (en) | 1979-04-27 |
| GB1546448A (en) | 1979-05-23 |
| PT64907A (en) | 1976-04-01 |
| IE43083B1 (en) | 1980-12-17 |
| JPS51115910A (en) | 1976-10-13 |
| DE2611041C2 (en) | 1988-06-09 |
| DK148344C (en) | 1985-11-04 |
| NZ180321A (en) | 1978-06-20 |
| NL190313B (en) | 1993-08-16 |
| SE433804B (en) | 1984-06-18 |
| GR60341B (en) | 1978-05-17 |
| DK113676A (en) | 1976-09-18 |
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