IE43409L - N-alkyl imidazoles - Google Patents
N-alkyl imidazolesInfo
- Publication number
- IE43409L IE43409L IE761651A IE165176A IE43409L IE 43409 L IE43409 L IE 43409L IE 761651 A IE761651 A IE 761651A IE 165176 A IE165176 A IE 165176A IE 43409 L IE43409 L IE 43409L
- Authority
- IE
- Ireland
- Prior art keywords
- phenyl
- compounds
- alkyl
- formula
- image
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/645—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having two nitrogen atoms as the only ring hetero atoms
- C07F9/6503—Five-membered rings
- C07F9/6506—Five-membered rings having the nitrogen atoms in positions 1 and 3
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Communicable Diseases (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Oncology (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Abstract
The compounds correspond to the formula: <IMAGE> in which R<1> and R<2> denote phenyl, phenyl-lower alkyl or phenyl-lower alkenyl and the phenyl rings can be alkyl-, halogen- or trifluoromethyl-substituted, X represents oxygen or sulphur and n = 1 to 8. They are prepared by etherification of corresponding compounds of the formula: <IMAGE> in which A represents hydroxyl or a leaving group (Y), with a compound R<2>Y or R<2>OH or R<2>SH. The compounds and their salts are distinguished by fungicidal, antibacterial and antiprotozoal action; they can be used in the corresponding therapeutic indications.
[GB1522717A]
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US59961875A | 1975-07-28 | 1975-07-28 | |
| US66502376A | 1976-03-08 | 1976-03-08 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IE43409L true IE43409L (en) | 1977-01-28 |
| IE43409B1 IE43409B1 (en) | 1981-02-25 |
Family
ID=27083399
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IE1651/76A IE43409B1 (en) | 1975-07-28 | 1976-07-26 | Derivatives of substitued n-alkyl imidazoles having pharmaceutical activity |
Country Status (14)
| Country | Link |
|---|---|
| JP (1) | JPS6028820B2 (en) |
| AU (1) | AU505298B2 (en) |
| CH (2) | CH621117A5 (en) |
| DE (1) | DE2633492A1 (en) |
| ES (2) | ES461980A1 (en) |
| FR (1) | FR2319348A1 (en) |
| GB (1) | GB1522717A (en) |
| HK (1) | HK8480A (en) |
| IE (1) | IE43409B1 (en) |
| MX (1) | MX3866E (en) |
| MY (1) | MY8000271A (en) |
| NL (1) | NL183760C (en) |
| NZ (1) | NZ181567A (en) |
| PH (1) | PH14563A (en) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE443783B (en) * | 1977-01-10 | 1986-03-10 | Syntex Inc | SET TO PREPARE 1- / 2- (HALOPHENYLTIO) -4- (P-CHLORO-OR-FLUORPHENYL) -N-BUTYL / -IMIDAZOLES |
| US4213991A (en) * | 1978-05-30 | 1980-07-22 | Syntex (U.S.A.) Inc. | Derivatives of substituted N-alkyl imidazoles and compositions and methods containing the same |
| DE2845254A1 (en) * | 1978-10-18 | 1980-05-08 | Basf Ag | GAMMA AZOLYL COMPOUNDS |
| EP0013786B1 (en) * | 1979-01-22 | 1982-10-06 | Syntex (U.S.A.) Inc. | Imidazole derivatives, pharmaceutical compositions containing them and their preparation |
| DE2912288A1 (en) * | 1979-03-28 | 1980-10-09 | Bayer Ag | METHOD FOR PRODUCING HYDROXYETHYL AZOLES |
| JPS55160767A (en) * | 1979-05-31 | 1980-12-13 | Idota Yutaka | Imidazole derivative |
| CA1155853A (en) * | 1980-06-06 | 1983-10-25 | Joseph A. Martin | Imidazole derivatives and preparation thereof |
| DE3369984D1 (en) * | 1982-07-12 | 1987-04-09 | Searle & Co | 1-(1h-imidazolyl), 1-n-morpholinyl and pyridyl compounds, their preparation and pharmaceutical compositions containing them |
| JPS6068220A (en) * | 1983-09-24 | 1985-04-18 | 株式会社マキ製作所 | Automatic mounting method and device for fruit cap |
| JPH03115267A (en) * | 1989-09-28 | 1991-05-16 | Maruho Kk | Propiophenone derivative, its production and central muscle relaxant and antispasmodic agent containing the same |
| CA2898610C (en) * | 2013-01-21 | 2021-01-19 | Osaka University | Phenoxyalkylamine compound |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SU557755A3 (en) * | 1968-08-19 | 1977-05-05 | Янссен Фармасьютика Н.В. (Фирма) | Method for preparing imidazole derivatives |
| US3658813A (en) * | 1970-01-13 | 1972-04-25 | Janssen Pharmaceutica Nv | 1-(beta-aryl-beta-(r-oxy)-ethyl)-imidazoles |
| DE2041771C3 (en) * | 1970-08-22 | 1979-07-26 | Bayer Ag, 5090 Leverkusen | derivatives |
-
1976
- 1976-07-16 MX MX761776U patent/MX3866E/en unknown
- 1976-07-22 GB GB30685/76A patent/GB1522717A/en not_active Expired
- 1976-07-26 IE IE1651/76A patent/IE43409B1/en unknown
- 1976-07-26 AU AU16222/76A patent/AU505298B2/en not_active Expired
- 1976-07-26 DE DE19762633492 patent/DE2633492A1/en active Granted
- 1976-07-26 NZ NZ181567A patent/NZ181567A/en unknown
- 1976-07-26 FR FR7622761A patent/FR2319348A1/en active Granted
- 1976-07-27 NL NLAANVRAGE7608297,A patent/NL183760C/en not_active IP Right Cessation
- 1976-07-27 JP JP51089590A patent/JPS6028820B2/en not_active Expired
- 1976-07-27 PH PH18726A patent/PH14563A/en unknown
- 1976-07-28 CH CH967376A patent/CH621117A5/en not_active IP Right Cessation
-
1977
- 1977-08-30 ES ES461980A patent/ES461980A1/en not_active Expired
- 1977-08-30 ES ES461979A patent/ES461979A1/en not_active Expired
-
1980
- 1980-03-06 HK HK84/80A patent/HK8480A/en unknown
- 1980-05-06 CH CH352280A patent/CH623040A5/en not_active IP Right Cessation
- 1980-12-30 MY MY271/80A patent/MY8000271A/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| GB1522717A (en) | 1978-08-23 |
| ES461979A1 (en) | 1978-12-01 |
| NL183760C (en) | 1989-01-16 |
| PH14563A (en) | 1981-09-24 |
| CH623040A5 (en) | 1981-05-15 |
| FR2319348A1 (en) | 1977-02-25 |
| DE2633492A1 (en) | 1977-02-24 |
| MX3866E (en) | 1981-08-26 |
| JPS5217472A (en) | 1977-02-09 |
| IE43409B1 (en) | 1981-02-25 |
| AU505298B2 (en) | 1979-11-15 |
| NL183760B (en) | 1988-08-16 |
| DE2633492C2 (en) | 1990-10-25 |
| NZ181567A (en) | 1978-04-28 |
| CH621117A5 (en) | 1981-01-15 |
| FR2319348B1 (en) | 1979-07-13 |
| AU1622276A (en) | 1978-02-02 |
| MY8000271A (en) | 1980-12-31 |
| HK8480A (en) | 1980-03-14 |
| ES461980A1 (en) | 1978-06-01 |
| JPS6028820B2 (en) | 1985-07-06 |
| NL7608297A (en) | 1977-02-01 |
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