IE43778L - Solid solutions of ergot alkaloids in polymers - Google Patents

Solid solutions of ergot alkaloids in polymers

Info

Publication number
IE43778L
IE43778L IE762282A IE228276A IE43778L IE 43778 L IE43778 L IE 43778L IE 762282 A IE762282 A IE 762282A IE 228276 A IE228276 A IE 228276A IE 43778 L IE43778 L IE 43778L
Authority
IE
Ireland
Prior art keywords
polymers
solid solutions
ergot alkaloids
preparation
solid material
Prior art date
Application number
IE762282A
Other versions
IE43778B1 (en
Original Assignee
Sandoz Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz Ltd filed Critical Sandoz Ltd
Publication of IE43778L publication Critical patent/IE43778L/en
Publication of IE43778B1 publication Critical patent/IE43778B1/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • A61K31/48Ergoline derivatives, e.g. lysergic acid, ergotamine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/146Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/02Drugs for disorders of the nervous system for peripheral neuropathies

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Neurosurgery (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

The invention relates to a process for the preparation of a solid material composed of ergot peptide alkaloids, their hydrogenated forms or their salts and polyvinylpyrrolidone. The solid material obtained according to the invention can be used for the preparation of pharmaceutical compositions. [GB1560406A]
IE2282/76A 1975-10-17 1976-10-15 Solid solutions of ergot alkaloids in polymers IE43778B1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE2546577A DE2546577B2 (en) 1975-10-17 1975-10-17 Solid substances made from polyvinylpyrrolidone and ergot alkaloids

Publications (2)

Publication Number Publication Date
IE43778L true IE43778L (en) 1977-04-17
IE43778B1 IE43778B1 (en) 1981-05-20

Family

ID=5959411

Family Applications (1)

Application Number Title Priority Date Filing Date
IE2282/76A IE43778B1 (en) 1975-10-17 1976-10-15 Solid solutions of ergot alkaloids in polymers

Country Status (28)

Country Link
JP (1) JPS5854122B2 (en)
AT (1) AT362510B (en)
AU (1) AU508628B2 (en)
BE (1) BE847368A (en)
CA (1) CA1079641A (en)
CH (1) CH643737A5 (en)
CS (1) CS199647B2 (en)
DE (1) DE2546577B2 (en)
DK (1) DK146194C (en)
ES (1) ES452420A1 (en)
FI (1) FI762875A7 (en)
FR (1) FR2327764A1 (en)
GB (1) GB1560406A (en)
GR (1) GR61268B (en)
HK (1) HK3183A (en)
HU (1) HU172533B (en)
IE (1) IE43778B1 (en)
IL (1) IL50686A (en)
MY (1) MY8400063A (en)
NL (1) NL184558C (en)
NO (1) NO144468C (en)
NZ (1) NZ182341A (en)
PH (1) PH14513A (en)
PT (1) PT65719B (en)
SE (1) SE430379B (en)
SG (1) SG63082G (en)
SU (1) SU1165223A3 (en)
ZA (1) ZA766166B (en)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1572226A (en) * 1977-11-03 1980-07-30 Hoechst Uk Ltd Pharmaceutical preparations in solid unit dosage form
FI793888A7 (en) * 1978-12-21 1981-01-01 Sandoz Ag Galenic mixtures.
US4411882A (en) 1978-12-21 1983-10-25 Sandoz Ltd. Galenical compositions
FR2454804B1 (en) * 1979-04-26 1986-11-21 Sanofi Sa DIHYDROERGOTOXIN-BASED MEDICINAL PRODUCT AND PROCESS FOR PREPARING THE SAME
US4366145A (en) * 1981-06-24 1982-12-28 Sandoz, Inc. Soft gelatin capsule with a liquid ergot alkaloid center fill solution and method of preparation
US4898729A (en) * 1983-12-09 1990-02-06 Euroceltique, S.A. Treatment of hypertension, compounds and compositions for antihypertension and diuresis
NL194389C (en) * 1984-06-14 2002-03-04 Novartis Ag Process for preparing a solid dispersion of a pharmaceutically active agent that has low water solubility in a solid matrix of a water-soluble polyalkylene glycol as a carrier.
ES2039287T3 (en) * 1987-01-14 1993-09-16 Ciba-Geigy Ag PROCEDURE FOR OBTAINING A PERORAL THERAPEUTIC SYSTEM FOR HARDLY SOLUBLE ACTIVE PRODUCTS.
FR2610827B1 (en) * 1987-02-18 1991-09-13 Pf Medicament DIHYDROERGOTAMINE (D.H.E.) TABLET OF THE HYDROPHILIC MATRIX TYPE AND MANUFACTURING METHOD THEREOF
US5064656A (en) * 1989-11-14 1991-11-12 Dr. Gergely & Co. Uncoated pharmaceutical reaction tablet
DE4401646A1 (en) * 1994-01-21 1995-07-27 Krewel Werke Gmbh Optimally releasing kava extracts
US6524832B1 (en) 1994-02-04 2003-02-25 Arch Development Corporation DNA damaging agents in combination with tyrosine kinase inhibitors
KR100597331B1 (en) * 1997-12-22 2006-07-10 쉐링 코포레이션 Molecular dispersion composition with improved bioavailability
US6632455B2 (en) 1997-12-22 2003-10-14 Schering Corporation Molecular dispersion composition with enhanced bioavailability
US6316462B1 (en) 1999-04-09 2001-11-13 Schering Corporation Methods of inducing cancer cell death and tumor regression
US7771746B2 (en) 1999-12-03 2010-08-10 Polichem Sa Methods for making sustained-release pharmaceutical compositions of ergot alkaloids having improved bioavailability and compositions thereof
HK1048254B (en) * 1999-12-03 2005-06-03 Polichem S.A. Methods for making sustained-release pharmaceutical compositions of ergot alkaloids having improved bioavailability and compositions thereof
US7135436B2 (en) 2003-05-05 2006-11-14 J.F. Daley International, Ltd. Solid algicide, preparation and usage in recirculating water
DE60309356T2 (en) * 2003-06-27 2007-08-30 Bioprogress S.P.A. COMPOSITION, BY COMPRESSING COMPOUND OF AN ACTIVE AGENT WITH AN N-VINYL-2-PYRROLIDONE / VINYL ACETATE COPOLYMERS AVAILABLE
ES3063790T3 (en) 2015-06-09 2026-04-20 Lonza Sales Ag Formulations to achieve rapid dissolution of drug from spray-dried dispersions in capsules
KR102882996B1 (en) * 2025-04-07 2025-11-07 (주)휴마스 The device for measuring fractionated carbon and nitrogen in water using a liquid chromatography and membrane conductivity measuring module and an improved UV oxidation reactor, and a measuring method using the same

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1175430A (en) * 1966-04-07 1969-12-23 Sandoz Ltd Pharmaceutical Compositions containing Ergot Alkaloids

Also Published As

Publication number Publication date
BE847368A (en) 1977-04-15
NL184558C (en) 1989-09-01
ATA767976A (en) 1980-10-15
IL50686A0 (en) 1976-12-31
NZ182341A (en) 1978-09-20
DK454176A (en) 1977-04-18
PT65719B (en) 1978-06-12
SG63082G (en) 1983-09-09
PT65719A (en) 1976-11-01
DE2546577B2 (en) 1981-04-02
NL184558B (en) 1989-04-03
NL7611295A (en) 1977-04-19
SE7611189L (en) 1977-04-18
FR2327764A1 (en) 1977-05-13
PH14513A (en) 1981-08-24
DK146194C (en) 1984-01-02
GR61268B (en) 1978-10-17
HK3183A (en) 1983-01-20
GB1560406A (en) 1980-02-06
HU172533B (en) 1978-09-28
CH643737A5 (en) 1984-06-29
NO763446L (en) 1977-04-19
CS199647B2 (en) 1980-07-31
DK146194B (en) 1983-07-25
IL50686A (en) 1979-05-31
JPS5251014A (en) 1977-04-23
AU508628B2 (en) 1980-03-27
FR2327764B1 (en) 1979-03-02
DE2546577A1 (en) 1977-04-21
CA1079641A (en) 1980-06-17
IE43778B1 (en) 1981-05-20
AT362510B (en) 1981-05-25
JPS5854122B2 (en) 1983-12-02
ZA766166B (en) 1978-05-30
ES452420A1 (en) 1978-04-16
FI762875A7 (en) 1977-04-18
AU1875476A (en) 1978-04-20
NO144468C (en) 1981-09-09
MY8400063A (en) 1984-12-31
SU1165223A3 (en) 1985-06-30
SE430379B (en) 1983-11-14
NO144468B (en) 1981-06-01

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Legal Events

Date Code Title Description
MM4A Patent lapsed