IE43972L - Piperidinoalkylindole derivatives - Google Patents
Piperidinoalkylindole derivativesInfo
- Publication number
- IE43972L IE43972L IE762396A IE239676A IE43972L IE 43972 L IE43972 L IE 43972L IE 762396 A IE762396 A IE 762396A IE 239676 A IE239676 A IE 239676A IE 43972 L IE43972 L IE 43972L
- Authority
- IE
- Ireland
- Prior art keywords
- compounds
- nov
- alkyl
- piperidinoalkylindole
- derivatives
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 abstract 3
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- BREBKAKBNYXIOP-UHFFFAOYSA-N 4-(phenoxymethyl)piperidine Chemical compound C1CNCCC1COC1=CC=CC=C1 BREBKAKBNYXIOP-UHFFFAOYSA-N 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 230000003276 anti-hypertensive effect Effects 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Cardiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Heart & Thoracic Surgery (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
Abstract
1510765 Piperidinoalkylindoles BOEHRINGER MANNHEIM GmbH 4 Nov 1976 [7 Nov 1975] 45918/76 Heading C2C The invention comprises compounds of formula and their pharmacologically compatible salts, wherein R 1 , R 2 and R 3 are each H or C 1-6 alkyl, or R 3 may be halogen or C 1-6 alkoxy, and X is C 2 or C 3 alkylene. In examples, these compounds are prepared by either reacting a 3-bromoalkyl- or toxyloxyalkylindole with a 4-phenoxymethylpiperidine or introducing R 1 = alkyl. Therapeutic compositions having antihypertensive activity comprise compounds of the above formula, and may be administered orally or parenterally.
[GB1510765A]
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19752550001 DE2550001A1 (en) | 1975-11-07 | 1975-11-07 | NEW INDOL DERIVATIVES AND PROCESS FOR THEIR PRODUCTION |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IE43972L true IE43972L (en) | 1977-05-07 |
| IE43972B1 IE43972B1 (en) | 1981-07-15 |
Family
ID=5961169
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IE2396/76A IE43972B1 (en) | 1975-11-07 | 1976-10-29 | Piperidine derivatives of indole |
Country Status (15)
| Country | Link |
|---|---|
| JP (1) | JPS5259164A (en) |
| AT (1) | AT352727B (en) |
| BE (1) | BE847975A (en) |
| CA (1) | CA1077941A (en) |
| DE (1) | DE2550001A1 (en) |
| DK (1) | DK141529C (en) |
| FI (1) | FI763150A7 (en) |
| FR (1) | FR2330396A1 (en) |
| GB (1) | GB1510765A (en) |
| IE (1) | IE43972B1 (en) |
| LU (1) | LU76143A1 (en) |
| NL (1) | NL7612288A (en) |
| SE (1) | SE7612236L (en) |
| SU (1) | SU628816A3 (en) |
| ZA (1) | ZA766379B (en) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2905876A1 (en) | 1979-02-16 | 1980-08-28 | Boehringer Mannheim Gmbh | NEW PIPERIDINOPROPYL DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF AND MEDICINAL PRODUCTS CONTAINING THESE COMPOUNDS |
| US4327103A (en) * | 1980-07-07 | 1982-04-27 | Hoechst-Roussel Pharmaceuticals Incorporated | 3-{3-[4-(4-Fluorobenzoyl)piperidyl]propyl}-2-methyl indole |
-
1975
- 1975-11-07 DE DE19752550001 patent/DE2550001A1/en not_active Withdrawn
-
1976
- 1976-10-25 ZA ZA766379A patent/ZA766379B/en unknown
- 1976-10-28 CA CA264,610A patent/CA1077941A/en not_active Expired
- 1976-10-29 IE IE2396/76A patent/IE43972B1/en unknown
- 1976-11-02 SU SU762415646A patent/SU628816A3/en active
- 1976-11-02 DK DK495076A patent/DK141529C/en active
- 1976-11-03 FI FI763150A patent/FI763150A7/fi not_active Application Discontinuation
- 1976-11-03 SE SE7612236A patent/SE7612236L/en not_active Application Discontinuation
- 1976-11-04 BE BE172070A patent/BE847975A/en unknown
- 1976-11-04 GB GB45918/76A patent/GB1510765A/en not_active Expired
- 1976-11-05 LU LU76143A patent/LU76143A1/xx unknown
- 1976-11-05 AT AT823976A patent/AT352727B/en not_active IP Right Cessation
- 1976-11-05 FR FR7633391A patent/FR2330396A1/en active Granted
- 1976-11-05 JP JP51133141A patent/JPS5259164A/en active Pending
- 1976-11-05 NL NL7612288A patent/NL7612288A/en not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| IE43972B1 (en) | 1981-07-15 |
| BE847975A (en) | 1977-05-04 |
| DE2550001A1 (en) | 1977-05-12 |
| CA1077941A (en) | 1980-05-20 |
| ZA766379B (en) | 1977-10-26 |
| FI763150A7 (en) | 1977-05-08 |
| FR2330396B1 (en) | 1979-06-29 |
| ATA823976A (en) | 1979-03-15 |
| FR2330396A1 (en) | 1977-06-03 |
| AT352727B (en) | 1979-10-10 |
| SU628816A3 (en) | 1978-10-15 |
| DK141529C (en) | 1980-09-01 |
| DK141529B (en) | 1980-04-14 |
| NL7612288A (en) | 1977-05-10 |
| JPS5259164A (en) | 1977-05-16 |
| LU76143A1 (en) | 1977-05-18 |
| SE7612236L (en) | 1977-05-08 |
| GB1510765A (en) | 1978-05-17 |
| DK495076A (en) | 1977-05-08 |
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