IE44428L - Fumarate salt of the antibiotic pleuromutilin. - Google Patents

Fumarate salt of the antibiotic pleuromutilin.

Info

Publication number
IE44428L
IE44428L IE761943A IE194376A IE44428L IE 44428 L IE44428 L IE 44428L IE 761943 A IE761943 A IE 761943A IE 194376 A IE194376 A IE 194376A IE 44428 L IE44428 L IE 44428L
Authority
IE
Ireland
Prior art keywords
fumarate salt
antibiotic
neutral fumarate
plueromutilin
mercaptoacetoxy
Prior art date
Application number
IE761943A
Other versions
IE44428B1 (en
Original Assignee
Squibb & Sons Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US05/709,983 external-priority patent/US4086359A/en
Application filed by Squibb & Sons Inc filed Critical Squibb & Sons Inc
Publication of IE44428L publication Critical patent/IE44428L/en
Publication of IE44428B1 publication Critical patent/IE44428B1/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C57/00Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
    • C07C57/02Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms with only carbon-to-carbon double bonds as unsaturation
    • C07C57/13Dicarboxylic acids
    • C07C57/15Fumaric acid
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K20/00Accessory food factors for animal feeding-stuffs
    • A23K20/10Organic substances
    • A23K20/195Antibiotics
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K50/00Feeding-stuffs specially adapted for particular animals
    • A23K50/30Feeding-stuffs specially adapted for particular animals for swines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Polymers & Plastics (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Food Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Animal Husbandry (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Birds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Fodder In General (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

A new neutral fumarate salt of a derivative of the antibiotic plueromutilin -14-deoxy-14-(2-diethylaminoethyl)-mercaptoacetoxy!mutilin neutral fumarate- has been found whose physical properties made bulk manufacture more reproducible, simplify formulation and provide advantages in the administration of the substance. A new neutral fumarate salt of a derivative of the antibiotic plueromutilin -14-deoxy-14-¢(2-diethylaminoethyl)-mercaptoacetoxy!mutilin neutral fumarate- has been found whose physical properties made bulk manufacture more reproducible, simplify formulation and provide advantages in the administration of the substance. [CA1077056A]
IE1943/76A 1975-09-30 1976-08-31 New derivatives of pleuromutilin and compositions containig same IE44428B1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US61808775A 1975-09-30 1975-09-30
US05/709,983 US4086359A (en) 1975-09-30 1976-07-30 Derivatives of pleuromutilin and compositions

Publications (2)

Publication Number Publication Date
IE44428L true IE44428L (en) 1977-03-30
IE44428B1 IE44428B1 (en) 1981-12-02

Family

ID=27088148

Family Applications (1)

Application Number Title Priority Date Filing Date
IE1943/76A IE44428B1 (en) 1975-09-30 1976-08-31 New derivatives of pleuromutilin and compositions containig same

Country Status (8)

Country Link
JP (1) JPS6029383B2 (en)
AT (1) AT350835B (en)
CA (1) CA1077056A (en)
CH (1) CH595339A5 (en)
DE (1) DE2643672C2 (en)
FR (1) FR2326186A1 (en)
GB (1) GB1547437A (en)
IE (1) IE44428B1 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2526019A1 (en) * 1982-04-28 1983-11-04 Sandoz Sa NOVEL DERIVATIVES OF PLEUROMUTILINE, THEIR PREPARATION AND THEIR USE AS MEDICAMENTS

Also Published As

Publication number Publication date
AT350835B (en) 1979-06-25
CA1077056A (en) 1980-05-06
JPS6029383B2 (en) 1985-07-10
DE2643672C2 (en) 1986-07-24
GB1547437A (en) 1979-06-20
CH595339A5 (en) 1978-02-15
FR2326186B1 (en) 1978-11-17
IE44428B1 (en) 1981-12-02
FR2326186A1 (en) 1977-04-29
ATA722976A (en) 1978-11-15
JPS5244221A (en) 1977-04-07
DE2643672A1 (en) 1977-04-07

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Legal Events

Date Code Title Description
MM4A Patent lapsed