IE45548L - Pyridazinyl thiomethyl cephalosporins. - Google Patents
Pyridazinyl thiomethyl cephalosporins.Info
- Publication number
- IE45548L IE45548L IE771430A IE143077A IE45548L IE 45548 L IE45548 L IE 45548L IE 771430 A IE771430 A IE 771430A IE 143077 A IE143077 A IE 143077A IE 45548 L IE45548 L IE 45548L
- Authority
- IE
- Ireland
- Prior art keywords
- pyridazinyl
- formula
- compounds
- compound
- thiomethyl
- Prior art date
Links
- 229930186147 Cephalosporin Natural products 0.000 title 1
- -1 Pyridazinyl thiomethyl cephalosporins Chemical class 0.000 title 1
- 229940124587 cephalosporin Drugs 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 5
- 241000606790 Haemophilus Species 0.000 abstract 1
- 206010061190 Haemophilus infection Diseases 0.000 abstract 1
- 206010062212 Neisseria infection Diseases 0.000 abstract 1
- 230000000844 anti-bacterial effect Effects 0.000 abstract 1
- 208000010899 haemophilus infectious disease Diseases 0.000 abstract 1
- 239000000825 pharmaceutical preparation Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D307/38—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D307/54—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D307/56—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
- C07D317/10—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings
- C07D317/32—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D317/34—Oxygen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Communicable Diseases (AREA)
- Pharmacology & Pharmacy (AREA)
- Oncology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Cephalosporin Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Abstract
Compounds of the formula I are prepared by reaction of a compound of the formula V with the compound of the formula VI. The meaning of the substituents A and A<1> can be taken from Claim 1. The compounds prepared can be used as active compounds in pharmaceutical preparations having antibacterial action. They are used e.g. for the control of Shig. dysenteriae, Sal. enteritidis, Haemophilus and Neisseria infections. <IMAGE>
[GB1561236A]
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US70522676A | 1976-07-13 | 1976-07-13 | |
| US05/771,859 US4103085A (en) | 1977-02-24 | 1977-02-24 | 7-(Syn-α-alkoxy-iminofurylacetamido-3-(2-carboxyalkyl-2,3-dihydro-s-triazolo[4,3-b]pyridazin-3-on-6-ylthiomethyl)-3-cephem-4-carboxylic acids |
| US05/777,986 US4112228A (en) | 1976-07-13 | 1977-03-16 | 7-(D-α-Hydroxy-2-arylacetamido)-3-(2-carboxyalkyl-2,3-dihydro-s-triazolo-[4,3-b]pyridazin-3-on-6-ylthiomethyl)-3-cephem-4-carboxylic acids and derivatives |
| US05/788,056 US4104469A (en) | 1977-04-15 | 1977-04-15 | 7-(Syn-α-alkoxy-iminofuryl)acetamido-3-(2-methyl-2,3-dihydro-s-triazolo[4,3-b]pyridazin-3-on-6-ylthiomethyl)-3-cephem-4-carboxylic acids |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IE45548L true IE45548L (en) | 1978-01-13 |
| IE45548B1 IE45548B1 (en) | 1982-09-22 |
Family
ID=27505490
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IE1430/77A IE45548B1 (en) | 1976-07-13 | 1977-07-11 | Cephalosporins |
Country Status (16)
| Country | Link |
|---|---|
| JP (1) | JPS5328191A (en) |
| AU (1) | AU511805B2 (en) |
| BE (1) | BE856785A (en) |
| CA (1) | CA1142918A (en) |
| CH (1) | CH640239A5 (en) |
| DE (1) | DE2731724A1 (en) |
| DK (1) | DK143344C (en) |
| FI (1) | FI772179A7 (en) |
| FR (1) | FR2358411A1 (en) |
| GB (1) | GB1561236A (en) |
| GR (1) | GR81280B (en) |
| IE (1) | IE45548B1 (en) |
| LU (1) | LU77756A1 (en) |
| NL (1) | NL7707820A (en) |
| SE (2) | SE7708053L (en) |
| YU (1) | YU171977A (en) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0228061A3 (en) * | 1985-12-23 | 1988-12-14 | Takeda Chemical Industries, Ltd. | Cephem compounds |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3946000A (en) * | 1973-10-31 | 1976-03-23 | Bristol-Myers Company | 7-[α-(2-Aminomethyl-1-cyclohexenyl)-acetamido]-3-heterocyclic thiomethyl-3-cephem-4-carboxylic acids |
-
1977
- 1977-07-11 DK DK312677A patent/DK143344C/en not_active IP Right Cessation
- 1977-07-11 SE SE7708053A patent/SE7708053L/en not_active Application Discontinuation
- 1977-07-11 IE IE1430/77A patent/IE45548B1/en unknown
- 1977-07-11 YU YU01719/77A patent/YU171977A/en unknown
- 1977-07-12 CA CA000282573A patent/CA1142918A/en not_active Expired
- 1977-07-12 GB GB29212/77A patent/GB1561236A/en not_active Expired
- 1977-07-13 LU LU77756A patent/LU77756A1/xx unknown
- 1977-07-13 JP JP8301677A patent/JPS5328191A/en active Pending
- 1977-07-13 CH CH868077A patent/CH640239A5/en not_active IP Right Cessation
- 1977-07-13 DE DE19772731724 patent/DE2731724A1/en not_active Withdrawn
- 1977-07-13 BE BE179319A patent/BE856785A/en not_active IP Right Cessation
- 1977-07-13 FR FR7721814A patent/FR2358411A1/en active Granted
- 1977-07-13 GR GR53959A patent/GR81280B/el unknown
- 1977-07-13 NL NL7707820A patent/NL7707820A/en not_active Application Discontinuation
- 1977-07-13 FI FI772179A patent/FI772179A7/fi not_active Application Discontinuation
- 1977-07-13 AU AU26982/77A patent/AU511805B2/en not_active Expired
-
1982
- 1982-09-24 SE SE8205482A patent/SE8205482D0/en not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| FR2358411A1 (en) | 1978-02-10 |
| AU2698277A (en) | 1979-01-18 |
| FR2358411B1 (en) | 1981-06-12 |
| DK143344C (en) | 1981-12-14 |
| SE8205482L (en) | 1982-09-24 |
| SE8205482D0 (en) | 1982-09-24 |
| DK312677A (en) | 1978-01-14 |
| NL7707820A (en) | 1978-01-17 |
| IE45548B1 (en) | 1982-09-22 |
| JPS5328191A (en) | 1978-03-16 |
| LU77756A1 (en) | 1978-02-08 |
| YU171977A (en) | 1982-06-30 |
| GR81280B (en) | 1984-12-11 |
| AU511805B2 (en) | 1980-09-04 |
| SE7708053L (en) | 1978-01-14 |
| BE856785A (en) | 1978-01-13 |
| CA1142918A (en) | 1983-03-15 |
| CH640239A5 (en) | 1983-12-30 |
| DE2731724A1 (en) | 1978-01-19 |
| GB1561236A (en) | 1980-02-13 |
| FI772179A7 (en) | 1978-01-14 |
| DK143344B (en) | 1981-08-10 |
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