IE45771L - Benzocycloheptenes - Google Patents

Benzocycloheptenes

Info

Publication number
IE45771L
IE45771L IE771882A IE188277A IE45771L IE 45771 L IE45771 L IE 45771L IE 771882 A IE771882 A IE 771882A IE 188277 A IE188277 A IE 188277A IE 45771 L IE45771 L IE 45771L
Authority
IE
Ireland
Prior art keywords
alkyl
alkoxy
hydrogen
cycloalkyl
benzocycloheptenes
Prior art date
Application number
IE771882A
Other versions
IE45771B1 (en
Original Assignee
Sandoz Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from CH632177A external-priority patent/CH628870A5/en
Priority claimed from CH632077A external-priority patent/CH635310A5/en
Application filed by Sandoz Ltd filed Critical Sandoz Ltd
Publication of IE45771L publication Critical patent/IE45771L/en
Publication of IE45771B1 publication Critical patent/IE45771B1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
    • C07D333/14—Radicals substituted by singly bound hetero atoms other than halogen
    • C07D333/20—Radicals substituted by singly bound hetero atoms other than halogen by nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/02—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements
    • C07D295/027—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements containing only one hetero ring
    • C07D295/033—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements containing only one hetero ring with the ring nitrogen atoms directly attached to carbocyclic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/06—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by halogen atoms or nitro radicals
    • C07D295/073—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by halogen atoms or nitro radicals with the ring nitrogen atoms and the substituents separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Psychiatry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)

Abstract

The invention provides compounds of formula wherein R1 is hydrogen, alkyl, alkoxy or halogen, R2 is hydrogen or, when R1 is alkoxy, also alkoxy, or R1 and R2 when bonded to adjacent carbon atoms are methylenedioxy, R3 is hydrogen or alkyl, R4 may, for example, be alkyl, cycloalkyl alkyl of cycloalkyl, or R3 and R4 together with the nitrogen atom to which they are bound may be pyrrolidine, and Z may, for example, be substituted or unsub stituted phenyl, which posses pharmacological, e.g. psychostimulant, activity. [CA1091231A]
IE1882/77A 1977-05-23 1977-09-12 Tetrahydrobenzocycloheptenes IE45771B1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH632177A CH628870A5 (en) 1977-05-23 1977-05-23 Process for the preparation of benzocycloheptene derivatives
CH632077A CH635310A5 (en) 1977-05-23 1977-05-23 Process for preparing novel benzocycloheptene derivatives

Publications (2)

Publication Number Publication Date
IE45771L true IE45771L (en) 1978-11-23
IE45771B1 IE45771B1 (en) 1982-11-17

Family

ID=25699361

Family Applications (1)

Application Number Title Priority Date Filing Date
IE1882/77A IE45771B1 (en) 1977-05-23 1977-09-12 Tetrahydrobenzocycloheptenes

Country Status (17)

Country Link
JP (1) JPS53144560A (en)
AU (1) AU517587B2 (en)
CA (1) CA1091231A (en)
DE (1) DE2740857A1 (en)
DK (1) DK390477A (en)
ES (1) ES462647A1 (en)
FI (1) FI772729A7 (en)
FR (1) FR2391992A1 (en)
GB (1) GB1589776A (en)
IE (1) IE45771B1 (en)
IL (1) IL52929A (en)
NL (1) NL7710247A (en)
NZ (1) NZ185162A (en)
PH (1) PH17683A (en)
PT (1) PT67052B (en)
SE (1) SE7710009L (en)
SU (1) SU856378A3 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2931986B2 (en) * 1989-02-17 1999-08-09 武田薬品工業株式会社 Aralkylamine derivatives

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2319332A1 (en) * 1975-07-28 1977-02-25 Roussel Uclaf NEW DERIVATIVES OF AMINOBENZOCYCLOHEPTENE AND THEIR SALTS, METHOD OF PREPARATION AND APPLICATION AS MEDICINAL PRODUCTS OF THE SAID PRODUCTS

Also Published As

Publication number Publication date
PT67052B (en) 1979-05-14
SE7710009L (en) 1978-11-24
DK390477A (en) 1978-11-24
IL52929A0 (en) 1977-11-30
GB1589776A (en) 1981-05-20
IE45771B1 (en) 1982-11-17
NZ185162A (en) 1980-03-05
ES462647A1 (en) 1978-12-16
PT67052A (en) 1977-10-01
IL52929A (en) 1981-06-29
AU517587B2 (en) 1981-08-13
DE2740857A1 (en) 1978-12-07
PH17683A (en) 1984-11-02
FR2391992A1 (en) 1978-12-22
NL7710247A (en) 1978-11-27
JPS53144560A (en) 1978-12-15
CA1091231A (en) 1980-12-09
FR2391992B1 (en) 1981-02-06
SU856378A3 (en) 1981-08-15
FI772729A7 (en) 1978-11-24
AU2883177A (en) 1979-03-22

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