IE45938L - 1-phenoxy-3-amino-propan-2-ols - Google Patents
1-phenoxy-3-amino-propan-2-olsInfo
- Publication number
- IE45938L IE45938L IE772046A IE204677A IE45938L IE 45938 L IE45938 L IE 45938L IE 772046 A IE772046 A IE 772046A IE 204677 A IE204677 A IE 204677A IE 45938 L IE45938 L IE 45938L
- Authority
- IE
- Ireland
- Prior art keywords
- ols
- propan
- phenoxy
- compounds
- amino
- Prior art date
Links
- JZEHWMUIAKALDN-UHFFFAOYSA-N 1-amino-3-phenoxypropan-2-ol Chemical class NCC(O)COC1=CC=CC=C1 JZEHWMUIAKALDN-UHFFFAOYSA-N 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 3
- 150000001412 amines Chemical class 0.000 abstract 1
- 102000012740 beta Adrenergic Receptors Human genes 0.000 abstract 1
- 108010079452 beta Adrenergic Receptors Proteins 0.000 abstract 1
- 238000006243 chemical reaction Methods 0.000 abstract 1
- 125000003700 epoxy group Chemical group 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 150000003141 primary amines Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D207/32—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C07D207/325—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms with substituted hydrocarbon radicals directly attached to the ring nitrogen atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C255/00—Carboxylic acid nitriles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
- C07D295/096—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Epoxy Compounds (AREA)
- Pyrrole Compounds (AREA)
Abstract
The process is used for preparing the novel amines of the formula (I) <IMAGE> R<1>, R<2> and R<3> are defined in Patent Claim 1. The reactions for preparing the said compounds always take place between primary amines and compounds having a reactive, esterified hydroxyl group or an epoxy group. The novel compounds effectively block beta receptors.
[SE7611125A]
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE7611125A SE416545B (en) | 1976-10-07 | 1976-10-07 | PROCEDURE FOR THE PREPARATION OF NEW HEART-ACTIVE 1-FRNOXI-3-AMINOPROPAN-2-OL-DERIVATIVES |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IE45938L true IE45938L (en) | 1978-04-07 |
| IE45938B1 IE45938B1 (en) | 1983-01-12 |
Family
ID=20329066
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IE2046/77A IE45938B1 (en) | 1976-10-07 | 1977-10-06 | 1-phenoxy-3-amino-propan-2-ols |
Country Status (22)
| Country | Link |
|---|---|
| JP (1) | JPS5346928A (en) |
| AT (1) | AT351509B (en) |
| AU (1) | AU516727B2 (en) |
| BE (1) | BE859474A (en) |
| CA (1) | CA1093096A (en) |
| CH (1) | CH636337A5 (en) |
| CS (5) | CS208731B2 (en) |
| DD (1) | DD132195A5 (en) |
| DE (1) | DE2743493A1 (en) |
| DK (1) | DK145375C (en) |
| FI (1) | FI772936A7 (en) |
| FR (1) | FR2367054A1 (en) |
| GB (1) | GB1589838A (en) |
| HU (1) | HU177638B (en) |
| IE (1) | IE45938B1 (en) |
| LU (1) | LU78263A1 (en) |
| NL (1) | NL7710941A (en) |
| NO (1) | NO145436C (en) |
| NZ (1) | NZ185318A (en) |
| SE (1) | SE416545B (en) |
| SU (3) | SU735166A3 (en) |
| ZA (1) | ZA775603B (en) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DD150456A5 (en) * | 1979-03-01 | 1981-09-02 | Ciba Geigy Ag | PROCESS FOR THE PREPARATION OF DERIVATIVES OF 3-AMINO-1,2-PROPANDIOL |
| GB8519154D0 (en) * | 1985-07-30 | 1985-09-04 | Ici Plc | Aromatic ethers |
| JPH0627370B2 (en) * | 1985-08-23 | 1994-04-13 | 日本エステル株式会社 | Polyester irregular cross-section thick and thin yarn |
| GB8925032D0 (en) * | 1989-11-06 | 1989-12-28 | Ici Plc | Chemical compounds |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BE590054A (en) * | 1959-04-22 | 1960-10-24 | Pfizer | Alkylamines and their preparation. |
| GB1264128A (en) * | 1968-06-29 | 1972-02-16 | ||
| GB1433920A (en) * | 1973-10-01 | 1976-04-28 | Ici Ltd | Alkanolamine derivatives |
-
1976
- 1976-10-07 SE SE7611125A patent/SE416545B/en unknown
-
1977
- 1977-09-19 ZA ZA00775603A patent/ZA775603B/en unknown
- 1977-09-28 DE DE19772743493 patent/DE2743493A1/en not_active Withdrawn
- 1977-10-03 NZ NZ185318A patent/NZ185318A/en unknown
- 1977-10-03 AT AT702177A patent/AT351509B/en not_active IP Right Cessation
- 1977-10-04 AU AU29300/77A patent/AU516727B2/en not_active Expired
- 1977-10-05 HU HU77HE752A patent/HU177638B/en unknown
- 1977-10-05 DD DD7700201371A patent/DD132195A5/en unknown
- 1977-10-05 FI FI772936A patent/FI772936A7/en not_active Application Discontinuation
- 1977-10-05 NL NL7710941A patent/NL7710941A/en not_active Application Discontinuation
- 1977-10-06 CS CS776486A patent/CS208731B2/en unknown
- 1977-10-06 FR FR7730156A patent/FR2367054A1/en active Granted
- 1977-10-06 DK DK443177A patent/DK145375C/en active
- 1977-10-06 CA CA288,290A patent/CA1093096A/en not_active Expired
- 1977-10-06 IE IE2046/77A patent/IE45938B1/en unknown
- 1977-10-06 CS CS776486A patent/CS208734B2/en unknown
- 1977-10-06 CS CS776486A patent/CS208733B2/en unknown
- 1977-10-06 LU LU78263A patent/LU78263A1/xx unknown
- 1977-10-06 CS CS776486A patent/CS208730B2/en unknown
- 1977-10-06 CS CS776486A patent/CS208732B2/en unknown
- 1977-10-06 NO NO773406A patent/NO145436C/en unknown
- 1977-10-06 GB GB41699/77A patent/GB1589838A/en not_active Expired
- 1977-10-06 SU SU772528198A patent/SU735166A3/en active
- 1977-10-07 BE BE181531A patent/BE859474A/en unknown
- 1977-10-07 CH CH1230577A patent/CH636337A5/en not_active IP Right Cessation
- 1977-10-07 JP JP12133477A patent/JPS5346928A/en active Pending
-
1978
- 1978-07-28 SU SU782641105A patent/SU959623A3/en active
- 1978-07-28 SU SU782640402A patent/SU784760A3/en active
Also Published As
| Publication number | Publication date |
|---|---|
| CS208734B2 (en) | 1981-09-15 |
| CS208732B2 (en) | 1981-09-15 |
| ZA775603B (en) | 1978-06-28 |
| SE416545B (en) | 1981-01-19 |
| DK145375C (en) | 1983-04-11 |
| HU177638B (en) | 1981-11-28 |
| JPS5346928A (en) | 1978-04-27 |
| NO145436B (en) | 1981-12-14 |
| BE859474A (en) | 1978-04-07 |
| DD132195A5 (en) | 1978-09-06 |
| AU516727B2 (en) | 1981-06-18 |
| NZ185318A (en) | 1980-02-21 |
| DK443177A (en) | 1978-04-08 |
| LU78263A1 (en) | 1978-06-09 |
| FR2367054B1 (en) | 1981-11-06 |
| CS208730B2 (en) | 1981-09-15 |
| GB1589838A (en) | 1981-05-20 |
| CS208731B2 (en) | 1981-09-15 |
| SU784760A3 (en) | 1980-11-30 |
| FI772936A7 (en) | 1978-04-08 |
| NL7710941A (en) | 1978-04-11 |
| NO145436C (en) | 1982-03-24 |
| SE7611125L (en) | 1978-04-08 |
| DE2743493A1 (en) | 1978-04-13 |
| CA1093096A (en) | 1981-01-06 |
| NO773406L (en) | 1978-04-10 |
| DK145375B (en) | 1982-11-08 |
| AU2930077A (en) | 1979-04-12 |
| CH636337A5 (en) | 1983-05-31 |
| SU735166A3 (en) | 1980-05-15 |
| ATA702177A (en) | 1979-01-15 |
| CS208733B2 (en) | 1981-09-15 |
| IE45938B1 (en) | 1983-01-12 |
| AT351509B (en) | 1979-07-25 |
| FR2367054A1 (en) | 1978-05-05 |
| SU959623A3 (en) | 1982-09-15 |
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