IE45967L - Phenoxyacetic acid derivatives - Google Patents
Phenoxyacetic acid derivativesInfo
- Publication number
- IE45967L IE45967L IE771933A IE193377A IE45967L IE 45967 L IE45967 L IE 45967L IE 771933 A IE771933 A IE 771933A IE 193377 A IE193377 A IE 193377A IE 45967 L IE45967 L IE 45967L
- Authority
- IE
- Ireland
- Prior art keywords
- phenoxyacetic acid
- acid derivatives
- dichloro
- acid
- phenoxyacetic
- Prior art date
Links
- LCPDWSOZIOUXRV-UHFFFAOYSA-N phenoxyacetic acid Chemical class OC(=O)COC1=CC=CC=C1 LCPDWSOZIOUXRV-UHFFFAOYSA-N 0.000 title 1
- YTPLMLYBLZKORZ-UHFFFAOYSA-N Thiophene Chemical compound C=1C=CSC=1 YTPLMLYBLZKORZ-UHFFFAOYSA-N 0.000 abstract 2
- RHNDEZPJQWPQJU-UHFFFAOYSA-N 4-(carboxymethoxy)-2,3-dichlorobenzoic acid Chemical compound OC(=O)COC1=CC=C(C(O)=O)C(Cl)=C1Cl RHNDEZPJQWPQJU-UHFFFAOYSA-N 0.000 abstract 1
- 208000004880 Polyuria Diseases 0.000 abstract 1
- 125000005907 alkyl ester group Chemical group 0.000 abstract 1
- 230000001882 diuretic effect Effects 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 150000002148 esters Chemical class 0.000 abstract 1
- 229930192474 thiophene Natural products 0.000 abstract 1
- AGHANLSBXUWXTB-UHFFFAOYSA-N tienilic acid Chemical compound ClC1=C(Cl)C(OCC(=O)O)=CC=C1C(=O)C1=CC=CS1 AGHANLSBXUWXTB-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D333/38—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D333/40—Thiophene-2-carboxylic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/10—Antioedematous agents; Diuretics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/45—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by condensation
- C07C45/46—Friedel-Crafts reactions
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
- C07C49/76—Ketones containing a keto group bound to a six-membered aromatic ring
- C07C49/84—Ketones containing a keto group bound to a six-membered aromatic ring containing ether groups, groups, groups, or groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/06—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom containing only hydrogen and carbon atoms in addition to the ring nitrogen atom
- C07D213/16—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom containing only hydrogen and carbon atoms in addition to the ring nitrogen atom containing only one pyridine ring
- C07D213/20—Quaternary compounds thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
- C07D333/22—Radicals substituted by doubly bound hetero atoms, or by two hetero atoms other than halogen singly bound to the same carbon atom
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- General Chemical & Material Sciences (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Heterocyclic Compounds Containing Sulfur Atoms (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Abstract
2,3-Dichloro-4-(2-thenoyl)phenoxyacetic acid is a drug possessing a diuretic effect. It is prepared by acylating thiophene with 2,3-dichloro-4-carboxyphenoxyacetic acid or its alkyl ester. In the latter case, the resulting ester is hydrolysed.
[GB1568319A]
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR7628274A FR2364916A1 (en) | 1976-09-21 | 1976-09-21 | PROCESS FOR OBTAINING DICHLORO-2,3 (THENOYL-2) -4 PHENOXYACETIC ACID |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IE45967L true IE45967L (en) | 1978-03-21 |
| IE45967B1 IE45967B1 (en) | 1983-01-12 |
Family
ID=9177881
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IE1933/77A IE45967B1 (en) | 1976-09-21 | 1977-09-21 | Phenoxyacetic acid derivatives |
Country Status (21)
| Country | Link |
|---|---|
| JP (1) | JPS5340758A (en) |
| BE (1) | BE858848A (en) |
| CA (1) | CA1092132A (en) |
| CH (1) | CH632754A5 (en) |
| CS (1) | CS194693B2 (en) |
| DD (1) | DD132870A5 (en) |
| DE (1) | DE2742126A1 (en) |
| ES (1) | ES462472A1 (en) |
| FR (1) | FR2364916A1 (en) |
| GB (2) | GB1568319A (en) |
| GR (1) | GR63570B (en) |
| HU (1) | HU172875B (en) |
| IE (1) | IE45967B1 (en) |
| IL (1) | IL52881A (en) |
| IT (1) | IT1086083B (en) |
| NL (1) | NL7710353A (en) |
| PL (1) | PL200937A1 (en) |
| PT (1) | PT67035B (en) |
| RO (1) | RO72173A (en) |
| SU (1) | SU736871A3 (en) |
| YU (1) | YU222077A (en) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2916980C2 (en) * | 1979-04-26 | 1981-06-19 | Ludwig Heumann & Co GmbH, 8500 Nürnberg | Process for the preparation of thenoyl-phenoxyacetic acid esters |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2458520A (en) * | 1945-11-08 | 1949-01-11 | Socony Vacuum Oil Co Inc | Acylation of thiophene |
-
1976
- 1976-09-21 FR FR7628274A patent/FR2364916A1/en active Granted
-
1977
- 1977-09-01 CA CA286,003A patent/CA1092132A/en not_active Expired
- 1977-09-02 IL IL52881A patent/IL52881A/en unknown
- 1977-09-07 IT IT27349/77A patent/IT1086083B/en active
- 1977-09-14 GB GB38258/77A patent/GB1568319A/en not_active Expired
- 1977-09-14 GB GB20299/79A patent/GB1568320A/en not_active Expired
- 1977-09-14 CS CS775985A patent/CS194693B2/en unknown
- 1977-09-15 PT PT67035A patent/PT67035B/en unknown
- 1977-09-17 RO RO7791606A patent/RO72173A/en unknown
- 1977-09-19 GR GR54374A patent/GR63570B/en unknown
- 1977-09-19 DE DE19772742126 patent/DE2742126A1/en not_active Withdrawn
- 1977-09-19 BE BE181030A patent/BE858848A/en not_active IP Right Cessation
- 1977-09-19 PL PL20093777A patent/PL200937A1/en unknown
- 1977-09-20 YU YU02220/77A patent/YU222077A/en unknown
- 1977-09-20 HU HU77RO00000945A patent/HU172875B/en unknown
- 1977-09-20 ES ES462472A patent/ES462472A1/en not_active Expired
- 1977-09-20 CH CH1151177A patent/CH632754A5/en not_active IP Right Cessation
- 1977-09-20 DD DD7700201120A patent/DD132870A5/en unknown
- 1977-09-20 JP JP11390077A patent/JPS5340758A/en active Pending
- 1977-09-21 NL NL7710353A patent/NL7710353A/en not_active Application Discontinuation
- 1977-09-21 IE IE1933/77A patent/IE45967B1/en unknown
- 1977-09-21 SU SU772524498A patent/SU736871A3/en active
Also Published As
| Publication number | Publication date |
|---|---|
| GB1568320A (en) | 1980-05-29 |
| PT67035A (en) | 1977-10-01 |
| ES462472A1 (en) | 1978-07-16 |
| PL200937A1 (en) | 1978-05-22 |
| FR2364916B1 (en) | 1979-08-17 |
| SU736871A3 (en) | 1980-05-25 |
| CA1092132A (en) | 1980-12-23 |
| CS194693B2 (en) | 1979-12-31 |
| PT67035B (en) | 1979-02-15 |
| FR2364916A1 (en) | 1978-04-14 |
| IE45967B1 (en) | 1983-01-12 |
| JPS5340758A (en) | 1978-04-13 |
| GR63570B (en) | 1979-11-20 |
| CH632754A5 (en) | 1982-10-29 |
| DE2742126A1 (en) | 1978-08-03 |
| RO72173A (en) | 1981-06-26 |
| DD132870A5 (en) | 1978-11-15 |
| HU172875B (en) | 1978-12-28 |
| BE858848A (en) | 1978-03-20 |
| IL52881A0 (en) | 1977-11-30 |
| YU222077A (en) | 1983-02-28 |
| NL7710353A (en) | 1978-03-23 |
| IL52881A (en) | 1981-05-20 |
| IT1086083B (en) | 1985-05-28 |
| GB1568319A (en) | 1980-05-29 |
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