IE771403L - Injection solutions - Google Patents

Injection solutions

Info

Publication number
IE771403L
IE771403L IE771403A IE140377A IE771403L IE 771403 L IE771403 L IE 771403L IE 771403 A IE771403 A IE 771403A IE 140377 A IE140377 A IE 140377A IE 771403 L IE771403 L IE 771403L
Authority
IE
Ireland
Prior art keywords
injection solutions
us4158707a
lipoid
isotonic
preserve
Prior art date
Application number
IE771403A
Other versions
IE46037B1 (en
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from AT511176A external-priority patent/AT352881B/en
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of IE771403L publication Critical patent/IE771403L/en
Publication of IE46037B1 publication Critical patent/IE46037B1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Dispersion Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biophysics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Molecular Biology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Aqueous vehicles for insoluble or sparingly soluble medicaments suitable for parenteral administration are disclosed. The subject vehicles contain, in addition to pharmaceutical adjunct materials to render them isotonic, preserve them and the like, a micelle forming agent comprising cholic acid or a derivative thereof in combination with a lipoid. [US4158707A]
IE1403/77A 1976-07-12 1977-07-06 Injection solutions containing micelle-forming agents IE46037B1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
AT511176A AT352881B (en) 1976-07-12 1976-07-12 METHOD FOR PRODUCING INJECTION SOLUTIONS
CH699477A CH628811A5 (en) 1976-07-12 1977-06-07 Injection solutions

Publications (2)

Publication Number Publication Date
IE771403L true IE771403L (en) 1978-01-12
IE46037B1 IE46037B1 (en) 1983-02-09

Family

ID=25601846

Family Applications (1)

Application Number Title Priority Date Filing Date
IE1403/77A IE46037B1 (en) 1976-07-12 1977-07-06 Injection solutions containing micelle-forming agents

Country Status (18)

Country Link
US (1) US4158707A (en)
JP (1) JPS6051448B2 (en)
AU (1) AU517249B2 (en)
CA (1) CA1082596A (en)
DE (1) DE2730570A1 (en)
DK (1) DK149483C (en)
FR (2) FR2358161A1 (en)
GB (1) GB1587076A (en)
HK (1) HK26584A (en)
IE (1) IE46037B1 (en)
IL (1) IL52458A (en)
IT (1) IT1202370B (en)
LU (2) LU77708A1 (en)
MY (1) MY8500263A (en)
NL (1) NL189072C (en)
NZ (1) NZ184564A (en)
PH (1) PH16333A (en)
SE (1) SE448516B (en)

Families Citing this family (58)

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DE2914788A1 (en) * 1979-04-11 1980-10-16 Nattermann A & Cie PARENTERAL APPLICABLE, STABLE DRUG SOLUTIONS WITH ANTI-INFLAMMATORY EFFECT
CA1173360A (en) * 1979-06-22 1984-08-28 Jurg Schrank Pharmaceutical preparations
US4264583A (en) * 1979-07-25 1981-04-28 The Procter & Gamble Company Gallstone dissolution compositions and method
JPS57163313A (en) * 1981-03-31 1982-10-07 Nippon Shinyaku Co Ltd Vitamin e pharmaceutical and its preparation
JPH0768117B2 (en) * 1983-05-06 1995-07-26 ベスター・インコーポレイテツド Vesicle formulation for controlled drug release
US4649155A (en) * 1983-07-22 1987-03-10 Hoffmann-La Roche Inc. Injectable solutions
JPH0818989B2 (en) * 1984-01-12 1996-02-28 株式会社ミドリ十字 A method for stabilizing prostaglandins in fat emulsions.
CA1264162A (en) * 1984-03-15 1990-01-02 Manfred Breuninger Glycerol ether phosphatides
US5002936A (en) * 1985-04-12 1991-03-26 Seymour Lieberman Lipophilic complexes of pharmacologically active inorganic mineral acid esters of organic compounds
US4831018A (en) * 1985-05-17 1989-05-16 Smithkline Beckman Corporation Polyene antibiotic emulsion formulation
AT388499B (en) * 1985-08-02 1989-06-26 Merz & Co Gmbh & Co METHOD FOR PRODUCING AN ANTIVIRAL AND ANTITUMOR COMPOSITION, AND THE USE THEREOF
US5023271A (en) * 1985-08-13 1991-06-11 California Biotechnology Inc. Pharmaceutical microemulsions
SE8505047L (en) * 1985-10-25 1987-04-26 Nutritional Int Res Inst fat emulsion
CA1319886C (en) 1987-02-03 1993-07-06 Alberto Ferro Mixed micelle solutions
DE3903753A1 (en) * 1989-02-06 1990-08-23 Schering Ag METHOD FOR PRODUCING AQUEOUS MIXED MICRO SOLUTIONS
NZ232865A (en) * 1989-03-21 1992-07-28 Hoffmann La Roche A mixed-micelle solution comprising a micelle former and an immunomodulator
US5085864A (en) * 1989-10-30 1992-02-04 Abbott Laboratories Injectable formulation for lipophilic drugs
DE3938030A1 (en) * 1989-11-13 1991-05-16 Schering Ag METHOD FOR PRODUCING WAITER MIXING MEASUREMENTS
CA2033725C (en) * 1990-01-24 2001-05-29 Folker Pittrof Pharmaceutical and cosmetic compositions containing a salt of cholanic acid
CA2033714A1 (en) * 1990-01-25 1991-07-26 Alberto Ferro Pharmaceutical preparations
FR2663224B1 (en) * 1990-06-14 1995-01-20 Applicationes Farmaceuticas Sa PARENTERAL GALENIC FORM.
DE4122661C2 (en) * 1990-08-06 1996-07-11 Nattermann A & Cie Pharmaceutical product for the treatment of Pneumocystis carinii pneumonia
ZA916314B (en) * 1990-08-17 1992-05-27 Hoffmann La Roche Use of mixed micelles
CA2444071C (en) * 1991-02-08 2008-10-07 Wellstat Therapeutics Corporation Oxypurine nucleosides and their congeners, and acyl derivatives thereof, for improvement of hematopoiesis
DE4336434A1 (en) * 1993-10-26 1995-04-27 Hoechst Ag Pharmaceutical preparation for the parenteral, enteral and dermal administration of practically insoluble drugs and processes for their preparation
EP0682943B1 (en) * 1994-05-20 2003-08-20 GESELLSCHAFT FÜR MEDIZINISCHE FORSCHUNG UND WEITERBILDUNG e.V. GMF Oil-in-water emulsion containing lormetazepam
GB9426104D0 (en) * 1994-12-23 1995-02-22 Merck Sharp & Dohme Use of surfactants and emulsions
JP2740153B2 (en) * 1995-03-07 1998-04-15 エフ・ホフマン−ラ ロシユ アーゲー Mixed micelle
US5759445A (en) * 1995-05-24 1998-06-02 Matsushita Electric Industrial Co., Ltd. Lipid-dispersed solution and process for producing the same
GB2326337A (en) * 1997-06-20 1998-12-23 Phares Pharma Holland Homogeneous lipid compositions for drug delivery
US6350738B1 (en) 1998-03-06 2002-02-26 Brigham Young University Steroid derived antibiotics
US6767904B2 (en) * 1998-03-06 2004-07-27 Bringham Young University Steroid derived antibiotics
ATE440593T1 (en) * 2001-03-27 2009-09-15 Phares Pharm Res Nv METHOD AND COMPOSITION FOR SOLUBILIZING A BIOLOGICALLY ACTIVE COMPOUND WITH LOW WATER SOLUBILITY
EP1730516A1 (en) * 2004-03-30 2006-12-13 Pfizer Products Incorporated Method and device for evaluation of pharmaceutical compositions
US7754230B2 (en) * 2004-05-19 2010-07-13 The Regents Of The University Of California Methods and related compositions for reduction of fat
US20060127468A1 (en) 2004-05-19 2006-06-15 Kolodney Michael S Methods and related compositions for reduction of fat and skin tightening
MXPA06013437A (en) * 2004-05-19 2007-03-23 Los Angeles Biomed Res Inst Use of a detergent for the non-surgical removal of fat.
WO2008065502A1 (en) * 2006-11-29 2008-06-05 Pfizer Products Inc. Pharmaceutical compositions based on a) nanoparticles comprising enteric polymers and b) casein
WO2008125940A2 (en) * 2007-04-17 2008-10-23 Pfizer Products Inc. Nanoparticles comprising non-crystalline drug
US8703204B2 (en) * 2007-05-03 2014-04-22 Bend Research, Inc. Nanoparticles comprising a cholesteryl ester transfer protein inhibitor and anon-ionizable polymer
US8309129B2 (en) * 2007-05-03 2012-11-13 Bend Research, Inc. Nanoparticles comprising a drug, ethylcellulose, and a bile salt
WO2008135852A2 (en) * 2007-05-03 2008-11-13 Pfizer Products Inc. Pharmaceutical compositions comprising nanoparticles and casein
EP2162120B1 (en) * 2007-06-04 2016-05-04 Bend Research, Inc Nanoparticles comprising a non-ionizable cellulosic polymer and an amphiphilic non-ionizable block copolymer
WO2008149230A2 (en) 2007-06-04 2008-12-11 Pfizer Products Inc. Nanoparticles comprising drug, a non-ionizable cellulosic polymer and tocopheryl polyethylene glycol succinate
US20100215747A1 (en) * 2007-07-13 2010-08-26 Corey Jay Bloom Nanoparticles comprising ionizable, poorly water soluble cellulosic polymers
WO2009073216A1 (en) * 2007-12-06 2009-06-11 Bend Research, Inc. Nanoparticles comprising a non-ionizable polymer and an amine-functionalized methacrylate copolymer
EP2231169B1 (en) * 2007-12-06 2016-05-04 Bend Research, Inc. Pharmaceutical compositions comprising nanoparticles and a resuspending material
US8101593B2 (en) 2009-03-03 2012-01-24 Kythera Biopharmaceuticals, Inc. Formulations of deoxycholic acid and salts thereof
CN102058528B (en) * 2009-11-13 2012-12-12 中国科学院上海药物研究所 Daidzein micelles and preparation method thereof
GB2480632A (en) 2010-05-25 2011-11-30 Kythera Biopharmaceuticals Inc Preparation of 12-keto and 12-alpha-hydroxy steroids
MX363465B (en) 2011-02-18 2019-03-25 Kythera Biopharmaceuticals Inc Treatment of submental fat.
US8653058B2 (en) 2011-04-05 2014-02-18 Kythera Biopharmaceuticals, Inc. Compositions comprising deoxycholic acid and salts thereof suitable for use in treating fat deposits
EP2857043B1 (en) * 2012-05-31 2019-01-23 Terumo Kabushiki Kaisha pH-SENSITIVE CARRIER AND METHOD FOR PRODUCTION THEREOF, pH-SENSITIVE MEDICINE AND pH-SENSITIVE PHARMACEUTICAL COMPOSITION EACH CONTAINING SAID CARRIER, AND CULTURE METHOD USING SAID pH-SENSITIVE MEDICINE OR SAID pH-SENSITIVE PHARMACEUTICAL COMPOSITION
US9321749B1 (en) 2012-07-25 2016-04-26 Globavir Biosciences, Inc. Heterocyclic compounds and uses thereof
CA3178035A1 (en) 2012-12-24 2014-07-03 Neurogastrx, Inc. Methods for treating gi tract disorders
US9844554B2 (en) 2014-06-24 2017-12-19 Neurogastrx, Inc. Prodrugs of metopimazine
CN110876719B (en) * 2018-09-06 2022-08-09 中国人民解放军军事科学院军事医学研究院 Vitamin K1 injection and preparation method thereof
US10836757B1 (en) 2020-04-02 2020-11-17 Neurogastrx, Inc. Polymorphic forms of metopimazine

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE575616C (en) * 1928-12-14 1933-04-29 Hans Much Dr Process for the production of stable, clear, aqueous solutions of lipoids, fats or resins
GB706607A (en) 1951-07-31 1954-03-31 Roche Products Ltd Process for the manufacture of dispersable solutions of fat soluble vitamins
DE932083C (en) * 1954-03-31 1955-08-22 Upha Chem Pharm Praeparate G M Process for the production of stable aqueous injection solutions of 2-methyl-5, 8-dimethoxy-furanochromone
DE1089510B (en) * 1959-03-23 1960-09-22 Rudolf Reiss Dr Process for the preparation of aqueous, injectable solutions of 2-methoxy-4-allylphenoxyacetic acid-N, N-diaethylamide
US3044931A (en) * 1960-01-27 1962-07-17 Geigy Chem Corp Aryloxy acetic acid amides: process for parenteral application
NL126750C (en) * 1960-12-05
US3639597A (en) * 1968-02-02 1972-02-01 Merck & Co Inc Pharmaceutical compositions containing cholanic acid conjugates
GB1317184A (en) * 1969-06-20 1973-05-16 Glaxo Lab Ltd Steroid-containing pharmaceutical preparations
US3900561A (en) * 1970-12-17 1975-08-19 Glaxo Lab Ltd Pharmaceutical compositions
US3917830A (en) * 1970-12-17 1975-11-04 Glaxo Lab Ltd Steroidal anaesthetic composition for intraveneous injection
US4017616A (en) * 1972-01-21 1977-04-12 American Home Products Corporation Parenteral benzodiazepine compositions
AU461715B2 (en) * 1972-01-21 1975-05-19 American Home Products Corporation Parenteral benzodiazepine compositions
DE2315609A1 (en) * 1973-03-29 1974-10-17 Holzhueter Hermann Stable, aqs. indomethacin solns. prepn. - using a dehydrocholic acid salt as solvent aid, with improved activity
DE2433173C3 (en) * 1974-07-10 1980-02-07 J. Pfrimmer & Co, 8520 Erlangen Use of cholanic acid derivatives

Also Published As

Publication number Publication date
NL189072C (en) 1993-01-04
AU2684677A (en) 1979-01-11
IL52458A0 (en) 1977-10-31
SE7708059L (en) 1978-01-13
DK314777A (en) 1978-01-13
LU90037I2 (en) 1997-06-13
NL189072B (en) 1992-08-03
FR2358161A1 (en) 1978-02-10
GB1587076A (en) 1981-03-25
MY8500263A (en) 1985-12-31
DK149483C (en) 1986-12-15
SE448516B (en) 1987-03-02
IL52458A (en) 1980-10-26
JPS6051448B2 (en) 1985-11-14
PH16333A (en) 1983-09-05
FR2358161B1 (en) 1980-07-25
CA1082596A (en) 1980-07-29
HK26584A (en) 1984-03-30
IT1202370B (en) 1989-02-09
DK149483B (en) 1986-06-30
DE2730570A1 (en) 1978-01-19
IE46037B1 (en) 1983-02-09
AU517249B2 (en) 1981-07-16
US4158707A (en) 1979-06-19
DE2730570C2 (en) 1989-01-19
NL7707641A (en) 1978-01-16
NZ184564A (en) 1979-12-11
FR2423219A1 (en) 1979-11-16
FR2423219B1 (en) 1980-10-24
LU77708A1 (en) 1978-09-14
JPS539314A (en) 1978-01-27

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Legal Events

Date Code Title Description
MK9A Patent expired