IE780862L - Naphthyridines - Google Patents

Naphthyridines

Info

Publication number
IE780862L
IE780862L IE780862A IE86278A IE780862L IE 780862 L IE780862 L IE 780862L IE 780862 A IE780862 A IE 780862A IE 86278 A IE86278 A IE 86278A IE 780862 L IE780862 L IE 780862L
Authority
IE
Ireland
Prior art keywords
naphthyridines
novel
gb1566693a
possess
beta
Prior art date
Application number
IE780862A
Other versions
IE46874B1 (en
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Publication of IE780862L publication Critical patent/IE780862L/en
Publication of IE46874B1 publication Critical patent/IE46874B1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Novel naphthyridines, which possess a 3-amino-2-OR-propoxy substituent, have the following formulae <IMAGE> in which R<2> and Z are defined in claim 1. The novel compounds can be used in pharmaceutical preparations for producing a beta -adrenergic blockage or for treating hypertension. [GB1566693A]
IE862/78A 1977-05-02 1978-05-01 Naphthyridines IE46874B1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US79275277A 1977-05-02 1977-05-02

Publications (2)

Publication Number Publication Date
IE780862L true IE780862L (en) 1978-11-02
IE46874B1 IE46874B1 (en) 1983-10-19

Family

ID=25157956

Family Applications (1)

Application Number Title Priority Date Filing Date
IE862/78A IE46874B1 (en) 1977-05-02 1978-05-01 Naphthyridines

Country Status (12)

Country Link
JP (1) JPS53136000A (en)
BE (1) BE866544A (en)
CH (1) CH634320A5 (en)
DE (1) DE2818290A1 (en)
DK (1) DK166478A (en)
FR (1) FR2389624B1 (en)
GB (1) GB1566693A (en)
IE (1) IE46874B1 (en)
IT (1) IT1107210B (en)
LU (1) LU79551A1 (en)
NL (1) NL7804168A (en)
SE (1) SE7804318L (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4233332A (en) * 1978-03-16 1980-11-11 Firmenich Sa Use of bicyclic nitrogen-containing derivatives as flavoring ingredients
DE3169626D1 (en) * 1981-02-27 1985-05-02 American Home Prod Antihypertensive agents
AU634561B2 (en) * 1989-07-27 1993-02-25 Eli Lilly And Company Naphthyridine derivatives
US5240916A (en) * 1989-07-27 1993-08-31 Dowelanco Naphthyridine derivatives
CN103476417A (en) 2011-02-18 2013-12-25 梅迪维新技术公司 Compounds and methods of treating diabetes
EP2887805A4 (en) * 2012-08-22 2016-08-17 Medivation Technologies Inc Compounds and methods for treatment of hypertension

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1006725A (en) * 1948-08-31 1952-04-28 Cilag Spa New derivatives of naphthyridine and process for their preparation
GB743901A (en) * 1952-02-18 1956-01-25 Ward Blenkinsop & Co Ltd Substituted pyridines and process for the production thereof
GB745348A (en) * 1952-03-10 1956-02-22 Howards Ilford Ltd Basically substituted pyridines and process for the production thereof
CH581113A5 (en) * 1973-10-08 1976-10-29 Sandoz Ag

Also Published As

Publication number Publication date
JPS53136000A (en) 1978-11-28
BE866544A (en) 1978-10-30
NL7804168A (en) 1978-11-06
IT7849081A0 (en) 1978-04-26
GB1566693A (en) 1980-05-08
CH634320A5 (en) 1983-01-31
IT1107210B (en) 1985-11-25
FR2389624B1 (en) 1982-12-17
DE2818290A1 (en) 1978-11-09
IE46874B1 (en) 1983-10-19
SE7804318L (en) 1978-11-03
DK166478A (en) 1978-11-03
FR2389624A1 (en) 1978-12-01
JPS6115875B2 (en) 1986-04-26
LU79551A1 (en) 1979-02-02

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