IE781477L - IMIDAZO £2,1-a| ISOINDOLES - Google Patents

IMIDAZO £2,1-a| ISOINDOLES

Info

Publication number
IE781477L
IE781477L IE147778A IE147778A IE781477L IE 781477 L IE781477 L IE 781477L IE 147778 A IE147778 A IE 147778A IE 147778 A IE147778 A IE 147778A IE 781477 L IE781477 L IE 781477L
Authority
IE
Ireland
Prior art keywords
indicated
formula
isoindoles
imidazo
reacted
Prior art date
Application number
IE147778A
Other versions
IE47210B1 (en
Original Assignee
Delmar Chem
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Delmar Chem filed Critical Delmar Chem
Publication of IE781477L publication Critical patent/IE781477L/en
Publication of IE47210B1 publication Critical patent/IE47210B1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/44—Iso-indoles; Hydrogenated iso-indoles
    • C07D209/46—Iso-indoles; Hydrogenated iso-indoles with an oxygen atom in position 1
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/44—Iso-indoles; Hydrogenated iso-indoles
    • C07D209/48—Iso-indoles; Hydrogenated iso-indoles with oxygen atoms in positions 1 and 3, e.g. phthalimide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/44—Iso-indoles; Hydrogenated iso-indoles
    • C07D209/50—Iso-indoles; Hydrogenated iso-indoles with oxygen and nitrogen atoms in positions 1 and 3
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/87—Benzo [c] furans; Hydrogenated benzo [c] furans
    • C07D307/88—Benzo [c] furans; Hydrogenated benzo [c] furans with one oxygen atom directly attached in position 1 or 3

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

The process for the preparation of known imidazo[2,1-a]isoindoles of the formula (I) indicated in Claim 1 leads via intermediates, some of which are new, of the formula (II) indicated in Claim 1, which are reacted with appropriate alkylating agents, to salts of the formula (III) indicated in Claim 1; these salts are reacted with ethylene- diamine to give an intermediate of the formula (IV) indicated in Claim 1, which is finally hydrolysed to the title compound (I). <IMAGE> [GB1601701A]
IE147778A 1977-07-22 1978-07-21 Improvements in the production of heterocyclic benzamide compounds IE47210B1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB3079877A GB1601701A (en) 1977-07-22 1977-07-22 Production of heterocyclic benzamide compounds

Publications (2)

Publication Number Publication Date
IE781477L true IE781477L (en) 1979-01-22
IE47210B1 IE47210B1 (en) 1984-01-11

Family

ID=10313296

Family Applications (1)

Application Number Title Priority Date Filing Date
IE147778A IE47210B1 (en) 1977-07-22 1978-07-21 Improvements in the production of heterocyclic benzamide compounds

Country Status (8)

Country Link
JP (1) JPS5424894A (en)
AR (1) AR220143A1 (en)
BE (1) BE869194A (en)
CA (1) CA1105028A (en)
CH (1) CH642370A5 (en)
DE (1) DE2831773A1 (en)
GB (1) GB1601701A (en)
IE (1) IE47210B1 (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4743980B2 (en) * 2001-03-13 2011-08-10 独立行政法人科学技術振興機構 Pyrrolinone derivative and method for producing the same
GB0419481D0 (en) * 2004-09-02 2004-10-06 Cancer Rec Tech Ltd Isoindolin-1-one derivatives
GB0811643D0 (en) 2008-06-25 2008-07-30 Cancer Rec Tech Ltd New therapeutic agents
GB201517217D0 (en) 2015-09-29 2015-11-11 Astex Therapeutics Ltd And Cancer Res Technology Ltd Pharmaceutical compounds
GB201517216D0 (en) 2015-09-29 2015-11-11 Cancer Res Technology Ltd And Astex Therapeutics Ltd Pharmaceutical compounds
GB201704965D0 (en) 2017-03-28 2017-05-10 Astex Therapeutics Ltd Pharmaceutical compounds
GB201704966D0 (en) 2017-03-28 2017-05-10 Astex Therapeutics Ltd Pharmaceutical compounds

Also Published As

Publication number Publication date
IE47210B1 (en) 1984-01-11
BE869194A (en) 1978-11-16
JPS5424894A (en) 1979-02-24
AR220143A1 (en) 1980-10-15
CA1105028A (en) 1981-07-14
GB1601701A (en) 1981-11-04
DE2831773A1 (en) 1979-02-08
CH642370A5 (en) 1984-04-13

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