IE781883L - Pyrrolidine derivatives. - Google Patents
Pyrrolidine derivatives.Info
- Publication number
- IE781883L IE781883L IE781883A IE188378A IE781883L IE 781883 L IE781883 L IE 781883L IE 781883 A IE781883 A IE 781883A IE 188378 A IE188378 A IE 188378A IE 781883 L IE781883 L IE 781883L
- Authority
- IE
- Ireland
- Prior art keywords
- pyrrolidine derivatives
- formula
- phloroglucinol
- therapeutics
- compounds
- Prior art date
Links
- 150000003235 pyrrolidines Chemical class 0.000 title 1
- 150000003839 salts Chemical class 0.000 abstract 2
- 239000002253 acid Substances 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 231100000252 nontoxic Toxicity 0.000 abstract 1
- 230000003000 nontoxic effect Effects 0.000 abstract 1
- 239000000810 peripheral vasodilating agent Substances 0.000 abstract 1
- 125000002444 phloroglucinyl group Chemical class [H]OC1=C([H])C(O[H])=C(*)C(O[H])=C1[H] 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/10—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms
- C07D295/104—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms with the ring nitrogen atoms and the doubly bound oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C07D295/108—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms with the ring nitrogen atoms and the doubly bound oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
New derivatives of phloroglucinol of formula <IMAGE> where R is H or CH3, and their acid addition salts are disclosed. The compounds of formula I and their non-toxic salts are useful in therapeutics as peripheral vasodilating agents.
[FR2404003A1]
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB3998277 | 1977-09-26 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IE781883L true IE781883L (en) | 1979-03-26 |
| IE47367B1 IE47367B1 (en) | 1984-03-07 |
Family
ID=10412559
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IE1883/78A IE47367B1 (en) | 1977-09-26 | 1978-09-18 | New phloroglucinol derivatives,their method of preparation and their use as pharmaceuticals |
Country Status (14)
| Country | Link |
|---|---|
| JP (1) | JPS5495562A (en) |
| AU (1) | AU523963B2 (en) |
| BE (1) | BE870717A (en) |
| CA (1) | CA1126738A (en) |
| CH (1) | CH633774A5 (en) |
| DE (1) | DE2858813C2 (en) |
| DK (1) | DK156395C (en) |
| ES (1) | ES473689A1 (en) |
| FR (1) | FR2404003A1 (en) |
| IE (1) | IE47367B1 (en) |
| IT (1) | IT1108172B (en) |
| LU (1) | LU80277A1 (en) |
| NL (1) | NL190720C (en) |
| SE (1) | SE436277B (en) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4273776A (en) | 1980-01-30 | 1981-06-16 | E. R. Squibb & Sons, Inc. | Antibacterial and antifungal derivatives of 3-(1H-imidazol-1-yl)-2-propen-1-ones |
| FR2504136A1 (en) * | 1981-04-15 | 1982-10-22 | Lafon Labor | (2,6-DIMETHOXY-4-HYDROXYPHENYL) - (3-PIPERIDINOPROPYL) -CETONE AND ITS ADDITION SALTS, THERAPEUTIC USE AND PREPARATION METHOD |
| DE3688917T2 (en) * | 1985-04-11 | 1994-02-10 | Nippon Kayaku Kk | Derivatives of an amino ketone. |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2092133B1 (en) * | 1970-05-06 | 1974-03-22 | Orsymonde | |
| FR2134218A1 (en) * | 1971-04-27 | 1972-12-08 | Penciolelli Madeleine | Phloroglucinol aminoketones - vasodilators and antispasmodics |
-
1978
- 1978-09-14 FR FR7826464A patent/FR2404003A1/en active Granted
- 1978-09-18 IE IE1883/78A patent/IE47367B1/en not_active IP Right Cessation
- 1978-09-21 SE SE7809916A patent/SE436277B/en not_active IP Right Cessation
- 1978-09-21 DK DK419178A patent/DK156395C/en not_active IP Right Cessation
- 1978-09-25 LU LU80277A patent/LU80277A1/en unknown
- 1978-09-25 IT IT69202/78A patent/IT1108172B/en active
- 1978-09-25 CH CH997678A patent/CH633774A5/en not_active IP Right Cessation
- 1978-09-25 BE BE2057301A patent/BE870717A/en not_active IP Right Cessation
- 1978-09-25 DE DE2858813A patent/DE2858813C2/de not_active Expired - Fee Related
- 1978-09-26 JP JP11756078A patent/JPS5495562A/en active Pending
- 1978-09-26 ES ES473689A patent/ES473689A1/en not_active Expired
- 1978-09-26 NL NL7809754A patent/NL190720C/en not_active IP Right Cessation
- 1978-09-26 AU AU40195/78A patent/AU523963B2/en not_active Expired
- 1978-09-26 CA CA312,144A patent/CA1126738A/en not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| NL7809754A (en) | 1979-03-28 |
| FR2404003A1 (en) | 1979-04-20 |
| SE7809916L (en) | 1979-03-27 |
| IT7869202A0 (en) | 1978-09-25 |
| BE870717A (en) | 1979-03-26 |
| IT1108172B (en) | 1985-12-02 |
| AU4019578A (en) | 1980-04-03 |
| DK419178A (en) | 1979-03-27 |
| CH633774A5 (en) | 1982-12-31 |
| FR2404003B1 (en) | 1981-07-31 |
| CA1126738A (en) | 1982-06-29 |
| DK156395C (en) | 1990-01-08 |
| AU523963B2 (en) | 1982-08-26 |
| NL190720B (en) | 1994-02-16 |
| NL190720C (en) | 1994-07-18 |
| DE2858813C2 (en) | 1993-07-01 |
| LU80277A1 (en) | 1979-06-01 |
| SE436277B (en) | 1984-11-26 |
| IE47367B1 (en) | 1984-03-07 |
| JPS5495562A (en) | 1979-07-28 |
| ES473689A1 (en) | 1979-05-01 |
| DK156395B (en) | 1989-08-14 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MM4A | Patent lapsed |