IE812677L - Process for production of cycloaliphatic keto-and¹hydroxy-amines - Google Patents
Process for production of cycloaliphatic keto-and¹hydroxy-aminesInfo
- Publication number
- IE812677L IE812677L IE812677A IE267781A IE812677L IE 812677 L IE812677 L IE 812677L IE 812677 A IE812677 A IE 812677A IE 267781 A IE267781 A IE 267781A IE 812677 L IE812677 L IE 812677L
- Authority
- IE
- Ireland
- Prior art keywords
- image
- keto
- cycloaliphatic
- amines
- production
- Prior art date
Links
- 239000002253 acid Substances 0.000 abstract 2
- 229910052739 hydrogen Inorganic materials 0.000 abstract 2
- 239000001257 hydrogen Substances 0.000 abstract 2
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 2
- 125000004178 (C1-C4) alkyl group Chemical group 0.000 abstract 1
- 125000004169 (C1-C6) alkyl group Chemical group 0.000 abstract 1
- KSHKNZCWWVVNHT-UHFFFAOYSA-N 3-(1,3-oxazolidin-3-ylmethyl)-1,3-oxazolidine Chemical class C1COCN1CN1CCOC1 KSHKNZCWWVVNHT-UHFFFAOYSA-N 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 125000005843 halogen group Chemical group 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 150000002576 ketones Chemical class 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 229920006395 saturated elastomer Polymers 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C1/00—Preparation of hydrocarbons from one or more compounds, none of them being a hydrocarbon
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C27/00—Processes involving the simultaneous production of more than one class of oxygen-containing compounds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
- C07D263/04—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Compounds of the formula:- <IMAGE> in which X represents the group <IMAGE> or <IMAGE> R2 represents hydrogen or a C1-C6-alkyl group and R3 represents hydrogen or a hydroxy group whilst R1 represents the adamantyl radical or a saturated or monounsaturated C3-C16-cycloalkyl radical which may be substituted by a C1-C4-alkyl group or by a halogen atom, and their acid addition salts are prepared by reacting corresponding N,N'-methylene- bis-oxazolidines with ketones of the formula R1-CO-C(R2)H2 in acid medium, optionally followed by reduction.
[GB2087397A]
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE3043350 | 1980-11-17 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IE812677L true IE812677L (en) | 1982-05-17 |
| IE52081B1 IE52081B1 (en) | 1987-06-10 |
Family
ID=6116998
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IE2677/81A IE52081B1 (en) | 1980-11-17 | 1981-11-16 | A new process for the production of cycloaliphatic keto-and hydroxy-amines |
Country Status (17)
| Country | Link |
|---|---|
| AT (1) | AT379379B (en) |
| CA (1) | CA1187489A (en) |
| CS (1) | CS227018B2 (en) |
| DD (1) | DD202285A5 (en) |
| DK (1) | DK507581A (en) |
| EG (1) | EG15343A (en) |
| ES (1) | ES507158A0 (en) |
| FI (1) | FI77649C (en) |
| GB (1) | GB2087397A (en) |
| GR (1) | GR76339B (en) |
| HU (1) | HU185671B (en) |
| IE (1) | IE52081B1 (en) |
| LU (1) | LU83751A1 (en) |
| MX (1) | MX7032E (en) |
| NO (1) | NO152294C (en) |
| PT (1) | PT73979B (en) |
| YU (1) | YU42253B (en) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0211254A3 (en) * | 1985-07-31 | 1988-05-04 | ASTA Pharma Aktiengesellschaft | Cycloaliphatic ketoamines |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FI70205C (en) * | 1978-05-17 | 1986-09-15 | Degussa | FOERFARANDE FOER FRAMSTAELLNING AV NYA TERAPEUTISKT ANVAENDBARA L- / 3-HYDROXI-3-PHENYLPROPYL- (2) / - / 3-OXO-PROPYL / AMINER |
-
1981
- 1981-11-11 DD DD81234784A patent/DD202285A5/en unknown
- 1981-11-12 CS CS818317A patent/CS227018B2/en unknown
- 1981-11-12 PT PT73979A patent/PT73979B/en unknown
- 1981-11-12 GR GR66507A patent/GR76339B/el unknown
- 1981-11-13 LU LU83751A patent/LU83751A1/en unknown
- 1981-11-16 NO NO813881A patent/NO152294C/en unknown
- 1981-11-16 ES ES507158A patent/ES507158A0/en active Granted
- 1981-11-16 GB GB8134515A patent/GB2087397A/en not_active Withdrawn
- 1981-11-16 IE IE2677/81A patent/IE52081B1/en unknown
- 1981-11-16 AT AT0493281A patent/AT379379B/en not_active IP Right Cessation
- 1981-11-16 HU HU813427A patent/HU185671B/en unknown
- 1981-11-16 FI FI813623A patent/FI77649C/en not_active IP Right Cessation
- 1981-11-16 MX MX819763U patent/MX7032E/en unknown
- 1981-11-16 YU YU2690/81A patent/YU42253B/en unknown
- 1981-11-16 CA CA000390117A patent/CA1187489A/en not_active Expired
- 1981-11-16 DK DK507581A patent/DK507581A/en unknown
- 1981-11-17 EG EG673/81A patent/EG15343A/en active
Also Published As
| Publication number | Publication date |
|---|---|
| NO152294C (en) | 1985-09-04 |
| ES8206441A1 (en) | 1982-08-16 |
| ES507158A0 (en) | 1982-08-16 |
| DD202285A5 (en) | 1983-09-07 |
| YU269081A (en) | 1983-09-30 |
| AT379379B (en) | 1985-12-27 |
| IE52081B1 (en) | 1987-06-10 |
| DK507581A (en) | 1982-05-18 |
| FI77649C (en) | 1989-04-10 |
| EG15343A (en) | 1986-09-30 |
| PT73979B (en) | 1983-04-26 |
| FI813623L (en) | 1982-05-18 |
| NO813881L (en) | 1982-05-18 |
| PT73979A (en) | 1981-12-01 |
| CS227018B2 (en) | 1984-04-16 |
| LU83751A1 (en) | 1982-02-18 |
| HU185671B (en) | 1985-03-28 |
| GB2087397A (en) | 1982-05-26 |
| CA1187489A (en) | 1985-05-21 |
| GR76339B (en) | 1984-08-04 |
| MX7032E (en) | 1987-03-03 |
| FI77649B (en) | 1988-12-30 |
| NO152294B (en) | 1985-05-28 |
| ATA493281A (en) | 1985-05-15 |
| YU42253B (en) | 1988-06-30 |
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