IE821261L - Preparation of pyrazine derivatives. - Google Patents

Preparation of pyrazine derivatives.

Info

Publication number
IE821261L
IE821261L IE821261A IE126182A IE821261L IE 821261 L IE821261 L IE 821261L IE 821261 A IE821261 A IE 821261A IE 126182 A IE126182 A IE 126182A IE 821261 L IE821261 L IE 821261L
Authority
IE
Ireland
Prior art keywords
formula
preparation
image
pyrazine derivatives
diaminomaleonitrile
Prior art date
Application number
IE821261A
Other versions
IE52992B1 (en
Original Assignee
Erba Farmitalia
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Erba Farmitalia filed Critical Erba Farmitalia
Publication of IE821261L publication Critical patent/IE821261L/en
Publication of IE52992B1 publication Critical patent/IE52992B1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
    • C07D241/10—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D241/14—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D241/24—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Saccharide Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

Abstract

The present invention relates to the preparation of pyrazine derivatives of the formula <IMAGE> in which R1 is hydrogen or lower alkyl; R2 is hydroxyl, alkoxy having 1 to 6 C atoms or a group of the formula <IMAGE> in which R3 and R4 independently of one another represent hydrogen or alkyl having 1 to 6 C atoms, and n is 1 or zero. Compounds of the formula (I) in which n is zero are prepared starting from diaminomaleonitrile of the formula <IMAGE> The diaminomaleonitrile and a compound of the formula CHOCOR1 are subjected to a condensation reaction, and the resulting compounds are reacted with an acid. [FR2506768A1]
IE1261/82A 1981-05-28 1982-05-26 Preparation of pyrazine derivatives IE52992B1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB8116263 1981-05-28

Publications (2)

Publication Number Publication Date
IE821261L true IE821261L (en) 1982-11-28
IE52992B1 IE52992B1 (en) 1988-04-27

Family

ID=10522093

Family Applications (1)

Application Number Title Priority Date Filing Date
IE1261/82A IE52992B1 (en) 1981-05-28 1982-05-26 Preparation of pyrazine derivatives

Country Status (20)

Country Link
JP (1) JPS57200368A (en)
AT (1) AT387217B (en)
AU (1) AU8412682A (en)
BE (1) BE893317A (en)
CA (1) CA1237724A (en)
CH (1) CH649763A5 (en)
CS (1) CS226741B2 (en)
DE (1) DE3219407A1 (en)
DK (1) DK155325C (en)
FI (1) FI73669C (en)
FR (1) FR2506768B1 (en)
GR (1) GR76417B (en)
HU (1) HU187716B (en)
IE (1) IE52992B1 (en)
IL (1) IL65864A (en)
IT (1) IT1210478B (en)
NL (1) NL8202105A (en)
SE (1) SE462971B (en)
YU (1) YU42766B (en)
ZA (1) ZA823660B (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1201417B (en) * 1985-05-17 1989-02-02 Montedison Spa PROCEDURE FOR THE PREPARATION OF 2-CARBOXYPYRAZINE 4 OXIDE

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU470007B2 (en) * 1972-04-28 1976-02-26 Farmitalia Carlo Erba S.R.L. Pyrazine 4-oxide derivatives and process for their preparation
JPS565742B2 (en) * 1973-09-29 1981-02-06
JPS5134175A (en) * 1974-09-18 1976-03-23 Sagami Chem Res Pirajinjudotai no seizohoho
JPS52153980A (en) * 1976-06-17 1977-12-21 Nippon Soda Co Ltd Synthesis of 2,3-dicyanopyrazine
JPS5488280A (en) * 1977-12-20 1979-07-13 Nitsupou Kagaku Kk Manufacture of dicyanopyradines
JPS5488281A (en) * 1977-12-20 1979-07-13 Nitsupou Kagaku Kk Manufacture of pyrazine monocarboxylic acid

Also Published As

Publication number Publication date
DE3219407A1 (en) 1983-01-05
IE52992B1 (en) 1988-04-27
DK155325C (en) 1989-09-18
NL8202105A (en) 1982-12-16
FI73669C (en) 1987-11-09
AU8412682A (en) 1982-12-02
IL65864A0 (en) 1982-08-31
JPH0456034B2 (en) 1992-09-07
ZA823660B (en) 1983-03-30
AT387217B (en) 1988-12-27
SE462971B (en) 1990-09-24
CS226741B2 (en) 1984-04-16
ATA203682A (en) 1988-05-15
BE893317A (en) 1982-11-29
DK239482A (en) 1982-11-29
DK155325B (en) 1989-03-28
IT8221517A0 (en) 1982-05-27
FI73669B (en) 1987-07-31
DE3219407C2 (en) 1990-09-06
FI821832A0 (en) 1982-05-24
FR2506768A1 (en) 1982-12-03
YU113182A (en) 1985-03-20
IL65864A (en) 1985-08-30
FR2506768B1 (en) 1985-06-21
HU187716B (en) 1986-02-28
GR76417B (en) 1984-08-10
JPS57200368A (en) 1982-12-08
SE8203273L (en) 1982-11-29
CA1237724A (en) 1988-06-07
YU42766B (en) 1988-12-31
CH649763A5 (en) 1985-06-14
IT1210478B (en) 1989-09-14

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Legal Events

Date Code Title Description
MK9A Patent expired