IE821261L - Preparation of pyrazine derivatives. - Google Patents
Preparation of pyrazine derivatives.Info
- Publication number
- IE821261L IE821261L IE821261A IE126182A IE821261L IE 821261 L IE821261 L IE 821261L IE 821261 A IE821261 A IE 821261A IE 126182 A IE126182 A IE 126182A IE 821261 L IE821261 L IE 821261L
- Authority
- IE
- Ireland
- Prior art keywords
- formula
- preparation
- image
- pyrazine derivatives
- diaminomaleonitrile
- Prior art date
Links
- 238000002360 preparation method Methods 0.000 title abstract 2
- 150000003216 pyrazines Chemical class 0.000 title abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 3
- DPZSNGJNFHWQDC-ARJAWSKDSA-N (z)-2,3-diaminobut-2-enedinitrile Chemical compound N#CC(/N)=C(/N)C#N DPZSNGJNFHWQDC-ARJAWSKDSA-N 0.000 abstract 2
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 125000004432 carbon atom Chemical group C* 0.000 abstract 2
- 229910052739 hydrogen Inorganic materials 0.000 abstract 2
- 239000001257 hydrogen Substances 0.000 abstract 2
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 2
- 239000002253 acid Substances 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 238000006482 condensation reaction Methods 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
- C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
- C07D241/10—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
- C07D241/14—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D241/24—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Saccharide Compounds (AREA)
Abstract
The present invention relates to the preparation of pyrazine derivatives of the formula <IMAGE> in which R1 is hydrogen or lower alkyl; R2 is hydroxyl, alkoxy having 1 to 6 C atoms or a group of the formula <IMAGE> in which R3 and R4 independently of one another represent hydrogen or alkyl having 1 to 6 C atoms, and n is 1 or zero. Compounds of the formula (I) in which n is zero are prepared starting from diaminomaleonitrile of the formula <IMAGE> The diaminomaleonitrile and a compound of the formula CHOCOR1 are subjected to a condensation reaction, and the resulting compounds are reacted with an acid.
[FR2506768A1]
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB8116263 | 1981-05-28 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IE821261L true IE821261L (en) | 1982-11-28 |
| IE52992B1 IE52992B1 (en) | 1988-04-27 |
Family
ID=10522093
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IE1261/82A IE52992B1 (en) | 1981-05-28 | 1982-05-26 | Preparation of pyrazine derivatives |
Country Status (20)
| Country | Link |
|---|---|
| JP (1) | JPS57200368A (en) |
| AT (1) | AT387217B (en) |
| AU (1) | AU8412682A (en) |
| BE (1) | BE893317A (en) |
| CA (1) | CA1237724A (en) |
| CH (1) | CH649763A5 (en) |
| CS (1) | CS226741B2 (en) |
| DE (1) | DE3219407A1 (en) |
| DK (1) | DK155325C (en) |
| FI (1) | FI73669C (en) |
| FR (1) | FR2506768B1 (en) |
| GR (1) | GR76417B (en) |
| HU (1) | HU187716B (en) |
| IE (1) | IE52992B1 (en) |
| IL (1) | IL65864A (en) |
| IT (1) | IT1210478B (en) |
| NL (1) | NL8202105A (en) |
| SE (1) | SE462971B (en) |
| YU (1) | YU42766B (en) |
| ZA (1) | ZA823660B (en) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1201417B (en) * | 1985-05-17 | 1989-02-02 | Montedison Spa | PROCEDURE FOR THE PREPARATION OF 2-CARBOXYPYRAZINE 4 OXIDE |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1361967A (en) * | 1972-04-28 | 1974-07-30 | Erba Carlo Spa | Pyrazine 4-oxide derivatives and process for their preparation |
| JPS565742B2 (en) * | 1973-09-29 | 1981-02-06 | ||
| JPS5134175A (en) * | 1974-09-18 | 1976-03-23 | Sagami Chem Res | Pirajinjudotai no seizohoho |
| JPS52153980A (en) * | 1976-06-17 | 1977-12-21 | Nippon Soda Co Ltd | Synthesis of 2,3-dicyanopyrazine |
| JPS5488281A (en) * | 1977-12-20 | 1979-07-13 | Nitsupou Kagaku Kk | Manufacture of pyrazine monocarboxylic acid |
| JPS5488280A (en) * | 1977-12-20 | 1979-07-13 | Nitsupou Kagaku Kk | Manufacture of dicyanopyradines |
-
1982
- 1982-05-21 NL NL8202105A patent/NL8202105A/en active Search and Examination
- 1982-05-24 IL IL65864A patent/IL65864A/en not_active IP Right Cessation
- 1982-05-24 AT AT0203682A patent/AT387217B/en not_active IP Right Cessation
- 1982-05-24 DE DE19823219407 patent/DE3219407A1/en active Granted
- 1982-05-24 FI FI821832A patent/FI73669C/en not_active IP Right Cessation
- 1982-05-25 AU AU84126/82A patent/AU8412682A/en not_active Abandoned
- 1982-05-25 GR GR68246A patent/GR76417B/el unknown
- 1982-05-25 FR FR8209038A patent/FR2506768B1/en not_active Expired
- 1982-05-25 CS CS823842A patent/CS226741B2/en unknown
- 1982-05-25 CA CA000403636A patent/CA1237724A/en not_active Expired
- 1982-05-26 SE SE8203273A patent/SE462971B/en not_active IP Right Cessation
- 1982-05-26 ZA ZA823660A patent/ZA823660B/en unknown
- 1982-05-26 JP JP57088153A patent/JPS57200368A/en active Granted
- 1982-05-26 IE IE1261/82A patent/IE52992B1/en not_active IP Right Cessation
- 1982-05-27 BE BE0/208187A patent/BE893317A/en not_active IP Right Cessation
- 1982-05-27 HU HU821712A patent/HU187716B/en unknown
- 1982-05-27 IT IT8221517A patent/IT1210478B/en active Protection Beyond IP Right Term
- 1982-05-27 DK DK239482A patent/DK155325C/en not_active IP Right Cessation
- 1982-05-27 YU YU1131/82A patent/YU42766B/en unknown
- 1982-05-27 CH CH3285/82A patent/CH649763A5/en not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| AT387217B (en) | 1988-12-27 |
| DE3219407A1 (en) | 1983-01-05 |
| AU8412682A (en) | 1982-12-02 |
| HU187716B (en) | 1986-02-28 |
| ZA823660B (en) | 1983-03-30 |
| IT8221517A0 (en) | 1982-05-27 |
| CH649763A5 (en) | 1985-06-14 |
| SE462971B (en) | 1990-09-24 |
| IE52992B1 (en) | 1988-04-27 |
| DE3219407C2 (en) | 1990-09-06 |
| JPH0456034B2 (en) | 1992-09-07 |
| SE8203273L (en) | 1982-11-29 |
| FR2506768A1 (en) | 1982-12-03 |
| FR2506768B1 (en) | 1985-06-21 |
| IL65864A (en) | 1985-08-30 |
| YU42766B (en) | 1988-12-31 |
| DK155325C (en) | 1989-09-18 |
| DK239482A (en) | 1982-11-29 |
| CA1237724A (en) | 1988-06-07 |
| ATA203682A (en) | 1988-05-15 |
| FI73669B (en) | 1987-07-31 |
| IL65864A0 (en) | 1982-08-31 |
| BE893317A (en) | 1982-11-29 |
| FI821832A0 (en) | 1982-05-24 |
| CS226741B2 (en) | 1984-04-16 |
| FI73669C (en) | 1987-11-09 |
| YU113182A (en) | 1985-03-20 |
| NL8202105A (en) | 1982-12-16 |
| GR76417B (en) | 1984-08-10 |
| IT1210478B (en) | 1989-09-14 |
| JPS57200368A (en) | 1982-12-08 |
| DK155325B (en) | 1989-03-28 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MK9A | Patent expired |