IE822840L - Derivatives of 2-phenyl-morpholine - Google Patents
Derivatives of 2-phenyl-morpholineInfo
- Publication number
- IE822840L IE822840L IE822840A IE284082A IE822840L IE 822840 L IE822840 L IE 822840L IE 822840 A IE822840 A IE 822840A IE 284082 A IE284082 A IE 284082A IE 822840 L IE822840 L IE 822840L
- Authority
- IE
- Ireland
- Prior art keywords
- morpholine
- phenyl
- acid addition
- addition salts
- derivatives
- Prior art date
Links
- ZLNGFYDJXZZFJP-UHFFFAOYSA-N 2-phenylmorpholine Chemical class C1NCCOC1C1=CC=CC=C1 ZLNGFYDJXZZFJP-UHFFFAOYSA-N 0.000 title abstract 3
- 239000002253 acid Substances 0.000 abstract 4
- 150000003839 salts Chemical class 0.000 abstract 4
- RLMOVFUYZBCTKX-UHFFFAOYSA-N 4-ethyl-2-phenylmorpholine Chemical compound C1N(CC)CCOC1C1=CC=CC=C1 RLMOVFUYZBCTKX-UHFFFAOYSA-N 0.000 abstract 2
- UBQMBBSAKGENED-UHFFFAOYSA-N 4-methyl-2-(2-methylphenyl)morpholine Chemical compound C1N(C)CCOC1C1=CC=CC=C1C UBQMBBSAKGENED-UHFFFAOYSA-N 0.000 abstract 2
- 239000003814 drug Substances 0.000 abstract 2
- 229940079593 drug Drugs 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
- C07D265/28—1,4-Oxazines; Hydrogenated 1,4-oxazines
- C07D265/30—1,4-Oxazines; Hydrogenated 1,4-oxazines not condensed with other rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Psychiatry (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Pain & Pain Management (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
1. Claims for the Contracting States : BE, CH, DE, FR, GB, IT, LI, LU, NL, SE 2-phenyl-morpholine derivative, useful in particular in therapeutics, characterized in that it is selected from the group constituted by : (i) the 2-phenyl-4-ethyl-morpholine and its acid addition salts, and (ii) the 2-o-tolyl-4-methyl-morpholine and its acid addition salts. 1. Claims for the Contracting State : AT Use of a 2-phenyl-morpholine derivative selected from the group constituted by : (i) 2-phenyl-4-ethyl-morpholine and its acid addition salts, and (ii) 2-o-tolyl-4-methyl-morpholine and its acid addition salts, for the preparation of a drug.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR8122507A FR2517305B1 (en) | 1981-12-01 | 1981-12-01 | NOVEL 2-PHENYL-MORPHOLINE DERIVATIVES AND THEIR USE IN THERAPEUTICS |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IE822840L true IE822840L (en) | 1983-06-01 |
| IE54330B1 IE54330B1 (en) | 1989-08-30 |
Family
ID=9264557
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IE2840/82A IE54330B1 (en) | 1981-12-01 | 1982-11-29 | Derivatives of 2-phenyl-morpholine and therapeutic compositions |
Country Status (12)
| Country | Link |
|---|---|
| EP (1) | EP0080940B1 (en) |
| JP (1) | JPS58103377A (en) |
| AT (1) | ATE18043T1 (en) |
| AU (1) | AU9100482A (en) |
| CA (1) | CA1189861A (en) |
| DE (1) | DE3269247D1 (en) |
| DK (1) | DK531582A (en) |
| ES (1) | ES517779A0 (en) |
| FR (1) | FR2517305B1 (en) |
| GR (1) | GR77037B (en) |
| IE (1) | IE54330B1 (en) |
| ZA (1) | ZA828758B (en) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2553410B1 (en) * | 1983-10-14 | 1986-05-16 | Lafon Labor | NOVEL 2-TOLYL-MORPHOLINE DERIVATIVES USEFUL IN THERAPEUTICS |
| FR2564462B1 (en) * | 1984-05-16 | 1986-11-21 | Lafon Labor | 2-PHENYL-MORPHOLINE DERIVATIVES USEFUL IN THERAPEUTICS |
| GB9108629D0 (en) * | 1991-04-23 | 1991-06-12 | Wellcome Found | Heterocyclic pharmaceutical compounds,preparation and use |
| WO1993015052A1 (en) * | 1992-01-28 | 1993-08-05 | Smithkline Beecham Plc | Compounds as calcium channel antagonists |
| CA2422055A1 (en) | 2000-09-11 | 2002-03-21 | Sepracor, Inc. | Ligands for monoamine receptors and transporters, and methods of use thereof (neurotransmission) |
| US7294637B2 (en) | 2000-09-11 | 2007-11-13 | Sepracor, Inc. | Method of treating addiction or dependence using a ligand for a monamine receptor or transporter |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2835669A (en) * | 1958-05-20 | Process for the production of substi- | ||
| GB851311A (en) * | 1958-04-02 | 1960-10-12 | Geigy Ag J R | Morpholine compounds and their production |
| FR1535615A (en) * | 1967-06-26 | 1968-08-09 | Ct Europ De Rech S Mauvernay | Process for obtaining tetrahydro-1, 4-oxazines substituted in 2, 4 and in 2, 2, 4 |
| FR2471378A1 (en) * | 1979-12-14 | 1981-06-19 | Lafon Labor | Alkylated 2:phenyl morpholine derivs. - having antidepressant and cardiovascular activity, prepd. by cyclising hydroxyalkyl phenyl ethanol(s) |
-
1981
- 1981-12-01 FR FR8122507A patent/FR2517305B1/en not_active Expired
-
1982
- 1982-11-17 GR GR69842A patent/GR77037B/el unknown
- 1982-11-25 EP EP82402147A patent/EP0080940B1/en not_active Expired
- 1982-11-25 AT AT82402147T patent/ATE18043T1/en not_active IP Right Cessation
- 1982-11-25 DE DE8282402147T patent/DE3269247D1/en not_active Expired
- 1982-11-29 ES ES517779A patent/ES517779A0/en active Granted
- 1982-11-29 ZA ZA828758A patent/ZA828758B/en unknown
- 1982-11-29 IE IE2840/82A patent/IE54330B1/en unknown
- 1982-11-30 CA CA000416708A patent/CA1189861A/en not_active Expired
- 1982-11-30 DK DK531582A patent/DK531582A/en not_active Application Discontinuation
- 1982-11-30 AU AU91004/82A patent/AU9100482A/en not_active Abandoned
- 1982-12-01 JP JP57211199A patent/JPS58103377A/en active Granted
Also Published As
| Publication number | Publication date |
|---|---|
| ZA828758B (en) | 1983-09-28 |
| ATE18043T1 (en) | 1986-03-15 |
| CA1189861A (en) | 1985-07-02 |
| ES8308317A1 (en) | 1983-08-16 |
| GR77037B (en) | 1984-09-04 |
| DK531582A (en) | 1983-06-02 |
| JPH0254831B2 (en) | 1990-11-22 |
| EP0080940A2 (en) | 1983-06-08 |
| EP0080940B1 (en) | 1986-02-19 |
| DE3269247D1 (en) | 1986-03-27 |
| IE54330B1 (en) | 1989-08-30 |
| FR2517305A1 (en) | 1983-06-03 |
| ES517779A0 (en) | 1983-08-16 |
| JPS58103377A (en) | 1983-06-20 |
| AU9100482A (en) | 1983-06-09 |
| EP0080940A3 (en) | 1983-07-06 |
| FR2517305B1 (en) | 1985-10-25 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| EP0614913A3 (en) | Dynorphin derivatives. | |
| NZ190439A (en) | 2,4-disubstituted-5-thiazole carboxylic acid derivatives and methods and compositions for reducing herbicidal injury | |
| PT66271A (en) | Process for the preparation of a parasiticidal composition containing 4,5-dichloroimidazole-2-carboxilic acid derivatives and salts thereof | |
| IE822840L (en) | Derivatives of 2-phenyl-morpholine | |
| ZA792773B (en) | Derivatives of 4,5-dihydro-4-oxofuran-2-carboxylic acid | |
| NZ334119A (en) | Use of pentynoic acid derivatives as neurotrophic and antiproliferative agents | |
| NZ192286A (en) | 1,3,4-thiadiazole-2/carboxylic acid derivatives fungicidal and nematocidal compositions | |
| IE42672L (en) | Thieno-tetrahydropyridine derivatives | |
| ATE3542T1 (en) | PHARMACEUTICAL ALCOXYPROPANOLAMINES AND PROCESSES FOR THEIR PREPARATION. | |
| ZA793720B (en) | Substituted 2-phenylamino-imidazoline-(2)derivatives,acid addition salts thereof,processes for their preparation,and pharmaceutical compositions thereof | |
| GB2012266B (en) | 1,5 - cyclohexadienecarbocylic acid derivatives | |
| IL57217A0 (en) | 7-(2-( -(1,3-dithiolan-2-imino)substituted)-acetylamino)cephalo-sporanic acid derivatives | |
| AU551407B2 (en) | Crystalline human leukocyte interferon | |
| GB2093018B (en) | 6,8-difluoro-quinoline carboxylic acid derivatives | |
| IE780559L (en) | Furoyl- and thenoyl-aryloxyalkyl carboxylic acid | |
| IL56255A0 (en) | Substituted 1,4-cychlohexadiene carboxylic acid derivatives | |
| AU565183B2 (en) | 3-amino-1-phenoxy-2-propanol derivatives | |
| ZA793604B (en) | Substituted 2-phenylamino-imidazoline-(2)derivatives,acid addition salts thereof,processes for their preparation,and pharmaceutical compositions thereof | |
| JPS52122387A (en) | 7alpha-methoxycephalosporin derivatives and their preparation | |
| DE3262234D1 (en) | Pharmaceutical compositions with antalgic effect | |
| IL77922A (en) | 1,4-dihalogenobutane-2,3-diones,their preparation and their use as intermediate for producing 2-(2-aminothiazol-4-yl)glyoxylic acid derivatives or a salt thereof | |
| IE871642L (en) | 4-(3'trifluoromethylphenoxy)-benzoylacetic acid derivatives. | |
| ZA883610B (en) | A process for the preparation of 5-acylamino-2,4,6-triiodo-or tribromo-benzioc acid derivatives and the acid derivatives obtained by said process | |
| UA5591A1 (en) | Process for preparation of derivatives of 3-(2?)-pyridazinone, or pharmaceutically acceptable salts |