IE831597L - Synergistic antihypertensive pharmaceutical composition. - Google Patents
Synergistic antihypertensive pharmaceutical composition.Info
- Publication number
- IE831597L IE831597L IE831597A IE159783A IE831597L IE 831597 L IE831597 L IE 831597L IE 831597 A IE831597 A IE 831597A IE 159783 A IE159783 A IE 159783A IE 831597 L IE831597 L IE 831597L
- Authority
- IE
- Ireland
- Prior art keywords
- pharmaceutical composition
- combination
- components
- antihypertensive pharmaceutical
- synergistic antihypertensive
- Prior art date
Links
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 2
- 230000002195 synergetic effect Effects 0.000 title abstract 2
- 230000003276 anti-hypertensive effect Effects 0.000 title 1
- 206010020772 Hypertension Diseases 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- NDDAHWYSQHTHNT-UHFFFAOYSA-N indapamide Chemical compound CC1CC2=CC=CC=C2N1NC(=O)C1=CC=C(Cl)C(S(N)(=O)=O)=C1 NDDAHWYSQHTHNT-UHFFFAOYSA-N 0.000 abstract 1
- 229960004569 indapamide Drugs 0.000 abstract 1
- 230000003287 optical effect Effects 0.000 abstract 1
- 239000000825 pharmaceutical preparation Substances 0.000 abstract 1
- 238000002360 preparation method Methods 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/10—Antioedematous agents; Diuretics
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Epidemiology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
The present invention provides pharmaceutical compositions and preparations comprising a combination of indapamide and certain thiachromans, especially 8-(3-tert.-butylamino-2- hydroxypropoxy)-thiachroman, or a physiologically tolerable acid addition salt thereof. Each of the two components may be in the racemic form or in the form of an optical isomer. The components in combination have unexpected synergistic properties and can be used for treating hypertension.
[GB2123293A]
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR8212058A FR2529785A1 (en) | 1982-07-09 | 1982-07-09 | PHARMACEUTICAL COMPOSITION BASED ON INDAPAMIDE AND 8- (3-TERTBUTYLAMINO 2-HYDROXYPROPOXY) THIACHROMAN |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IE831597L true IE831597L (en) | 1984-01-09 |
| IE55364B1 IE55364B1 (en) | 1990-08-29 |
Family
ID=9275835
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IE1597/83A IE55364B1 (en) | 1982-07-09 | 1983-07-08 | Synergistic antihypertensive pharmaceutical composition |
Country Status (16)
| Country | Link |
|---|---|
| JP (1) | JPS5927813A (en) |
| AU (1) | AU557601B2 (en) |
| BE (1) | BE897251A (en) |
| CA (1) | CA1197191A (en) |
| CH (1) | CH655007A5 (en) |
| DE (1) | DE3324785C2 (en) |
| FR (1) | FR2529785A1 (en) |
| GB (1) | GB2123293B (en) |
| IE (1) | IE55364B1 (en) |
| IT (1) | IT1173729B (en) |
| LU (1) | LU84902A1 (en) |
| NL (1) | NL8302435A (en) |
| NZ (1) | NZ204849A (en) |
| OA (1) | OA07489A (en) |
| SE (1) | SE8303886L (en) |
| ZA (1) | ZA834978B (en) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HU196125B (en) * | 1985-02-05 | 1988-10-28 | Sandoz Ag | Process for producing pharmaceutical comprising 3-(aminopropoxy)-indole derivatives combined with diuretic |
| PL193976B1 (en) * | 2002-07-01 | 2007-04-30 | Pliva Krakow | Prolonged effect containing indapamide and method of manufacture of prolonged effect tablets containing indapamide |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1203691A (en) * | 1968-03-06 | 1970-09-03 | Science Union & Cie | New disubstituted n-amino indoline derivatives and process for preparing them |
| GB1308191A (en) * | 1970-04-06 | 1973-02-21 | Science Union & Cie | Thiochroman derivatives and a process for preparing them |
| DE2227423A1 (en) * | 1971-06-15 | 1972-12-21 | Ciba-Geigy Ag, Basel (Schweiz) | New pharmaceutical preparations |
-
1982
- 1982-07-09 FR FR8212058A patent/FR2529785A1/en active Granted
-
1983
- 1983-07-06 LU LU84902A patent/LU84902A1/en unknown
- 1983-07-07 IT IT48641/83A patent/IT1173729B/en active
- 1983-07-07 ZA ZA834978A patent/ZA834978B/en unknown
- 1983-07-07 SE SE8303886A patent/SE8303886L/en not_active Application Discontinuation
- 1983-07-08 CA CA000432068A patent/CA1197191A/en not_active Expired
- 1983-07-08 AU AU16702/83A patent/AU557601B2/en not_active Ceased
- 1983-07-08 OA OA58056A patent/OA07489A/en unknown
- 1983-07-08 NL NL8302435A patent/NL8302435A/en not_active Application Discontinuation
- 1983-07-08 CH CH3786/83A patent/CH655007A5/en not_active IP Right Cessation
- 1983-07-08 DE DE3324785A patent/DE3324785C2/en not_active Expired
- 1983-07-08 NZ NZ204849A patent/NZ204849A/en unknown
- 1983-07-08 GB GB08318512A patent/GB2123293B/en not_active Expired
- 1983-07-08 BE BE0/211143A patent/BE897251A/en not_active IP Right Cessation
- 1983-07-08 JP JP58124582A patent/JPS5927813A/en active Granted
- 1983-07-08 IE IE1597/83A patent/IE55364B1/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| SE8303886L (en) | 1984-01-10 |
| JPH0250084B2 (en) | 1990-11-01 |
| CH655007A5 (en) | 1986-03-27 |
| IT1173729B (en) | 1987-06-24 |
| FR2529785A1 (en) | 1984-01-13 |
| GB2123293A (en) | 1984-02-01 |
| FR2529785B1 (en) | 1984-12-07 |
| NZ204849A (en) | 1986-04-11 |
| GB8318512D0 (en) | 1983-08-10 |
| GB2123293B (en) | 1985-10-09 |
| SE8303886D0 (en) | 1983-07-07 |
| IE55364B1 (en) | 1990-08-29 |
| OA07489A (en) | 1985-03-31 |
| CA1197191A (en) | 1985-11-26 |
| LU84902A1 (en) | 1984-03-22 |
| IT8348641A0 (en) | 1983-07-07 |
| NL8302435A (en) | 1984-02-01 |
| ZA834978B (en) | 1984-03-28 |
| AU557601B2 (en) | 1986-12-24 |
| JPS5927813A (en) | 1984-02-14 |
| DE3324785C2 (en) | 1986-10-09 |
| DE3324785A1 (en) | 1984-01-12 |
| BE897251A (en) | 1984-01-09 |
| AU1670283A (en) | 1984-01-12 |
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