IE850213L - Dihydroxy dehydrovitamin d compound - Google Patents
Dihydroxy dehydrovitamin d compoundInfo
- Publication number
- IE850213L IE850213L IE850213A IE21385A IE850213L IE 850213 L IE850213 L IE 850213L IE 850213 A IE850213 A IE 850213A IE 21385 A IE21385 A IE 21385A IE 850213 L IE850213 L IE 850213L
- Authority
- IE
- Ireland
- Prior art keywords
- compound
- dehydrovitamin
- dihydroxy
- vitamin
- metabolites
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title abstract 3
- 150000003710 vitamin D derivatives Chemical class 0.000 abstract 2
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 abstract 1
- 208000029725 Metabolic bone disease Diseases 0.000 abstract 1
- 229930003316 Vitamin D Natural products 0.000 abstract 1
- QYSXJUFSXHHAJI-XFEUOLMDSA-N Vitamin D3 Natural products C1(/[C@@H]2CC[C@@H]([C@]2(CCC1)C)[C@H](C)CCCC(C)C)=C/C=C1\C[C@@H](O)CCC1=C QYSXJUFSXHHAJI-XFEUOLMDSA-N 0.000 abstract 1
- 229910052791 calcium Inorganic materials 0.000 abstract 1
- 239000011575 calcium Substances 0.000 abstract 1
- 239000002207 metabolite Substances 0.000 abstract 1
- 210000002966 serum Anatomy 0.000 abstract 1
- 235000019166 vitamin D Nutrition 0.000 abstract 1
- 239000011710 vitamin D Substances 0.000 abstract 1
- 229940046008 vitamin d Drugs 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/02—Nutrients, e.g. vitamins, minerals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
- A61P3/14—Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C401/00—Irradiation products of cholesterol or its derivatives; Vitamin D derivatives, 9,10-seco cyclopenta[a]phenanthrene or analogues obtained by chemical preparation without irradiation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
- C07J71/0036—Nitrogen-containing hetero ring
- C07J71/0042—Nitrogen only
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Diabetes (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Rheumatology (AREA)
- Endocrinology (AREA)
- Nutrition Science (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Steroid Compounds (AREA)
Abstract
Novel vitamin D derivative, 1$g(a),25-dihydroxy-22Z-dehydrovitamin D2?. The compound is characterized by unexpectedly high ability to raise serum calcium levels. The compound could therefore, find ready application as a substitute for vitamin D or its metabolites in the treatment of metabolic bone diseases or in other of their known applications.
[WO8503300A1]
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US57511484A | 1984-01-30 | 1984-01-30 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IE850213L true IE850213L (en) | 1985-07-30 |
| IE57936B1 IE57936B1 (en) | 1993-05-19 |
Family
ID=24299012
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IE213/85A IE57936B1 (en) | 1984-01-30 | 1985-01-29 | 1alpha,25-dihydroxy-22z-dehydrovitamin d compound |
Country Status (11)
| Country | Link |
|---|---|
| JP (1) | JPS61501147A (en) |
| AU (1) | AU587174B2 (en) |
| BE (1) | BE901601A (en) |
| CH (1) | CH665835A5 (en) |
| DE (2) | DE3590021T (en) |
| DK (1) | DK437685D0 (en) |
| FR (1) | FR2558828B1 (en) |
| GB (1) | GB2153358B (en) |
| IE (1) | IE57936B1 (en) |
| NL (1) | NL8520009A (en) |
| WO (1) | WO1985003300A1 (en) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS61501146A (en) * | 1984-01-30 | 1986-06-12 | ウイスコンシン アラムナイ リサ−チ フォンデ−ション | Side chain unsaturated 1-hydroxyvitamin D compound |
| AU584071B2 (en) * | 1984-03-05 | 1989-05-18 | Wisconsin Alumni Research Foundation | 1a-hydroxyvitamin d2 analogs and process for preparing same |
| DE3687377T2 (en) * | 1985-01-17 | 1993-04-29 | Wisconsin Alumni Res Found | VITAMIN-D-COMBINATIONS AND THEIR PRODUCTION METHOD. |
| NZ232734A (en) * | 1989-03-09 | 1991-11-26 | Wisconsin Alumni Res Found | 19-nor vitamin d derivatives and pharmaceutical compositions |
| US5246925A (en) * | 1989-03-09 | 1993-09-21 | Wisconsin Alumni Research Foundation | 19-nor-vitamin D compounds for use in treating hyperparathyroidism |
| CA1333616C (en) * | 1989-03-09 | 1994-12-20 | Hector F. Deluca | 19-nor-vitamin d compounds |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4260549A (en) * | 1979-05-21 | 1981-04-07 | Wisconsin Alumni Research Foundation | Process for preparing 1α-hydroxylated compounds |
| EP0015122B1 (en) * | 1979-02-15 | 1983-09-14 | Teijin Limited | New 25-hydroxy-24-oxocholestane derivatives and preparation thereof |
| US4284577A (en) * | 1979-02-16 | 1981-08-18 | Sachiko Yamada | Novel vitamin D3 derivative and process for preparing the same |
-
1985
- 1985-01-07 DE DE19853590021 patent/DE3590021T/en active Pending
- 1985-01-07 DE DE19853590021 patent/DE3590021C2/en not_active Expired - Lifetime
- 1985-01-07 WO PCT/US1985/000017 patent/WO1985003300A1/en not_active Ceased
- 1985-01-07 NL NL8520009A patent/NL8520009A/en unknown
- 1985-01-07 AU AU38372/85A patent/AU587174B2/en not_active Ceased
- 1985-01-07 JP JP60500432A patent/JPS61501147A/en active Granted
- 1985-01-07 CH CH4260/85A patent/CH665835A5/en not_active IP Right Cessation
- 1985-01-29 FR FR8501230A patent/FR2558828B1/en not_active Expired
- 1985-01-29 GB GB08502161A patent/GB2153358B/en not_active Expired
- 1985-01-29 BE BE0/214412A patent/BE901601A/en not_active IP Right Cessation
- 1985-01-29 IE IE213/85A patent/IE57936B1/en not_active IP Right Cessation
- 1985-09-27 DK DK437685A patent/DK437685D0/en not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| GB8502161D0 (en) | 1985-02-27 |
| DK437685A (en) | 1985-09-27 |
| GB2153358A (en) | 1985-08-21 |
| DE3590021T (en) | 1986-01-23 |
| AU3837285A (en) | 1985-08-09 |
| IE57936B1 (en) | 1993-05-19 |
| CH665835A5 (en) | 1988-06-15 |
| NL8520009A (en) | 1985-12-02 |
| BE901601A (en) | 1985-05-17 |
| AU587174B2 (en) | 1989-08-10 |
| JPS61501147A (en) | 1986-06-12 |
| JPH0455425B2 (en) | 1992-09-03 |
| DE3590021C2 (en) | 1992-09-10 |
| FR2558828A1 (en) | 1985-08-02 |
| FR2558828B1 (en) | 1987-11-20 |
| GB2153358B (en) | 1987-07-22 |
| DK437685D0 (en) | 1985-09-27 |
| WO1985003300A1 (en) | 1985-08-01 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MM4A | Patent lapsed |