IE851906L - Interferons - Google Patents

Interferons

Info

Publication number
IE851906L
IE851906L IE851906A IE190685A IE851906L IE 851906 L IE851906 L IE 851906L IE 851906 A IE851906 A IE 851906A IE 190685 A IE190685 A IE 190685A IE 851906 L IE851906 L IE 851906L
Authority
IE
Ireland
Prior art keywords
interferons
organisms
produced
type
dna sequences
Prior art date
Application number
IE851906A
Other versions
IE58942B1 (en
Original Assignee
Boehringer Ingelheim Int
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE3428370A external-priority patent/DE3428370A1/en
Priority claimed from DE19853505060 external-priority patent/DE3505060A1/en
Application filed by Boehringer Ingelheim Int filed Critical Boehringer Ingelheim Int
Publication of IE851906L publication Critical patent/IE851906L/en
Publication of IE58942B1 publication Critical patent/IE58942B1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/555—Interferons [IFN]
    • C07K14/56—IFN-alpha
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/555—Interferons [IFN]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Public Health (AREA)
  • Toxicology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Plant Pathology (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Electrotherapy Devices (AREA)

Abstract

The type I interferon peptides encoded by the genetic DNA sequences are called omega-interferons and are produced using appropriate expression vehicles and organisms.
IE190685A 1984-08-01 1985-07-31 New genetic sequences, the interferon peptides of type 1 encoded by them and the microorganisms producing these interferons IE58942B1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE3428370A DE3428370A1 (en) 1984-08-01 1984-08-01 Interferon, genetic sequences which code therefor, and organisms producing these
DE19853505060 DE3505060A1 (en) 1985-02-14 1985-02-14 Type I interferons, genetic sequences which code therefor, and organisms producing these

Publications (2)

Publication Number Publication Date
IE851906L true IE851906L (en) 1986-02-01
IE58942B1 IE58942B1 (en) 1993-12-01

Family

ID=25823496

Family Applications (1)

Application Number Title Priority Date Filing Date
IE190685A IE58942B1 (en) 1984-08-01 1985-07-31 New genetic sequences, the interferon peptides of type 1 encoded by them and the microorganisms producing these interferons

Country Status (21)

Country Link
EP (1) EP0170204B1 (en)
JP (2) JP2566909B2 (en)
KR (1) KR0136799B1 (en)
AT (1) ATE67786T1 (en)
AU (1) AU600653B2 (en)
BG (1) BG60445B2 (en)
CA (1) CA1340184C (en)
DD (1) DD246318A5 (en)
DE (1) DE3584198D1 (en)
DK (1) DK175194B1 (en)
ES (2) ES8609475A1 (en)
FI (1) FI90667C (en)
GR (1) GR851866B (en)
HK (1) HK187896A (en)
HU (1) HU205779B (en)
IE (1) IE58942B1 (en)
IL (1) IL75963A (en)
MX (1) MX9203645A (en)
NO (1) NO177863C (en)
NZ (1) NZ212937A (en)
PT (1) PT80901B (en)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5231176A (en) * 1984-08-27 1993-07-27 Genentech, Inc. Distinct family DNA encoding of human leukocyte interferons
DE3607835A1 (en) * 1986-03-10 1987-09-24 Boehringer Ingelheim Int HYBRID INTERFERONS, THEIR USE AS MEDICINAL PRODUCTS AND AS INTERMEDIATE PRODUCTS FOR THE PRODUCTION OF ANTIBODIES AND THE USE THEREOF AND METHOD FOR THEIR PRODUCTION
EP0490233A1 (en) * 1986-03-10 1992-06-17 BOEHRINGER INGELHEIM INTERNATIONAL GmbH Monoclonal antibodies against Bgl III-hybrid interferons, their use and process for preparing them
US4863727A (en) * 1986-04-09 1989-09-05 Cetus Corporation Combination therapy using interleukin-2 and tumor necrosis factor
DE3633323A1 (en) * 1986-10-01 1988-04-07 Boehringer Ingelheim Int NEW MONOCLONAL ANTIBODIES AGAINST IFN-OMEGA, METHOD FOR THE PRODUCTION THEREOF AND THEIR USE FOR CLEANING AND DETECTING IFN-OMEGA
DE3635867A1 (en) * 1986-10-22 1988-05-11 Boehringer Ingelheim Int NEW YEAR EXPRESSION VECTORS FOR IFN-OMEGA, METHOD FOR THEIR PRODUCTION AND USE THEREOF
ATE550042T1 (en) 1997-11-20 2012-04-15 Vical Inc TREATMENT OF CANCER USING CYTOKINE-EXPRESSING POLYNUCLEOTIDES AND COMPOSITIONS THEREOF
WO2000040273A2 (en) * 1999-01-08 2000-07-13 Vical Incorporated Treatment of viral diseases using an interferon omega expressing polynucleotide
KR101495616B1 (en) * 2002-03-07 2015-02-26 아이드게노쉬쉐 테흐니쉐 호흐슐레 쥬리히 System and method for the production of recombinant glycosylated protein in a prokaryotic host
IL163806A0 (en) 2002-03-07 2005-12-18 Eidgenoess Tech Hochschule System and method for the production of recombinant glycosylated proteins in a prokaryotic host
PL1615945T3 (en) 2003-04-09 2012-03-30 Ratiopharm Gmbh Glycopegylation methods and proteins/peptides produced by the methods
WO2004096852A1 (en) * 2003-04-25 2004-11-11 The Institute Of Microbiology And Epidemiology, Academy Of Military Medical Sciemces, Pla A RECOMBINANT HUMAN INTERFERON ϖ, THE METHOD FOR EXPRESSING IT AND THE USES OF IT
ES2353814T3 (en) 2005-05-11 2011-03-07 Eth Zuerich RECOMBINANT N-GLYCOSILATED PROTEINS OF PROCEDURAL CELLS.
CN101983070B (en) 2008-02-20 2016-03-30 格林考瓦因有限公司 The recombinant N-glycosylated proteins that origin comes from prokaryotic cell prepares bioconjugates
NO2501406T3 (en) 2009-11-19 2018-05-19
EP3281639B1 (en) 2010-05-06 2020-11-11 GlaxoSmithKline Biologicals S.A. Capsular gram-positive bacteria bioconjugate vaccines
WO2013024156A2 (en) 2011-08-17 2013-02-21 INSERM (Institut National de la Santé et de la Recherche Médicale) Combinations of anti-hcv-entry factor antibodies and interferons for the treatment and the prevention of hcv infection
WO2013024158A1 (en) 2011-08-17 2013-02-21 INSERM (Institut National de la Santé et de la Recherche Médicale) Combinations of protein kinase inhibitors and interferons or of protein kinase inhibitors and direct acting antivirals for the treatment and the prevention of hcv infection
WO2014033266A1 (en) 2012-08-31 2014-03-06 INSERM (Institut National de la Santé et de la Recherche Médicale) Anti-sr-bi antibodies for the inhibition of hepatitis c virus infection

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU1946283A (en) * 1982-08-18 1984-03-07 Cetus Corporation Interferon-alpha 6l
CA1217440A (en) * 1982-08-18 1987-02-03 Michael A. Innis INTERFERON .alpha. 6L
DE3247922A1 (en) * 1982-12-24 1984-06-28 Boehringer Ingelheim International GmbH, 6507 Ingelheim DNA SEQUENCES, THEIR PRODUCTION, PLASMIDES CONTAINING THESE SEQUENCES AND THE USE THEREOF FOR THE SYNTHESIS OF EUKARYOTIC GENE PRODUCTS IN PROKARYOTS
DE3574145D1 (en) * 1984-08-27 1989-12-14 Genentech Inc Novel, distinct family of human leukocyte interferons, compositions containing them, methods for their production, and dna and transfected hosts therefor

Also Published As

Publication number Publication date
JP2567195B2 (en) 1996-12-25
GR851866B (en) 1985-12-02
DK346385A (en) 1986-02-02
IL75963A (en) 1992-05-25
PT80901A (en) 1985-09-01
FI90667B (en) 1993-11-30
ES545725A0 (en) 1986-08-01
AU4554985A (en) 1986-02-06
JPH06181771A (en) 1994-07-05
EP0170204A2 (en) 1986-02-05
NO177863C (en) 1995-12-06
FI852956A0 (en) 1985-07-31
FI852956L (en) 1986-02-02
IL75963A0 (en) 1985-12-31
JPS61181381A (en) 1986-08-14
ATE67786T1 (en) 1991-10-15
EP0170204A3 (en) 1988-02-17
DK346385D0 (en) 1985-07-30
DK175194B1 (en) 2004-07-05
JP2566909B2 (en) 1996-12-25
AU600653B2 (en) 1990-08-23
NO853012L (en) 1986-02-03
MX9203645A (en) 1992-09-01
PT80901B (en) 1989-01-17
HU205779B (en) 1992-06-29
BG60445B2 (en) 1995-03-31
ES8609475A1 (en) 1986-08-01
KR0136799B1 (en) 1998-04-25
ES552431A0 (en) 1987-09-01
HUT39477A (en) 1986-09-29
NO177863B (en) 1995-08-28
FI90667C (en) 1994-03-10
DE3584198D1 (en) 1991-10-31
EP0170204B1 (en) 1991-09-25
CA1340184C (en) 1998-12-15
NZ212937A (en) 1991-08-27
KR870001310A (en) 1987-03-13
IE58942B1 (en) 1993-12-01
ES8708013A1 (en) 1987-09-01
DD246318A5 (en) 1987-06-03
HK187896A (en) 1996-10-18

Similar Documents

Publication Publication Date Title
IE851906L (en) Interferons
EP0177568A4 (en) Recombinant dna molecules.
AU553400B2 (en) Recombinant dna for producing interferon
EP0658627A3 (en) Recombinant DNA with interferon-alpha promoter.
ZA81103B (en) Dna sequences ,recombinant dna molecules dna molecules and processes for producing human interferon -like polypeptides
AU2964489A (en) Dna sequences, recombinant dna molecules and processes for producing human immune interferon-like polypeptides
NZ221119A (en) Proteins with factor viii activity produced by microorganisms produced by genetic engineering
DE68927511D1 (en) DNA sequences encoding polypeptides with beta-1,3-glucanase activity
AU544218B2 (en) Unglycosylated interferon
IL68790A0 (en) Microbiologically produced alpha-and beta-interferons,dna sequences which code for these interferons,microorganisms which contain this genetic information and their preparation
GB8404378D0 (en) Dna sequence recombinant dna molecules
DE3377220D1 (en) Recombinant dna, microorganism transformed therewith and use thereof
TW342413B (en) Novel toxins isolated from Bracon Hebetor
SG134394G (en) Genetic sequences, type I interferon peptide coded by them, and these organisms producing the same
PH31199A (en) Coding, promoter and regulator sequences of irf-1.
HRP921091B1 (en) Dna sequences, recombinant dna molecules and processes for producing human fibroplast interferon-like polypeptides
ZA812189B (en) Dna sequences, recombinant dna molecules and processes for producing human fibroblast interferon-like polypeptides
KE3669A (en) Dna sequences,recombinant dna molecules and processes for producing human interferon-alpha like polypeptides
NZ215148A (en) Dna sequence encoding non-human animal interferon, expression vehicles and transformants
ATE75255T1 (en) PEPTIDE AND GENE CODING FOR IT.
MX9708877A (en) 'delta'p62, variants thereof, nucleic acid sequences and uses thereof.

Legal Events

Date Code Title Description
MK9A Patent expired