IE861284L - Controlled release ketoprofen. - Google Patents
Controlled release ketoprofen.Info
- Publication number
- IE861284L IE861284L IE861284A IE128486A IE861284L IE 861284 L IE861284 L IE 861284L IE 861284 A IE861284 A IE 861284A IE 128486 A IE128486 A IE 128486A IE 861284 L IE861284 L IE 861284L
- Authority
- IE
- Ireland
- Prior art keywords
- ketoprofen
- controlled release
- weight
- release ketoprofen
- gb2190287a
- Prior art date
Links
- DKYWVDODHFEZIM-UHFFFAOYSA-N ketoprofen Chemical compound OC(=O)C(C)C1=CC=CC(C(=O)C=2C=CC=CC=2)=C1 DKYWVDODHFEZIM-UHFFFAOYSA-N 0.000 title abstract 3
- 229960000991 ketoprofen Drugs 0.000 title abstract 3
- 238000013270 controlled release Methods 0.000 title 1
- 239000011230 binding agent Substances 0.000 abstract 1
- 230000003111 delayed effect Effects 0.000 abstract 1
- 239000002702 enteric coating Substances 0.000 abstract 1
- 238000009505 enteric coating Methods 0.000 abstract 1
- 238000009472 formulation Methods 0.000 abstract 1
- 230000005484 gravity Effects 0.000 abstract 1
- 229910010272 inorganic material Inorganic materials 0.000 abstract 1
- 239000011147 inorganic material Substances 0.000 abstract 1
- 239000003094 microcapsule Substances 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 231100000252 nontoxic Toxicity 0.000 abstract 1
- 230000003000 nontoxic effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1611—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5015—Organic compounds, e.g. fats, sugars
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Inorganic Chemistry (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
Abstract
Delayed release ketoprofen formulations are in the form of microcapsules and comprise a core containing: 20-60% by weight of ketoprofen; 10-40% by weight of a sphere-forming binder; and 20-70% of a non-toxic, inert inorganic material having a specific gravity in the range 1.5-3.5 and less than 5% moisture; and an enteric coating.
[GB2190287A]
Priority Applications (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IE861284A IE861284L (en) | 1986-05-14 | 1986-05-14 | Controlled release ketoprofen. |
| ZA873373A ZA873373B (en) | 1986-05-14 | 1987-05-12 | Controlled release ketoprofen pharmaceutical formulation |
| GB8711274A GB2190287B (en) | 1986-05-14 | 1987-05-13 | Controlled release ketoprofen pharmaceutical formulation |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IE861284A IE861284L (en) | 1986-05-14 | 1986-05-14 | Controlled release ketoprofen. |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IE861284L true IE861284L (en) | 1987-11-14 |
Family
ID=11024891
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IE861284A IE861284L (en) | 1986-05-14 | 1986-05-14 | Controlled release ketoprofen. |
Country Status (3)
| Country | Link |
|---|---|
| GB (1) | GB2190287B (en) |
| IE (1) | IE861284L (en) |
| ZA (1) | ZA873373B (en) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB8705083D0 (en) * | 1987-03-04 | 1987-04-08 | Euro Celtique Sa | Spheroids |
| GB8913889D0 (en) * | 1989-06-16 | 1989-08-02 | May & Baker Ltd | New compositions of matter |
| US5260072A (en) * | 1990-08-30 | 1993-11-09 | Mcneil-Ppc, Inc. | Rotogranulations and taste masking coatings for preparation of chewable pharmaceutical tablets |
| CA2052679C (en) * | 1990-08-30 | 1997-12-02 | Edward J. Roche | Rotogranulations and taste masking coatings for preparation of chewable pharmaceutical tablets |
| US5683719A (en) * | 1990-11-22 | 1997-11-04 | British Technology Group Limited | Controlled release compositions |
| GB9025372D0 (en) * | 1990-11-22 | 1991-01-09 | Nat Res Dev | Pharmaceutical dosage forms |
| WO1993017673A1 (en) * | 1992-03-03 | 1993-09-16 | Top Gold Pty., Limited | Sustained release analgesics |
| US5958458A (en) * | 1994-06-15 | 1999-09-28 | Dumex-Alpharma A/S | Pharmaceutical multiple unit particulate formulation in the form of coated cores |
-
1986
- 1986-05-14 IE IE861284A patent/IE861284L/en unknown
-
1987
- 1987-05-12 ZA ZA873373A patent/ZA873373B/en unknown
- 1987-05-13 GB GB8711274A patent/GB2190287B/en not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| GB8711274D0 (en) | 1987-06-17 |
| GB2190287A (en) | 1987-11-18 |
| ZA873373B (en) | 1987-11-03 |
| GB2190287B (en) | 1989-12-06 |
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