IE882255L - Preparation of quinolonecarboxylic acids - Google Patents
Preparation of quinolonecarboxylic acidsInfo
- Publication number
- IE882255L IE882255L IE882255A IE225588A IE882255L IE 882255 L IE882255 L IE 882255L IE 882255 A IE882255 A IE 882255A IE 225588 A IE225588 A IE 225588A IE 882255 L IE882255 L IE 882255L
- Authority
- IE
- Ireland
- Prior art keywords
- preparation
- quinolonecarboxylic acids
- acids
- quinolonecarboxylic
- intermediates
- Prior art date
Links
- 239000002253 acid Substances 0.000 title abstract 2
- 150000007513 acids Chemical class 0.000 title abstract 2
- 239000000543 intermediate Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
- C07D215/54—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3
- C07D215/56—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3 with oxygen atoms in position 4
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Quinoline Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
A novel method for the preparation of intermediates for pharmaceutically active quinolonecarboxylic acids in a single-step method.
[EP0300311A2]
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19873724466 DE3724466A1 (en) | 1987-07-24 | 1987-07-24 | PROCESS FOR THE PREPARATION OF CHINOLON CARBOXYANESE |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IE882255L true IE882255L (en) | 1989-01-24 |
| IE63654B1 IE63654B1 (en) | 1995-05-31 |
Family
ID=6332237
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IE225588A IE63654B1 (en) | 1987-07-24 | 1988-07-22 | Process for the preparation of quinolonecarboxylic acids |
Country Status (23)
| Country | Link |
|---|---|
| EP (1) | EP0300311B1 (en) |
| JP (1) | JP2812956B2 (en) |
| KR (1) | KR970010175B1 (en) |
| CN (1) | CN1030911A (en) |
| AR (1) | AR243509A1 (en) |
| AT (1) | ATE111898T1 (en) |
| AU (1) | AU602226B2 (en) |
| CA (1) | CA1333715C (en) |
| DD (1) | DD281806A5 (en) |
| DE (2) | DE3724466A1 (en) |
| DK (1) | DK174855B1 (en) |
| ES (1) | ES2058186T3 (en) |
| FI (1) | FI883452A7 (en) |
| HU (1) | HU205082B (en) |
| IE (1) | IE63654B1 (en) |
| IL (1) | IL87185A (en) |
| NO (1) | NO174773C (en) |
| NZ (1) | NZ225502A (en) |
| PH (1) | PH25098A (en) |
| PT (1) | PT88078B (en) |
| SU (1) | SU1660582A3 (en) |
| UA (1) | UA8018A1 (en) |
| ZA (1) | ZA885332B (en) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5093515A (en) * | 1987-08-14 | 1992-03-03 | Asahi Glass Company Ltd. | Fluorinated benzoyl compounds |
| DE4015299A1 (en) * | 1990-05-12 | 1991-11-14 | Bayer Ag | METHOD FOR PRODUCING 3-AMINO-2- (HET) -AROYL-ACRYLIC ACID DERIVATIVES |
| ES2039301B1 (en) * | 1991-11-20 | 1994-05-16 | Genesis Para La Investigacion | PROCEDURE FOR OBTAINING NEW USEFUL SYNTHESIS INTERMEDIATES FOR THE PREPARATION OF FLUOROQUINOLONS. |
| DE4342186A1 (en) | 1993-12-10 | 1995-06-14 | Bayer Ag | One-pot process for the production of 3-quinolonecarboxylic acid derivatives |
| FI970427A7 (en) * | 1994-08-02 | 1997-03-26 | Procter & Gamble | Method for preparing antimicrobial compounds |
| DE19826050A1 (en) | 1998-06-12 | 1999-12-16 | Bayer Ag | Process for the preparation of quinolonic and naphthyridonecarboxylic acids and their esters |
| ATE245140T1 (en) | 1998-11-18 | 2003-08-15 | Asahi Glass Co Ltd | DERIVATIVES OF AMINOACRYLIC ACID AND A METHOD FOR PRODUCING THE SAME |
| US6803469B2 (en) * | 2002-08-05 | 2004-10-12 | The Procter & Gamble Company | Process for preparing quinolone antibiotic intermediates |
| US20080139574A1 (en) | 2006-11-30 | 2008-06-12 | Cadila Healthcare Limited | Novel quinoline derivatives |
| CN101781299B (en) * | 2010-01-13 | 2012-06-27 | 杭州师范大学 | One-pot synthesis method for key intermediate of carbostyril medicaments |
| CN104292159B (en) * | 2014-10-10 | 2016-12-07 | 浙江同丰医药化工有限公司 | A kind of preparation method of norfloxacin, ciprofloxacin and enrofloxacin |
| CN111269131B (en) * | 2020-03-12 | 2021-12-28 | 江苏飞宇医药科技股份有限公司 | Process for preparing cyclopropyl ethyl amide by taking tri-n-propylamine as acid acceptor |
| CN115385856A (en) * | 2022-09-05 | 2022-11-25 | 常州大学 | Method for synthesizing norfloxacin intermediate by one-pot method |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2808070A1 (en) * | 1978-02-24 | 1979-08-30 | Bayer Ag | PROCESS FOR THE PRODUCTION OF 4-PYRIDONE-3-CARBONIC ACIDS AND / OR DERIVATIVES |
| DE3142854A1 (en) * | 1981-10-29 | 1983-05-11 | Bayer Ag, 5090 Leverkusen | 1-CYCLOPROPYL-6-FLUOR-1,4-DIHYDRO-4-OXO-7-PIPERAZINO-CHINOLINE-3-CARBONIC ACIDS, METHOD FOR THE PRODUCTION THEREOF AND THEIR CONTAINING ANTIBACTERIAL AGENTS |
| DE3318145A1 (en) * | 1983-05-18 | 1984-11-22 | Bayer Ag, 5090 Leverkusen | 7-AMINO-1-CYCLOPROPYL-6,8-DIFLUOR-1,4-DIHYDRO-4-OXO-3-CHINOLINE CARBONIC ACIDS, METHOD FOR THE PRODUCTION THEREOF AND THEIR CONTAINING ANTIBACTERIAL AGENTS |
| DE3426486A1 (en) * | 1984-07-18 | 1986-01-30 | Bayer Ag, 5090 Leverkusen | METHOD FOR PRODUCING CHINOLONIC AND NAPHTHYRIDONE CARBONIC ACIDS |
| UA7018A1 (en) * | 1984-09-29 | 1995-03-31 | "Байер АГ" | METHOD OF OBTAINING ACRYLIC ACID DERIVATIVES |
| DE3502935A1 (en) * | 1984-09-29 | 1986-04-10 | Bayer Ag, 5090 Leverkusen | 3-AMINO-2-BENZOYL-ACRYLIC ACID DERIVATIVES AND A METHOD FOR THE PRODUCTION THEREOF |
| DE3441788A1 (en) * | 1984-11-15 | 1986-05-15 | Bayer Ag, 5090 Leverkusen | ALKYL-1-CYCLOPROPYL-1,4-DIHYDRO-4-OXO-3-CHINOLINE CARBONIC ACIDS, METHOD FOR THE PRODUCTION THEREOF AND THE ANTIBACTERIAL AGENTS CONTAINING THEM |
| JPS6259263A (en) * | 1985-09-10 | 1987-03-14 | Kyorin Pharmaceut Co Ltd | Quinolonecarboxylic acid derivative |
-
1987
- 1987-07-24 DE DE19873724466 patent/DE3724466A1/en not_active Withdrawn
-
1988
- 1988-07-01 PH PH37150A patent/PH25098A/en unknown
- 1988-07-07 NO NO883046A patent/NO174773C/en not_active IP Right Cessation
- 1988-07-11 DE DE3851588T patent/DE3851588D1/en not_active Expired - Lifetime
- 1988-07-11 EP EP88111034A patent/EP0300311B1/en not_active Expired - Lifetime
- 1988-07-11 AT AT88111034T patent/ATE111898T1/en not_active IP Right Cessation
- 1988-07-11 ES ES88111034T patent/ES2058186T3/en not_active Expired - Lifetime
- 1988-07-14 AU AU19024/88A patent/AU602226B2/en not_active Expired
- 1988-07-20 SU SU88A patent/SU1660582A3/en active
- 1988-07-20 UA UA4356111A patent/UA8018A1/en unknown
- 1988-07-21 IL IL87185A patent/IL87185A/en not_active IP Right Cessation
- 1988-07-21 FI FI883452A patent/FI883452A7/en not_active Application Discontinuation
- 1988-07-21 NZ NZ225502A patent/NZ225502A/en unknown
- 1988-07-21 JP JP63180478A patent/JP2812956B2/en not_active Expired - Lifetime
- 1988-07-21 AR AR88311472A patent/AR243509A1/en active
- 1988-07-22 PT PT88078A patent/PT88078B/en not_active IP Right Cessation
- 1988-07-22 DK DK198804124A patent/DK174855B1/en not_active IP Right Cessation
- 1988-07-22 ZA ZA885332A patent/ZA885332B/en unknown
- 1988-07-22 IE IE225588A patent/IE63654B1/en not_active IP Right Cessation
- 1988-07-22 HU HU883878A patent/HU205082B/en unknown
- 1988-07-22 CA CA000572825A patent/CA1333715C/en not_active Expired - Lifetime
- 1988-07-22 DD DD88318209A patent/DD281806A5/en not_active IP Right Cessation
- 1988-07-23 CN CN88104633A patent/CN1030911A/en active Pending
- 1988-07-23 KR KR88009300A patent/KR970010175B1/en not_active Expired - Lifetime
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MK9A | Patent expired |